Clinical trials: ICU Survivors
Intensive Care (ICU) Myopathy
Biomechanical Properties in Intensive Care Unit (ICU) Survivors 12-month After Discharge
Intensive care unit (ICU) admission is associated with muscle weakness and ICU survivors report persevering limitation of physical capacity for years after discharge.
- Trial name
- NCT01364714
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Critical Illness, Delirium
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
Up to 25% of intensive care unit (ICU) survivors experience cognitive impairment comparable in severity to mild Alzheimer's disease and related dementias after hospital discharge.
- Conditions
- Critical Illness, Delirium, Cognitive Impairment, Cognitive Decline
- Trial name
- SLEEP-COG (NCT06411561)
- Testing
- SLEEP + COG, COG, SLEEP
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Post-Intensive Care Syndrome, Depressive Symptoms
Pilot Study of a Multidisciplinary Intervention in ICU Survivors at Risk for Psychological or Physical Morbidity
Pilot study of the feasibility and utility of an early, in-hospital multidisciplinary intervention in ICU survivors at risk for psychological and physical problems post-ICU stay
- Conditions
- Post-Intensive Care Syndrome, Depressive Symptoms, Anxiety, Physical Disability
- Trial name
- IMPRESS (NCT06118606)
- Testing
- Case-manager led multidisciplinary follow-up after intensive care
- Where
- 2 sites in Sweden
- Volunteers
- 41 people
- Sponsor
- Region Stockholm
Post-Intensive Care Syndrome (PICS), Symptom Burden
Post-Intensive Care Syndrome and Associated Symptom Burden Among Danish ICU Survivors
The study aims to estimate the prevalence of post-intensive care syndrome (PICS) 12 months after ICU admission among adult ICU survivors in Denmark and to describe how this prevalence is distributed across the physical…
- Conditions
- Post-Intensive Care Syndrome (PICS), Symptom Burden, Intensive Care Unit (ICU) Patients
- Trial name
- PICAS-DK (NCT07373561)
- Volunteers
- 800 people
- Sponsor
- Zealand University Hospital
Critical Illness, Major Abdominal Surgeries
Metabolic and Muscle Profile in ICU Survivors
More and more patients survive a critical illness requiring admission to the intensive care unit, but they may be left with sequelae that are independent of the initial pathology.
- Trial name
- IM3SI (NCT07329530)
- Testing
- Inflammation markers, Blood nucleosomes, Erythrocyte membrane fatty acid content
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Anne-Françoise Rousseau
Acute Respiratory Failure, Caregiving Stress
Investigating Dyadic Expectations About ARF Survivorship (IDEAS)
The purpose of this observational study is to understand how adults who survive acute respiratory failure (ARF) and the people (usually family) who support ARF survivors after returning home think about the first 6 months of…
- Conditions
- Acute Respiratory Failure, Caregiving Stress, Mental Health Issue
- Trial name
- IDEAS (NCT06401239)
- Testing
- Dyadic expectations about the ARF survivor's perceived health 6 months after hospital discharge, Self-efficacy, Concordant expectations/shared appraisal of ARF survivor's health 6 months after hospital discharge
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Johns Hopkins University
ICU Survivors
Integrated Recovery Program for Critical Illness
This study aims to investigate the effects of the Integrated Critical Illness Aftercare and Recovery Enhancement (I-CARE) program on reducing healthcare burden and improving functional outcomes in ICU survivors.
- Trial name
- iCARE (NCT06997822)
- Testing
- LINE Bot-Based Remote Care Combined with In-Person Post-ICU Clinic
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- National Taiwan University Hospital
Neurocognitive Disorders
Clinical Translational Science Institute (CTSI) Brain HQ Modules vs. Active Controls for Elderly Survivors of ICU
The purpose of this project is to test whether an online cognitive rehabilitation program or online thinking exercises helps improve memory and thinking in elderly patients who survive a severe infection.
- Trial name
- NCT04081090
- Testing
- Brain HQ Cognitive Modules
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Medical College of Wisconsin
Neurocognitive Dysfunction
Neuro-cognitive Function 1 Year Post ICU Discharge Among VV ECMO Survivors
In the past three years, in the general intensive care unit in Meir medical center, 25 patients were treated with ECMO, of which two patients were treated with VA ECMO and the rest with VV ECMO.
- Trial name
- NCT06224088
- Testing
- VV ECMO
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Meir Medical Center
Acute Respiratory Failure, Post-Intensive Care Syndrome
Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors
The m-CCRP randomized controlled trial will evaluate the efficacy of a collaborative critical care recovery program from acute respiratory failure (ARF) survivors in accomplishing the Institute of Healthcare Improvement's triple…
- Trial name
- m-CCRP (NCT03053245)
- Testing
- Mobile Critical Care Program, Attention Control
- Where
- 3 sites in United States
- Volunteers
- 503 people
- Sponsor
- Indiana University
Post Intensive Care Syndrome, ICU Survivors
The Post Intensive Care Syndrome Follow-up and Management Study: The ICU Recovery Answers Project
Critically ill survivors develop mental health, cognition, and mobility sequelae known as Post-Intensive Care Syndrome (PICS). Clinically significant symptoms of post-traumatic stress, depression, anxiety, and cognitive…
- Conditions
- Post Intensive Care Syndrome, ICU Survivors, ICU Families
- Trial name
- ICURA (NCT06504979)
- Testing
- Telehealth follow-up of post-intensive care syndrome
- Where
- Spain
- Volunteers
- 360 people
- Sponsor
- Corporacion Parc Tauli
Critical Illness, Heart Failure
Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress
Serious acute heart and lung illnesses like heart failure, severe COVID, and sepsis often leave survivors struggling not only physically, but also with lasting depression, anxiety, and stress.
- Conditions
- Critical Illness, Heart Failure, Sepsis, Ards
- Trial name
- Lift 3 (NCT07634419)
- Testing
- Lift mobile mindfulness, Enlighten Recovery education program
- Where
- 3 sites in United States
- Volunteers
- 450 people
- Sponsor
- Duke University
Functionally-Impaired Elderly, Caregivers
Impact on Family or Care-givers of Very Old ICU-survivors, Trajectories and 6 Months' Outcome in the Very Old.
It is known from extensive documentation that second victims in critical illness often are the care givers of the patients: family, friends or other persons.
- Conditions
- Functionally-Impaired Elderly, Caregivers, PTSD, Depression, Anxiety
- Trial name
- VIP2 (NCT03138278)
- Testing
- Telephone support on demand
- Sponsor
- University of Bergen
Physical Disability, Depression
Prognostication of Need for Rehabilitation and Special Support in ICU Survivors
Title: PROGnostication of need for REhabilitation and Special Support after Intensive Care Unit Stay - a multinational, observational study Objectives: 1.
- Conditions
- Physical Disability, Depression, Posttraumatic Stress Disorder, Anxiety
- Trial name
- PROGRESS-ICU (NCT02679157)
- Where
- 10 sites in Denmark, Netherlands and 1 more
- Volunteers
- 573 people
- Sponsor
- Karolinska University Hospital
Ischemic Stroke, Post Intensive Care Unit Syndrome
Cytoflavin in the Rehabilitation of Post-intensive Care Syndrome in Stroke Survivors
Objective - to assess the effect of Cytoflavin® and its tolerability within the integrated program of rehabilitation of patients who underwent ischemic stroke
- Trial name
- NCT04194229
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Sepsis
PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors
The purpose of this study is to define the natural history and causes of chronic critical illness (CCI) in surgical intensive care patients who have had sepsis.
- Trial name
- PICS (NCT02276417)
- Testing
- Blood collection, Urine collection, Bioimpedance Analysis
- Where
- United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- University of Florida
Critical Illness, Intensive Care Unit Delirium
Bringing to Light the Risk Factors And Incidence of Neuropsychological Dysfunction in ICU Survivors, 2nd Study
This BRAIN-ICU-2 study [Bringing to light the Risk factors And Incidence of Neuropsychological dysfunction (dementia) in ICU Survivors, 2nd Study] is in direct response to PAR-17-038 and will determine ICU patients' main paths to…
- Trial name
- BRAIN-2 (NCT04305600)
- Where
- 2 sites in United States
- Volunteers
- 567 people
- Sponsor
- Vanderbilt University Medical Center
Covid19
COVID-19 Survivorship Registry
COVID-19 is associated with acute pulmonary and cardiac injury. To better understand the degree and severity of cardiopulmonary injury as well as short and long-term sequelae of COVID-19 infection, this study will perform…
- Trial name
- NCT04527315
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Post Intensive Care Syndrome (PICS)
Surviving the Pediatric Intensive Care Unit (PICU)
Improvement in pediatric intensive care unit (PICU) supportive care has led to improvement in clinical outcomes and decreased mortality in pediatric critical illness.
- Trial name
- NCT06812130
- Testing
- This is a non-interventional study.
- Where
- 2 sites in Singapore
- Volunteers
- 404 people
- Sponsor
- KK Women's and Children's Hospital
Circadian Dysregulation, Sleep Fragmentation
Compromised Sleep and Circadian Health After Critical Illness: From Diagnosis to Prediction (CHRONOCRIT)
The intensive care unit (ICU) is recognizably detrimental to sleep and circadian health, and critical survivors frequently report the presence of alterations in this regard after hospital discharge.
- Trial name
- CHRONOCRIT (NCT05995132)
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida