Clinical trials: Hemiplegia and Hemiparesis, open to volunteers
Stroke, Acute, Stroke, Ischemic
Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute/Subacute Phase (Month 1 to 4)
The present clinical investigation - EarlyExo, is an interventional, international, multicentric, prospective, single-blinded randomized controlled trial.
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke, Subacute, Stroke Hemorrhagic
- Trial name
- EarlyExo (NCT06107010)
- Testing
- Use of the Atalante exoskeleton
- Where
- 5 sites in France, Germany and 1 more
- Volunteers
- 66 people
- Sponsor
- Wandercraft
Stroke, Chronic Stroke
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke.
- Conditions
- Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH)
- Trial name
- PHATHOM (NCT07053917)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
STROKE, Rehabilitation Outcome
Prospective Evaluation of Atrial Fibrillation-Related Stroke Patients in Rehabilitation Program (PEARL), an Observational Cohort Study
The goal of this observational study is to determine if rehabilitation program intensity impacts functional recovery and specific needs in adult ischemic stroke patients who require inpatient rehabilitation.
- Conditions
- STROKE, Rehabilitation Outcome, Brain Disease, Cardiovascular Disease Acute
- Trial name
- PEARL (NCT07253974)
- Testing
- Rehabilitation program based on Physiotherapy, occupational therapy and swallow and language therapy
- Where
- Spain
- Volunteers
- 213 people
- Sponsor
- Parc de Salut Mar
Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis), Gait Disorder
Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust
The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.
- Trial name
- ISOWALK (NCT05887440)
- Testing
- isokinetic strength training of knee extensor and flexor muscles
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Rennes University Hospital
Stroke, Ischemic, Stroke Hemorrhagic
Utility of CC7 Transfer in Stroke Subtypes
The purpose of this study is to evaluate the limb functional improvement after contralateral C7 root transfer in stroke patients.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Spastic Hemiparesis
- Trial name
- NCT06001736
- Testing
- Contralateral C7 root transfer for the treatment of spastic hemiparesis.
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Stroke, Hemiplegia and/or Hemiparesis Following Stroke
The Effect of Virtual Reality Therapy on Upper Extremity Functions in Subacute Stroke Patients Receiving Rehabilitation
Stroke ranks second among the leading causes of death worldwide and third among the causes of disability. In stroke patients, motor impairment typically affects facial movements and the upper and lower extremities unilaterally.
- Trial name
- NCT07299162
- Testing
- Virtual Reality, Conventional rehabilitation, Action observation therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Stroke Patients With Hemiplegia or Hemiparesis in the Subacute Stage
The Effect of Combined Transcranial Pulse Current Stimulation (tPCS) and Transcutaneous Electrical Nerve Stimulation (TENS) on Lower Limb Motor Function in Subacute to Chronic Stroke Patients With Hemiplegia (COMPENSATOR-Stroke)
The goal of this study is to evaluate the effects of high frequency tPCS + TENS compared to Sham device stimulation + TENS (Control) in lower limb motor function recovery in stroke patients with hemiplegia or hemiparesis in the…
- Trial name
- COMPENSATOR (NCT06999876)
- Testing
- The AscenZ-VIII Stimulator (Investigational Medical Device)
- Where
- 2 sites in Singapore
- Volunteers
- 90 people
- Sponsor
- National University Health System, Singapore
Traumatic Brain Injury, Traumatic Brain Injury (TBI)
Spinal Stimulation and Gait Training to Improve Mobility in TBI
The purpose of this research study is to assess the effects of receiving transcutaneous spinal stimulation while performing walking exercises compared to completing walking exercises without spinal stimulation for individuals…
- Conditions
- Traumatic Brain Injury, Traumatic Brain Injury (TBI), Hemiplegia and Hemiparesis
- Trial name
- DOD SS (NCT06886152)
- Testing
- Transcutaneous Spinal Cord Stimulation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Hemiplegia and/or Hemiparesis Following Stroke, Anterior Circulation Stroke of Uncertain Pathology
Effect of Transcutaneous Electrical Nerve Stimulation on Post-stroke Patients
The subjects will be asked to attend minimum 15 separate sessions, 6 for testing changes in reflex behaviors, 3 for testing changes in the influence of descending motor tracts on spinal motor neurons, 3 for each testing…
- Trial name
- TENS (NCT06541015)
- Testing
- InTENSity 10 TENS Stimulator
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Stroke, Hemiparesis After Stroke
Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower…
- Conditions
- Stroke, Hemiparesis After Stroke, Chronic Stroke Patients, Hemiplegia
- Trial name
- NIMBLE (NCT07073235)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Danderyd Hospital
Hemiplegia, Hemiparesis
Evaluation of the Safety and Performance of the AWAKE Device in Patients With Hemiplegia or Hemiparesis Secondary to Stroke (ACV).
Stroke is a leading cause of disability in adults, with gait impairment being a key functional limitation. Although lower limb exoskeletons are used in rehabilitation, the available evidence focuses on bilateral devices used in…
- Trial name
- VAWAKE (NCT07867847)
- Testing
- Bionic System (AWAKE)
- Volunteers
- 20 people
- Sponsor
- Bionic Mobility Solutions, S.L.
Stroke, Hemiplegia
Immediate Effects of PETTLEP-Based AOMI on Upper Limb Kinematics in Stroke Survivors
The purpose of this study is to investigate the immediate effects of a mental practice technique, called Physical, Environment, Task, Timing, Learning, Emotion, Perspective (PETTLEP)-based Action Observation and Motor Imagery…
- Conditions
- Stroke, Hemiplegia, Hemiplegia and/or Hemiparesis Following Stroke
- Trial name
- NCT07507552
- Testing
- PETTLEP-based Action Observation and Motor Imagery (AOMI), Cognitive and Somatic Control Tasks
- Volunteers
- 28 people
- Sponsor
- Istinye University
Stroke, Hemiplegia
Effects of Intermitted Theta Burst Stimulation (iTBS) on Motor Recovery of Upper Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of upper…
- Conditions
- Stroke, Hemiplegia, Hemiparesis After Stroke, Hand Functionality
- Trial name
- NIMBLE (NCT07073248)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Danderyd Hospital
Stroke, Hemiparesis
Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting
Stroke is a leading cause of long-term disability worldwide, with upper-limb impairment representing a major determinant of functional limitation and reduced independence.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Paresis, Motor Impairment
- Trial name
- ROBOHOME (NCT07590349)
- Testing
- Robotic-Assisted Telerehabilitation Virtual Reality-Based Telerehabilitation, Virtual reality-based rehabilitation platform without robotic assistance
- Volunteers
- 70 people
- Sponsor
- University of Campania Luigi Vanvitelli
Stroke, Hemiplegia and Hemiparesis
The Efficacy of Additional Motor Training Dosage During the Early Stages Post Stroke on the Upper Extremity Recovery
Intervention abstract Background: Stroke is the leading cause of long-term disability, and the second leading cause of death in the western world.
- Trial name
- EFODIN (NCT07056049)
- Testing
- High dosage, high intensity motor rehabilitation
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Adi Negev-Nahalat Eran
Stroke, Autonomic Dysfunction
Repetitive Transcranial Magnetic Stimulation in Cardiac Autonomic Dysfunction
The aim of this study is to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) added to conventional neurological rehabilitation on heart rate variability (HRV), quality of life, upper extremity muscle…
- Conditions
- Stroke, Autonomic Dysfunction, Hemiparesis
- Trial name
- NCT07482501
- Testing
- rTMS M1 Motor Cortex Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Afyonkarahisar Health Sciences University
Hemiplegia and/or Hemiparesis Following Stroke
High-Intensity Laser Therapy in Hemiplegic Shoulder Pain
This randomized, sham-controlled clinical trial aims to evaluate the effectiveness of high-intensity laser therapy (HILT) combined with exercise on pain, functional status, disability, and ultrasonographic findings in patients…
- Trial name
- NCT07501416
- Testing
- High-Intensity Laser Therapy (HILT), Exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
Hemiplegia, Cerebral Palsy Spastic Hemiplegic
Arm More + Camp: An Implementation Study
Our primary aim is to evaluate the implementation cost of a full day modified constraint induced movement therapy camp for children with hemiparesis.
- Conditions
- Hemiplegia, Cerebral Palsy Spastic Hemiplegic, Acquired Brain Injury (Including Stroke)
- Trial name
- NCT07065916
- Testing
- Modified Constraint Induced Movement Therapy
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary