Clinical trials: IOL, Cataract
Cataract
Post-Approval Study of the Tecnis® Toric IOL
This study is a prospective, multicenter, bilateral, non-randomized, open-label, comparative clinical study conducted at up to 80 sites in the USA.
- Trial name
- NCT02566083
- Testing
- non-toric intraocular lens, toric intraocular lens
- Where
- 44 sites in United States
- Volunteers
- 365 people
- Sponsor
- Abbott Medical Optics
Cataract Senile
Evaluation of Glistening, Visual Outcomes and General Safety 24 Months Post-IOL Implantation
Main evaluation of glistening at least 24 Months post-IOL implantation
- Trial name
- NCT07297719
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens
The purpose of this study is to evaluate the effect that placement and power of the AcrySof Toric has on post-operative visual acuity and spectacle independence for distance vision.
- Trial name
- NCT00760487
- Testing
- AcrySof Toric IOL
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Cataract
Visual Function With Contralateral AcrySof® ReSTOR® Aspheric SN6AD1 and SN6AD3
The objective of this study is to prospectively evaluate the visual parameters in a series of patients after phacoemulsification cataract surgery in a series of patients bilaterally implanted with the AcrySof® ReSTOR® Aspheric…
- Trial name
- NCT00710905
- Testing
- AcrySof ReSTOR Aspheric IOL models SN6AD1 and SN6AD3
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Alcon Research
Cataracts
Clinical Investigation of Visual Function After Bilateral Implantation of Two Presbyopia-Correcting Trifocal Intraocular Lenses (IOL)
The purpose of this study is to clinically evaluate the visual performance of two commercially available presbyopia-correcting Trifocal IOLs.
- Trial name
- NCT02691741
- Testing
- AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL, AT LISA® tri IOL
- Volunteers
- 215 people
- Sponsor
- Alcon Research
Cataract
Visual Outcomes of Subjects Bilaterally Implanted With ReSTOR Aspheric +4 vs. Tecnis or Acri.LISA
This is a study to compare visual outcomes of subjects bilaterally implanted w/ReSTOR to subjects bilaterally implanted with the Tecnis Multifocal Intraocular Lens (IOL) or Acri.LISA IOL
- Trial name
- NCT00721253
- Testing
- ReSTOR, Tecnis, Acri.LISA
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataracts
Low Cylinder Toric
Study evaluates the visual outcomes and patient satisfaction after implantation of a toric intraocular lens (IOL).
- Trial name
- NCT00732030
- Testing
- Toric IOL (SN60T3)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Alcon Research
Cataracts
Clinical Investigation of Corneal Incision Size After Intraocular Lens (IOL) Implantation
The purpose of this study is to compare corneal incision size after IOL implantation with the use of one of four IOL delivery systems (three preloaded IOL delivery systems and one manually loaded IOL delivery system).
- Trial name
- NCT02826421
- Testing
- UltraSert Preloaded Delivery System, iTec Preloaded Delivery System, iSert Preloaded Delivery System
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Cataract
Functional Vision With ACRYSOF® IQ IOLs Blue Light Filtration
The purpose of this study is to compare the reaction time (as measured by braking reaction time in seconds during simulated driving) under glare and no-glare conditions in subjects implanted with ACRYSOF® IQ intraocular lenses…
- Trial name
- NCT02219997
- Testing
- Clear clip-on glasses, Blue light filter clip-on glasses, ACRYSOF® IQ IOL
- Volunteers
- 90 people
- Sponsor
- Alcon Research
Cataract
Safety and Efficacy of a Violet Visible Light Blocking Intraocular Lens (IOL)
The purpose of this study is to evaluate the safety and effectiveness of a new investigational modified light transmission monofocal intraocular lens compared to a conventional intraocular lens (IOL).
- Trial name
- NCT00747227
- Testing
- modified light transmission intraocular lens, monofocal acrylic intraocular lens
- Where
- 11 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Aphakia
Clinical Investigation of the AcrySof IQ Vivity Extended Vision Intraocular Lens (IOL)
The purpose of this study is to compare the visual disturbance profile of an intraocular lens (IOL) using nondiffractive optics, the VIVITY IOL, to two diffractive IOLs in subjects requiring bilateral cataract surgery.
- Trial name
- NCT04098367
- Testing
- VIVITY, SYMFONY, AT LARA
- Where
- 12 sites in Australia, New Zealand
- Volunteers
- 222 people
- Sponsor
- Alcon Research
Cataract
Clinical Investigation of AcrySof® IQ PanOptix™ IOL Model TFNT00
The purpose of this clinical study is to compare the visual outcomes of the AcrySof IQ PanOptix Multifocal Intraocular Lens (IOL) Model TFNT00 against that of a monofocal lens, the AcrySof Monofocal IOL Model SN60AT, in order to…
- Trial name
- NCT03280108
- Testing
- AcrySof IQ PanOptix Multifocal IOL, AcrySof Monofocal IOL
- Where
- 12 sites in United States
- Volunteers
- 250 people
- Sponsor
- Alcon Research
Cataract
Clinical Investigation of the Clareon® Intraocular Lens (IOL)
The objective of this study is to compare visual acuity and adverse event outcomes from the Clareon intraocular lens (IOL) to historical safety and performance endpoint (SPE) rates.
- Trial name
- NCT03170154
- Testing
- Clareon aspheric hydrophobic acrylic monofocal IOL
- Where
- 16 sites in United States
- Volunteers
- 376 people
- Sponsor
- Alcon Research
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of a Trifocal IOL
This study is a prospective, multicenter, randomized, double masked confirmatory trial comparing an investigational trifocal intraocular lens (IOL) and a commercially available monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT04176965
- Testing
- FINEVISION HP IOL, Alcon AcrySof SN60AT
- Where
- 20 sites in United States
- Volunteers
- 539 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Clinical Investigation of the AcrySof® IQ PanOptix™ IOL
The purpose of this study is to evaluate the effectiveness and safety of the AcrySof® IQ PanOptix™ Intraocular Lens (IOL) Model TFNT00 when implanted to replace the natural lens following cataract removal.
- Trial name
- NCT03090256
- Testing
- AcrySof® IQ PanOptix™ IOL
- Where
- 2 sites in Japan
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Cataract
Clinical Evaluation of the One-Piece Tecnis Multifocal Intraocular Lens (IOL)
The purpose of this study is to evaluate near vision of the One-Piece Tecnis Multifocal lens (ZMB00) vs. the One-piece Tecnis monofocal lens (ZCB00)and additionally evaluate general postoperative outcomes of the One-Piece Tecnis…
- Trial name
- NCT01210807
- Testing
- One-Piece Tecnis Multifocal IOL, One-Piece Tecnis monofocal IOL, Model ZCB00
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Refractive Errors
Measurement of Refractive SE Following Implantation of LS313 MF30 IOL
This Study determines the most precise method for measuring post-operative refraction following implantation of the asymmetric multifocal LS-313 MF30 comparing the results of Refraction of the different Autorefractor Keratometers…
- Trial name
- NCT03292614
- Testing
- Measurements of the postoperative refraction
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Cataract
Clinical Investigation of a New Intraocular Lens
The purpose of this clinical trial is to evaluate the safety and effectiveness of the TECNIS Symfony Extended Range of Vision IOL.
- Trial name
- NCT02203721
- Testing
- TECNIS Symfony Extended Range of Vision IOL, Model ZXR00, TECNIS Monofocal IOL, Model ZCB00
- Where
- 15 sites in United States
- Volunteers
- 324 people
- Sponsor
- Abbott Medical Optics
Cataract, Corneal Astigmatism
Post-market Study to Obtain Surgeon Feedback on Clinical Outcome in Eyes Implanted With TECNIS Toric II IOL
This is a multicenter, prospective, single-arm, open-label, clinical study of the commercially available TECNIS Toric II, Model ZCU IOL.
- Trial name
- NCT04210232
- Testing
- TECNIS® TORIC II Intraocular Lens (IOL)
- Where
- 12 sites in United States
- Volunteers
- 54 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.