Clinical trials: Hernia
Ventral Hernia
Hernia Repair in Multiply Morbid Patients
Support of a ventral hernia repair with a prosthetic mesh has been demonstrated to result in a diminished rate of hernia recurrence.
- Trial name
- RAM2P (NCT00930787)
- Testing
- Strattice Reconstructive Tissue Matrix (Hernia Repair), Proceed Surgical Mesh (Hernia repair)
- Where
- 13 sites in United States
- Volunteers
- 23 people
- Sponsor
- LifeCell
Incisional Hernia of Anterior Abdominal Wall
Phasix Mesh Underlay During Loop Ileostomy Closure
This prospective study will evaluate whether placement of long-acting absorbable Phasix mesh during loop ileostomy closure reduces the development of an incisional hernia at the ileostomy closure site in patients with a BMI…
- Trial name
- NCT07871630
- Testing
- Long-acting absorbable mesh
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Corewell Health West
Chronic Post-surgical Pain
Duloxetine to Prevent Chronic Postsurgical Pain After Inguinal Hernia Repair in Patients at High Risk
The clinical trial will be conducted in 14 Spanish hospitals. It is estimated, based on our previous studies, that 2855 patients scheduled for elective inguinal hernia surgery will have to be assessed to detect patients with ≥…
- Trial name
- GENDOLCAT3 (NCT06606067)
- Testing
- Duloxetine
- Where
- Spain
- Volunteers
- 294 people
- Sponsor
- Parc de Salut Mar
Chronic Pain Following Surgical Procedure for Cancer
A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair
Patients were randomized into two groups: Group Gabapentine ( G group) received 600 mg of Gabapentin (two tablets) two hours prior to surgery and saline solution before induction of spinal anesthesia and group Ketamine ( K group)…
- Trial name
- NCT04700592
- Testing
- Gabapentin versus Ketamine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Hiatal Hernia
SurgiMend Mesh at the Hiatus
Prospective, single-arm, open-label study to evaluate re-occurrence and quality of life in subjects undergoing primary Hiatal hernia repair using SurgiMend biological mesh.
- Trial name
- NCT04282720
- Testing
- SurgiMend Mesh
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Kettering Health Network
Inguinal Hernia, Constipation
Relationship Between Constipation and Inguinal Hernia
The purpose of this study is to asses the effect of chronic constipation on formation of inguinal hernia using Constipation Severity Scale.
- Trial name
- NCT02749682
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Siverek Devlet Hastanesi
Incisional Hernia
ProGripTM Self-Gripping Polyester Mesh in Incisional Hernia Prevention
Interventional, prospective, multicenter, post-marketing clinical follow-up study. After midline laparotomy, the probability to develop an incisional hernia ranges from 10% to 50% depending on the complexity of the surgery and…
- Trial name
- POETRY (NCT03912662)
- Testing
- Mesh augmented reinforcement
- Where
- 11 sites in France
- Volunteers
- 32 people
- Sponsor
- Medtronic - MITG
Hernia, Diaphragmatic, Hypertension, Pulmonary
Chronic Sildenafil for Severe Diaphragmatic Hernia
The purpose of this study is to test if sildenafil is effective in the treatment of infants with severe congenital diaphragmatic hernia (determined by the presence of prolonged pulmonary hypertension or prolonged oxygen…
- Conditions
- Hernia, Diaphragmatic, Hypertension, Pulmonary, Hypoplasia, Pulmonary
- Trial name
- NCT00133679
- Testing
- sildenafil
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of California, San Francisco
Ventral Hernia
Tacks Versus Glue for Mesh Fixation in Laparoscopic Ventral Hernia Repair Treating Defects Between 2 and 5 cm Width
In laparoscopic ventral hernia repair, an abundance of methods has been developed to fix the mesh to the abdominal wall, including sutures (non-absorbable or absorbable), staples (non-absorbable or absorbable), clips, tacks…
- Trial name
- NCT03429374
- Testing
- Liquiband Fix8, Absorbable tack
- Where
- 11 sites in Belgium
- Volunteers
- 16 people
- Sponsor
- Duomed
Inguinal Hernia
Flemish Inguinal and Femoral Hernia Prospective Registry
Prospective registry. The purpose of this clinical trial will be to measure surgical outcome parameters (e.g. recurrence, chronic pain and other quality indicators) after inguinal hernia repair using Patient Reported Outcome…
- Trial name
- FLIPR (NCT04623580)
- Testing
- Surgical inguinal or femoral hernia repair
- Where
- 2 sites in Belgium
- Volunteers
- 560 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Inguinal Hernia
Open and Laparoscopic Hernia Repair. A Comparative Study
A retrospective comparative study in a pediatric surgery center to compare the outcomes of 2 approaches of hernia repair in the pediatric population.
- Trial name
- NCT05011786
- Testing
- hernia repair/ligation of the hernial sac
- Where
- Jordan
- Volunteers
- 155 people
- Sponsor
- Ibrahim Khrais
Incisional Hernia, Malignancy
Risk Factors for Development of Incisional Hernia in Transverse Incisions
RESEARCH PROJECT OBJECTIVES The aim of this planned study is to evaluate factors, with particular reference to surgical technique of abdominal closure, accumulation of advanced glycation end products, and collagen content in the…
- Trial name
- NCT03561727
- Testing
- Mass closure technique, Layered closure technique
- Where
- Poland
- Volunteers
- 392 people
- Sponsor
- Medical University of Warsaw
Ventral Hernia
Regional Differences In Indication for Ventral Hernia Repair
The aim of the present study is to investigate whether there are differences in indication for ventral hernia repair and surgical approach among hernia surgeons from different geographical regions of Denmark.
- Trial name
- NCT02263625
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Hernia, Abdominal, Recurrence
Nationwide Long-term Outcome Surveillance of Physiomesh® vs. Other Meshes in Laparoscopic Incisional Hernia Repair
The primary aim of the present study was to show how a national clinical register combined with other nationwide administrative registers may serve as a tool for pre- and post-marketing evaluation of new mesh and mesh fixation…
- Conditions
- Hernia, Abdominal, Recurrence, Postoperative Complications
- Trial name
- NCT03846661
- Testing
- Physiomesh
- Where
- Denmark
- Volunteers
- 3,338 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Incidence of Surgical Site Infection, Morality
Changing the Surgical Team for Wound Closure and Surgical Site Infection
Surgical site infection is a frequent complication after abdominal surgery. The wound closure is done at the end of the procedure when the attention of the entire team may be affected because of tiredness and reduced attention of…
- Conditions
- Incidence of Surgical Site Infection, Morality, Fascial Hernia
- Trial name
- NCT04503642
- Testing
- Changing the surgical team for wound closure
- Where
- Switzerland
- Volunteers
- 1,160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Nursing Care, Spine Surgery
Dependence, Frailty, and Kinesiophobia on Early Postoperative Mobilization and Self-Care Ability in Patients Undergoing Lumbar Disc Herniation Surgery
Lumbar disc herniation is a common condition that may impair physical functioning and reduce independence in activities of daily living.
- Conditions
- Nursing Care, Spine Surgery, Perioperative Care
- Trial name
- NCT07762183
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Aydin Adnan Menderes University
Spinal Anaesthesia, Herniorrhaphy
Assessment of the Impact of Two Dexmedetomidine Dosages Added with Bupivacaine in Ultrasound-Guided Transversus Abdominis Plane Block for Postoperative Analgesia Following Inguinal Hernia Repair
The principal outcome assessed was the duration until the initial request for analgesia post-surgery. The secondary outcomes encompassed the total quantity of analgesics administered (ketorolac, paracetamol, and morphine) within…
- Conditions
- Spinal Anaesthesia, Herniorrhaphy, Transversus Abdominis Plane Block
- Trial name
- NCT06703229
- Testing
- The Transversus Abdominis Plane (TAP) block, The transverse abdominis plane (TAP) block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Congenital Diaphragmatic Hernia
CDH - Optimisation of Neonatal Ventilation
To determine the appropriate volume (size) of ventilator breath during volume-targetted ventilation for infants born with congenital diaphragmatic hernia.
- Trial name
- CDH-ONV (NCT02849054)
- Testing
- Measurement of PTPdi, TTV at 4ml/kg, TTV at 5ml/kg
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- King's College London
Recto-intercostal Fascial Plane Block, Epigastric Hernia
Bilateral Recto-Intercostal Fascial Plane Block in Epigastric Hernia Repair
The aim of this study is to evaluate the efficacy and safety bilateral recto-intercostal fascial plane block (RIFPB) in epigastric hernia.
- Conditions
- Recto-intercostal Fascial Plane Block, Epigastric Hernia, Analgesia
- Trial name
- NCT06092073
- Testing
- recto-intercostal fascial plane block, bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
HERNIA, VENTRAL
ProLOVE - Prospective Randomized Study of Midline Incisional Hernia Treatment
This purpose of this study is to compare the recovery after an operation of an incisional hernia within the limits of the rectus muscles of the abdominal wall.
- Trial name
- ProLOVE (NCT00472537)
- Testing
- Retromuscular Mesh repair of midline incisional hernia, Laparoscopic repair of midline incisional hernia
- Where
- 7 sites in Sweden
- Volunteers
- 157 people
- Sponsor
- Skane University Hospital