Clinical trials: ILM Peeling
Macular Hole Surgery, ILM Peeling
Comparison Between Outcomes of Closure of Idiopathic Macular Hole Using Autologus Tenon Capsule Graft and Internal Limiting Membrane Flap Techniques (Pilot Study)
The aim of this study is to compare the functional visual outcomes, anatomical closure rate and macular perfusion changes assessed by OCT and OCTA after surgical repair of macular hole using Tenon capsule graft versus ILM flap.
- Conditions
- Macular Hole Surgery, ILM Peeling, Tenon Capsule, ILM Flap
- Trial name
- NCT07633457
- Testing
- vitrectomy under topical anesthesia [Proparacaine HCL (Alcaine®)]
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Diabetic Retinopathy, Macular Edema
ILM Peeling in PDR Patients Undergoing PPV for VH
Subjects undergoing ILM peeling during vitrectomy will have better visual acuity and lower rates of DME to control subjects
- Trial name
- NCT03660371
- Testing
- PPV/MP, PPV without MP
- Where
- Mexico
- Volunteers
- 258 people
- Sponsor
- Rush Eye Associates
Diabetes Mellitus
Fovea Sparing ILM Peeling in Diabetic Patients
The goal of this clinical trial is to compare between foveal sparing ILM peeling and total ILM peeling in diabetic patients (both type 1 and II) with proliferative diabetic retinopathy (PDR) indicated for pars plana vitrectomy…
- Trial name
- NCT07271719
- Testing
- Pars plana vitrectomy (PPV) with fovea sparing ILM peeling., PPV with total ILM peeling
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- David Nashaat Shafik Fahmy
Full Thickness Macular Hole
Foveal Sparing ILM Peeling With ILM Flap Transposition
Foveal sparing internal limiting membrane (ILM) peeling with ILM flap transposition over the macular hole combines the benefits of foveal sparing ILM peeling with ILM flap techniques.
- Trial name
- NCT05897671
- Testing
- retrospective data analysis
- Where
- Austria
- Volunteers
- 42 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Stage 2 or 3 Full Thickness Macular Hole
Full Thickness Macular Hole and Internal Limiting Membrane Peeling Study
A macular hole is a fairly common problem in the retina and is an important cause of loss of central vision. The aim of this study is to determine whether, in patients with a stage 2 or 3 full thickness macular hole (FTMH)…
- Trial name
- FILMS (NCT00286507)
- Testing
- Vitrectomy, post hyaloid detachment and gas injection with or without ILM peel.
- Where
- 9 sites in Ireland, United Kingdom
- Volunteers
- 141 people
- Sponsor
- University of Aberdeen
Epiretinal Membrane
Evaluation of the "Grasp Site" After Peeling of Epiretinal Membranes
The goal of this study is to compare the novel ILM sharkskin forceps with a conventional ILM forceps utilizing iOCT assistance during surgery at this "grasp site". The main questions it aims to answer are: 1.
- Trial name
- NCT06753539
- Testing
- ILM forceps - membrane grasping
- Where
- Austria
- Volunteers
- 58 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Macular Holes
Macular Micro Vascular Changes Following Macular Hole Repair : Optical Coherence Tomography Angiography Study
The goal of this prospective interventional study is to to compare the micro vascular and structural changes between surgery with and without ILM flap to repair macular hole.
- Trial name
- NCT06233500
- Testing
- pars plana vitrectomy
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Fayoum University
Macular Holes
ILM Flap Transposition Versus ILM Peeling for Macular Holes: a Pilot Study
Patients with macular hole <400µm will be randomized for ILM flap Transposition and ILM Peeling for surgical repair of macular holes
- Trial name
- NCT03646695
- Testing
- ILM flap transposition, ILM peeling
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Epiretinal Membrane, Macular Pucker
EpiRetinal Membrane Peeling and Internal Limiting Membrane
To study and compare visual acuity in patients undergoing removal of the epiretinal membrane with and without the removal of the internal limiting membrane at baseline versus 6 month.
- Conditions
- Epiretinal Membrane, Macular Pucker, Internal Limiting Membrane
- Trial name
- ERMP&ILM (NCT04802265)
- Testing
- Epiretinal membrane surgery
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Clermont-Ferrand
Idiopathic Epimacular Membrane
Prospective, Single-blind Study Assessing the Benefit/Risk Ratio of Internal Limiting Membrane (ILM) Peeling During Epimacular Membrane (EMM) Surgery (Peeling)
The epimacular membrane (EMM) is a degenerative condition associated with age, with a variable impact on vision. Treatment is surgery based and consists of a vitrectomy followed by a peeling of the epimacular membrane using a…
- Trial name
- Peeling (NCT02146144)
- Testing
- ILM Peeling
- Where
- 6 sites in France
- Volunteers
- 213 people
- Sponsor
- Nantes University Hospital
Macular Hole
Effects of Different Area of Internal Limiting Membrane Peeling (ILM) Peeling on Anatomical Outcomes in Macular Hole Surgery
The purpose of this study is to determine the effects of two different internal limiting membrane (ILM) peeling area on anatomical closure outcomes after macular hole surgery measured by optical coherence tomography (OCT).
- Trial name
- NCT02930369
- Testing
- ILM peeling surgery
- Volunteers
- 128 people
- Sponsor
- Peking University People's Hospital
Proliferative Vitreoretinopathy
Outcomes of Extensive Brilliant Blue G-Assisted Internal Limiting Membrane Peeling in Proliferative Vitreoretinopathy
The aim of this study is to report outcomes of pars plana vitrectomy (PPV) in retinal detachment (RD) accompanied with proliferative vitreoretinopathy (PVR) after extensive Brilliant Blue G-Assisted internal limiting membrane…
- Trial name
- ILM (NCT04490876)
- Testing
- 3D Pars Plana Vitrectomy associated with Extensive Brilliant Blue G-Assisted ILM Peeling Method
- Where
- Argentina
- Volunteers
- 14 people
- Sponsor
- Centro Oftalmológico Dr Charles
Retinal Detachment
Impact of ILM Peeling in RRD/ I-Peel
Retinal detachment is associated with a substantial risk of re-detachment in 10-20% and to the formation of secondary epiretinal membranes in up to 15%.
- Trial name
- I-Peel (NCT04767555)
- Testing
- ILM (inner limiting membrane) peeling
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Berner Augenklinik
Epiretinal Membrane of Both Eyes
Optical Coherence Tomography Angiography (OCTA) Changes in Patients With Epiretinal Membranes (ERM) With and Without Peeling of the Internal Limiting Membrane (ILM)
Main objective The objective is to compare two surgical options in vitrectomies for epiretinal membranes using parameters of optical coherence tomography angiography.
- Trial name
- NCT05287009
- Testing
- ILM nonpeeling, ILM peeling
- Where
- Austria
- Volunteers
- 51 people
- Sponsor
- Medical University of Graz
Diabetic Macular Edema, Pars Plana Vitrectomy
Microinvasive Pars Plana Vitrectomy Combined ILM Peeling Versus Anti-VEGF Intravitreal Injection for Treatment-naïve Diabetic Macular Edema
Diabetic macular edema (DME) is the main cause of vision loss in patients with diabetes. At present, anti-vascular endothelial growth factor (VEGF) intravitreal injection is the first-line therapy for DME, nevertheless, some…
- Conditions
- Diabetic Macular Edema, Pars Plana Vitrectomy, Conbercept
- Trial name
- NCT05728476
- Testing
- Vitrectomy combined with ILM peeling, Conbercept intravitreal injection
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Tianjin Medical University Eye Hospital
Epimacular Membrane
Outcomes Based on the Pre-operative Integrity of IS/OS Junction in Idiopathic Epimacular Membrane Surgery
The aim of this study is to evaluate whether the pre-operative integrity or not of the inner segment (IS) and outer segment (OS) photoreceptoral junction may influence the post-operative visual acuity, the macular morphology…
- Trial name
- NCT04158791
- Testing
- pars plana vitrectomy with epimacular membrane removal and internal limiting membrane peeling
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Diffuse Diabetic Macular Edema
Triple Therapy for Diffuse Diabetic Macular Edema
The purpose of this study is to evaluate the safety end efficacy of combined phakoemulsification and vitrectomy with retinal endophotocoagulation and intraoperative use of bevacizumab in patients with diffuse diabetic macular…
- Trial name
- TTDDME (NCT01218750)
- Testing
- Triple therapy for diffuse diabetic macular edema
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Military Institute od Medicine National Research Institute
Diabetic Vitreous Hemorrhage, Tractional Retinal Detachment
Assessment of Retinal Vascular Changes With and Without ILM Peeling in Diabetic Vitrectomy Using OCT-A.
Tractional retinal detachment (TRD) that involves the macula and non-clearing vitreous hemorrhage are the main causes of permanent vision loss in patients with diabetic retinopathy and requires prompt surgical intervention.
- Trial name
- NCT05739539
- Testing
- optical coherence tomography angiography, spectral domain optical coherence tomography
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kasr El Aini Hospital
Epiretinal Membrane, Internal Limiting Membrane Wrinkling
Fovea ERM After Fovea-sparing ILM Peeling
To report cases who had received previous fovea-sparing internal limiting peeling membrane and developed secondary fovea epiretinal membrane contraction
- Trial name
- NCT04445142
- Testing
- fovea-sparing internal limiting membrane peeling
- Where
- Taiwan
- Volunteers
- 3 people
- Sponsor
- Changhua Christian Hospital
Efficacy, Safety
Effect of PPV+ILM Peeling +/- Subretinal Injection of Ringer Lactate in Management of Nontractional Refractory DME
To evaluate the efficacy and safety of combined pars plana vitrectomy and planned foveal detachment through subretinal injection of ringer's solution in patients with non-tractional refractory diabetic macular edema.
- Trial name
- NCT06271473
- Testing
- vitrectomy + ILM peeling +/- planned foveal detachment via subretinal injection of ringer's solution.
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University