Clinical trials: ICU
Weaning Failure
Interest of High Flow Nasal Cannula Oxygen Therapy in Pediatric Intensive Care Unit
monocentric randomized controlled trial starting from Mars 2017, recruitment is still ongoing. Patients aged between 0-45 days needing mechanical ventilation (MV) with tracheal intubation were included random assignation in two…
- Trial name
- NCT03505814
- Testing
- High Flow Nasal Cannula Oxygen therapy (OPTIFLOW®), Conventional oxygen therapy
- Where
- Tunisia
- Volunteers
- 126 people
- Sponsor
- Hôpital d'enfants Béchir-Hamza
Artificial Intelligence, Qualitative Research
Qualitative Research Among Physicians and Junior Doctors Into the Preconditions for Implementing a CDSS Based on AI in the ICU
The goal of this study is to explore the different attitudes and preconditions of potential end-users (doctors \& physicians in training) required to achieve successful clinical implementation of models based on artificial…
- Conditions
- Artificial Intelligence, Qualitative Research, Decision Support Systems, Clinical
- Trial name
- KATRINA (NCT05303025)
- Testing
- Survey, Semi-structured group discussion
- Where
- 3 sites in Belgium
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Ghent
Antibiotic Resistant Infection
Effectiveness of Chlorhexidine Wipe for Prevention of Multidrug-resistant Organisms in Intensive Care Unit Patients
The purpose of this study is to determine 2% chlorhexidine wipes are effective in preventing of colonization of multi-drug resistant bacteria in intensive care unit patients.
- Trial name
- NCT01989416
- Testing
- 2% chlorhexidine wipe, Soap
- Where
- Thailand
- Volunteers
- 481 people
- Sponsor
- Mahidol University
Microbial Colonization, Ventilator Associated Pneumonia
Frequent Standardized Oral Care to Improve Health Outcomes in Premature Infants in the Neonatal Intensive Care Unit
Premature very low birth weight (VLBW) infants are susceptible to complications related to infrequent and non-standardized oral care.
- Trial name
- NCT05167318
- Testing
- frequent standardized oral care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Florida
Surgery--Complications
Association of the Arteriovenous Difference in Carbon Dioxide and Its Relation to the Difference in Arteriovenous Oxygen Content With the Occurrence of Postoperative Complication
Intra-operative hemodynamic management in high-risk surgery is a priority for the anesthesiologist. The current strategy is based on the continuous measurement of cardiac output and its maximization by vascular filling has many…
- Trial name
- CARBODAV (NCT03914976)
- Testing
- patient having to undergo a high risk programmed digestive surgery
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon
ARDS, Human, Respiratory Failure
Driving Pressure and Mortality: in the Pediatric Intensive Care Unit (PICU)
Respiratory failure is one of the most common causes of both hospitalization and mortality in patients in the pediatric intensive care unit (PICU).
- Trial name
- NCT04419376
- Testing
- driving pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Septic Shock, Fluid Therapy
Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic Shock
The purpose of the study is to determine if a protocol that assesses patients' daily fluid intake and output can decrease the overall amount of fluid patients receive during the first five days in the ICU.
- Conditions
- Septic Shock, Fluid Therapy, Hypotension
- Trial name
- NCT02473718
- Testing
- Fluid minimization protocol, Ultrasound
- Volunteers
- 82 people
- Sponsor
- Washington University School of Medicine
Sepsis, Nutrition
Personalized Nutritional Formula for ICU Patients: A Study on Prognosis and Multidimensional Health Markers
This study aims to evaluate the effects of an individualized enteral nutrition formula on clinical outcomes in critically ill adult patients in the intensive care unit (ICU).
- Conditions
- Sepsis, Nutrition, Gut -Microbiota
- Trial name
- NCT07755033
- Testing
- Individualized Enteral Nutrition Formula, Standard Enteral Nutrition Formula
- Volunteers
- 1,200 people
- Sponsor
- Chinese Medical Association
Critically Ill
Link Between Plasma Citrulline and Lipopolysaccharide Concentrations in the Critically Ill
In critically ill patients, the small bowel permeability is increased, leading to bacterial translocation, and systemic inflammatory response syndrome. Plasma citrulline is a validated biomarker of functional enterocyte mass.
- Trial name
- CITRANS (NCT02902276)
- Testing
- additional blood sample
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Sleep Disturbance, Fatigue
The Effect Of Progressıve Relaxatıon Exercıses
This study was conducted to evaluate the effect of progressive relaxation exercises applied to nurses working in the intensive care unit three times a week for 1 month on sleep quality and severity of fatigue.
- Trial name
- NCT04959214
- Testing
- progressive relaxation egzersize
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seren
Tongue Edema, Tongue Enlarged
Tongue Edema Caused by Intubation Tube in Intensive Care Unit Patients
Tongue edema (TE) is an enlargement of the tongue that can be noticed with the naked eye and protrudes from the mouth. Endotracheal intubation tube, which can exert high pressure on the tongue for a long time, may cause TE.
- Conditions
- Tongue Edema, Tongue Enlarged, Mechanical Ventilation Complication, Intubation Complication
- Trial name
- NCT05249738
- Testing
- Measuring tongue cross-sectional area by submental ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Selcuk University
Subarachnoid Hemorrhage, Intracranial Hemorrhage
Enteral Nutrition and Glycemic Variability Neurological Intensive Care Unit Study
Primary Objective: To determine the effects of a diabetes specific enteral formula compared to a standard formula supplemented with protein (isocaloric and isonitrogenous) on the mean blood glucose and glycemic variability in a…
- Conditions
- Subarachnoid Hemorrhage, Intracranial Hemorrhage, Ischemic Strokes, Subdural Hematoma
- Trial name
- ANUS1014 (NCT01463878)
- Testing
- Glycerna, Jevity - Control Diet
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Eastern Virginia Medical School
Weaning From Mechanical Ventilation
Post Extubation Chest Physiotherapy in ICU
The purpose of this study is to examine the efficacy of chest physiotheray treatment in preventing pulmonary complications and weaning faliure, in extubated critically ill patients.
- Trial name
- NCT01967108
- Testing
- chest physiotherapy
- Where
- Israel
- Volunteers
- 65 people
- Sponsor
- Rambam Health Care Campus
Intensive Care Unit Delirium
Prevention of Delirium in ICU Using Multimodal Interventions
This study was designed to evaluate the impact of non-pharmacological multimodal interventions including ongoing orientation, sensory correction, setting of familiar circumstance and promotion of sleep enviromnet for prevention…
- Trial name
- NCT05950958
- Testing
- Multimodal therapy for prevention of delirium
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Seoul National University Hospital
Critical Illness, Muscle Atrophy
Skeletal Muscle Wasting in ICU Patients
Muscle wasting occurs rapidly in critically ill patients and impacts both short and long term outcomes. Altered protein metabolism drives muscle loss in ICU patients, with muscle protein breakdown exceeding muscle protein…
- Trial name
- IC-MPS (NCT06234826)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Frank Vandenabeele
Mechanical Ventilation Complication
Reduce Pediatric Sedation to Reduce Mechanical Ventilation Complication in ICU
Mechanical ventilation is a common procedure used in pediatric intensive care units (ICU). Its use requires almost always the establishment of a sedation.
- Trial name
- PEDIASED (NCT02040168)
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Nantes University Hospital
Neurologic Disorder
The Effect of Proprioceptive Neuromuscular Facilitation on Haemodynamic Responses in a Neurological Intensive Care
Although there are studies examining the effect of actively performed PNF exercises on haemodynamic responses in intensive care patients and healthy individuals, there are no studies investigating their effect on circulation and…
- Trial name
- NCT07524790
- Testing
- Proprioceptive Neuromuscular Facilitation Exercises, Passive Range of Motion Exercises
- Volunteers
- 24 people
- Sponsor
- Abant Izzet Baysal University
Cardiac Output, Low
Hemodynamic Parameters Assessment; Invasive Versus Noninvasive
The study aims at evaluating effectiveness of noninvasive cardiometry in assessment of cardiac parameters in critically ill patients in respiratory ICU in comparison to invasive methods as indirect fick's and thermodilution…
- Trial name
- NCT06198621
- Testing
- cardiometry
- Volunteers
- 75 people
- Sponsor
- Assiut University
Preterm Birth, Premature Birth
Exposure to Plasticisers in the Neonatal Intensive Care Unit
Neonatal intensive care relies on indwelling plastic medical devices fundamental in respiratory support, intravenous catheterization, and nutrition.
- Conditions
- Preterm Birth, Premature Birth, Neurodevelopmental Disorders, Pulmonary Disease
- Trial name
- PLASTIC-NICU (NCT05404815)
- Where
- Belgium
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Preterm Birth, Prematurity
Parent-child Interactions, Child Developmental Health, and Health System Costs at 6 Months Corrected Age
The aim of this novel health services research proposal is to assess the longer-term outcomes, to 6 months corrected age, of an adapted Family Integrated Care (FICare) model of care for moderate and late preterm infants admitted…
- Conditions
- Preterm Birth, Prematurity, Infant,Premature, Infant Development
- Trial name
- NCT03357458
- Testing
- Family Integrated Care
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Calgary
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