Clinical trials: IMPLANTATION
Implant
Soft and Hard Tissue Changes After Immediate Single-tooth Replacement
A recent systematic review (Lee et al, 2016) reported that placement of a soft tissue graft concurrent with immediate implantation may contribute to the stability of gingival level and the augmentation of soft tissue contour.
- Trial name
- NCT03784430
- Testing
- Immediate dental implant placement, Immediate dental implant placement with CTG
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Ridge Augmentation
Autogenous Bone Ring Versus Split Bone Block for Management of Posterior Atrophic Mandible
Teeth loss in the posterior mandible initiates residual ridge resorption especially in vertical direction, this causes difficulty in implant placement so ridge augmentation must be done either simultaneous with implant placement…
- Trial name
- NCT07140887
- Testing
- Bone Ring, Split Bone block
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Jaw, Edentulous, Partially
Straumann Roxolid Multi-Center Study
The primary objective of this study is to demonstrate non-inferiority of the Straumann Bone Level Ø 3.3 mm NC SLActive Roxolid Implants compared to Straumann Bone Level Ø 4.1 mm RC SLActive Roxolid Implants based on mean crestal…
- Trial name
- NCT01842958
- Testing
- Straumann Bone Level Implants, 4.1 mm implant diameter, Straumann Bone Level Implants, 3.3 mm implant diameter
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut Straumann AG
Patients Implanted With Monofocal Intraocular Lens
Prospective Evaluation of Near and Intermediate Visual Outcomes With Monofocal Intraocular Lenses: The Mast Study
The purpose of this study is to evaluate the near and intermediate visual outcomes of patients who have undergone routine cataract surgery (removal of cloudy crystalline lens) with phacoemulsification (the break-up and removal of…
- Trial name
- NCT01191515
- Testing
- Monofocal Intraocular Lenses
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Dental Implants
Dynamic Navigation vs. the Freehand Method
The purpose of the study is to evaluate in novice surgeons the accuracy of the X-Guide® navigation system (X-Guide®, X-Nav Technologies®, Pennsylvania, USA) in implant placement compared to freehand implant placement.
- Trial name
- NCT06028750
- Testing
- Dynamic Computer Assisted Surgery, Freehand
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Atrophy of Edentulous Alveolar Ridge
Evaluation of Dental Implant Placement in the Sloped Alveolar Ridge
The aim of this study was to investigate the therapeutic effect of sloped dental implants. It can reduce the need of osteoectomy, reduce discomfort of procedures, and is easier for maintenance.
- Trial name
- NCT03543618
- Testing
- Sloped, Control
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Nasolabial Fold Wrinkles
DL6049 vs CosmoPlast in the Treatment of Nasolabial Fold Wrinkles
This study is being undertaken to: evaluate the degree of correction attainable with DL6049 (injectable poly-L-lactic acid)compared to a commercially available CosmoPlast™ Collagen Implant in the treatment of dermal nasolabial…
- Trial name
- NCT00444210
- Testing
- DL6049 (injectable poly-L-lactic acid)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Bausch Health Americas, Inc.
Recurrent Implantation Failure, Infertility
Comparing FET Guided by ERA Vs Standard Timing in Patients with Recurrent Implantation Failure
The pregnancy rate of in vitro fertilisation (IVF) remains around 35% per transfer. Women who are not pregnant following several embryo transfers are regarded as having recurrent implantation failure (RIF), with one of the causes…
- Trial name
- NCT06762626
- Testing
- Frozen embryo transfer according to endometrial receptivity analysis result
- Where
- China
- Volunteers
- 734 people
- Sponsor
- The University of Hong Kong
Dental Implant Bone Loss
A Randomized Controlled Clinical Trial to Assess Crestal Bone Remodeling of Four Different Implant Designs
This randomized controlled trial aimed to assess the effect of the implant neck design (microthreaded vs. non-microthreaded) as well as the type of abutment connection (internal conical vs.
- Trial name
- NCT06821308
- Testing
- Implant placement
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Ghent
Platelet-rich Fibrin, Simvastatin
Effect of Local Application of Platelet-rich Fibrin Scaffold Loaded With Simvastatin on Peri-implant Bone Changes
ACKGROUND: Simvastatin (SIM), a pharmacological drug used for hypercholesterolemia, has been found to have pleotropic effects on bones. Simvastatin together with the appropriate carrier may decrease bone loss around implants.
- Trial name
- NCT05008068
- Testing
- Simvastatin
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Heart Failure, LVAD
The Left Ventricular Assist Device (LVAD) Off or On Pump Implantation Study
The purpose of this study is to compare adverse events after off-pump LVAD surgery or on-pump LVAD surgery.
- Trial name
- LVAD-ON-OFF (NCT04219618)
- Testing
- Off-Pump, On-Pump
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The University of Texas Health Science Center, Houston
Aneuploidy, Chromosome Abnormality
RCT Study to Validate niPGT-A Clinical Benefit.
Chromosomal aneuploidies are linked with spontaneous miscarriages and abnormal offspring in human pregnancies. In addition, some types of aneuploidies are reported to prevent implantation.
- Conditions
- Aneuploidy, Chromosome Abnormality, Infertility
- Trial name
- niPGT-A_RCT (NCT04000152)
- Testing
- niPGT-A, Morphology criteria
- Where
- 8 sites in Argentina, Brazil and 3 more
- Volunteers
- 296 people
- Sponsor
- Igenomix
Aortic Valve Stenosis, Malignancy
Outcomes of Transcatheter Aortic Valve Implantation in Oncology Patients With Severe Aortic Stenosis
As for today, transcatheter aortic valve implantation (TAVI) is indicated only in symptomatic patients with severe aortic stenosis (AS) at high surgical risk.
- Trial name
- TOP-AS (NCT03181997)
- Testing
- Native aortic valve, Transcatheter aortic valve implantation (TAVI)
- Where
- Israel
- Volunteers
- 168 people
- Sponsor
- Rabin Medical Center
Hallux Valgus
Safety, Tolerability and Efficacy of HAVAI, for Correction of Inter-metatarsal Angle
A non-inferiority study to demonstrate efficacy of the HAVAI minimally invasive device compared to standard of surgical care 1st metatarsal osteotomy (SSOC)
- Trial name
- NCT02831868
- Testing
- HAVAI
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- Rabin Medical Center
Peri-Implantitis, Peri-implant Mucositis
Peri-implant Conditions Mimic Periodontal Conditions
Except for patients with referred clinical bruxism and uncontrolled medical conditions, the study included 123 implants with implanted fixed prostheses that had lasted at least six months after functional prosthetic loading.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Peri-implant Health, Periodontitis
- Trial name
- NCT06128850
- Testing
- disease
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Diabetes Mellitus, Type 2, Implant Complication
Posterior Narrow Diameter Implants in Hyperglycemic and Normo-glycemic Patients
The aim of the present study was to compare the initial healing and long term performance of narrow diameter implants in patients with uncontrolled Diabetes mellitus type 2 (T2DM) and healthy individuals.
- Trial name
- NCT04630691
- Testing
- Implantation
- Volunteers
- 35 people
- Sponsor
- University of Witten/Herdecke
TAVI(Transcatheter Aortic Valve Implantation)
ROTAO 1 - Feasibility and Safety of the TAVIPILOT Tele-operated Robot During Transcatheter Aortic Valve Replacement (TAVR/TAVI)
The TAVIPILOT tele-operated robot by Caranx Medical is an advanced intraoperative robotic assistance system designed to enhance the precision of transcatheter aortic valve positioning during TAVR.
- Trial name
- NCT07152574
- Testing
- TAVR using a tele-operated Robot
- Volunteers
- 10 people
- Sponsor
- Caranx Medical
Spinal Tuberculosis, Mesenchymal Stem Cell
Effectivity of Mesenchymal Stem Cell on Vertebral Bone Defect Due to Mycobaterium Tuberculosis Infection
This study evaluates the effectiveness of locally implantation of mesenchymal stem cell on vertebral bone defects due to infection of mycobacterium tuberculosis.
- Trial name
- NCT04493918
- Testing
- Mesenchymal Stem cell + Nacl 0.9%, NaCl 0.9%
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Ahmad Jabir Rahyussalim
Repeated Implantation Failure
Intrauterine Injection of Human Chorionic Gonadotrophin and Pregnancy Rate in ICSI
Despite recent advances in clinical and laboratory techniques of Assisted Reproductive Technology (ART), the pregnancy rate remains around 30% per cycle.
- Trial name
- NCT03445910
- Testing
- Human chorionic gonadotropin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Dental Implant Macrodesign, Dental Implant Surface Treatment
Effect of Implant Macro-Design and Surface Treatment on Insertion Torque and Early Implant Stability Quotient (ISQ)
This prospective, randomized pilot clinical trial will evaluate the effect of dental implant macro-design and surface treatment on insertion torque values (ITV) and early implant stability quotient (ISQ) trajectories in healed…
- Conditions
- Dental Implant Macrodesign, Dental Implant Surface Treatment, Dental Implant Primary Stability, Dental Implant Secondary Stability
- Trial name
- NCT07744776
- Testing
- Chairside implant surface treatment with Plasma X Motion device, SLA implant surface, Straumann BLT implant macro design
- Where
- Lithuania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dantu implantologijos centras
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