Clinical trials: Hyperinflation Lung
Chronic Obstructive Pulmonary Disease, Hyperinflation
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation
The purpose of the study is to evaluate the effect of BGF MDI compared with placebo MDI on cardiac and lung function when administered in participants diagnosed with COPD and hyperinflation.
- Trial name
- ORATOS (NCT07073950)
- Testing
- Budesonide/Glycopyrronium/Formoterol Fumarate, Metered dose inhaler
- Where
- 7 sites in Germany, United Kingdom
- Volunteers
- 56 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Hyperinflation
Effect of Simeox® on Residual Volume in COPD Patients With Pulmonary Hyperinflation
Brief Summary People with severe chronic obstructive pulmonary disease (COPD) often have too much air trapped in their lungs (pulmonary hyperinflation). This makes it hard to breathe and reduces quality of life.
- Trial name
- SIMEO-RV COPD (NCT07665931)
- Testing
- Simeox
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
Secondhand Smoke, Air Trapping
Secondhand Smoke Respiratory Health Study
Exposure to secondhand tobacco smoke (SHS) is associated with diverse health effects in nonsmokers. Flight attendants (FA) who worked on commercial aircraft before the ban on tobacco smoking (exposed FAs) had high, long-term…
- Conditions
- Secondhand Smoke, Air Trapping, Tobacco, Airflow Limitation
- Trial name
- NCT02797275
- Testing
- Albuterol
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- University of California, San Francisco
COPD, Hyperinflation
Effect of Elastic Chest Compression on Functional Exercise Capacity and Respiratory Performance in Patients With COPD
The goal of this clinical trial is to investigate the effects of elastic chest compression on functional exercise capacity and respiratory performance of patients with COPD.
- Trial name
- NCT06519474
- Testing
- Theraband chest compression
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- National Taiwan University Hospital
Emphysema, COPD
Mind The Gap - Crossing Borders Study
Rationale: A big step forward and great opportunity to improve overall efficacy of bronchoscopic lung volume reductioen is to combine treatment modalities aiming to close the dependent collateral channels and then proceed with…
- Conditions
- Emphysema, COPD, Hyperinflation Lung
- Trial name
- NCT04256408
- Testing
- Bronchoscopic transparenchymal interlobar fissure closure using Aeriseal
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- University Medical Center Groningen
Copd, Emphysema
4D Medical X-ray Velocimetry for Bronchoscopic Lung Volume Reduction Targeting
This study will investigate the utility of 4D Medical's X-ray Velocimetry (XV) imaging analysis software for the detection of hyperinflation, and compare endobronchial valve placement outcomes with predictive indices obtained…
- Conditions
- Copd, Emphysema, Hyperinflation
- Trial name
- NCT04786171
- Testing
- 4D X-ray Velocimetry
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Vanderbilt University Medical Center
Hypoxaemia During Surgery, Lung Hyperinflation
HFHO vs CPAP During Thoracic Surgery
A single institutional cross-over study design to compare between high flow humidified oxygen (HFHO) device versus conventional CPAP for non-ventilated lung during thoracic surgery.
- Trial name
- NCT03894072
- Testing
- CPAP, HFHO
- Where
- Thailand
- Volunteers
- 28 people
- Sponsor
- Mahidol University
Pneumothorax, Pulmonary Contusion
Electrical Impedance Imaging of Patients on Mechanical Ventilation
The goal of this study is to evaluate the sensitivity and specificity of Electrical Impedance Tomography (EIT) as a bedside diagnostic tool for lung pathologies in patients who are mechanically ventilated.
- Conditions
- Pneumothorax, Pulmonary Contusion, Pleural Effusion, Pulmonary Edema
- Trial name
- NCT02232841
- Testing
- Mechanical Ventilation, CT Scan
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Colorado State University
COPD, Hyperinflation
Acute Effect of Pulmonary Desufflation on Cardiac Performance in COPD Patients
Chronic Obstructive Pulmonary disease (COPD) is one of the major clinical entities that causes thousands of deaths every year all over the world and weights a lot on the health care system of every country in terms of direct and…
- Conditions
- COPD, Hyperinflation, Right Cardiac Failure
- Trial name
- NCT01996124
- Testing
- Indacaterol Fumarate
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Milan
COPD, Dyspnea
Device-guided Breathing for Shortness of Breath in COPD
Although drug therapies and pulmonary rehabilitation have greatly improved COPD symptoms, as many as 50% of patients with severe COPD have inadequately controlled dyspnea.
- Conditions
- COPD, Dyspnea, Hyperinflation
- Trial name
- NCT01286181
- Testing
- Twice daily practice of device-guided slow breathing.
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Mayo Clinic
Dynamic Lung Hyperinflation, COPD Patients
Daily Activities Are Sufficient to Induce Dynamic Pulmonary Hyperinflation and Dyspnea in Chronic Obstructive Pulmonary Disease Patients
Introduction: Chronic obstructive pulmonary disease is a condition characterized by airflow limitation usually progressive and associated with inflammatory response of lung noxious particles.
- Conditions
- Dynamic Lung Hyperinflation, COPD Patients, Activities of Daily Livin.
- Trial name
- Hyperinflation (NCT01475812)
- Testing
- Hyperinflation and ADL
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Federal University of São Paulo