Clinical trials: Hemorrhoid Bleeding
Hemorrhoids, Hemorrhoid Pain
Preoperative Micronized Flavonoid Fraction (MFF) Use in Multimodal Anesthesia in Anorectal Surgery
Aim: To assess the efficiency of the micro-flavonoid fraction (MMF) administration prior to anorectal surgery with spinal anesthesia on postoperative pain severity reduction.
- Conditions
- Hemorrhoids, Hemorrhoid Pain, Hemorrhoidal Bleeding
- Trial name
- NCT05772351
- Testing
- micronized flavonoid fraction
- Where
- Russia
- Volunteers
- 182 people
- Sponsor
- Center of Endourology "Endocenter"
Hemorrhoid, Hemorrhoid Bleeding
Trial of Latex vs Non-latex Hemorrhoid Banding
This study will involve the recruitment of adult patients with hemorrhoids for whom rubber band ligation is the recommended treatment. Patients will be randomized to receive banding with a latex band or non-latex band.
- Trial name
- NO-Tex (NCT06625138)
- Testing
- Latex Band, Non-Latex Band
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Huntington Memorial Hospital
Hemorrhoids, Bleeding Disorder
Sclerotherapy With Polidocanol Foam In The Treatment Of Hemorrhoidal Disease In Patients With Bleeding Disorders
Treatment of hemorrhoidal disease includes a conservative approach (dietary and behavioral measures, venotropic and topical medication), office-based treatments and surgery.
- Trial name
- NCT04188171
- Testing
- Polidocanol foam sclerotherapy
- Where
- 3 sites in Portugal
- Volunteers
- 150 people
- Sponsor
- Universidade do Porto
Grade III and IV Hemorrhoids
Haemorrhoidectomy With vs Without Lateral Internal Sphincterotomy
Hemorrhoids are a common anorectal condition that often require surgical treatment in advanced stages. Open hemorrhoidectomy is effective but is frequently associated with significant postoperative pain and early bleeding.
- Trial name
- NCT07360912
- Testing
- Hemorrhoidectomy With LIS, Conventional Hemorrhoidectomy
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Baghdad
Hemorrhoids, Internal
The Effect of Rubber Band Ligation in Bleeding Internal Hemorrhoids.
In this study, the researchers planned to compare the treatment results of patients undergoing rubber band ligation in addition to drug therapy in hemorrhagic internal hemorrhoids patients and those treated only with…
- Trial name
- NCT04290351
- Testing
- band ligation, oral 450 mg diosmin+50 mg hesperidin
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Bleeding, Stricture
Comparison of the Short-term Outcomes of Using DST and PPH Staplers in the Treatment of Grade III and IV Hemorrhoids
The hemorrhoidal disease affects approximately 4.4%-36% of the general population, and it has been estimated that >50% of the population aged >50 years experiences hemorrhoidal problems .
- Trial name
- NCT04058223
- Testing
- Hemorrhoidopexy
- Where
- Taiwan
- Volunteers
- 2 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Hemorrhoid, Internal Hemorrhoids
Prospective HemorrhoIdaL EmboliSation (PILES) Registry
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults…
- Conditions
- Hemorrhoid, Internal Hemorrhoids, Hemorrhoid Bleeding, Hemorrhoidal Bleeding
- Trial name
- PILES (NCT07635784)
- Testing
- Hemorrhoid Artery Embolization
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Joint & Vascular Institute
Haemorrhoidal Bleeding
ARTerial EMbolization for haemorrhoIdal Disease (ART.EM.I. Study)
Haemorrhoidal disease is amongst the most common rectal conditions causing significant distress to the affected patients. Current surgical techniques for the treatment of internal haemorrhoids are associated with several…
- Trial name
- ARTEMIS (NCT04684251)
- Testing
- Coil embolisation of hemorrhoidal arteries.
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Hemorrhoids Internal, Hemorrhoids Second Degree
Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal Hemorrhoids
This Phase II study will compare rectal artery embolization with operative hemorrhoidectomy in adults with symptomatic bleeding grade 2 and 3 internal hemorrhoids.
- Conditions
- Hemorrhoids Internal, Hemorrhoids Second Degree, Hemorrhoids Third Degree
- Trial name
- HemEmbo (NCT07844629)
- Testing
- Rectal Artery Embolization, Operative Hemorrhoidectomy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Colorado, Denver
Piles, Bleeding
Is Doppler Necessary in Haemorrhoidal Artery Ligation Operation?
Haemorrhoidal artery ligation operation (HALO) is an operation that ties off vessels to piles. This study examines whether the ultrasound (doppler) is necessary to guide this tying off or not.
- Trial name
- NCT01051180
- Testing
- HALO
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Poole Hospital NHS Foundation Trust
Bleeding Hemorrhoids, Rectal Evacuation Disorders
Rectal Evacuation Disorders and Straining-associated Symptoms in Bleeding Hemorrhoids
This study aims to understand the mechanisms of straining on anorectal testing, to better help people receive more effective treatment advice.
- Trial name
- NCT07161765
- Testing
- Anorectal manometry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Hemorrhoid, Hemorrhoid Bleeding
Bleeding Reduction in Grade II-III Haemorrhoids Through Embolization Treatment
BRIGHT is a Europe-wide study that will follow up to 250 adults with bleeding symptoms from haemmorhoids (Grade II-III categories).
- Trial name
- BRIGHT (NCT07264413)
- Testing
- Haemorrhoid artery embolizsation (HAE)
- Volunteers
- 250 people
- Sponsor
- Cardiovascular and Interventional Radiological Society of Europe
Hemorrhoids
Comparison Between Two Endoscopic Treatments of Bleeding Internal Hemorrhoids:Band Ligation and Electrocoagulation Probe
The purpose of this study is to determine which treatment, band ligation (placing rubber bands around the hemorrhoids) or BICAP electrocoagulation (using electricity to cauterize) is safer and more effective endoscopic treatment…
- Trial name
- NCT00630669
- Testing
- Rubber band ligation, Bipolar coagulation
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, Los Angeles
Haemorrhoid, Haemorrhoidal Bleeding
Hemorrhoid Suture Mucopexy Combined With Laser Hemorrhoidoplasty
This prospective cohort study evaluates whether combining "suture mucopexy" (a simple stitch-based lift of prolapsed tissue) with Laser Hemorrhoidoplasty (LHP) can effectively relieve pain, bleeding and prolapse in adults with…
- Conditions
- Haemorrhoid, Haemorrhoidal Bleeding, Anorectal Surgeries, Anorectal Diseases
- Trial name
- HeMuLa (NCT07404774)
- Testing
- Laser Haemorrhoidoplasty and Suture Mucopexy
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Grade II Internal Hemorrhoids With Bleeding
A Phase III Clinical Trial Evaluating the Efficacy and Safety of TriThien Duoc Capsules in Grade II Internal Haemorrhoids Patients With Bleeding Compared to Diosmin.
A Phase III, randomized, double-blind, placebo-controlled clinical trial has been conducted to evaluate the efficacy and safety of Trĩ Thiên Dược capsules in people with grade II internal hemorrhoids with bleeding.
- Trial name
- NCT07369635
- Testing
- Intervention Group: Tri Thien Duoc Capsules, Control group (diosmin)
- Where
- Vietnam
- Volunteers
- 172 people
- Sponsor
- Hanoi Medical University
Anorectal Disorder
The Efficacy of Aescin in Combination With MPFF in the Early Control of Bleeding From Acute Internal Hemorrhoids, A Randomized Controlled Trial
Hemorrhoidal disease, characterized by symptomatic enlargement and distal displacement of anal cushions, has been a subject of recognition and management for centuries.
- Trial name
- NCT06363513
- Testing
- Aescin in Horse Chestnut, Flavonoid
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Chiang Mai University
Liver Cirrhosis, Internal Hemorrhoid
A Comparison of Flexible Endoscopic Polidocanol Liquid and Foam Sclerotherapy in Cirrhotic Patients With Bleeding From Internal Hemorrhoids
Haemorrhoids are the most common proctologic disease, affecting up to 36% of people in the developed world. Sclerotherapy is defined as the injection of sclerosing agents at the apex of the internal hemorrhoidal complex, above the…
- Trial name
- NCT06031740
- Testing
- Sclerotherapy with 1.5% polidocanol, Foam sclerotherapy.
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Hemorrhoids
Bleeding in Laser Haemorrhoidoplasty
Treatment options for haemorrhoid can be classified mainly into lifestyle modification, medical and procedural. Laser haemorrhoidoplasty (LHP) is a minimally invasive procedure which is effective in treating grade 2-4…
- Trial name
- NCT04667169
- Testing
- Haemorrhoidal Artery Ligation, Laser Haemorrhoidoplasty
- Where
- Malaysia
- Volunteers
- 76 people
- Sponsor
- University of Malaya
Arteriovenous Malformation, Gastrointestinal Bleed
Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils
The purpose of the Case-Specific Health Care Professional (HCP) Clinical Survey for Concerto Versa™ Detachable Coils, also known as the Concerto Versa HCP Clinical Assessment, is to collect early clinical data from HCPs to assess…
- Conditions
- Arteriovenous Malformation, Gastrointestinal Bleed, Gastric Varices, Hemorrhoid
- Trial name
- NCT07639853
- Testing
- Concerto Versa™ Detachable Coils
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Medtronic Endovascular
Hemorrhoid Bleeding
Validation of Hemorrhoidal Bleeding Score
The principal manifestation of hemorrhoidal disease is bleeding; however the severity evaluation is today based on prolapsus (Goligher classification) and bleeding factor is not included.
- Trial name
- NCT03060616
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Fondation Hôpital Saint-Joseph