Clinical trials: Heterotaxy Syndrome
Heterotaxy Syndrome, Congenital Heart Defects
Molecular Genetics of Heterotaxy and Related Congenital Heart Defects
The goal of this study is to obtain specimens and data from individuals and their families with heterotaxy and related congenital heart defects in order to clarify the molecular genetics of this disorder.
- Trial name
- NCT02432079
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Indiana University
Thyroid Carcinoma
Enhancing Radioiodine (RAI) Incorporation Into BRAF Mutant, RAI-Refractory Thyroid Cancers With the BRAF Inhibitor Vemurafenib: A Pilot Study
The purpose of this study is to find out what effects, good and/or bad, a drug called vemurafenib, either alone or combined with another treatment called radioactive iodine, has on the patient and thyroid cancer.
- Trial name
- NCT02145143
- Testing
- Vemurafenib, serial 124I PET/CT, thyrotropin alpha
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Heterotaxy Syndrome
Heterotaxy Syndrome and Intestinal Rotation Abnormalities - A Prospective Study
Infants with heterotaxy syndrome (HS) are born with an abnormal arrangement of organs along the right-left body axis. Abnormalities of intestinal rotation and fixation are commonly associated with HS.
- Trial name
- NCT01591928
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Heterotaxy Syndrome
Defining Immunodeficiency in Heterotaxy Syndrome: Pilot Study Data
The investigators aim with this study is to investigate the mechanisms of immune deficiency in patients with heterotaxy syndrome through the use of novel biomarkers and a prospective questionnaire survey documenting the burden of…
- Trial name
- NCT01929967
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Congenital Disorders
Racial Distribution of Heterotaxy Syndrome
Heterotaxy syndrome is a heterogeneous disease that is the result of a failure of normal right-left lateralization of the abdominal and thoracic organs during development.
- Trial name
- NCT00485654
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Children's Healthcare of Atlanta