Clinical trials: Hyperventilation Syndrome
Hyperventilation Syndrome, Hypocapnia
Comparison of Transcutaneous Vs End-tidal CO2 Pressure Measurements in Hyperventilation Syndrome Diagnosis
Hyper Ventilation Syndrome is a frequent disease affecting adults whose diagnosis is often belated or even unrecognized due to the lack of "gold standard" criteria.
- Conditions
- Hyperventilation Syndrome, Hypocapnia, Alkalosis, Respiratory, Hyperventilation
- Trial name
- TCvsPETCO2 (NCT03614806)
- Testing
- Simultaneous Transcutaneous and End-tidal CO2 measurements
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Rouen
Interface, Mask, Continuous Positive Airway Pressure (CPAP)
CPAP and NIV Interfaces : Side-effects in Home Care Patients
Home ventilation techniques consist mainly of two techniques, Continuous Positive Airway Pressure or CPAP and Non Invasive Ventilation or NIV. Whether for CPAP or NIV, pressures are delivered to the patient via an interface.
- Conditions
- Interface, Mask, Continuous Positive Airway Pressure (CPAP), Non Invasive Ventilation (NIV), Hyperventilation Anxiety
- Trial name
- InterfaceVent (NCT03013283)
- Testing
- self questionnaire
- Where
- 2 sites in France
- Volunteers
- 6,000 people
- Sponsor
- University Hospital, Montpellier
COVID-19, Hyperventilation Syndrome
Relationship Between Hyperventilation Syndrome and SARS-CoV-2 Infection
Following an acute COVID-19 infection, many patients suffer from long lasting physical symptoms that may greatly impair quality of life.
- Trial name
- Hypercovid (NCT05224830)
- Testing
- Nijmegen questionnaire score
- Where
- France
- Volunteers
- 2,846 people
- Sponsor
- Central Hospital, Nancy, France
Cold Exposure, Hyperventilation
Effects of Cold Exposure and Breathing Techniques on Immune Response
Inflammatory cytokines play a pivotal role in rheumatoid arthritis (RA) and innovative non-pharmacological therapies aimed at limiting cytokine production are highly warranted.
- Conditions
- Cold Exposure, Hyperventilation, Inflammation, Endotoxemia
- Trial name
- EXPOCOL (NCT03240497)
- Testing
- Cold Exposure, Strength Ventilation
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Sepsis, Septic Shock
Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients
Alterations of acid-base equilibrium are very common in critically ill patients and understanding their pathophysiology can be important to improve clinical treatment.
- Conditions
- Sepsis, Septic Shock, Critical Illness, Respiratory Acidosis
- Trial name
- ENTERPRISE (NCT03966664)
- Testing
- In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in isolated plasma., In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in whole blood, Biomolecular analysis of plasma proteins.
- Where
- 2 sites in Czechia, Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Persistent Physical Symptoms (PPS)
CBT Plus SMC Compared to SMC for Persistent Physical Symptoms in Secondary Care (PRINCE)
Brief Summary: Persistent Physical Symptoms (PPS), also known as medically unexplained symptoms (MUS) is a term used to describe a range of persistent bodily symptoms for which the exact cause is unclear.
- Trial name
- PRINCE (NCT02426788)
- Testing
- Cognitive behavioural therapy (CBT)
- Where
- 7 sites in United Kingdom
- Volunteers
- 324 people
- Sponsor
- King's College London
Emergencies, Heart Failure
The Use of a Monitoring Device by General Practitioners During Out-of-hours Care
All calls that end up on the out-of-hours general practitioners' service (OHGPS), which contain a demand for an urgent home visit, are passed on to the on-call general practitioner (GP).
- Conditions
- Emergencies, Heart Failure, Pulmonary Embolism, Acute Exacerbation of Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05222711
- Testing
- Use of the PICO(TM) monitoring device
- Where
- Belgium
- Volunteers
- 866 people
- Sponsor
- KU Leuven
Low Back Pain, Recurrent, Hyperventilation Syndrome
Hyperventilation in Patients With Chronic Low Back Pain
Low back pain (LBP) is the leading cause of disability worldwide. Impaired postural control is a key factor in the development and maintenance of LBP.
- Trial name
- HELBP (NCT04074798)
- Testing
- assessment of hyperventilation, postural control and psychological behavior
- Where
- Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Postural Orthostatic Tachycardia Syndrome, Hypocapnia
Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hypocapnia
Postural tachycardia syndrome (POTS) is the most common chronic cause of postural lightheadedness, and upright confusion afflicting many Americans, mostly young women.
- Conditions
- Postural Orthostatic Tachycardia Syndrome, Hypocapnia, Hyperventilation
- Trial name
- NCT05923840
- Testing
- Chemoreflex Testing, Baroreflex testing, Orthostatic stress testing
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- New York Medical College
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Interstitial
Assessment of Continuous Measurement of Transcutaneous CO2 for Evaluation of Alveolar Dead Space During Exercise
The study aim is to monitor, during exercise tests carried out in various conditions, the alveolar dead space, by means of continuous transcutaneous measurement of Pt CO2, which would be used as a surrogate for arterial PaCO2.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Interstitial, Chronic Heart Failure, Pulmonary Arterial Hypertension
- Trial name
- TEASE (NCT03718780)
- Testing
- simultaneous determination of PaCO2 and PtCO2, Hyperventilation test, Exercise test
- Where
- 4 sites in France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Hyperventilation Syndrome
Impact of Respiratory Rehabilitation on Quality of Life in Patients With Hyperventilation Syndrome
The hyperventilation syndrome is a quite frequent pathology, affecting up to 10% of the general population and 40% of the asthmatic population.
- Trial name
- RESPIR-HVS (NCT04668638)
- Testing
- Respiratory rehabilitation
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Hyperventilation Syndrome
Work Productivity in Hyperventilation Syndrome
Hyperventilation syndrome is associated with impaired quality of life. The aim of the study is to assess the relationship between work productivity, including absenteeism and presenteeism, and the severity of hyperventilation…
- Trial name
- WHY (NCT03292523)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Epilepsy, Absence
Does Body Positioning Affect the Yield of Hyperventilation in Routine Pediatric Electroencephalography - EEG Studies?
Children referred for routine EEG studies for suspected absence seizures will be asked, upon caregiver's informed consent, to perform 3 minutes of hyperventilation both in the supine position and while sitting up.
- Trial name
- NCT02766595
- Testing
- hyperventilation while sitting up during routine EEG
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Pulmonary Arterial Hypertension
Prevalence of the Hyperventilation Syndrome in Pulmonary Arterial Hypertension
Dyspnea is a major symptom in pulmonary arterial hypertension and people with the same haemodynamic have generally different degree of dyspnea in pulmonary arterial hypertension.
- Trial name
- HYPER2 (NCT03810443)
- Testing
- Hyperventilation test
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiration Disorder, Hyperventilation Syndrome
Dysfunctional Breathing: Characterisation and Assessment
Dysfunctional breathing (DB) is a respiratory condition characterised by an abnormal breathing pattern, among other complaints, that can occur either in the absence of other pathophysiology (primary DB), e.g.
- Conditions
- Respiration Disorder, Hyperventilation Syndrome, Breathlessness, Breath Shortness
- Trial name
- NCT03043469
- Testing
- Short-form survey instrument, Demographic data, Hospital Anxiety and Depression Scale
- Where
- United Kingdom
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Brunel University
Stroke, Hyperventilation Syndrome
Symptomatic Hyperventilation in Individuals Living With Stroke
This study will investigate the effects of hyperventilation syndrome on respiratory muscle strength, respiratory muscle endurance, pulmonary functions, and functional capacity in individuals living with stroke, and in this…
- Trial name
- NCT07840703
- Testing
- Respiratory Function, Respiratory Muscle Strength, and Functional Capacity Assessments
- Volunteers
- 92 people
- Sponsor
- Istinye University
Hyperventilation Syndrome
Turkish Version of Nijmegen Questionnaire
The study aims to provide Turkish version of Nijmegen Questionnaire for the evaluation of respiratory dysfunction in asthmatic subjects.
- Trial name
- NCT04254952
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Hacettepe University
Post COVID-19 Condition (PCC), Dysfunctional Breathing
Dysfunctional Breathing in Post COVID-19 Condition.
The goal of this observational study with a cross-sectional design is to investigate what signs, symptoms and assessment which can describe and explain dysfunctional breathing in patients with post COVID-19 condition.
- Conditions
- Post COVID-19 Condition (PCC), Dysfunctional Breathing, Breathing Pattern Disorder, Post-Acute COVID-19 Syndrome
- Trial name
- DB-PCC (NCT06776263)
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Hyperventilation Syndrome
Nasal Ventilation Versus Voluntary Hypoventilation in the Rehabilitation of Hyperventilation Syndrome
The main objective of this study is to measure the effect (at 3 months) of dyspnea control rehabilitation with nasal ventilation versus standard rehabilitation, in dyspneic patients with hyperventilation syndrome.
- Trial name
- RehabSHV (NCT03159429)
- Testing
- Standard rehabilitation, Nasal breathing rehabilitation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Montpellier
Difficult Asthma, Severe Persistent Asthma
Prevalence of Hyperventilation Syndrome in Difficult Asthma
Most of asthmatics patients remain uncontrolled despite an inhaled steroids treatment. Chronic hyperventilation syndrome (also called Idiopathic Hyperventilation) occurs in 20 to 40% of asthmatic patients.
- Conditions
- Difficult Asthma, Severe Persistent Asthma, Hyperventilation Syndrome
- Trial name
- PRESH (NCT01862289)
- Testing
- Diagnostic of chronic hyperventilation syndrome
- Where
- France
- Volunteers
- 151 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris