Clinical trials: Hemoptysis
Hemoptysis
Urokinase Like Plasminogen Activator Levels in Patients Undergoing Bronchoscopy
Some of the risk factors for bleeding following bronchoscopy is having a malignancy or an immunocompromised state. The etiology of this remains uncertain.
- Trial name
- NCT00929565
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Oklahoma
Bleeding, Hemoptysis
Prophylactic Tranexamic Acid Versus Adrenaline During Flexible Bronchoscopy
Endobronchial bleeding is a common complication of bronchoscopy. Major bleeding, although rare, can be life threatening and often requires advanced therapeutic interventional pulmonary procedures which are not widely available.
- Trial name
- TAVA2 (NCT06145191)
- Testing
- Tranexamic acid, Adrenaline
- Where
- Croatia
- Volunteers
- 1,013 people
- Sponsor
- Clinical Hospital Centre Zagreb
Tracheal Intubation, Postoperative Complications (Cardiopulmonary)
Tracheal Cuff Pressure and Postoperative Complications
This prospective observational study aims to identify risk factors for tracheal mucosal injuries caused by orotracheal tube use during the intraoperative period in patients undergoing elective surgeries at the Hospital de…
- Trial name
- TCP-POC (NCT07264179)
- Where
- Brazil
- Volunteers
- 362 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hemoptysis, Pulmonary Embolism
Prevalence Of Pulmonary Embolism In Patients With HEmoptysis (POPEIHE)
Estimation of the incidence of pulmonary embolism in patients presenting to the Emergency Department with hemoptysis.
- Trial name
- POPEIHE (NCT06067997)
- Testing
- pulmonary embolism diagnosis
- Where
- Italy
- Volunteers
- 550 people
- Sponsor
- Società Italiana di Medicina di Emergenza-Urgenza
Tumor, Hemoptysis
Post Market Study to Collect Data for Software Recognizing the Anatomical Structures During Bronchoscopy.
The primary aim is to develop a software algorithm that has the capacity to detect the normal 18 anatomical structures of the lung by using the position of the scope during the bronchoscopy procedure and using existing…
- Conditions
- Tumor, Hemoptysis, Pulmonary Disease
- Trial name
- NCT04770675
- Testing
- Bronchoscopy
- Where
- Denmark
- Volunteers
- 833 people
- Sponsor
- Qmed Consulting A/S
Haemoptysis
The Utility of Radiotherapy in the Management of Haemoptysis Secondary to Aspergillomata and Structural Lung Diseases
The sequelae of tuberculosis are still the commonest causes of haemoptysis in the developing world, where life-threatening haemoptysis remains a common and not infrequently fatal medical emergency.
- Trial name
- NCT02878447
- Testing
- External beam radiotherapy
- Where
- South Africa
- Volunteers
- 40 people
- Sponsor
- University of Stellenbosch
Endobronchial Bleeding, Hemoptysis
The Efficacy of Tranexamic Acid and Adrenaline to Control Endobronchial Bleeding
During bronchoscopy (a procedure using a thin, flexible camera to look inside the airways), doctors sometimes take small tissue samples (biopsies) to diagnose lung conditions. This can cause bleeding in the airway.
- Trial name
- CATER (NCT07759089)
- Testing
- Adrenaline, Tranexamic Acid
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Inflammatory Lung Diseases, Hemoptysis
The Expression of Serum Angiogenesis Marker in Patients Presenting With Hemoptysis
Vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2) are major mediators of angiogenesis and are induced by tissue inflammation and hypoxia.
- Trial name
- NCT01171768
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Samsung Medical Center
Haemoptysis
Endobronchial Valves in Inoperable Patients With Haemoptysis
Massive haemoptysis is a life-threatening condition which is commonly seen in patients who have previously had pulmonary tuberculosis.
- Trial name
- NCT02816229
- Testing
- Insertion of endobronchial valve
- Volunteers
- 20 people
- Sponsor
- University of Stellenbosch
Hemoptysis, Perioperative Complication
Study of the Role of Hemostasis in Perioperative Anaphylaxis
Anaphylaxis is a severe and life-threatening complication during the perioperative period. Perioperative anaphylaxis is still associated with a significant mortality despite quick and efficient management using epinephrine, the…
- Conditions
- Hemoptysis, Perioperative Complication, Anaphylaxis
- Trial name
- HEMOCANOPE (NCT04825158)
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Hemoptysis, NEBULIZATION
Tranexamic Acid : Nebulization vs IV Route for Hemoptysis
This study compares the effect of tranexamic acid on hemoptysis when given through the conventional IV route and Through nebulization.
- Conditions
- Hemoptysis, NEBULIZATION, Tranexamic Acid
- Trial name
- NCT07212452
- Testing
- Tranexamic Acid (TXA)
- Where
- Pakistan
- Volunteers
- 172 people
- Sponsor
- University of Health Sciences Lahore
Hemoptysis, Haemoptysis
Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis
The study consist of a retrospective analysis of the etiologies, investigations and outcomes of patients presenting between 2005 to 2010 with hemoptysis in a North-American Tertiary center.
- Conditions
- Hemoptysis, Haemoptysis, Lung Disease, Pneumonia
- Trial name
- NCT02913365
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- Université de Sherbrooke
Lung Transplant; Complications, Mechanical, Lung Transplant; Complications
Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies
Bleeding poses potential for significant complication after transbronchial lung biopsies. The investigators hypothesize that prophylactic intrabronchial instillation of topical epinephrine will reduce the likelihood of bleeding.
- Conditions
- Lung Transplant; Complications, Mechanical, Lung Transplant; Complications, Bleeding, Hemoptysis
- Trial name
- PROPHET (NCT03126968)
- Testing
- Topical epinephrine
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Maryland, Baltimore
Pneumothorax Iatrogenic Postprocedural, Air Embolism as A Complication of Medical Care
Complications After CT-guided Lung Biopsies at St. Olavs Hospital
At St. Olavs Hospital, a prospective collection of data on complications related to CT-guided lung biopsies has been conducted over several years as part of quality control study.
- Conditions
- Pneumothorax Iatrogenic Postprocedural, Air Embolism as A Complication of Medical Care, Hemoptysis
- Trial name
- KELSO (NCT07528170)
- Testing
- CT-guided needle biopsy of lung nodule
- Volunteers
- 1,200 people
- Sponsor
- St. Olavs Hospital
Hemoptysis
An Exploratory Study on the Application of Transarterial CT Angiography in the Interventional Treatment of Massive Hemoptysis
This is a single-arm, exploratory study to evaluate the value of transarterial CT angiography applying Nexaris Angio-CT in the interventional treatment of massive hemoptysis
- Trial name
- NCT05786781
- Testing
- Transarterial CT angiography
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Hemoptysis
ACid Tranexamic or Terlipressin for Initial Emergency Treatment of Mild to seVere hEmoptysis: a Randomized Trial.
The study aims is to verify the hypothetize that inhaled Tranexamic Acid (TXA) or Terlipressin (TER) will be associated with an increase in the rapid control of hemoptysis without side-effects.
- Trial name
- ACTIVE (NCT04961528)
- Testing
- Tranexamic Acid 500 MG, Terlipressin
- Where
- France
- Volunteers
- 315 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adenosquamous Cell Lung Cancer, Drug/Agent Toxicity by Tissue/Organ
Radiation Therapy, Bevacizumab, Paclitaxel, and Carboplatin in Treating Patients With Unresectable Stage IIIB or Stage IV Non-Small Cell Lung Cancer at High Risk for Hemoptysis Caused by Bevacizumab
This phase II trial is studying the side effects and how well giving radiation therapy together with bevacizumab, paclitaxel, and carboplatin works in treating patients with unresectable stage IIIB or stage IV non-small cell lung…
- Conditions
- Adenosquamous Cell Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, Hemoptysis, Squamous Cell Lung Cancer
- Trial name
- NCT00387374
- Testing
- bevacizumab, paclitaxel, carboplatin
- Volunteers
- 72 people
- Sponsor
- National Cancer Institute (NCI)
Hemoptysis
Chinese Hemoptysis Registry Study
This is a prospective, multicenter, observational registry study of hemoptysis in China. Hospitalized patients with active hemoptysis who undergo vascular interventional diagnosis and therapy will be consecutively enrolled from…
- Trial name
- CHORE (NCT07833878)
- Testing
- Not applicable. This is an observational patient registry. All clinical procedures (including bronchial artery embolization) are part of routine medical care and are not assigned as study intervention
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Qiu Jipeng
Hemorrhage, Gastrointestinal Hemorrhage
HISTOACRYL® Used for Embolization of Thoracoabdominal Artery Bleeding
This observational study will collect information from adult patients in Japan who are treated with Histoacryl® to stop bleeding from arteries in the chest or abdomen, in order to better understand how well the treatment works…
- Conditions
- Hemorrhage, Gastrointestinal Hemorrhage, Hemoptysis, Postpartum Hemorrhage
- Trial name
- HEAL (NCT07753005)
- Testing
- Embolization therapy
- Where
- 11 sites in Japan
- Volunteers
- 176 people
- Sponsor
- Aesculap AG
Lung Cancer, Tuberculosis
Epidemiology and Diagnosis of Haemoptysis: a Multicenter Study
Haemoptysis is the coughing up of blood originating from the respiratory tract. It is a common and worrying clinical symptom which can be due to different aetiologies including lung cancer, tuberculosis, COPD, bronchiectasis…
- Conditions
- Lung Cancer, Tuberculosis, Bronchiectasis, Pneumonia
- Trial name
- NCT02045394
- Testing
- Chest X-ray, computed tomography of the chest, Bronchoscopy
- Where
- 6 sites in Italy
- Volunteers
- 610 people
- Sponsor
- University of Milan