Clinical trials: Hemorrhagic Stroke, Intracerebral
Sars-CoV2, Severe Neurologic Injury
COVID-19 Brain Injury
A prospective cohort minimal risk study to determine the impact of the COVID-19 crisis on outcomes of neurologically injured ICU patients.
- Conditions
- Sars-CoV2, Severe Neurologic Injury, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- NCT04496076
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Intracerebral Hemorrhage
Multinational Survey of Epidemiology, Morbidity, and Outcomes in Intracerebral Hemorrhage
The aim of this project is development of a comprehensive, prospective, multinational, multicenter, hospital-based, data repository for patients with intracerebral hemorrhage.
- Trial name
- MNEMONICH (NCT02567162)
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Nervous System Diseases, Cerebrovascular Disorders
Efficacy and Safety of Antihypertensive Treatment With Mobile Stroke Units in Ultra-Early Intracerebral Hemorrhage
MSU-ICH is a prospective, multicenter, Week-wise-randomized, open-label, blinded-endpoint (PROBE) clinical trial comparing ultra-early prehospital blood pressure lowering delivered by a Mobile Stroke Unit (MSU) with standard…
- Conditions
- Nervous System Diseases, Cerebrovascular Disorders, Cardiovascular Diseases, Vascular Diseases
- Trial name
- MSU-ICH (NCT07665827)
- Testing
- Mobile Stroke Unit Management, Standard Management
- Where
- China
- Volunteers
- 706 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke
Long Term Outcome After Hemorrhagic Stroke Surgery
The investigators retrospectively reviewed all patients with neurosurgical operations for hemorrhagic stroke (intracerebral hemorrhage) between 1999 and 2008.
- Trial name
- NCT01409252
- Where
- China
- Volunteers
- 191 people
- Sponsor
- Chinese University of Hong Kong
Stroke, CVA (Cerebrovascular Accident)
MORbidity PRevalence Estimate In StrokE
Information regarding the likely progress of post-stroke symptoms is vitally important to stroke survivors to allow them to plan for the future and to adjust to life after stroke.
- Conditions
- Stroke, CVA (Cerebrovascular Accident), CVA; Sequelae, Stroke, Ischemic
- Trial name
- MORe PREcISE (NCT03605381)
- Where
- 3 sites in United Kingdom
- Volunteers
- 500 people
- Sponsor
- Aneurin Bevan University Health Board
Intraventricular Hemorrhage, Intracerebral Hemorrhage
The Natural History of Procalcitonin in Hemorrhagic Stroke
Approximately 12% of strokes in the United States are hemorrhagic.1 Hemorrhagic stroke can lead to multiple complications including fever that is not infectious.
- Trial name
- NCT01498705
- Testing
- Procalcitonin level
- Where
- United States
- Sponsor
- CAMC Health System
Intracerebral Hemorrhage, Nontraumatic Intracerebral Hemorrhage
Detection of an Endovascular Treatment Target in Patients With an Acute, Spontaneous Intracerebral Hemorrhage
This study is to determine if a treatment target for a potential endovascular therapy exists in patients with an acute, spontaneous (non-traumatic) ICH.
- Trial name
- HemEXPLO (NCT05504941)
- Testing
- Diagnostic, cerebral Digital Subtraction Angiography (DSA)
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University Hospital, Basel, Switzerland
Intracerebral Hemorrhage, Cerebral Edema
Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage
The purpose of this study is to test the safety and effectiveness of a single dose of fingolimod in patients with primary spontaneous intracerebral hemorrhage (ICH).
- Conditions
- Intracerebral Hemorrhage, Cerebral Edema, Stroke Hemorrhagic, Intracerebral Hemorrhage, Hypertensive
- Trial name
- FITCH (NCT04088630)
- Testing
- Fingolimod, Open-label Fingolimod
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University Health Sciences
Hemorrhagic Stroke, Intracerebral, Subarachnoid Haemorrhage (SAH)
AI-based Algorithm Development for Improved Diagnostics in the Intensive Care and Acute Stroke Setting Using Electroencephalography
The goal of this observational study is to develop and validate artificial intelligence (AI) algorithms that use subhairline EEG (a simplified EEG patch placed on the forehead and behind the ears) to predict neurological outcome…
- Conditions
- Hemorrhagic Stroke, Intracerebral, Subarachnoid Haemorrhage (SAH), Postanoxic Coma
- Trial name
- SMART-EEG (NCT07886957)
- Where
- Netherlands
- Volunteers
- 825 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Stroke Acute, Acute Ischemic Stroke AIS
One-Stop manaGemEnT For A Swift Initiation of Endovascular Therapy
Stroke, especially acute ischemic stroke (AIS) caused by a blocked blood vessel in the brain, is a leading cause of death and long-term disability.
- Conditions
- Stroke Acute, Acute Ischemic Stroke AIS, Hemorrhagic Stroke, Intracerebral
- Trial name
- GET-FAST (NCT07052045)
- Testing
- One Stop Management, Usual care management
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 390 people
- Sponsor
- Prof. Dr. Jan Liman
Ischemic Stroke, Atrial Fibrillation
Lixiana Acute Stroke Evaluation Registry
Study Design: Lixiana Acute Stroke Evaluation Registry (LASER) is a randomized controlled trial with an associated registry. Patients with previously known or newly diagnosed atrial fibrillation (AF) and acute ischemic stroke…
- Conditions
- Ischemic Stroke, Atrial Fibrillation, Hemorrhagic Transformation Stroke
- Trial name
- LASER (NCT03494530)
- Testing
- Edoxaban 60 MG, Edoxaban 30 mg
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Alberta
Wound Closure, Brain Tumor Adult
Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures
This research is studying a device already approved by the Food and Drug Administration (FDA) to treat wound closures. Researchers are studying a large group of people to continue to learn information about the safety of the…
- Conditions
- Wound Closure, Brain Tumor Adult, Spine, Neurovascular
- Trial name
- NCT07225101
- Testing
- STRATAFIX PDS and Monocryl suture
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Michigan
Stroke Hemorrhagic
Rapid Evacuation and Access of Cerebral Hemorrhage Trial
The main purpose of this study is to compare patients with a deep bleed in the brain undergoing surgery to patients receiving routine medical care.
- Trial name
- REACH (NCT06870812)
- Testing
- Surgical management, Medical Management
- Where
- 24 sites in United States
- Volunteers
- 600 people
- Sponsor
- Emory University
Intracerebral Hemorrhage, Intracranial Hemorrhages
Tenecteplase (TNK) in the Treatment of Intracerebral Hemorrhage (ICH)
The overall purpose of this study is to look at the safety and effectiveness of administering Tenecteplase (TNK) into the brain bleed (hematoma) instead of another clot-dissolving drug known as recombinant tissue plasminogen…
- Conditions
- Intracerebral Hemorrhage, Intracranial Hemorrhages, Hemorrhagic Strokes
- Trial name
- TNK in ICH (NCT06696131)
- Testing
- TNK
- Volunteers
- 5 people
- Sponsor
- Gaurav Gupta, MD
Stroke
Can Acupuncture Benefit Surgical Patients With Haemorrhagic Stroke?
The purpose is to establish whether acupuncture in addition to conventional rehabilitation programme can improve the functional outcome and quality of life of surgical patients with haemorrhagic stroke, as compared to…
- Trial name
- NCT01037894
- Testing
- Acupuncture, Conventional rehabilitation
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Chinese University of Hong Kong
Intracerebral Hemorrhage
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial
The objective of the rFVIIa for Acute Hemorrhagic Stroke Administered at Earliest Time (FASTEST) Trial is to establish the first treatment for acute spontaneous intracerebral hemorrhage (ICH) within a time window and subgroup of…
- Trial name
- FASTEST (NCT03496883)
- Testing
- Recombinant Activated Factor VII (rFVIIa)
- Where
- 88 sites in United States, Canada and 4 more
- Volunteers
- 860 people
- Sponsor
- Joseph Broderick, MD
Intracerebral Hemorrhage
A Pilot Study of Minocycline in Intracerebral Hemorrhage Patients
The MACH Trial is a pilot study of 400mg minocycline over five days in acute intracerebral hemorrhage patients. The study will evaluation the safety and efficacy of minocycline in intracerebral hemorrhage patients.
- Trial name
- MACH (NCT01805895)
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Augusta University