Clinical trials: Hip Fracture Surgery
Femur Fracture, Periprosthetic Fracture of Hip
Dose-Response Association Between Cerclage Wire Number and Infection Risk
The purpose of this dual-center retrospective study is to investigate the relationship between the number of metallic cerclage wires used in femoral fracture surgery and the risk of developing deep infections.
- Conditions
- Femur Fracture, Periprosthetic Fracture of Hip, Periprosthetic Fracture of the Femur, Surgical Site Infection (SSI)
- Trial name
- C-INFECT (NCT07434258)
- Testing
- 1 Metallic Cerclage Wiring, 2 metalic cerclage wire, 3 metalic cerclage wire
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Delirium - Postoperative, Hip Fracture Surgeries
DEX-HIP Trial: Preoperative IV Dexamethasone 4 mg vs Placebo to Reduce Postoperative Delirium Burden in Adults ≥70 Undergoing Hip Fracture Surgery
This single-center, prospective, randomized, double-blind, placebo-controlled trial was conducted at the Department of Orthopaedic Surgery, JPMC, Karachi.
- Conditions
- Delirium - Postoperative, Hip Fracture Surgeries, Steroid
- Trial name
- NCT07651150
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Femoral Neck Fractures, Nerve Block
Lumbar-Sacral Plexus Block vs Fascia Iliaca Block Plus Low-Dose Spinal Anesthesia for Femoral Neck Fracture Surgery
Femoral neck fracture surgery in elderly patients is frequently complicated by intraoperative hypotension and inadequate postoperative analgesia.
- Trial name
- NCT07346885
- Testing
- Lumbar and Sacral Plexus Block, Fascia Iliaca Block Combined with Low-Dose Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Neuromuscular Blockade, Arthroplasty, Replacement, Hip
Reversal of Neuromuscular Blockade With Sugammadex or Usual Care in Hip Fracture Surgery or Joint (Hip/Knee) Replacement (P07038)
This study will assess the effect of reversal of neuromuscular blockade with sugammadex compared with reversal according to usual care (neostigmine or spontaneous reversal) on the incidence of post-surgical bleeding events and on…
- Conditions
- Neuromuscular Blockade, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Blood Coagulation
- Trial name
- NCT01422304
- Testing
- Sugammadex, neostigmine and glycopyrrolate or atropine
- Volunteers
- 1,198 people
- Sponsor
- Merck Sharp & Dohme LLC
Femoral Neck Fractures
Comparison of the Direct Anterior Approach (DAA) and the Direct Lateral Approach (DLA) in Patients Treated With Partial Hip Replacement for Femoral Neck Fracture Based on Postoperative Functional Status
The goal of this clinical trial is to learn whether the surgical approach used for hemiarthroplasty can improve clinical and functional outcomes in adults with displaced femoral neck fractures.
- Trial name
- NCT07501741
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Hip Fractures
Comparative Study to Evaluate the Efficacy of Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Versus Fascia Iliaca Compartment (FIC) Block on the Postoperative Analgesic Effect in Patients Undergoing Hip Surgeries Under Spinal Anesthesia.
Fractures in and around the hip are quite common irrespective of both the young and elderly population groups and are associated with extreme pain.
- Trial name
- NCT05751291
- Testing
- Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sohag University
Inflammatory Response, Anesthesia
Effect of Peng Block Application on Inflammation and Mortality in Hip Fractures
In this study, the investigators the effect of PENG block on SIRI (systemic inflammation response index) and 30-day mortality in geriatric patients(over 65 years old) undergoing hip surgery, and the effect on the length of…
- Conditions
- Inflammatory Response, Anesthesia, Hip Fractures
- Trial name
- NCT06795724
- Testing
- PENG block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Hip Fracture, Anemia
IV Iron in Association With Tranexamic Acid for Hip Fracture
It is a prospective randomized controlled study aiming to test if tranexamic acid combined to intravenous iron before and after surgery for hip fracture in elderly can decrease peri-operative red cell transfusion.
- Trial name
- NCT02428868
- Testing
- tranexamic acid (Exacyl®), intravenous iron (Ferroven®), Saline
- Where
- Tunisia
- Volunteers
- 150 people
- Sponsor
- Institut Kassab d'Orthopédie
Hip Fractures, Anemia
The Effect of Preoperative Ferric Carboxymaltose Administration on Mortality in Geriatric Hip Fractures
Hip fractures (HF) are the most common and serious pathology affecting the hip and are associated with a high mortality risk in elderly patients.
- Conditions
- Hip Fractures, Anemia, Complication,Postoperative
- Trial name
- NCT06080893
- Testing
- Ferric carboxymaltose
- Where
- Turkey (Türkiye)
- Volunteers
- 209 people
- Sponsor
- Istanbul University
Pelvic Fracture, Urethra Tear
Primary Urethral Realignment Versus Suprapubic Cystostomy After Pelvic Fracture Urethral Injury
Pelvic fracture urethral injuries (PFUI) occur in up to 10% of pelvic fractures. It remains controversial whether initial urethral realignment after PFUI decreases rates of urethral obstruction and the need for subsequent…
- Conditions
- Pelvic Fracture, Urethra Tear, Urethra Injury Male, Trauma
- Trial name
- NCT03195179
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Hip Fracture, Perioperative Myocardial Injury
Nerve Block and Perioperative Myocardial Injury in Elderly Hip Fracture
This single-center, retrospective cohort study evaluates whether a single preoperative peripheral nerve block can reduce the risk of perioperative myocardial injury in elderly patients undergoing delayed hip fracture surgery…
- Conditions
- Hip Fracture, Perioperative Myocardial Injury, Myocardial Injury After Noncardiac Surgery
- Trial name
- PNB-CARD (NCT07751146)
- Testing
- PNB, Non-PNB
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Hip Fracture, Elderly Patients
Hope Theory-Based Nursing Intervention After Hip Fracture Surgery
This is a randomized controlled trial to evaluate the effectiveness of a Snyder Hope Theory-based nursing intervention on elderly patients following hip fracture surgery.
- Conditions
- Hip Fracture, Elderly Patients, Postoperative Recovery, Nursing Interventions
- Trial name
- NCT07400770
- Testing
- Snyder Hope Theory-based Nursing Intervention, Standard Postoperative Care
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Institute of Orthopaedic Surgery, Taizhou No.3 People's Hospital
Delirium, Hip Fracture
Evaluating the Addition of Regional Analgesia to Reduce Postoperative Delirium in Patients Having Hip Fracture Surgery.
Post operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and increased mortality.
- Trial name
- RASAPOD (NCT02689388)
- Testing
- Femoral Nerve Block
- Where
- New Zealand
- Volunteers
- 20 people
- Sponsor
- Auckland City Hospital
Hip Fractures, Hemodynamic Stability
Hemodynamic Safety of Levobupivacaine vs Bupivacaine in Patients Over 65 Years Undergoing Hip Surgery
The altered hemodynamics, and therefore the arterial hypotension is the most prevalent adverse effect after subarachnoid anesthesia.
- Trial name
- NCT03843970
- Testing
- Levobupivacaine Hydrochloride 0.5%, Isobaric bupivacaine 0.5%
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital Clínico Universitario de Valencia
Pelvic Fracture
Pelvic Fractures in the Elderly
The aim of the project is to predict the patient under conservative therapy as a function of the patient Classification of Rommens and Hofmann and other potential prognostic factors.
- Trial name
- PelvFx (NCT03476824)
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Hip Fracture, Blood Loss
Can Thrombelastography Predict Blood Loss in Patients With Hip Fractures
Hip fractures are associated with a large hidden blood loss. That is, the total blood loss associated with hip fracture surgery is much greater than that observed intra operatively.
- Trial name
- NCT02297061
- Testing
- Thrombelastography analysis (TEG)
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Hvidovre University Hospital
Geriatric Hip Fracture Pain Management
Pain Management in Geriatric Hip Fracture
The Null Hypothesis is that there is no association between Pain regime and the functional performance among geriatric patients having traumatic hip fracture. Two limbs are being assessed:1.
- Trial name
- NCT01630343
- Testing
- Paracetamol tablet and Tramadol capsule, Panadol 500mg tablet, tramadol 50mg capsule
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Femoral Neck Fracture
Ropivacaine Hypobaric Spinal Anaesthesia in Traumatic Hip Surgery
This is a prospective, monocentric, randomized study, comparing the effectiveness and tolerance of four different dosages of hypobaric ropivacaine for unilateral spinal anaesthesia during traumatic femoral neck surgery in the…
- Trial name
- NCT01005550
- Testing
- 6 mg of ropivacaine, 8 mg of ropivacaine, 10 mg of ropivacaine
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Fractures, Hip, Femoral Neck Fractures
Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures
The goal of this clinical trial is to explore the effects of different peripheral nerve blocks in older adults with hip fractures. It will also explore the safety of preoperative administration of peripheral nerve blocks.
- Conditions
- Fractures, Hip, Femoral Neck Fractures, Intertrochanteric Fractures, Subtrochanteric Fractures
- Trial name
- NCT07130006
- Testing
- PENG and LFCN peripheral nerve blocks with spinal anesthesia, FN and LFCN peripheral nerve blocks with spinal anesthesia, FIC peripheral nerve block with spinal anesthesia
- Where
- Croatia
- Volunteers
- 256 people
- Sponsor
- University Hospital of Split
Retinal Imaging
Hand-held Optical Coherence Tomography Feasibility Older Hip Fracture
Assessment of the feasibility of achieving retinal imaging in older people with recent hips fracture surgery using hand held optical coherence tomography device
- Trial name
- NCT04041336
- Testing
- Optical coherence tomography
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham