Clinical trials: Hysteroscopy
Intrauterine Abnormalities in Infertility
SIGnificance of Routine Hysteroscopy Prior to a First 'in Vitro Fertilization'(IVF) Treatment Cycle
BACKGROUND: Despite the numerous advances in the field of in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI), there still exists a maximum implantation rate per embryo transferred of about 30%.
- Trial name
- inSIGHT (NCT01242852)
- Testing
- Office hysteroscopy (in combination with a 'Saline Infusion Sonography'(SIS))
- Where
- Netherlands
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Intrauterine Adhesions, Chronic Endometritis
Role of Chronic Endometritis in Postoperative Recurrence of Severe Intrauterine Adhesions
This study is to evaluate the prevalence of chronic endometritis (CE) in women with severe intrauterine adhesions and compare recurrence of adhesion in women with and without CE.
- Trial name
- NCT02744807
- Testing
- Chronic endometritis
- Volunteers
- 125 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Hysteroscopy, Cervical Ripening
Significance of Misoprostol-induced Cervical Ripening Prior to Hysteroscopy
The goal of this prospective study is to evaluate the efficacy and safety of misoprostol for cervical ripening prior to hysteroscopy
- Trial name
- NCT06726278
- Testing
- Misoprostol 400mcg Tab
- Where
- Pakistan
- Volunteers
- 539 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Endometrial Polyp, Endometrial Diseases
The Use of Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation
The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety…
- Trial name
- NCT06316206
- Testing
- Ethinylestradiol/Dienogest 0.03mg/2mg
- Where
- 2 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Menorrhagia
Comparison of Two Hysteroscopy Approaches
This randomized clinical trial compares two methods of diagnostic hysteroscopy: vaginoscopic hysteroscopy vs. traditional method.
- Trial name
- NCT00319410
- Testing
- vaginoscopic hysteroscopy
- Where
- Israel
- Volunteers
- 130 people
- Sponsor
- Wolfson Medical Center
Intrauterine Device Expulsion, Adenomyosis, Endometriosis
Clinical Observation of Hysteroscopy-Assisted Placement of Handmade Frameless GyneFix-LNG-IUS (Retrospective Cohort)
This is a retrospective self-controlled observational study. We evaluated the safety and efficacy of a handmade frameless levonorgestrel-releasing intrauterine system (GyneFix-LNG-IUS) in patients at high risk of IUD expulsion.
- Conditions
- Intrauterine Device Expulsion, Adenomyosis, Endometriosis, Menorrhagia, Dysmenorrhea, Abnormal Uterine Bleeding
- Trial name
- Gyne-LNG-IUS (NCT07518693)
- Testing
- Handmade Frameless GyneFix-LNG-IUS
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Yu Wang
Anesthesia Depth Monitoring, Analgesia Assessment
Target-Controlled Infusion (TCI) Effectiveness in Hysteroscopy
This prospective, randomized, observational study aims to evaluate the perioperative anesthetic efficacy of different Target-Controlled Infusion (TCI) models-specifically Minto, Schnider, and Eleveld pharmacokinetic models-in…
- Conditions
- Anesthesia Depth Monitoring, Analgesia Assessment, Perioperative Safety and Recovery, Target Controlled İnfusion
- Trial name
- NCT07023263
- Testing
- Schnider+ Mİnto, Eleveld
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gazi University
Pain
A Study to Investigate the Analgesic Efficacy of Ibuprofen Alone and Ibuprofen Plus Hyoscine-n- Butyl Bromide in Reducing Pain of Outpatient Hysteroscopy
For outpatient hysteroscopy (OH), it is recommended to take a standard dose of NSAIDs or more hyoscine-n butyl bromide (HBB) an hour prior to the procedure to minimize pain during the first postoperative hour.
- Trial name
- NCT06398054
- Testing
- Ibuprofen 400 mg, Hyoscine N-Butil Bromide
- Volunteers
- 190 people
- Sponsor
- ASST Fatebenefratelli Sacco
Intrauterine Adhesion
Postoperative Intermittent Intrauterine Balloon Dilatation Therapy.
In this prospective, randomized, controlled study, the investigators wish to determine the efficacy of intrauterine balloon (IUB) dilatation in the prevention of adhesion reformation when compared with the conventional management.
- Trial name
- NCT03131596
- Testing
- IUB dilatation therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Subfertility, Infertility
Hysteroscopy Before in Vitro Fertilization - Does it Improve the Outcome?
By randomizing sub-fertile women to either control or office-hysteroscopy in the circle prior to IVF or ICSI (intracytoplasmatic sperm injection ) treatment, we aim to enlighten whether hysteroscopy with endometrial biopsy…
- Trial name
- NCT01743391
- Testing
- Office-hysteroscopy with biopsy
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Septum; Uterus, Infertility, Female
Preterm Delivery After Septum Resection
Uterine septum is the most common congenital uterine malformation. It accounts for approximately 35% of all uterine malformations, while the frequency of uterine malformations in the general fertile population is estimated to be…
- Conditions
- Septum; Uterus, Infertility, Female, Preterm Birth
- Trial name
- PLEASURE-1 (NCT04098289)
- Testing
- Hysteroscopic septum resection, In vitro fertilization
- Volunteers
- 420 people
- Sponsor
- Università degli Studi dell'Insubria
Hysteroscopy
Vaginal Dinoprostone Prior to Diagnostic Office Hysteroscopy in Primarily Infertile Patients
To compare the effectiveness of vaginal dinoprostone with placebo in minimizing the pain experienced by primarily infertile patients during diagnostic office hysteroscopy and to assess the ease of insertion of hysteroscope as…
- Trial name
- NCT04042974
- Testing
- vaginal dinoprostone
- Volunteers
- 100 people
- Sponsor
- Cairo University
Pregnancy Complicated With Intrauterine Adhesion
Comparison of Operative Hysteroscopy and Vacuum Aspiration for Terminating First-trimester Pregnancy With Intrauterine Adhesions
In cases of early pregnancy complicated with intrauterine adhesions (IUAs), termination of pregnancy is prone to incomplete abortion with retained gestational products, failed abortion or uterine perforation due to altered…
- Trial name
- NCT07883057
- Testing
- Vacuum Aspiration Group, Hysteroscopy adhesiolysis combined with vacuum aspiration
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Infertility
Hysterosalpingography and Hysteroscopy in ICSI
unexplained infertility is a rising problem in clinical practice
- Trial name
- NCT04778319
- Testing
- occlusion of tubes, non occlusion of tubes
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aljazeera Hospital
Paracervical Block
Paracervical Block During Office Hysteroscopy
The purpose of this study is to determine the effectiveness of paracervical block for pain relief in office hysteroscopy - particularly with the placement of the Essure device.
- Trial name
- NCT00811187
- Testing
- Lidocaine paracervical block, Normal Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Evaluate Both Technics on Procedure Duration, Characteristics and Perioperative Complications
Evaluation of a Hysteroscopic Morcellator in Hysteroscopic Treatment of Submucosal Fibroids
Hysteroscopic surgery is the gold standard for intra uterine pathology especially fibroma. Limit of this technic is duration of procedure which is correlated to operative complications.
- Trial name
- NCT02406898
- Testing
- morcellator uterine system (MH)Karl Storz, Tuttligen- Germany
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Hysteroscopy
Comparison Between the Intrauterine Lidocaine and Warm Saline Distention Medium for Pain Relief During Office Hysteroscopy
Procedure: The procedure was done in the lithotomy position during the postmenstrual period. We used a 30° angle 2.9 mm rigid hysteroscopy with 3.8 mm diagnostic sheath [TEKNO®, LIGHT XA 180, Germany].
- Trial name
- NCT06946121
- Testing
- Lignocaine, Saline
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Intrauterine Polyp
Darwish Test (Office Hysteroscopic Bubble Suction and Tubal Peristalsis) in Cases of Intrauterine Polyp(s)
Anatomic Fallopian tubal patency and physiologic patency testing are feasible via hystertoscopy. This study aims to test the impact of different types of intrauterine polyp(s) on Darwish test (office hysteroscopic bubble suction…
- Trial name
- NCT04367415
- Testing
- Darwish test for a free endometrial cavity, Darwish test for an endometrial cavity with endometrial polyps
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Woman's Health University Hospital, Egypt
Cervical Priming
Efficacy and Safety Study of the Misoprostol Vaginal Priming Insert (MVPI) Prior to Hysteroscopy
A Phase II, multicenter, double-blind, randomized, placebo-controlled, dose-ranging, study to assess the efficacy and safety of the 100, 200, 400, 800, 1200 and 1600 mcg Misoprostol Vaginal Priming Insert (MVPI) for Women…
- Trial name
- NCT00925938
- Testing
- misoprostol
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Ferring Pharmaceuticals
Abnormal Uterine Bleeding
The Role of TVSG and HS in Determining Endometrial Pathologies
Although hysteroscopy (HS) and transvaginal ultrasonography (TVSG) are methods in the diagnosis of AUB, there is some suspicion about their efficacy.
- Trial name
- NCT03441087
- Testing
- Transvaginal ultrasound, Hysteroscopy
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital