Clinical trials: Hypopigmentation
Vitiligo
PHNA, Efficacy of Tretinoin Cream on Post-phototherapy Hyperpigmentation
A randomized controlled split-face pilot study was planned to investigate the preventive effect of tretinoin 0.05% cream on hyperpigmentation during phototherapy in patients with vitiligo.
- Trial name
- NCT03933774
- Testing
- Tretinoin 0.05% cream
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Vitiligo
Improved Phototherapy in Patients With Vitiligo
Vitiligo is a common acquired depigmentation skin and mucosal disease in dermatology, with or without white hair. Vitiligo with white hair is difficult to treat.
- Trial name
- NCT05836441
- Testing
- Exposure to white patches, Exposure to edge of white patches and normal skin around white patches
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Vitiligo, Treatment
Efficacy of Intralesional Triamcinolone Injection in the Treatment of Vitiligo
A randomized split-body pilot study was planned to confirm efficacy of intralesiona triamcinolone injection in patients with vitiligo
- Conditions
- Vitiligo, Treatment, Intralesional Injection, Corticosteroid
- Trial name
- NCT03365141
- Testing
- Triamcinolone acetonide 0.4mg/cc, Phototherapy (NBUVB or excimer laser), Topical tacrolimus
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- The Catholic University of Korea
Vitiligo
HI-Light Pilot Trial for Vitiligo: Hand Held NB-UVB for Early or Focal Vitiligo at Home
This study is a small pilot randomised controlled trial (RCT) comparing hand-held NB-UVB light devices with placebo devices. These devices will be used by the participants to treat their vitiligo at home for a period of four…
- Trial name
- HI-Light (NCT01478945)
- Testing
- 311 nm NB-UVB light
- Where
- 2 sites in United Kingdom
- Volunteers
- 29 people
- Sponsor
- University of Nottingham
Neck Pain
Effects of MET and Biofeedback Strengthening With and Without Kinesiotaping in Upper Crossed Syndrome
This randomised controlled trial will aim to evaluate the combined effects of Muscle Energy Technique (MET) and biofeedback strengthening, with and without Kinesiotaping (KT), on pain, posture, deep neck flexor strength, and…
- Trial name
- NCT07079319
- Testing
- MET + Biofeedback Strengthening + Kinesiotaping, MET + Biofeedback Strengthening
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Psoriasis (PsO), Vitiligo Vulgaris
Evaluation of Stigma Toward Patients With Alopecia Areata, Atopic Dermatitis, Vitiligo, and Psoriasis
Primary objective: The primary objective is to evaluate in the general population the difference between emotional reactions associated with facial involvement by four major dermatologic diseases: psoriasis, atopic dermatitis…
- Conditions
- Psoriasis (PsO), Vitiligo Vulgaris, Atopic Dermatitis, Areata Alopecia
- Trial name
- STIGMADERM (NCT06801821)
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Upper Crossed Syndrome
Comparative Effect of Janda's Approach and Mckenzie Exercises in Patients With Upper Cross Syndrome
This study was conducted compare the effect Janda's Approach and Mckenzie Excercises in patients with Upper Crossed Syndrome
- Trial name
- JAM-USC (NCT07841639)
- Testing
- McKenzie Treatment, Janda's Approach, Baseline Treatment
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Upper Cross Syndrome
Comparative Effects of Egoscue and Feldenkrais Exercises on in Upper Cross Syndrome
Upper cross syndrome is a common postural dysfunction that is caused due to alternating tightness and weakness in the opposite muscle groups of the neck, shoulders and upper back which results in abnormal postural deviations.
- Trial name
- NCT07628413
- Testing
- Egoscue exercises, Feldenkrais exercises
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Vitiligo
Narrowband UVB Treatment in Patients With Vitiligo
The study offers narrowband UVB light therapy to patients who have 5% of their body involved with vitiligo. The hypothesis is that Narrowband UVB promotes melanocyte proliferation in vitiligo lesions.
- Trial name
- NCT00398723
- Testing
- Narrowband UVB
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mary Sullivan-Whalen
Vitiligo
Comparison of Efficacy and Safety of 0.1% Tacrolimus and 0.1% Mometasone Furoate for Adult Vitiligo
Vitiligo has remained a difficult disease to treat. Previous available therapies are often ineffective. It usually takes several months or years for complete repigmentation and some areas of the body get at best only partial…
- Trial name
- NCT01333410
- Testing
- tacrolimus ointment, Mometasone furoate
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Vitiligo, Hearing Loss
Audiological Disturbances in Vitiligo
The purpose of this study is to determine wether vitiligo patients have more audiological abmnormalities, than the healthy population.
- Trial name
- NCT00484224
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Oculocutaneous Albinism (OCA)
Safety and Efficacy of a Single Suprachoroidal Injection of JWK010 Gene Therapy in Subjects With Oculocutaneous Albinism Type 1 (OCA1)
Oculocutaneous albinism (OCA) is the most common type of albinism. People with OCA have little or no pigment (melanin) in their eyes, skin, and hair.
- Trial name
- NCT07313618
- Testing
- JWK010 gene therapy
- Where
- China
- Volunteers
- 18 people
- Sponsor
- West China Hospital
Vitiligo
Prostaglandin F2-alpha (PGF2α) in Vitiligo
study the cutaneous expression of PGF2α in vitiligo patients and compare it with normal control subjects.
- Trial name
- NCT03755830
- Testing
- Skin biopsy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitiligo
ERASE VITILIGO Early Repigmentation Approach for Stopping the Evolution of VITILIGO Prospective Multicentric Interventional Study With Blinded Evaluation
Vitiligo affects 1 to 2% of worldwide population and has a demonstrated impact on the quality of life. Optimal treatment of vitiligo requires to target the auto-immune inflammatory response (to halt the depigmentation process)…
- Trial name
- ERASE (NCT04843059)
- Testing
- The resident memory T-cell infiltrate in perilesional vitiligo skin
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gingival Hyperpigmentation
Gingival Depigmentation With Diode and Er,Cr:YSGG Laser: A Split-mouth Trial
Gingival hyperpigmentation is a common physiological condition caused by excessive melanin deposition in oral mucosa, negatively affecting smile esthetics.
- Trial name
- Laser (NCT07520266)
- Testing
- Er,Cr:YSGG laser, Diode laser
- Where
- 2 sites in Vietnam
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Albinism, Ocular
Genetic Determinant of Foveolar Hypoplasia in Parents of Albinos Children
Fovea plana could be the phenoyipic translation of a genetic anomaly in one of the genes identified in albinisme
- Trial name
- ALAFOR (NCT03959605)
- Testing
- blood sample for genetic test, Ophtalmological examination
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Vitiligo, PHOTOPROTECTION
Photoprotection Habits in Patients With Vitiligo
Intro: Patients with vitiligo have a reduced protection on depigmented areas. To date, however, little is known about photoprotection habits in patients with vitiligo even though these patients are thought to have a decreased…
- Conditions
- Vitiligo, PHOTOPROTECTION, SUN-EXPOSITION, FITZPATRICK SCALE
- Trial name
- VITISUN (NCT03323125)
- Testing
- Self-Assessment Questionnaire
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypopigmentation
Characterization of Bacterial and Mycosis Skin Flora in Seborrheic Macular Hypopigmentation - Microbiome
Hypopigmented skin changes are commonly encountered by dermatologists. A new dermatological entity was identified as scattered, hypopigmented oval-shaped macules and patches distributed mostly in seborrheic area of the face and…
- Trial name
- Microbiome_SHM (NCT06908889)
- Testing
- Skin's lesion patients, Skin's lesion vulunteers
- Where
- 3 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Vitiligo, Maintenance Therapy
Maintenance Therapy of 308-nm Excimer Laser Therapy in Patients With Vitiligo
Although vitiligo is difficult to cure, recurrences are frequent after treatment, and many patients suffer from concerns about recurrence as well as disease.
- Conditions
- Vitiligo, Maintenance Therapy, the 308-nm Excimer Laser, Recurrence
- Trial name
- NCT03384459
- Testing
- the 308-nm excimer laser
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- The Catholic University of Korea
Cross Syndrome
Comparison of Stretching and MET in Lower Cross Syndrome
The aim of the study is to compare the effects of stretching exercises \& muscle energy techniques in the management of lower cross syndrome and to find the effective treatment in the lower cross syndrome management.
- Trial name
- NCT04668040
- Testing
- Muscle energy technique, Stretching
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University