Clinical trials: Hip Fracture
Hip Arthroplasty, Total, Postoperative Pain
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Pain After Hip Surgery
Pain after hip replacement surgery is often severe and is commonly treated with opioids, which may cause nausea, vomiting, sedation, difficulty passing urine and slow breathing.
- Conditions
- Hip Arthroplasty, Total, Postoperative Pain, Hip Arthroplasty, Analgesia
- Trial name
- NCT07784192
- Testing
- Morpine, Ultrasound-guided pericapsular nerve group block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Selcuk University
Hip Arthroscopy, Articular Cartilage Defect
AMIC Compared With Microfracture for Focal Articular Cartilage Damage of the Hip
This is a pilot multi-centre RCT of 40 patients (ages 18-55 years, inclusive) undergoing primary hip arthroscopy with a focal articular cartilage defect of the acetabulum to compare the effect of using autologous matrix-induced…
- Conditions
- Hip Arthroscopy, Articular Cartilage Defect, Microfractures
- Trial name
- REPAIR (NCT05402072)
- Testing
- Autologous matrix-induced chondrogenesis (AMIC)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McMaster University
Femoral Neck Fractures
MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)
This study is an intervention domain of the Musculoskeletal Adaptive Platform Trial. The primary goal of this pragmatic, randomized, open-label, comparative effectiveness trial is to evaluate if arthroplasty is superior to…
- Trial name
- FASTER-HIP (NCT07244211)
- Testing
- Hip arthroplasty, Internal fixation
- Where
- 31 sites in United States, Canada and 3 more
- Volunteers
- 600 people
- Sponsor
- University of Southern California
Hip Fractures, Frailty
AI-Supported Physiotherapy After Hip Fracture in Frail Older Adults
Purpose Hip fractures in older adults often cause a serious loss of strength and independence. Physical therapy helps people recover, but patients do not always exercise consistently or correctly.
- Trial name
- Fisio-ACTIVA (NCT07857707)
- Testing
- Conventional hospital physiotherapy, Automated motivational support and movement-capture system
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Fractures, Hip, Local Anesthesia
Influence of Peri-operative Anesthetic and Analgesic Care on the Outcome of Patients Undergoing Hip Fracture Surgeries. A Prospective Study
The purpose of this voluntary research study is to clarify whether or not a single injection nerve block done before surgery and after surgery nerve block catheter can effectively enhance recovery in elderly hip fracture patients…
- Conditions
- Fractures, Hip, Local Anesthesia, Geriatric, Nerve Block
- Trial name
- NCT06925789
- Testing
- Ropivacaine
- Sponsor
- Milton S. Hershey Medical Center
Delirium - Postoperative
Effects of PNB Timing on Postoperative Delirium for Hip Fracture
Hip fracture is a common cause of hospitalization in older adults and is associated with substantial pain and a high risk of delirium.
- Trial name
- NCT07856108
- Testing
- Peripheral Nerve Block for Hip Fracture
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hip Osteoarthritis, Hip Disease
MDR - G7 Neutral and G7 Freedom Constrained Neutral Acetabular Liners
The objective of this consecutive series PMCF study is to collect data confirming safety, performance and clinical benefits of the G7 Freedom Constrained Liners when used for primary and revision total hip arthroplasty (implants…
- Conditions
- Hip Osteoarthritis, Hip Disease, Hip Fractures, Hip Injuries
- Trial name
- NCT04093739
- Testing
- G7 Freedom Constrained Liners
- Sponsor
- Zimmer Biomet
Postoperative Delirium, Hip Fracture Surgery
Cytokines, POD, Health Status, Older Hip Fracture
An investigation of the change in inflammation marker levels across hip fracture surgery and an exploration of any association with change in self reported health status and incidence of postoperative delirium
- Conditions
- Postoperative Delirium, Hip Fracture Surgery, Older People
- Trial name
- NCT05096507
- Testing
- Hip fracture Surgery (Primary)
- Where
- United Kingdom
- Volunteers
- 49 people
- Sponsor
- University of Nottingham
PENG Block, Hip Fracture Surgeries
Comparison of Femoral Nerve Block and Combined PENG Plus Femoral Nerve Block in Geriatric Hip Surgery
Hip fracture surgery in geriatric patients is frequently associated with severe perioperative pain, which may complicate positioning for spinal anesthesia and increase perioperative opioid requirements.
- Trial name
- PENG-FEM (NCT07350044)
- Testing
- Pericapsular nerve group (PENG) block plus femoral nerve block, Femoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara City Hospital Bilkent
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)
Cohort Study on the Prognosis and Influencing Factors in Elderly Patients With Hip Fractures in Multicenter of China
To address the difficulties and problems currently facing large-scale clinical cohort studies in China, and on the basis of the existing project "Construction of Clinical Registration Database and Risk Assessment System for…
- Trial name
- NCT07847164
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Hospital
Cervical Myelopathy, Hip Fractures
Cervical Myelopathy in Hip Fracture Patients
Recent evidence has demonstrated a high rate of undiagnosed cervical myelopathy in patients presenting with hip fractures from a ground level fall.
- Trial name
- NCT06893406
- Testing
- Cervical MRI, History & Physical Exam
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Proximal Femoral Fractures
Incidence of Cut-out Using Intramedullary Nails With Double Cephalic Screw vs. Unique in Pertrochanteric Fractures
The goal of this clinical trial is to compare outcomes in the treatment of proximal femur fractures. The main question it aims to answer is whether the use of a double cephalic screw prevents nail failure (cut-out).
- Trial name
- NCT06293495
- Testing
- Gamma 3 Nail (Stryker), Chimaera Nail (Orthofix)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Puerta de Hierro University Hospital
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Pain, Hip Fracture
PENG vs. FIC Block for Hip Fracture ED Patients
Ultrasound-guided nerve blocks are an important tool for treating pain due to orthopedic injury in the ED. They provide long lasting, opioid-sparing pain relief that is generally safe and well-tolerated by patients1.
- Trial name
- NCT05102760
- Testing
- Nerve Block using FIC Proceedure, Nerve Block using PENG Proceedure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Antonios Likourezos
Hip Fractures, Venous Thromboembolism (VTE)
Delivery and Implementation of a Randomised Crossover Trial on Thrombosis
What is the Study About? The DIRECT study (Delivery and Implementation of a Randomised Crossover Trial on Thrombosis) is a large research project investigating the best way to prevent blood clots (thrombosis) in people who break…
- Trial name
- DIRECT (NCT06937372)
- Testing
- Patients in hospitals allocated to this arm will receive aspirin as their routine thromboprophylaxis after surgery., Low molecular weight heparin (LMWH)
- Where
- United Kingdom
- Volunteers
- 21,194 people
- Sponsor
- Queen Mary University of London
Hip Fractures, Arthroplasty, Replacement, Hip
PENG Block + LIA For Endoprosthesis Surgery
The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery.
- Conditions
- Hip Fractures, Arthroplasty, Replacement, Hip, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- PENG 360° (NCT07239817)
- Testing
- Pericapsular Nerve Group Blocks with Local Infiltration Analgesia, spinal anesthesia
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Gaetano Pini-CTO
Healthy, Osteopenia
Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-BMD (NCT07187518)
- Testing
- Measurements with the POROUS R4C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine
- Where
- 2 sites in Germany
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Osteoarthritis, Hip, Femur Head Necrosis
Clinical Outcomes of Primary Cementless Total Hip Arthroplasty Using the Collarless Actis Stem
This study looks at how well a hip replacement using the collarless Actis stem works over five years. Total hip replacement is a common operation for people whose hip joint has been damaged by arthritis, by loss of blood supply…
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Femoral Neck Fractures, Arthritis Rheumatoid
- Trial name
- NCT07828080
- Testing
- Collarless Actis femoral stem
- Where
- South Korea
- Volunteers
- 210 people
- Sponsor
- Seoul National University Bundang Hospital
Hip Fracture, Pain Management
Comparison of the Efficacy of Ultrasound-guided Supra-inguinal Fascia Iliaca and Lumbar Erector Spina Plan Block in Hip Fractures
The aim of our study was to evaluate the efficacy and patient satisfaction level of SI-FIB and lumbar ESPB for positioning and postoperative analgesia during spinal anesthesia in patients undergoing hip fracture surgery.
- Conditions
- Hip Fracture, Pain Management, Multimodal Analgesia, Peripheral Nerve Block
- Trial name
- NCT07639762
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Hip Fractures, Pain, Postoperative
The Effect of TENS on Pain and Analgesic Consumption
The surgical treatment of an individual with osteoarthritis and hip fracture is provided by hip replacement surgery. While restructuring the joint surfaces with surgery, it is aimed to provide both hip joint movements and to…
- Conditions
- Hip Fractures, Pain, Postoperative, Analgesia
- Trial name
- NCT05939804
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University