Clinical trials: Hydroxyapatite
Tooth Hypersensitivity
Hypersensitivity and Color Changes of Bleached Teeth Using Different Remineralizing Agents
The aim of this in vivo study is to evaluate the post-bleaching enamel hypersensitivity and the possible color changes following the application of arginine and nano-hydroxyapatite remineralizing solutions after enamel bleaching…
- Trial name
- NCT04875000
- Testing
- Remineralizing agent I application, Remineralizing agent II application, Remineralizing agent III application
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Bone Substitutes, Calcium Phosphates
Biphasic Calcium Phosphate vs. Hydroxyapatite in Sinus Floor Elevation
Twenty patients scheduled for lateral-window sinus floor Elevation (SFE) are randomized into two groups: use of SYMBIOS® Biphasic Bone Graft Material (Group 1) or of Algipore® Bone Substitution Material (Group 2).
- Conditions
- Bone Substitutes, Calcium Phosphates, Hydroxyapatite, Rhodophyta
- Trial name
- NCT04331314
- Testing
- Use of Symbios Bone Graft Material, Algipore Bone Substitution Material
- Volunteers
- 20 people
- Sponsor
- Medical University of Graz
White Spot Lesion
Effect of Poly Amido Amine Dendrimer, Nano-hydroxyapatite
Dental caries is a common oral disease. The process of caries formation is a cycle of remineralization and demineralization with various stages being either reversible or irreversible.
- Trial name
- NCT05771077
- Testing
- Poly(Amidoamine) dendrimer
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Egymedicalpedia
Periodontitis
Evaluation of Advanced PRF Combined With Nano-crystalline Hydroxyapatite for Management of Grade II Furcation Defects
this study is to evaluate the use of advanced platelet rich fibrin (A-PRF) + nano-crystalline hydroxyapatite bone substitute combined with open flap debridement (OPD) versus open flap debridement alone in the management of…
- Trial name
- NCT03804086
- Testing
- Advanced PRF (A-PRF) + nano-crystalline hydroxyapatite bone substitute combined with open flap debridement, Open flap debridement
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hadeer Ashraf Hassan Roushdy
Gingival Inflammation and Loss the Orthodontic Mini-screws
Strontium-Hydroxyapatite Coated Mini-Screws: Antibacterial Effect and Stability
This randomized controlled clinical trial aims to evaluate the antibacterial efficacy and stability of strontium-incorporated hydroxyapatite (Sr-HA) coated orthodontic mini-screws (OMSs) used for maxillary canine retraction.
- Trial name
- NCT07105969
- Testing
- Strontium Incorporated Hydroxyapatite [Sr-HA] coated mini-screws purchased from Dentarum company
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Caries
The Preventive Effect of 2-years Use of Hydroxyapatite Containing Toothpastes in Children.
The aim of this RCT was to verify the caries preventive efficacy of toothpastes containing biomimetic hydroxyapatite (H.A.) complex in children compared to traditional fluoridated toothpastes.
- Trial name
- NCT04906291
- Testing
- Toothpaste use
- Where
- Italy
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Caries,Dental
Nano-hydroxyapatite and Ozone - Effect on Approximal Initial Caries
Objectives: to assess the efficiency of three methods of enamel remineralization on initial approximal caries: 1. a nano-hydroxyapatite gel, 2. gaseous ozone therapy 3. combination of a nano-hydroxyapatite gel and ozone.
- Trial name
- NCT04147091
- Testing
- ApaCare & Repair
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Tooth Decay, Hydroxyapatite
Hydroxyapatite-toothpaste and Enamel Caries in the Primary Dentition
This multicenter, non-inferiority trial randomized, double-blind, active controlled parallel group study evaluates the hypothesis that the home regular use of a toothpaste containing microcrystalline hydroxylapatite (HAP) (test…
- Conditions
- Tooth Decay, Hydroxyapatite, Tooth Demineralization, Tooth Diseases
- Trial name
- ECIPDEN17 (NCT03553966)
- Testing
- Prophylactic, Cleaning teeth, Restorative dentistry
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Kurt Wolff GmbH & Co. KG
External Fixation Pin Site Infection
COMPARATIVE PROSPECTIVE STUDY OF COMPLICATIONS FOUND IN THE PINS OF EXTERNAL FIXERS COMPARING STEEL PINS AND PINS COATED WITH HYDROXIAPATITA
The present study is a prospective non-randomized and comparative study of patients undergoing surgical treatment with external fixators of any type, between May 2018 and May 2020, in the city of Passo Fundo, RS, Brazil, in the…
- Trial name
- NCT03649425
- Where
- Brazil
- Volunteers
- 119 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Primary Total Hip Arthroplasty
Clinical Observation Study of the Hydroxylapatite-coated SL-PLUS™ Hip Shaft
Summary from initial protocol Goal: Validation of the HA (hydroxylapatite) coated SL-PLUS™ stem within an observation study Study design: prospective, multicenter, observational, non-comparative study Study population: 240…
- Trial name
- SL-PLUS HA (NCT04121585)
- Testing
- Total Hip Arthroplasty
- Where
- 2 sites in Austria
- Volunteers
- 100 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Chitosan, Nano-hydroxyapatite Hydrogel
Chitosan Nano-hydroxyapatite Hydrogel in Non-Surgical Treatment of Intrabony Defect
The aim of this study was to evaluate the clinical effect of Chitosan with nano-hydroxyapatite hydrogel in the treatment of periodontal intrabony defects.
- Conditions
- Chitosan, Nano-hydroxyapatite Hydrogel, Intrabony Defect
- Trial name
- NCT06373757
- Testing
- Nano-HAP/Chitosan hydrogel
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- October 6 University
Orbital Implants
A Modified Orbital Implantation Technique in Enucleation
To assess the functional and cosmetic outcomes of enucleation with rectus end-to-end suturing surgical technique in hydroxyapatite orbital implants
- Trial name
- NCT01207713
- Volunteers
- 45 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Dental Implant Failed
Immediate Implant Placement With Provisionalization Using Different Bone Grafts as a Space Filling Material in the Maxillary Esthetic Zone
compare autogenous bone graft, xenograft and nanohydroxyapatite in immediate implant w placement in maxillary esthetic zone with provisionalization
- Trial name
- NCT03741036
- Testing
- Autogenous bone graft as space filling in immidiate implant placment, Deprotinized bovien as space filling in immidate implant placement, Nano-hydroxiapatite alloplast in immidiate implant placement
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mohamed tarek mohamed youssif omar
Edentulous
Buccal Plate Augmentation With Different Hydroxyapatite Based Material
The purposes of this study are : (first) to evaluate comparatively the effectiveness of 2 HA-based biomaterials when used for socket preservation with Buccal Plate Augmentation technique; (second) to evaluate clinical outcomes of…
- Trial name
- NCT01344577
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- University of Trieste
Gingival Recession, Generalized, Gingival Recession Generalized Moderate
Using Calcium Hydroxylapatite To Treat Gum Recession and Tooth Hypersensitivity
Study Purpose and Objectives: This study will utilize calcium hydroxylapatite (CaHA) to treat recession and hypersensitivity of the gums. The objectives of the study are: 1.
- Conditions
- Gingival Recession, Generalized, Gingival Recession Generalized Moderate, Gingival Recession Localized Moderate, Tooth Sensitivity
- Trial name
- NCT06826391
- Testing
- Calcium hydroxylapatite
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- American Academy of Facial Esthetics
Teeth Color, Teeth Staining
A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control
To determine whether brushing with a non-fluoride tooth whitening dentifrice containing nHAP and a high cleaning silica system produces a greater level of stain reduction as indicated by the Modified Lobene Stain Index (MLSI) for…
- Trial name
- NCT07214038
- Testing
- toothpaste
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Arthroplasty, Replacement, Hip
Omnifit Hydroxylapatite (HA) Hip Outcomes Study
The purpose of this study was to obtain up to 25 year post-operative data on the Omnifit Hydroxylapatite (HA) Hip System in support of the hypothesis that it is a satisfactory system for reducing implant loosening, permitting…
- Trial name
- NCT00958347
- Testing
- Omnifit HA Hip Stem
- Where
- 4 sites in United States, Netherlands
- Volunteers
- 226 people
- Sponsor
- Stryker Orthopaedics
Dental Caries, Periodontal Diseases
Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis
The aim of the study is to compare the incidence of dental caries and the level of demineralization in pediatric patients with asthma and/or allergic rhinitis. Patients will conduct professional oral hygiene at the baseline.
- Trial name
- NCT05631197
- Testing
- Biorepair Total Protection Plus + desensitizing enamel-repair shock treatment, Sensodyne Repair & Protect
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Marginal Integrity of Hydroxyapatite Nanofiber Reinforced Flowable Composite
Evaluation of Marginal Integrity of Hydroxyapatite Nano-Fiber Reinforced Flowable Composite Versus Conventional Resin-Based Flowable Composite in Initially Demineralized Pits and Fissure: A One Year, Randomized Clinical Trial
This study will be conducted to evaluate the Marginal integrity of Hydroxyapatite Nanofiber reinforced flowable composite compared to a conventional resin-based flowable composite during management of initial carious lesion in…
- Trial name
- NCT03242291
- Testing
- Conventional resin-based flowable composite, Hydroxyapatite Nanofiber reinforced flowable composite
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neurogenic Dysphonia, Neurogenic Dysphagia
Neurogenic Dysphonia/Dysphagia Registry
The Neurogenic Dysphonia/Dysphagia Registry is designed to be purely observational (i.e. non-interventional, exploratory). Patient data collected from the registry is expected to be consistent with any information which can be…
- Trial name
- StrongVoice (NCT02493491)
- Where
- 12 sites in United States
- Volunteers
- 146 people
- Sponsor
- Merz North America, Inc.