Clinical trials: Home Mechanical Ventilation
Copd, COPD Exacerbation
Change in Breathing Pattern on Non-invasive Ventilation of COPD Patients Under Home Mechanical Ventilation
Acute exacerbation of COPD (AECOPD) worsen prognosis and quality of life of COPD patients. Telemonitoring could be a useful tool for early identification of AECOPD. Parameters that have to be monitored are not well defined.
- Trial name
- NCT03018470
- Testing
- Analysis of data from NIV built-in software
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Rouen
Neuromuscular Diseases, Obesity Hypoventilation Syndrome
Effectiveness Monitoring of Home Non-invasive Mechanical Ventilation by Digital Diagnosis Platform
The main objective will be to determine the effectiveness of home non-invasive ventilation by flow-time and time-pressure curves analysis in a cohort of patients with this treatment by digital diagnosis platform.
- Conditions
- Neuromuscular Diseases, Obesity Hypoventilation Syndrome, Lung Disease, Restrictive
- Trial name
- PRE-HVNI (NCT03085537)
- Where
- 3 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Corporacion Parc Tauli
Nutrition
Individualized Metabolic Assessment and Nutritional Optimization in Children With Chronic Respiratory Insufficiency
The investigators aim to examine the feasibility of individualized diet intervention in children dependent on long-term mechanical ventilator support at home.
- Trial name
- NutriCAPE (NCT02354495)
- Testing
- Changes in energy and protein intake
- Volunteers
- 16 people
- Sponsor
- Boston Children's Hospital
COPD Exacerbation
HOT HMV 2: A Phase 4 Study
Smoking related lung disease or Chronic Obstructive Pulmonary Disease (COPD) is characterised by periods of worsening symptoms termed exacerbations.
- Trial name
- HOT-HMV2 (NCT04272879)
- Testing
- Observational Group
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Amyotrophic Lateral Sclerosis
Ambulatory Versus Inpatient Initiation of Home Mechanical Ventilation
The purpose of this investigation is to see if outpatient initiation of noninvasive home mechanical ventilation combined with closed telemonitoring and follow-up in patients with amyotrophic lateral sclerosis is non-inferior to…
- Trial name
- NCT05829330
- Testing
- Outpatient, Hospitalization
- Where
- Denmark
- Volunteers
- 46 people
- Sponsor
- Anne Kathrine Staehr-Rye
Heart, Respiratory, Disease, Functional
Natural History of Cardiac and Respiration Function in Patients With Muscular Dystrophies on Home Mechanical Ventilation
Muscular dystrophies are inherited disorders that affect skeletal muscle. Cardiac and respiratory function may be affected in this group of diseases.
- Trial name
- NCT02501083
- Testing
- no intervention
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Pulmonary Disease, Chronic Obstructive, Amyotrophic Lateral Sclerosis
European Home Mechanical Ventilation Registry
The European Home Mechanical Ventilation Registry (EHMVR) will enable a thorough evaluation of HMV by documenting the characteristics of HMV patients and their treatment.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Amyotrophic Lateral Sclerosis, Spinal Cord Injury, Muscular Dystrophies
- Trial name
- EHMVR (NCT02315339)
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- ResMed
Respiratory Failure, Long-term Non-invasive Ventilation
Ventilator-associated Injury (VAI) in Chronic Home Mechanical Ventilation
Rationale: The pathophysiological changes in respiratory muscle morphology and functioning in patients with end-stage pulmonary disease are not very well known.
- Trial name
- NCT04521426
- Testing
- No other than standard care
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Neuromuscular Disease
Long-Term Effect of LIAM on Respiratory Performance in NIV Patients Suffering From Neuromuscular Disease
The long-term effect of LIAM (Lung Insufflation Assist Maneuver) on respiratory performance in home non-invasively ventilated (NIV) patients suffering from neuromuscular disease will be assessed in a prospective, randomized…
- Trial name
- LIAM (NCT02288299)
- Testing
- non invasive mechanical ventilation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Chronic Obstructive Pulmonary Disease
A40 Expiratory Flow Limitation Registry
This prospective observational multicenter registry study will include adults greater than 40 years old, diagnosed with chronic obstructive pulmonary disease, requiring home noninvasive ventilation as part of standard medical…
- Trial name
- NCT04419428
- Testing
- BiPAP A40 Expiratory Flow Limitation (EFL)
- Where
- United Kingdom
- Sponsor
- Philips Clinical & Medical Affairs Global
Asthma, Pollution; Exposure
Residential Ventilation Systems and Filtration for Asthma Control in Adults
The goal of this study was to investigate the effectiveness of three common approaches to upgrading residential mechanical ventilation systems in existing homes for improving asthma-related health outcomes, reducing indoor…
- Trial name
- NCT06098287
- Testing
- Residential mechanical ventilation system (Exhaust), Residential mechanical ventilation system (CFIS) and air filtration upgrades, Residential mechanical ventilation system (ERV) and air filtration upgrades
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Illinois Institute of Technology
Neuromuscular Diseases
Polygraphy at Home for Neuromuscular Patients Under Non-invasive Mechanical Ventilation
The primary objective of the study is to evaluate the feasibility, the quality and the utility of a polygraphic control at home in order to appreciate the efficacy of the night time non-invasive ventilation (allowing to optimize…
- Trial name
- HPforNIV (NCT05785637)
- Testing
- Polygraphy diagnostic at home
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Home Mechanical Ventilation, Neuromuscular Disease
Prognostic Value of Residual Hypoventilation in Mechanically Ventilated Neuromuscular Patients
Different tools may be used to monitor the efficacy of home mechanical ventilation. Investigators aimed to compare the prognostic value of the different data obtained by capno-oxymetry in a mechanical ventilated neuromuscular…
- Trial name
- TcCO2-VAD (NCT02551406)
- Testing
- Capno-oxymetry monitoring
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Respiratory Failure
Last 3 Months of Life in Home Ventilated Patients
To verify with a specific questionnaire, the families' perceived quality of end-of-life care and of dying in the last 3 months of life of 168 patients (Chronic Obstructive Pulmonary Disease-Amyotrophic Lateral Sclerosis…
- Trial name
- NCT00553046
- Testing
- survey administration
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Fondazione Salvatore Maugeri
Chronic Obstructive Pulmonary Disease
Home Mechanical Ventilation vs Home Oxygen Therapy in COPD
This study is designed to investigate the effect of home mechanical ventilation (HMV) in patients with severe chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00990132
- Testing
- Home mechanical ventilation, Long term oxygen therapy
- Where
- 7 sites in United Kingdom
- Volunteers
- 116 people
- Sponsor
- Patrick Murphy
Non Invasive Ventilation
Telemonitoring Utility in the Process of Adaptation to Home Mechanical Ventilation (HMV)
The goal of this clinical trial is to evaluate whether telemonitoring, added to the usual process of adaptation to home mechanical ventilation (HMV), achieves a more efficient correction of hypoventilation (reduction of…
- Trial name
- NCT06240637
- Testing
- Telemonitoring
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Ventilatory Failure
Tele-monitoring of Patients With Home Mechanical Ventilation (HMV) Trough Telemedicine System (MyVENT)
The purpose of this study is to improve HMV treatment adherence using an integrated telemedicine platform (MyVENT system)
- Trial name
- MyVENT (NCT03971630)
- Testing
- Telemedicine
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Mechanical Ventilation
Quality Control of Home Mechanical Ventilators
A multicentre quality control survey of home mechanical ventilation in patients. The prescribed ventilation settings, the settings of the ventilator control panel and the actual performance of the ventilator will be tested.
- Trial name
- NCT03854968
- Testing
- Quality control
- Where
- Spain
- Volunteers
- 147 people
- Sponsor
- Hospital Clinic of Barcelona
Respiratory Insufficiency Requiring Mechanical Ventilation
Telemonitoring in Home Mechanical Ventilation
Multicentric, observational and longitudinal prospective evaluation of build-in-software data telemonitoring of home ventilators in patients using Home Mechanical Ventilation in Belgium.
- Trial name
- NCT06143384
- Testing
- Telemonitoring AirView (ResMed company)
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Neuromuscular Diseases (NMD), ALS (Amyotrophic Lateral Sclerosis)
Invasive Home Ventilation in Denmark
The aim of this study is to describe national trends over the past 10 years in patients receiving invasive home mechanical ventilation (HMV) in Denmark.
- Conditions
- Neuromuscular Diseases (NMD), ALS (Amyotrophic Lateral Sclerosis), Spinal Cord Injuries (SCI), Duchenne Muscular Dystrophy (DMD)
- Trial name
- HOMEVENT DK (NCT07467187)
- Where
- Denmark
- Volunteers
- 450 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet