Clinical trials: High Risk of Stroke
Intracranial Atherosclerosis, Stent Stenosis
Elucidate Outcomes of Elective High-grade/Total Occlusion Intracranial Arteries Using Low-profile Self-expanding Stent
Intracranial atherosclerotic disease (ICAD) is a high prevalent cause of stroke, especially in Asian population and can be categorized as either symptomatic (resulting in acute ischemic stroke) or asymptomatic.
- Conditions
- Intracranial Atherosclerosis, Stent Stenosis, Ischemic Stroke
- Trial name
- NCT05947994
- Testing
- Intracranial stenting with Credo® stent
- Where
- Vietnam
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Can Tho Stroke International Services Hospital
Intracerebral Hemorrhage, CAA - Cerebral Amyloid Angiopathy
MRI-markers to Monitor Small Vessel Disease Dynamics in the Prognosis of Small Vessel Disease-associated, Cerebrovascular Events
This is a nested cohort study in the PRO-SVD cohort. Small vessel disease is a chronic disease and is thought to progress over time.
- Conditions
- Intracerebral Hemorrhage, CAA - Cerebral Amyloid Angiopathy, Cerebral Small Vessel Diseases
- Trial name
- MRI-PRO-SVD (NCT05773235)
- Testing
- Combined 3- and 7 Tesla-MRI
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Respiratory Insufficiency, Pulmonary Disease, Chronic Obstructive
The Effect of Aromatherapy Massage on Pain, Anxiety and Comfort
Patients in the intensive care unit (ICU) experience physical and psychological discomfort, including pain. Anxiety is a condition frequently encountered in the ICU.
- Conditions
- Respiratory Insufficiency, Pulmonary Disease, Chronic Obstructive, Diabetes Mellitus, Type 2, High Blood Pressure
- Trial name
- NCT06295874
- Testing
- Effect of aromatherapy massage on vital signs, pain, anxiety and comfort level
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Nilgün Erdoğan
Plaque, Atherosclerotic Disease
BioImage Study: A Clinical Study of Burden of Atherosclerotic Disease in an At-Risk Population
The BioImage Study is a study of the characteristics of subclinical cardiovascular disease, as measured by imaging modalities, unsupervised circulating biomarker measurements, and risk factors that predict progression to overt…
- Conditions
- Plaque, Atherosclerotic Disease, Heart Disease, Stroke
- Trial name
- NCT00738725
- Where
- 2 sites in United States
- Volunteers
- 7,687 people, healthy volunteers welcome
- Sponsor
- BG Medicine, Inc
Stroke
High-definition Transcranial Electrical Stimulation for Upper Extremity Rehabilitation
Upper limb hemiparesis is the most common sequelae in patients, severely impacting their independence and quality of life. Transcranial electrical stimulation (tCES) is a non-invasive and safe treatment, which uses a low direct…
- Trial name
- NCT06409143
- Testing
- HD-tES, UE rehabilitation, HD-tES (Bilateral)
- Where
- 3 sites in Taiwan
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Oneida Nation Members
The AHA Oneida Study
The purpose of this clinical trial is to learn whether a cultural nutritional program can change stroke risk factors, cognitive decline, and learn how school education programs about nutrition can improve health in the Oneida…
- Trial name
- NCT07139132
- Testing
- Health Wellness Coaching, Carotid ultrasound, School-age nutritional education program
- Where
- 2 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Stroke, National Institutes of Health Stroke Scale
Multivariate Analysis of Serum High Sensitivity C-Reactive Protein in Patients With Acute Phase Stroke
Stroke is one of main causes of death and impairment worldwide. Objective of this study is to analyze serum High Sensitivity C-Reactive Protein in acute phase stroke in patients attended at Petróleos Mexicanos Hospital Central…
- Conditions
- Stroke, National Institutes of Health Stroke Scale, Serum High Sensitivity C-Reactive Protein
- Trial name
- MAASP (NCT02171858)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital Central Sur de Alta Especialidad
Stroke
Effects of HIIT on Muscle Strength, Atrophy and Aerobic Capacity in Stroke Patients.
To determine the effects of High-Intensity Interval Training on muscle strength, atrophy, and aerobic capacity in stroke patients.
- Trial name
- NCT06292442
- Testing
- traditional physical therapy, High intensity interval training
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stroke
Motor Excitability Study of High Definition Transcranial Direct Current Stimulation (HD-tDCS) in Chronic Stroke
High definition tDCS will be conducted to both stroke and healthy subjects on primary motor cortex area to explore the motor excitability changes before and after stimulation.
- Trial name
- NCT02960009
- Testing
- HD-tDCS
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Atherosclerotic Cardiovascular Disease, Cardiovascular Diseases
Immunomodulatory Effects of PCSK9 Inhibition
Cardiovascular disease (CVD) represents the leading cause of death worldwide. While medications, such as statins, significantly reduce atherosclerotic CVD (ASCVD) risk by lowering low density lipoprotein levels, they may also…
- Conditions
- Atherosclerotic Cardiovascular Disease, Cardiovascular Diseases, Atherosclerosis, Arterial Inflammation
- Trial name
- INSPIRAR (NCT05720156)
- Testing
- 99mTc-tilmanocept SPECT/CT scanning
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stroke, Cerebellum
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes.
- Trial name
- NCT06458153
- Testing
- Neural responses to speech functional localizer, Neural responses to silent articulation, Neural responses to self vs. externally generated speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cognitive Impairment, Stroke
Effect of a fNIRS-based Personalized Multi-domain Intervention on Cognitive in Elderly Population With High Risk of Stroke
This functional near-infrared spectroscopy-based personalized multidomain intervention study aims to prevent cognitive impairment and reduce dementia and cerebrovascular events in 45-74 years old persons with high risk of stroke…
- Conditions
- Cognitive Impairment, Stroke, Dementia
- Trial name
- NCT05930249
- Testing
- Personalized multidomain intervention
- Where
- China
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebrovascular Accident, Stroke
Screening and Management of High-risk Populations of Stroke in Dehui City
This epidemiological survey is to analyze the prevalence rate of stroke and exposure rate of risk factors in sampling population aged 40 years and over (born before December 31,1975) in Dehui City, to provide scientific basis for…
- Conditions
- Cerebrovascular Accident, Stroke, Hypertension, Diabetes Mellitus
- Trial name
- SAMHPSDC (NCT05039034)
- Testing
- Advice according to primary prevention guidelines on stroke of China
- Where
- China
- Volunteers
- 4,100 people, healthy volunteers welcome
- Sponsor
- Yi Yang
Stroke, Fall
Predicting Fall Risk in Stroke Patients Using a Machine Learning Model and Multi-Sensor Data
The study assesses a machine learning model developed to predict fall risk among stroke patients using multi-sensor signals. This prospective, multicenter, open-label, sponsor-initiated confirmatory trial aims to validate the…
- Trial name
- NCT06380049
- Testing
- EMG Analysis Software
- Where
- South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Aphasia
The Usage of High-resolution Magnetic Resonance Imaging in Patients With Post-stroke Aphasia for Predicting the Outcome
Combined analysis of functional and structural language network changes may be a good model for predicting language outcome.
- Trial name
- NCT03475745
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Ischemic Stroke, Transient Ischemic Attack
Ticagrelor Based De-Escalation of Dual Antiplatelet Therapy in Ischemic Stroke
This is a randomized, controlled, outcome assessor blind, parallel group design pilot study on 100 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The aim of study is to compare the efficacy…
- Trial name
- DEDAPT-TICA (NCT06653348)
- Testing
- Ticagrelor 60 + Aspirin, Ticagrelor 90 + aspirin
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Stroke
Real-time Neuromuscular Control of Exoskeletons
The purpose of this study is to develop a real-time controller for exoskeletons using neural information embedded in human musculature.
- Trial name
- NCT04661891
- Testing
- Isometric contractions, Isokinetic contractions, Dynamic contractions
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Parkinson Disease
Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk
The purpose of this study is to evaluate the feasibility and efficacy of a smart airbag system that detects and mitigates fall-related impact in individuals with high fall risk.
- Conditions
- Stroke, Parkinson Disease, Lower Limb Amputation Knee, Fall Injury
- Trial name
- NCT05076565
- Testing
- Airbag Belt Fall Protection System
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Atherosclerosis, Stroke
Evaluation of Vascular Structure in Elderly Using High-frequency Ultrasound and Construction of a Multimodal Risk Assessment System for Cardiovascular Diseases: a Multicenter Study
Coronary heart disease(CHD), stroke, and hypertension are major diseases that seriously affect human health.Pathologic changes in the arteries involved in the above diseases mainly occur in the intimal or medial layer of the…
- Conditions
- Atherosclerosis, Stroke, Coronary Disease
- Trial name
- NCT06221618
- Testing
- High-frequency carotid arteries ultrasound, CCTA, Cranial MRA
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Stroke
Effects of Power and High-Intensity Gait Training for Functional Mobility an Ambulation in Chronic Stroke
This randomized controlled trial aims to determine the combined effect of power training and high-intensity gait training on functional mobility and locomotion following chronic stroke.
- Trial name
- NCT07249658
- Testing
- power training + high-intensity gait training, power training, high-intensity gait training
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riphah International University