Clinical trials: Hypertension (HTN), active
Hypertension (HTN), Diabetes (DM)
Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM)
The investigators are proposing a new team-based shared decision-making (SDM) program. The goal of this study is to see whether this program is practical and whether it may help adults with cardiometabolic risk factors and…
- Conditions
- Hypertension (HTN), Diabetes (DM), Hyperlipidaemia, Kidney Disease
- Trial name
- SDM in CKM (NCT07662616)
- Testing
- Team-based shared decision-making
- Volunteers
- 94 people
- Sponsor
- Johns Hopkins University
Hypertension (HTN), Diabetes
Evaluation of a New Virtual Care Pathway for Older Adults With Noncommunicable Diseases
The purpose of this study is to evaluate a newly developed virtual care program for older adults with chronic diseases (hypertension, diabetes and lipid disorders) whether it is feasible and economical to implement in the…
- Conditions
- Hypertension (HTN), Diabetes, Dyslipidaemia
- Trial name
- TeleCOOP-NCD (NCT07843238)
- Testing
- Teleconsultation care pathway for older adults with NCDs (TeleCOOP-NCD©)
- Where
- Malaysia
- Volunteers
- 160 people
- Sponsor
- National University of Malaysia
Hypertension (HTN)
Hypertension Treatment in Nigeria 2.0
The purpose of the second phase of the Hypertension Treatment in Nigeria (HTN 2.0) Program is to build upon the success of the first phase of the HTN Program (2020-2023), which implemented the WHO HEARTS package across 60 primary…
- Trial name
- HTN 2 (NCT07351162)
- Testing
- Implementation of a modified WHO HEARTS Hypertension Treatment Bundle
- Where
- 49 sites in Nigeria
- Volunteers
- 10,000 people
- Sponsor
- Washington University School of Medicine
Hypertension, Hypertension (HTN)
Clinical Decision Support Tool for the Treatment of Uncontrolled Hypertension
The goal of this clinical trial is to study whether having a clinical decision support (CDS) tool available to clinician use will more effectively lower BP 4 weeks after an outpatient visit compared with usual care.
- Conditions
- Hypertension, Hypertension (HTN), Blood Pressure, High, Blood Pressure Control
- Trial name
- AI-HTN (NCT07218198)
- Testing
- Standard medical treatment, Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- The Cleveland Clinic
Hypertension, Hypertension (HTN)
Common Carotid Artery-Renal Artery-Femoral Artery Survey for Hypertension
To evaluate both sides of the common carotid artery, renal artery, and femoral artery in Hypertension patient that cause of systemic arterial hypertension and/or the effects of target organ damage, both structural and functional…
- Conditions
- Hypertension, Hypertension (HTN), Artery Disease, Target Organ Damage
- Trial name
- CRF Survey (NCT07760623)
- Testing
- Diameter measurement, Velocity
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- DejthidaNathaphong
Hypertension (HTN)
Spinal Cord Stimulation for Blood Pressure Control in Hypertension
High blood pressure, also called hypertension, raises the risk of heart disease, stroke, and kidney disease. Medications work well for many people, but some people still have blood pressure that stays too high, or they have side…
- Trial name
- HTN-SCS (NCT07842315)
- Testing
- Lower Thoracic Spinal Cord Stimulation
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Calgary
Cardiovascular Diseases, Chronic Kidney Diseases
Improving the Collaborative Health of Adult Dyads
This study tests the efficacy of a dyadic intervention to mitigate the adverse health consequences of adults with pre-existing chronic health conditions and their informal carepartners (IC).
- Conditions
- Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus, Type 2, Chronic Disease
- Trial name
- NCT05370014
- Testing
- Integrating Community-based Intervention Under Nurse Guidance with Families (iCINGS FAM)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Hypertension (HTN), Hypertension ,Pregnancy
REmote Physical ACtivity Intervention for High Blood Pressure Postpartum
The purpose of this intervention is to help new mothers who had elevated blood pressure during pregnancy become more physically active after birth. The investigators will connect data from FitBits to the electronic health record.
- Conditions
- Hypertension (HTN), Hypertension ,Pregnancy, Physical Activity
- Trial name
- REACH BP (NCT07127731)
- Testing
- Patient Portal Messaging, FitBit EHR Linkage
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Hypertension (HTN)
Project HOPE (Hypertension Outreach Through Partnership and Engagement)
The goal of this study is to learn if a nurse-led, task-shifting, community-based program can help lower blood pressure in adults aged 25 and older with uncontrolled high blood pressure (hypertension) in Monrovia, Liberia.
- Trial name
- HOPE (NCT07681726)
- Testing
- Project HOPE Intervention
- Where
- Liberia
- Volunteers
- 150 people
- Sponsor
- Johns Hopkins University
Hypertension (HTN), Chronic Stress
Dual-Language B-MORE for Hypertension
This pilot study is a single-arm clinical feasibility trial evaluating the feasibility, acceptability, and preliminary efficacy of a brief adaptation of Mindfulness-Oriented Recovery Enhancement (B-MORE) for reducing stress and…
- Trial name
- NCT07623031
- Testing
- Behavioral: B-MORE (Brief Mindfulness-Oriented Recovery Enhancement)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida State University
Hypertension (HTN), Vascular Diseases
The BASIC-S Feasibility Study for Vascular Risk Reduction
Vascular risk factors drive stroke, heart disease, and dementia, but translating lifestyle guidelines into routine clinical care remains challenging.
- Conditions
- Hypertension (HTN), Vascular Diseases, Stroke, Dementia
- Trial name
- BASIC-S (NCT07755631)
- Testing
- BASIC-S Intervention, Standard / Usual Care
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Andrew Appleton
Cardiovascular Disease (CVD), Heart Failure
Study of the Progression of Chronic Cardiovascular Conditions
This study will collect physiologic data in patients with cardiovascular conditions and observe the natural history of those conditions for research purposes.
- Conditions
- Cardiovascular Disease (CVD), Heart Failure, Aortic Stenosis, Aortic Stenosis Disease
- Trial name
- OCORO (NCT07420907)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Prolaio
Hypertension (HTN)
Assessing the Feasibility of the "Heart Care Pairs" Intervention
The researchers will invite 30 patients in primary care who have high blood pressure to participate in this health program with a supportive partner of their choosing (these will be the "participant pairs").
- Trial name
- NCT07760350
- Testing
- Dyadic lifestyle intervention for CVD risk reduction
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Alabama at Birmingham
Hypertension (HTN), Food Insecurity
Navigating Hypertension and Food Insecurity
This multi-site randomized controlled trial uses a community-based approach to evaluate a Food as Medicine program for Native Hawaiian and Pacific Islander (NHPI) adults in Hawaii who have high blood pressure and difficulty…
- Trial name
- NCT07544836
- Testing
- Produce Prescription Only, Community Health Worker navigated Produce Prescription
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Hawaii
Hypertension (HTN)
Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension
High blood pressure (hypertension) is a leading risk factor for cardiovascular diseases and may contribute to poor health and premature death.
- Trial name
- NCT07213479
- Testing
- Isometric Exercise and Lifestyle Change Advice, Lifestyle Change Advice
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Northumbria University
Chronic Kidney Disease, Hypertension (HTN)
Investigating Vascular Properties of HEMI and SPG Signals in Individuals With or at Risk for Chronic Kidney Disease
This prospective, single-center clinical investigation conducted in France will evaluate two non-invasive investigational devices (HEMI and SPG-NINOX) designed to assess microcirculation in adults.
- Conditions
- Chronic Kidney Disease, Hypertension (HTN), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- STIMULUS-CKD (NCT07604922)
- Testing
- HEMI device, SPG-NINOX device
- Where
- France
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Hypertension (HTN)
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
The purpose of this extension study is to collect additional safety and efficacy on QCZ484 for hypertensive patients who successfully completed the parent study, CQCZ484A12201 or additional QCZ484 studies as specified in the…
- Trial name
- NCT07543120
- Testing
- QCZ484
- Where
- 25 sites in United States, Japan and 1 more
- Volunteers
- 323 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension (HTN), Preeclampsia
Mobile Health Program for Post-Preeclampsia Hypertension
Strategies targeted to optimize hypertension (HTN) control for midlife women after hypertensive disorders of pregnancy (HDP) have not been studied, despite evidence of a critical need.
- Conditions
- Hypertension (HTN), Preeclampsia, Hypertensive Disorders of Pregnancy (HDP)
- Trial name
- NCT07599579
- Testing
- Coaching application, Home-based blood pressure monitoring, WebMD
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Hypertension, Hypertension (HTN)
FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control
The goal of this clinical trial is to treat both hypertension and obesity in adults using a food is medicine framework. Participants will be randomized 1:1 to FIM+DASH or usual-care control.
- Conditions
- Hypertension, Hypertension (HTN), Obesity & Overweight
- Trial name
- FIM+DASH (NCT07332741)
- Testing
- FIM intervention arm, FIM Usual Care Arm
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois at Chicago
Hypertension (HTN)
Finerenone and Empagliflozin Combination in Obesity With Hypertension: A 12-Week Prospective, Parallel-design, Double-blind, Randomized, Placebo-controlled Trial
The EFFORT Study (Empagliflozin and Finerenone Combination in Obesity with Hypertension) is a 12-week, randomized, double-blind, placebo-controlled trial that aims to test whether combining empagliflozin (10 mg/day) with…
- Trial name
- NCT07678151
- Testing
- Empagliflozin and Finerenone
- Where
- 2 sites in China
- Volunteers
- 260 people
- Sponsor
- Heart Health Research Center