Clinical trials: High Astigmatism
Astigmatism, High Myopia
Comparison Between TICL and ICL+AK for High Myopic Astigmatism
To compare the outcomes of a toric Implantable Collamer Lens (ICL) and a spherical Implantable Collamer Lens combined with astigmatic keratotomy (AK) in the correction of high myopic astigmatism.
- Trial name
- NCT03202485
- Testing
- Toric Implantable Collamer Lens, ICL + Astigmatic keratotomy
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Astigmatism High Both, Pseudophakia
Toric Trifocal IOL Treatment With High Astigmatism and Hyperopia vs SMILE Enhancement After Trifocal IOL Treatment
The aim of this study is to assess visual and refractive outcomes after Toric Trifocal lens implantation and visual outcomes after laser vision correction (LVC) - ReLex Smile to correct residual refraction after 6 months of Toric…
- Conditions
- Astigmatism High Both, Pseudophakia, Hyperopia
- Trial name
- NCT04468022
- Testing
- Toric Trifocal IOL
- Where
- Kosovo
- Volunteers
- 40 people
- Sponsor
- Eye Hospital Pristina Kosovo
Astigmatism
Limbal Astigmatic Keratotomy to Correct High Degrees of Astigmatism After Phacoemulsification
Compare manually performed Astigmatic Keratotomy to femtosecond laser astigmatic keratotomy to manage corneal astigmatism more than three diopters after phacoemulsification.
- Trial name
- NCT06179355
- Testing
- manual astigmatic keratotomy, femtosecond laser astigmatic keratotomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Astigmatism, Hyperopia
ICL and LASIK for Hyperopic Astigmatism
This study investigates a two-step treatment for people with severe farsightedness combined with astigmatism. The first step involves implanting a specially designed lens inside the eye (a spherical Implantable Collamer Lens, or…
- Trial name
- NCT06742541
- Testing
- Implantable Collamer Lens (ICL) followed by a planned adjunctive LASIK postoperatively
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- McGill University
Keratoconus, High Myopia
Anterior Segment and Corneal Parameters in Keratoconus and High Myopic Astigmatism Using Schiempflug Imaging
The purpose of this study was to compare Scheimpflug corneal tomography findings in keratoconus and high myopic astigmatic eyes, as well as to establish the parameters distinguishing keratoconus from high myopic astigmatism.
- Trial name
- NCT06739018
- Testing
- pentacam scheimpflug tomography
- Where
- 2 sites in Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
Myopia
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Moderate to High Myopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of moderate to high myopia (nearsightedness), when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762541
- Testing
- MEL 80 Treatment of High Myopia
- Where
- 5 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Keratoconus, Astigmatism High
Enhancing Scleral Lens Fit With Advanced Imaging
The goal of this experimental clinical trial is to enhance the predictability and precision of scleral lens fitting in patients with complex corneal conditions such as keratoconus, post-surgical irregularities, and severe dry eye…
- Trial name
- SPLEPICA (NCT06751615)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fernando Fernandez Velazquez
Myopia, Hyperopia
Clinical Investigation of the Vision-R800 Device.
Randomized, bilateral, cross-over dispensing study of a standard and VR800 refraction and associated spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism, Presbyopia
- Trial name
- NCT04208750
- Testing
- Vision R-800 Phoropter, Standard Phoropter
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Pete Kollbaum, OD, PhD
Astigmatism
Comparison of Cross-cylinder and Conventional Photorefractive Keratectomy(PRK) in Correcting Medium-high Astigmatism
The purpose of this study is to determine whether cross-cylinder approach is more effective than routine method in laser correction of astigmatism.
- Trial name
- PRK (NCT00663923)
- Testing
- photorefractive keratectomy (PRK)
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tabriz University
Myopia, Myopic Astigmatism
Laser In-situ Keratomileusis With Crosslinking Compared to Conventional LASIK in Patients With High Myopia
The objectives of this study are to evaluate the safety and efficacy of a treatment regimen for high myopia and myopic astigmatism: LASIK followed by crosslinking performed with the KXL Crosslinking-System and VibeX Xtra…
- Conditions
- Myopia, Myopic Astigmatism, Crosslinking, Corneal Ectasia
- Trial name
- NCT03913338
- Testing
- LasikXtra, LASIK
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Clinic Frankfurt
Hyperopia, High Astigmatism
Fresh Corneal Lenticule Implantation in Hyperopic Patients With High Astigmatism
The refractive combination of high hyperopia with high astigmatism is difficult to treat surgically. In addition, there are not many suitable options to offer such patients presenting with this condition.
- Trial name
- NCT04616144
- Testing
- Fresh Corneal Lenticule Implantation using Relex-Smile VisuMax Femtosecond Laser
- Where
- Kosovo
- Volunteers
- 55 people
- Sponsor
- Eye Hospital Pristina Kosovo
Myopia, Hyperopia
High Refractive Index Material 510(k)
The purpose of this study is to establish the substantial equivalence of the HDS HI 1.54™ to the paflufocon C material control lenses to correct myopia and hyperopia with and without astigmatism.
- Trial name
- PVS-07-07 (NCT00766168)
- Testing
- HDS HI 1.54; pahrifocon A, FluoroPerm 30 RGP; paflufocon C
- Where
- 8 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Astigmatism, Phacoemulsification
Effectiveness and Safety of Limbal Relaxing Incisions for Correcting Post Phacoemulsification High Astigmatism
To compare the effect of Limbal relaxing incisions (LRIs) plus spectacle correction versus spectacle correction alone on subjective and objective improvement in visual function for correcting post phacoemulsification high…
- Trial name
- NCT06896357
- Testing
- Limbal relaxing incisions
- Volunteers
- 30 people
- Sponsor
- Assiut University
Dry Eye
SAS 1: Develop Ocular Disease (OSD) Diagnostic, Algorithms, and Management Protocols for Cataract Surgery
Patient: Tear film issues resulting in poor visual outcomes are a major cause of dissatisfaction after cataract surgery. There is no universal best preoperative algorithm for managing the ocular surface prior to surgery.
- Trial name
- NCT07323264
- Where
- Singapore
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louis Tong
Cataract, Astigmatism
Evaluation of Toric Intraocular Lens(IOL) Combined With Capsular Tension Ring(CTR) in Patients With Cataract Combined With High Myopia
The objective of this study is to evaluate the postoperative visual quality and IOL stability in patients with cataracts and high myopia who have undergone surgery using astigmatism-correcting IOLs in conjunction with tension…
- Conditions
- Cataract, Astigmatism, Intraocular Lens Rotation
- Trial name
- NCT06571773
- Testing
- intraoperative implantation of Capsular Tension Ring, none intraoperative implantation of CTR
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Shanghai 10th People's Hospital
Cataracts, Astigmatism
Post Approval Study of the AcrySof® IQ Toric Intraocular Lens (IOL) Models SN6AT6-SN6AT9
The purpose of this study is to evaluate the use of toric high cylinder power intraocular lenses in a larger population in clinical practice and assure the continued safety of these approved devices.
- Trial name
- NCT01601665
- Testing
- SN6AT6 Intraocular Lens, SN6AT7 Intraocular Lens, SN6AT8 Intraocular Lens
- Where
- United States
- Volunteers
- 477 people
- Sponsor
- Alcon Research
Nearsightedness, Astigmatism
High Resolution Wavefront-guided vs. Wavefront Optimized LASIK
The investigators are comparing outcomes of LASIK surgery using a high definition wavefront-guided laser to a wavefront-optimized laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT02565537
- Testing
- LASIK
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Keratoconus, Ectasia
Higher Irradiance in Keratoconus Ectasia
The purpose of the study is to see if brighter lights will allow for shortening of the treatment time required to stabilize the eyes of patients with keratoconus or a bulging cornea.
- Trial name
- NCT01789333
- Testing
- UVA Light with irradiance exposure of 9 mW/cm2, Riboflavin 0.1% ophthalmic solution
- Where
- United States
- Sponsor
- Stephen Trokel
Cataract Senile, Myopia, High-Grade
Evaluation of Axial Stability of Two Models of Intraocular Lenses in Patients With an Eye Length More Than 26 mm
Some parameters, such as a change in the optic tilt and axial decentration, can affect the optical characteristics of intraocular lenses (IOLs) in postoperative period, which leads to residual refractive errors and other…
- Conditions
- Cataract Senile, Myopia, High-Grade, Corneal Astigmatism
- Trial name
- NCT05129566
- Testing
- IOL Clareon AutonoMe, IOL Hoya iSert 251
- Where
- Russia
- Volunteers
- 78 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Anisometropia, Hyperopia
Photorefractive Keratectomy for Severe Anisometropia and Isoametropia Associated With Amblyopia
Photorefractive keratectomy (PRK) with excimer laser has been used successfully to treat myopia, hyperopia, and astigmatism in adults for over 35 years.
- Conditions
- Anisometropia, Hyperopia, High Myopia, Amblyopia Isometropic
- Trial name
- NCT03610997
- Testing
- Photorefractive keratectomy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Baylor College of Medicine