Clinical trials: Idiopathic Subglottic Stenosis, active
Idiopathic Subglottic Stenosis
Adjuvant Steroid Outcomes in Idiopathic Subglottic Stenosis
This study will examine the ability of steroid injections into the site of stenosis following surgical dilation to delay the need for repeated surgical dilations.
- Trial name
- ASTRO (NCT07228104)
- Testing
- Triamcinolone 0.1%
- Where
- 10 sites in United States
- Volunteers
- 226 people
- Sponsor
- Johns Hopkins University
Idiopathic Subglottic Tracheal Stenosis
Voice Quality Analysis of Patients With Laryngotracheal Stenosis
The investigators previously demonstrated that voice changes are common in patients with Laryngotracheal Stenosis (LTS), and patients typically report an improvement in voice outcomes following endoscopic dilation.
- Trial name
- NCT06161077
- Testing
- Voice Biomarker Screening Too
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Idiopathic Subglottic Stenosis, Subglottic Stenosis (SGS)
A Phase I Evaluation of the Safety and Tolerability of Pirfenidone in Idiopathic Subglottic Stenosis
Idiopathic subglottic stenosis (iSGS) is a rare condition where scar tissue forms just below the vocal cords and in the upper windpipe, making the airway narrow.
- Trial name
- NCT07654517
- Testing
- Pirfenidone 267 MG [Esbriet]
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's