Clinical trials: Hyperthermia
FIGO Stage IIC-IV Ovarian Carcinoma, Fallopian Tube Carcinoma
Heated Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Peritoneal Cancer
This phase I trial studies the side effects and best dose of heated carboplatin given into the abdomen at the time of surgery in treating patients with stage II-IV ovarian, fallopian tube, or peritoneal cancer.
- Conditions
- FIGO Stage IIC-IV Ovarian Carcinoma, Fallopian Tube Carcinoma, Peritoneal Carcinoma
- Trial name
- NCT02199171
- Testing
- carboplatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Irvine
Rheumatic Heart Disease, Rheumatic Heart Disease in Children
Clinical Trial Phase I/IIa to Evaluate the Safety and Immunogenicity of StreptInCor
This is a Phase I/IIa, randomized, double-blind, placebo-controlled, dose-escalation clinical trial to test the candidate vaccine StreptInCor.
- Conditions
- Rheumatic Heart Disease, Rheumatic Heart Disease in Children, Vaccine Adverse Reaction, Rheumatic Diseases
- Trial name
- StreptInCorVac (NCT07078357)
- Testing
- StrepIncor
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Yellow Fever (Healthy Volunteers), Biopsy/Methods
Baseline Assessment of Skin Resident Memory T Cells in Healthy Unvaccinated Participants
In The main GeKoSkimm trial (= A randomized controlled trial to compare the immunogenicity and skin imprinting of intradermal, subcutaneous and intramuscular yellow fever vaccination) the investigators try to understand whether…
- Trial name
- NCT07636551
- Testing
- Skin punch biopsy, Blood samples
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Acute Febrile Illness, Bacterial Infections
AI-Guided Proteomic Biomarker Panel for Differentiating Bacterial and Viral Infections in Acute Febrile Illness
This study is a proteomics-based diagnostic biomarker study conducted on the same patient cohort as the transcriptomic biomarker study (NCT065529754).
- Conditions
- Acute Febrile Illness, Bacterial Infections, Viral Infections, Sepsis
- Trial name
- NCT07205575
- Testing
- Proteomic Biomarker Panel
- Where
- China
- Volunteers
- 394 people
- Sponsor
- Qilu Hospital of Shandong University
Stroke, Acute Stroke
Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC)
The goal of this clinical trial is to evaluate whether a multicomponent nurse-led intervention (BEST CARE ICTUS_HC) can reduce stroke-related complications and improve recovery in adults (18 years and older) hospitalized with an…
- Conditions
- Stroke, Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- BESTCAREICTUS (NCT07627399)
- Testing
- BEST CARE ICTUS_HC BUNDLE
- Where
- 4 sites in Spain
- Volunteers
- 700 people
- Sponsor
- University of Malaga
Typhoid
Safety and Immunogenicity of a Vi-DT Typhoid Conjugate Vaccine
This is a Phase I, Randomized, observer-blinded, age de-escalating study. The study objectives are: 1. To evaluate the safety of 25 μg of Vi-DT typhoid conjugate vaccine administered at 0 and 4 weeks. 2.
- Trial name
- NCT02645032
- Testing
- Vi-DT, Typhim Vi®, VAXIGRIP®
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Heat Stress, Physiological Stress
Suitability of a 26 °C Indoor Environment for Mitigating Heat Strain in Young Adults
While an indoor upper temperature limit of 26 °C has been shown to protect heat-vulnerable older adults (DOI: 10.1289/EHP11651), this guideline has not been verified in young, habitually active adults.
- Conditions
- Heat Stress, Physiological Stress, Cognitive Change
- Trial name
- NCT07267598
- Testing
- Simulated indoor temperature upper limit
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Ottawa
Cardiovascular Risk Factor
Comparison of Electronic Cigarettes and Tobacco Cigarettes on Cardiovascular Function and Oxidative Stress
Background: Electronic cigarettes (e-cigarettes) are battery-powered devices heating a liquid (e-liquid) composed of propylene glycol and/or vegetable glycerin, and most commonly, nicotine to form an aerosol (vapor) that is…
- Trial name
- NCT03036644
- Testing
- e-cigarette (PG+VG without nicotine; low temperature), e-cigarette (PG+VG with nicotine; low temperature), e-cigarette (PG+VG without nicotine; high temperature)
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Gastric Cancer
Laparoscopic Gastrectomy With D2 Lymphadenectomy Combined With Hyperthermic Intraperitoneal Chemotherapy (HIPEC) or Not
The goal of this clinical trial is to learn about Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Locally Advanced Gastric Cancer after Laparoscopic Gastrectomy with D2 Lymphadenectomy.
- Trial name
- NCT05871099
- Testing
- Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Where
- China
- Volunteers
- 616 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Adenoid Hypertrophy, Adenoidectomy
Coblation Versus Suction Diathermy in Pediatric Adenoidectomy
The goal of this clinical trial is to compare two surgical procedures in endoscopic adenoidectomy including Coblation and Suction diathermy .
- Conditions
- Adenoid Hypertrophy, Adenoidectomy, Coblation Adenoidectomy, Suction Daithermy
- Trial name
- NCT06841432
- Testing
- adenoidectomy using coblatioion, adenoidectomy by Suction diathermy
- Where
- Egypt
- Volunteers
- 245 people
- Sponsor
- Al-Azhar University
Ovarian Cancer, Ovary Neoplasm
Cytoreductive Surgery(CRS) Plus Hyperthermic Intraperitoneal Chemotherapy(HIPEC) With Lobaplatin in Advanced and Recurrent Epithelial Ovarian Cancer
A phase III prospective study with the primary objective to compare the efficacy and safety of HIPEC( Hyperthermic Intraperitoneal Chemotherapy).
- Conditions
- Ovarian Cancer, Ovary Neoplasm, Ovarian Neoplasms, Epithelial Ovarian Cancer
- Trial name
- HIPECOV (NCT03371693)
- Testing
- HIPEC, CRS, IVCT
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Zhongnan Hospital
Yellow Fever, Yellow Fever Immunisation
A Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of MVA-BN Yellow Fever Vaccine With and Without Montanide ISA-720 Adjuvant in 18-45 Year Old Healthy Volunteers
This study is a multi-center, double-blind, placebo-controlled, Phase I study to evaluate the safety, reactogenicity, tolerability, and immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic-Yellow Fever (MVA-BN-YF) in…
- Trial name
- NCT02743455
- Testing
- ISA-720, MVA Smallpox Vaccine, MVA-BN Yellow Fever Vaccine
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gastric Adenocarcinoma
PHASE II EVALUATION OF CYTOREDUCTION SURGERY AND HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY (CRS/HIPEC) IN GASTRIC CANCER
This is a Phase II treatment study analyzing the role of preoperative chemotherapy, preoperative laparoscopic HIPEC, and gastrectomy with CRS/HIPEC in gastric adenocarcinoma patients with cytology-positive only carcinomatosis…
- Trial name
- NCT07178808
- Testing
- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Banner Health
Breast Cancer, Fever
Same Day Dosing of Pegfilgrastim in Breast Cancer Patients Undergoing Chemotherapy (TAC)
The purpose of this study is to provide data on the safety and efficacy of pegfilgrastim when administered on the same day versus the next day of chemotherapy, as measured by the duration of grade 4 neutropenia.
- Conditions
- Breast Cancer, Fever, Neutropenia
- Trial name
- NCT00115414
- Testing
- pegfilgrastim, docetaxel, doxorubicin
- Sponsor
- Amgen
Fever, Heart Rate
The Effect of Methods Used in Oral Antipyretic Administration on the Vital Findings of the Child With Fever
Fever, one of the most common clinical journeys of childhood, makes up a fraction of emergency room admissions. About us-30. High fever, which is one of the first schools in infancy and childhood, can cause health problems such…
- Conditions
- Fever, Heart Rate, Respiratory Rate, Pain
- Trial name
- NCT05366049
- Testing
- using a medicine pacifier to give acetaminophen
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pre-hypertension
Heat & Aerobic Training (HEAT) Study
This study is intended for inactive, middle-aged adults with untreated pre-hypertension who live in the Urbana-Champaign area, who are interested in a comprehensive program designed to enhance physical activity \& reduce blood…
- Trial name
- HEAT (NCT02546726)
- Testing
- Heat & Aerobic Training (HEAT), Exercise Only
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Illinois at Urbana-Champaign
Chikungunya Fever
Effects of Auriculotherapy on Pain and Functional Capacity of Individuals With Chikungunya Fever
Chikungunya fever is an acute viral disease, transmitted by the mosquito (Aedes aegypti), that triggers pain and disabling rheumatic manifestations.
- Trial name
- NCT03090685
- Testing
- True auriculotherapy with seeds
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Ceara
Bloodstream Infection, Acute Myeloid Leukemia
Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile Neutropenia
There is no specific recommendation about antimicrobial treatment length for documented infections in chemotherapy induced febrile neutropenia.
- Conditions
- Bloodstream Infection, Acute Myeloid Leukemia, Febrile Neutropenia
- Trial name
- NCT04910698
- Testing
- Antibiotic
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Poitiers University Hospital
Healthy Adult, Healthy Adolescents
Evaluation of IXCHIQ® Vaccine Immunogenicity
The goal of this clinical trial is to evaluate the quality and duration of the immune response against chikungunya virus elicited by the IXCHIQ® vaccine in healthy adults and adolescents.
- Trial name
- IMUNO-CHIQ (NCT07846293)
- Testing
- IXCHIQ vaccine
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mauro Martins Teixeira
Peritoneal Carcinoma, Ovarian Cancer
Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in Peritoneal Carcinomatosis From Ovarian Cancer (Cyto-chip 2)
Epithelial ovarian carcinoma (EOC) is one of the main cause of death from cancer in women in the Western world. It is often diagnosed at an advanced stage and the disease remains confined to the peritoneal cavity for much of its…
- Trial name
- Cyto-chip 2 (NCT03931304)
- Testing
- Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy procedure
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Hospices Civils de Lyon
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