Clinical trials: Hot Flashes
Menopause, Menopausal Vasomotor Symptoms
Internet-Delivered CBT Program for Menopausal Vasomotor Symptoms
Given the impact that hot flashes and night sweats can have on daily life during the menopausal transition, our team has developed a therapist-guided online cognitive behavioural therapy (CBT)- based program to help individuals…
- Trial name
- ICBT-Meno-VS (NCT07873177)
- Testing
- Internet-delivered Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Postmenopausal Flushing, Postmenopausal Symptoms
Self-Management Box on Hot Flash in Postmenopausal Women
Aim of the study This study aims to evaluate the effect of a nurse-led menopause self-management box on hot flash frequency and menopause-specific quality of life among postmenopausal women.
- Trial name
- Self-Managemen (NCT07874893)
- Testing
- Components of Nurse-Led Menopause Self- Management Box
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Perimenopause, Postmenopause
Effects of a Dietary Supplement in Women With Late Perimenopause or Early Postmenopause
This study will evaluate the effects of a plant extract-based dietary supplement on menopausal symptoms and health indicators in women with late perimenopause or early postmenopause.
- Conditions
- Perimenopause, Postmenopause, Hot Flashes
- Trial name
- NCT07863973
- Testing
- Plant Extract-Based Dietary Supplement
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Vasomotor Symptoms
Safety and Efficacy of Asimadoline (TP0052) in Patients With Vasomotor Symptoms (VMS).
This Phase 2a randomized, double-blind, placebo-controlled study evaluates the safety and efficacy of asimadoline (TP0052), a peripherally restricted selective kappa-opioid receptor agonist, for moderate to severe menopausal…
- Trial name
- NCT07042516
- Testing
- Asimadoline
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Tioga Pharmaceuticals
Obesity, Menopause Hot Flashes
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
The purpose of this study is to determine the effect of tirzepatide on vasomotor symptoms and on measures of biological aging.
- Trial name
- NCT07218445
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Menopause
Satavari and Ashoka for Menopause (SAM) Study
This 12-week randomized, placebo-controlled clinical trial will evaluate the efficacy and safety of a daily oral supplement containing Ashoka Bark and Shatavari in women experiencing menopausal symptoms.
- Trial name
- SAM (NCT07861295)
- Testing
- Ashoka Bark and Shatavari
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vidya USA Corporation
Breast Cancer Female
Guided Digital Self-Hypnosis Solution for Managing Hot Flashes in Patients Undergoing Adjuvant Hormone Therapy
Patients treated for breast cancer with hormone therapy (HT) suffer from hot flashes. This side effect impacts treatment adherence.
- Trial name
- HYBOU (NCT06552091)
- Testing
- self-hypnosis sessions
- Where
- France
- Volunteers
- 76 people
- Sponsor
- Institut de Cancérologie de Lorraine
Menopause, Menopause Hot Flashes
Effects of a Dietary Intervention Based on the Dietary Guidelines for the Brazilian Population on the Reduction of Menopausal Symptoms in Overweight and Obese Women
The menopausal transition is associated with significant hormonal changes that negatively impact many women's quality of life. Vasomotor symptoms, sleep disturbances, mood changes, and genitourinary symptoms are frequently…
- Conditions
- Menopause, Menopause Hot Flashes, Overweight , Obesity, Perimenopause, Climacteric Syndrome
- Trial name
- NCT07822230
- Testing
- Nutritional guidelines on healthy eating based on the Dietary Guidelines for the Brazilian Population in printed material and 5 in-person and virtual meetings, Nutritional guidelines on healthy eating based on the Dietary Guidelines for the Brazilian Population only in printed material
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Hot Flashes
A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause
This study is for women in India who are going through menopause. They have symptoms including hot flashes and night sweats (also known as vasomotor symptoms or VMS).
- Trial name
- NCT07829653
- Testing
- Fezolinetant
- Volunteers
- 100 people
- Sponsor
- Astellas Pharma Inc
Prostate Cancer, Hot Flashes
Reduce HEAT: A Randomized Trial of Wearable Thermal Devices for ADT-Induced Hot Flashes
This is a prospective, randomized, non-pharmacologic interventional trial evaluating the effectiveness of the Embr Wave wearable thermal device in reducing hot flash burden in men with prostate cancer receiving androgen…
- Conditions
- Prostate Cancer, Hot Flashes, Vasomotor Symptoms
- Trial name
- ReduceHEAT (NCT07729150)
- Testing
- Embr Wave
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer, Menopausal Symptoms
Effect of a Brassicaceae-Enriched Diet on Menopausal Symptoms in Women With Breast Cancer Receiving Antiestrogen Therapy
This study aims to evaluate whether increasing the intake of Brassicaceae vegetables may help reduce menopausal symptoms in women with hormone-sensitive breast cancer who are receiving adjuvant antiestrogen therapy.
- Trial name
- BRASSICA (NCT07842614)
- Testing
- Increased Dietary Intake of Brassicaceae Vegetables
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
THERAPY-INDUCED HOT FLASHES IN BREAST CANCER PATIENTS
Role of Folic Acid in the Management of Adjuvant Endocrine Therapy-Induced Hot Flashes in Breast Cancer Patients
The study aims to assess the efficacy of folic acid supplementation at two doses (1 mg/day and 5 mg/day) in the management of hot flashes associated with adjuvant endocrine therapy among premenopausal breast cancer patients.
- Trial name
- NCT06774885
- Testing
- Folic Acid 1 Mg Oral Tablet, Folic Acid 5 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Future University in Egypt
Hot Flashes
A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy
One of the standard treatments for women with breast cancer is hormone therapy, but this treatment can cause hot flashes. Hormone replacement therapy, or HRT, is most often prescribed for hot flashes for women in menopause but…
- Trial name
- NCT06440967
- Testing
- Fezolinetant, Tamoxifen, Aromatase inhibitor
- Where
- 110 sites in Canada, Czechia and 9 more
- Volunteers
- 982 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Menopause, Hot Flashes
Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)
This study will evaluate whether an 8-week course of a standardized herbal extract containing Shatavari and natural bio-enhancer ingredients can reduce menopausal symptoms in post-menopausal women.
- Trial name
- RENEW (NCT07834463)
- Testing
- Shatavari (Asparagus racemosus) Extract
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- India Glycols Ltd
Menopause Hot Flashes
Thermoregulatory Physiology of Menopausal Hot Flashes
This study is evaluating the effects of cooling on menopausal hot flashes in midlife women. Precise targeted cooling is provided to areas of the skin when a hot flash occurs.
- Trial name
- NCT07824648
- Testing
- Intervention C (Targeted skin cooling), Intervention B (Ambient cooling), Intervention A (Room temperature)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- SRI International
Menopause, Menopause Hot Flashes
Haelan 951 for Menopause Symptoms in Peri- and Postmenopausal Women
This proof-of-concept, open-label, single-arm study is designed to evaluate the effects of daily consumption of Haelan 951, a fermented soy conventional food product, on self-reported menopausal vasomotor symptoms, sleep quality…
- Conditions
- Menopause, Menopause Hot Flashes, Menopause Related Conditions
- Trial name
- H951-MENO (NCT07751029)
- Testing
- Haelan 951
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Spectrum Clinical Research, LLC
Menopause Hot Flashes
Fezolinetant and Vascular Health and Brain Health
The goal of this clinical trial is to learn whether a study drug called fezolinetant impacts cardiovascular and cognitive health in women who have moderate to severe menopausal hot flashes and night sweats.
- Trial name
- FAVES-B (NCT07606664)
- Testing
- Fezolinetant
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rebecca Thurston
Accupuncture, Prostate Cancer
Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy
This study is evaluating whether acupuncture may help reduce hot flashes in men receiving hormone therapy for prostate cancer. Hot flashes are a common side effect of androgen deprivation therapy (ADT) and may negatively affect…
- Conditions
- Accupuncture, Prostate Cancer, Hormone Therapy, Hot Flashes
- Trial name
- NCT07594002
- Testing
- Real Acupuncture
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kentucky
Vasomotor Symptoms
Goji Berry and Vasomotor Symptoms Pilot Study
The goal of this clinical trial is to compare two forms of goji berry powder-whole goji berry powder and goji juice powder-in peri- and postmenopausal women aged 40-65 years who experience frequent vasomotor symptoms (hot…
- Trial name
- GOJI-VMS (NCT07660315)
- Testing
- Goji Berry Juice Powder, Goji Berry Powder
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Prostate Cancer, Prostate Cancer (Adenocarcinoma)
Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
The goal of this clinical trial is to learn if fezolinetant can treat hot flashes (vasomotor symptoms) in men with prostate cancer undergoing androgen deprivation therapy.
- Conditions
- Prostate Cancer, Prostate Cancer (Adenocarcinoma), Prostate Cancer Metastatic Disease, Prostate Cancer Recurrent
- Trial name
- Fezo-ADT (NCT06957691)
- Testing
- fezolinetant - reference formulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shehzad Basaria, M.D.