Clinical trials: Hyperphagia
Obesity
Exercise as a Buffer Against Stress-induced Overeating
The purpose of this study is to examine the psychological benefits of chronic exercise as well as the effects of exercise training on eating behaviors and stress-induced overeating in overweight and obese women.
- Trial name
- NCT02936076
- Testing
- Exercise intervention, Delayed exercise intervention
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Prader-Willi Syndrome
PWS European Blood Bank for Infants and Controls From 0 to 48 Months
The present project aims to determine the underlying mechanisms for the switch from failure to thrive to excessive weight gain and hyperphagia with impaired satiety in PWS.
- Trial name
- NCT02529085
- Testing
- blood samples
- Where
- 6 sites in Belgium, France and 4 more
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Obesity
Learning Theory to Improve Obesity Treatment
The purpose of this study is to optimize an obesity treatment program targeting overweight 8-12 year old children using "Cue Exposure Training".
- Trial name
- iROC (NCT01708785)
- Testing
- Single food Cue Exposure Treatment, Multiple food Cue Exposure Treatment, Partial Reinforcement - Enhanced Cue Exposure Treatment
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Bulimia Nervosa
Neural Bases of Multiple Forms of Self-regulatory Control in Bulimia Nervosa
The purpose of this study is to investigate areas of the brain responsible for self-regulation in adult women who have never had an eating disorder with women who have bulimia nervosa.
- Trial name
- SRBN (NCT02997475)
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Prader-Willi Syndrome, Hyperphagia
Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome
This Phase 2b/3 double-blind, placebo-controlled study will evaluate the safety, tolerability, and effects of livoletide on food-related behaviors in patients with Prader-Willi Syndrome (PWS).
- Trial name
- ZEPHYR (NCT03790865)
- Testing
- Livoletide
- Where
- 37 sites in United States, Australia and 6 more
- Volunteers
- 158 people
- Sponsor
- Millendo Therapeutics SAS
Malnutrition
Dose Comparison of Amino Acids on Growth in Premature Neonates
Malnutrition is a common problem in the neonatal intensive care unit. Recent studies indicate that prematurely born neonates commonly develop a severe nutritional deficit during the first weeks after birth, referred to as…
- Trial name
- NCT00120926
- Testing
- Parenteral Nutrition
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Pediatrix
Bulimia
Effect of a CCK-1R Agonist on Food Intake in Humans
The ultimate aim of this study is to test the hypothesis that the oral cholecystokinin (CCK) agonist GSKI181771X will reduce the size of a binge meal among individuals with Bulimia Nervosa. The study will be conducted in phases.
- Trial name
- GSK (NCT00600743)
- Testing
- GSKI181771X (CCK-1R agonist), Instructions to binge eat, Instructions to eat normally
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Bulimia Nervosa, Anorexia Nervosa
Repetitive Transcranial Magnetic Stimulation of the DMPFC for Anorexia and Bulimia: an Open-Label Case Series
This project proposes to perform a pilot study of fMRI targeted Dorsomedial Prefrontal Cortex repetitive transcranial magnetic stimulation (DMPFC-rTMS) on individuals diagnosed with Bulimia Nervosa (BN) and Anorexia Nervosa (AN).
- Trial name
- NCT04409704
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Binge Eating, Binge-Eating Disorder
Development and Initial Tests of Reward Re-Training: A Novel Treatment For Reward Dysfunction
The purpose of this study is to test a novel treatment for binge eating that will be compared to a waitlist control group. The investigators are seeking to target factors that might influence binge eating by increasing reward in…
- Conditions
- Binge Eating, Binge-Eating Disorder, Bulimia Nervosa
- Trial name
- Recharge (NCT03942874)
- Testing
- Group Reward Retraining
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Drexel University
Binge Eating Disorder
Integrative Cognitive-Affective Therapy for Binge Eating Disorder
The purpose of the study is to test a newly developed individual psychotherapy treatment for binge eating disorder in adults. This treatment is a type of individual psychotherapy called Integrative Cognitive-Affective Therapy…
- Trial name
- NCT02043496
- Testing
- Integrative Cognitive-Affective Therapy, CBT-Guided Self Help
- Where
- 2 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Carcinoma Surgery, Parenteral Nutrition
The Impact of Omega-3 Fat Emulsion on Clinical Outcome of Post-Operative Cancer Patients
The purpose of this study is to evaluate clinical safety and effect of Omega-3 fat oil emulsion on outcome in post-operative cancer patients.
- Conditions
- Carcinoma Surgery, Parenteral Nutrition, Post-Operative Hospital Stay
- Trial name
- NCT00292279
- Testing
- Omega-3 fish oil emulsion (Omegaven ), long-chain triglyceride
- Where
- 5 sites in China
- Volunteers
- 206 people
- Sponsor
- Sino-Swed Pharmaceutical Corporation
Parenteral Nutrition Associated Liver Disease PNALD, Cholestasis
Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis
The purpose of this study is to determine if established parenteral nutrition (PN) associated liver disease can be reversed or its progression halted by using a parenteral fat emulsion prepared from fish oil as measured by…
- Trial name
- NCT00826020
- Testing
- Omegaven™
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Nebraska
Eating Disorders
Randomized Study Assessing a Program of Body Dissatisfaction Psychological Care in Eating Disorders
Eating disorders (ED) are a major public health problem for which current treatments are insufficiently effective. The transdiagnostic approach of eating disorders highlights body dissatisfaction (BD) as a major factor in the…
- Trial name
- INCCA (NCT05227625)
- Testing
- body dissatisfaction management group, Relaxation Group
- Volunteers
- 128 people
- Sponsor
- University Hospital, Montpellier
Overweight, Obesity and Other Hyperalimentation
Taking Action to Thrive - A Healthy Lifestyle Intervention Pilot Study
There have been some preliminary studies, primarily in animals, that suggest that exposure to some of the chemicals in our everyday environment, such as the chemicals found in plastics, may cause weight gain.
- Trial name
- THRIVE (NCT03478345)
- Testing
- endocrine disruptor chemical reduction intervention
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- George Washington University
Obesity, Overweight
Family Based Treatment for Weight Loss With Breakfast Prescription
The purpose of this study is to evaluate whether a behavioral weight loss group in conjunction with a prescribed breakfast can help children between 8 and 12 years of age change their behaviors to help them lose weight and become…
- Conditions
- Obesity, Overweight, Overeating, Weight
- Trial name
- FAB (NCT02467036)
- Testing
- Family Based Behavioral Treatment
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Parenteral Nutrition
Clinical Trial to Evaluate the Safety and Efficacy of IN-C006 Peri Inj. Compared With RPN301
This study is designed to evaluate the safety and efficacy of IN-C006 Peri inj. and RPN301 in postoperative patients requiring central parenteral nutrition.
- Trial name
- NCT05337228
- Testing
- IN-C006 Peri inj., RPN301
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- HK inno.N Corporation
Over Eating
Fat Cell Size and Overfeeding and Etopic Study
It has been shown that large fat cells are associated with more risks for insulin resistance and more cardiovascular risk factors such as high cholesterol or triglycerides.
- Trial name
- EAT (NCT01672632)
- Testing
- Overfeeding
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Binge-Eating Disorder
eBEfree - an ICT Adaptation of BEfree
The eBEfree project aims at testing the effectiveness of an information and communication technology-based delivery version of BEfree in individuals with obesity and Binge Eating Disorder (BED).
- Trial name
- eBEfree (NCT04101032)
- Testing
- eBEfree
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Obesity, Overfeeding
Overeating Different Fats and Influence on Muscle Mass and Body Fat Accumulation
To investigate metabolic and molecular response to fatty acid-specific overfeeding in overweight subjects, in relation to changes in ectopic fat, lean tissue mass and insulin sensitivity
- Conditions
- Obesity, Overfeeding, Muscle Mass, Body Composition
- Trial name
- LIPOGAIN-2 (NCT02211612)
- Testing
- PUFA-group, SFA-group
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Abdominal Trauma
Personalized Nutrition to Improve Recovery in Trauma
The purpose of this study is to determine if a particular method of providing nutrition improves the outcomes of patients in the intensive care unit (ICU) who have undergone abdominal surgery following trauma and would require…
- Trial name
- SeND Home (NCT06065202)
- Testing
- Nutrition Supplement
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Duke University