Clinical trials: Hemiparesis After Stroke
Stroke
Premotor Cortex: A New Target for Stroke Motor Rehabilitation
The goal of the study is to determine the effect of repetitive transcranial magnetic stimulation (rTMS) over the premotor cortex on training-related improvements in motor performance and associated neural plasticity.
- Trial name
- NCT02565199
- Testing
- rTMS Over Contralateral Hemisphere of Premotor Cortex, rTMS Over Ipsilateral Hemisphere of Premotor Cortex, Control 1: rTMS Timed 400 ms After Movement-related EMG
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke, Hemiparesis
Retraining the Walking Pattern After Stroke
The purpose of the study is to determine the effects of pairing gait training with different forms of visual feedback about leg movements in individual post-stroke to modify/normalize their gait pattern over time.
- Trial name
- NCT03813342
- Testing
- Gait training with visual feedback of joint kinematics
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Stroke with Hemiparesis, Stroke
Impact of the BOOST GAIT Program on Gait Recovery and Functional Mobility After Stroke
The overarching goal is to determine if the BOOST GAIT program can improve functional mobility in patients with stroke who are undergoing inpatient rehabilitation and have some walking function, through the application of…
- Trial name
- BOOST GAIT (NCT06612359)
- Testing
- BOOST GAIT Program
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Hasselt University
Spasticity as Sequela of Stroke, Stroke
Transcutaneous Spinal and Peripheral Stimulation and Wrist Robotic Therapy for Patients With Spastic Stroke
The purpose of this study is to investigate if two courses of five consecutive sessions of noninvasive spinal stimulation paired with peripheral nerve stimulation at the forearm provided by an investigational device (Doublestim™/…
- Conditions
- Spasticity as Sequela of Stroke, Stroke, Stroke Sequelae, Hemiplegia, Spastic
- Trial name
- NCT04113525
- Testing
- MyoRegulator™ System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Northwell Health
Stroke With Hemiparesis
Home-based Graded Repetitive Arm Supplementary Program for Quality of Life and Functional Upper Limb Recovery
In post-stroke rehabilitation of the affected upper limb, increasing treatment intensity has been shown to lead to better outcomes compared to conventional approaches with fewer hours of therapy per day and week.
- Trial name
- REC-HOMEGRASP (NCT07146789)
- Testing
- occupational therapy combined with HomeGRASP program, occupational therapy
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Hemiparesis; Poststroke/CVA
Improving Arm Function Using Wearable Exoskeletons
The goal of this clinical trial is to compare arm and hand function with and without assistance from a wearable exoskeleton in individuals with neurological injury from a single stroke.
- Trial name
- NCT05951491
- Testing
- Wearable Shoulder Exoskeleton, Wearable Hand Exoskeleton
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Idaho
Stroke, Chronic Stroke
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke.
- Conditions
- Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH)
- Trial name
- PHATHOM (NCT07053917)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Hemiparesis
Post-stroke Motor Rehabilitation Using Functional Near-infrared Spectroscopy-based Brain-computer-interface
Chronic stroke survivors suffering from weaknesses or movement difficulties in their hand/arm are provided a system to aid in at-home rehabilitation for 6 weeks.
- Trial name
- fNIRS-PROMOTE (NCT05258591)
- Testing
- Axem Home
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Axem Neurotechnology Inc.
Stroke, Hemiparesis
Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting
Stroke is a leading cause of long-term disability worldwide, with upper-limb impairment representing a major determinant of functional limitation and reduced independence.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Paresis, Motor Impairment
- Trial name
- ROBOHOME (NCT07590349)
- Testing
- Robotic-Assisted Telerehabilitation Virtual Reality-Based Telerehabilitation, Virtual reality-based rehabilitation platform without robotic assistance
- Volunteers
- 70 people
- Sponsor
- University of Campania Luigi Vanvitelli
Hemiparesis After Stroke
Boccia Exercises and Upper Limb Muscle Adaptations in Hemiparetic Individuals
This study investigates whether adding Boccia exercises to conventional rehabilitation improves upper extremity muscle thickness and grip strength in individuals with hemiparesis following stroke.
- Trial name
- NCT07254273
- Testing
- Boccia exercise, physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Bayburt University
Stroke, Cerebrovascular Accident
Spinal Plasticity to Enhance Motor Retraining After Stroke
The objective of this project is to study the effects of an emerging noninvasive neuromodulation strategy in human stroke survivors with movement-related disability.
- Conditions
- Stroke, Cerebrovascular Accident, Hemiparesis
- Trial name
- NCT03645122
- Testing
- Paired corticospinal-motoneuronal stimulation (PCMS)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Efficacy of Music-Based Telerehabilitation After Stroke
The goal of this clinical trial is to learn if a music-based telerehabilitation intervention implemented at home works to treat different kinds of neurological deficits caused by stroke.
- Trial name
- NCT06804304
- Testing
- Music-based telerehabilitation
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Teppo Sarkamo
Post-stroke Upper Limb Hemiparesis, Repetitive Transcranial Magnetic Stimulation (rTMS)
Repetitive Transcranial Magnetic Stimulation Combined With Bimanual Therapy for Upper Limb Stroke Rehabilitation
The goal of this clinical trial is to evaluate whether combining repetitive transcranial magnetic stimulation (rTMS) with machine-assisted bimanual therapy (BT) can improve upper limb function in stroke patients.
- Conditions
- Post-stroke Upper Limb Hemiparesis, Repetitive Transcranial Magnetic Stimulation (rTMS), Bimanual Therapy, Neuromodulation
- Trial name
- NCT07054424
- Testing
- Conventional occupation therapy, stretching exercise, rTMS
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Study of Neurophysiological Markers of Motor Recovery in Post-stroke Patients.
The aim of the study was to explore potential pathways for recovery and adaptation of neural pathways after stroke by examining electrical activity of the brain cortex and cortico-spinal excitability using transcranial magnetic…
- Trial name
- NCT06386627
- Testing
- Stimulus response task, Transcranial magnetic stimulation
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Stroke, Hemiparesis
Sensorimotor Arm Rehabilitation After Stroke
Hemiparesis is a frequently observed symptom of stroke. There are various therapy options that are used in the rehabilitation of patients.
- Trial name
- TAB-APP (NCT05590988)
- Testing
- Tablet-based training, ergotherapeutic training
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Upper Extremity Weakness, Stroke
A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis
The primary purpose of this study is to establish that application of a Sequential Compression Device (SCD) and lower extremity (LE) sleeve applied to a hemi-paretic upper extremity is safe.
- Trial name
- NCT05535257
- Testing
- Sequential Compression Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Stroke With Hemiparesis
Strategies for Recovery of Dexterity Post Stroke
Motor learning can be affected by the sensory difficulties that may be experienced as a result of a stroke. This study will help us better understand what kinds of sensory information can help with the re-learning of grasping…
- Trial name
- NCT01977027
- Testing
- Alternate Hand Training or Affected Hand Training
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Stroke, Hemiparesis After Stroke
Multimodal Sensory Feedback and Mirror Therapy for Stroke Rehabilitation
The goal of this clinical trial is to investigate the clinical and neurophysiological effects of a novel multimodal sensory feedback mirror therapy in stroke survivors with upper extremity hemiparesis , aged between 20 and 85…
- Trial name
- NCT07426354
- Testing
- MAF-MT: Multimodal Augmeneted Mirror Therapy, Traditional Mirror Therapy, MVF-MT: Digital Mirror Visual Feedback Mirror Therapy
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- Asia University
Hemiparesis, Stroke Sequelae
Neural Mechanisms of Motor Recovery With Technology Assisted Training
Stroke is a leading cause of disability that often impairs arm function and activities of daily living. The costs of rehabilitation are significant and practical constraints often limit therapy to the first few months after…
- Trial name
- NCT05560867
- Testing
- robot-assisted training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Maryland, Baltimore
Foot Drop, Stroke
TREAT Foot Drop After Stroke With Ankle Robot
Researchers at the University of Maryland Rehabilitation and Orthopaedic Institute are looking for individuals who have suffered a stroke and have leg and ankle weakness (foot-drop), to participate in a pilot study to examine the…
- Conditions
- Foot Drop, Stroke, Hemiparesis
- Trial name
- TREAT (NCT04137809)
- Testing
- AMBLE
- Where
- United States
- Sponsor
- NextStep Robotics Inc.