Clinical trials: Hematology, active
Hematology, Diffused Large B Cell Lymphoma
A Multicenter Observational Study to Understand the Clinical Characteristics, Treatment Patterns and Access to Novel Therapies of Patients With Diffuse Large B-Cell Lymphoma in the MEA Region
Non-Hodgkin lymphoma (NHL) is the most common hematologic malignancy, with over 80,500 estimated new cases diagnosed in the United States in 20231.
- Trial name
- DOMAIN (NCT07065344)
- Where
- 21 sites in Egypt, Iraq and 8 more
- Volunteers
- 500 people
- Sponsor
- AstraZeneca
Medical Oncology, Hematology
Onco-haematology Vigilance Card
The objective of this study is to show the interest of setting up a drug vigilance card in Oncology in order to reinforce patient safety, develop compliance and avoid drug interactions when the patient consults town professionals…
- Conditions
- Medical Oncology, Hematology, Molecular Targeted Therapies
- Trial name
- THERANOVA-LIM (NCT04931329)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Limoges
Pediatric Hematology, Pediatric Oncology
Effect of Hand Puppet and Squeeze Toys on IV Placement in Pediatric Oncology Patients
This randomized controlled trial investigates hand puppet and squeeze toy techniques to reduce fear, emotional distress, and procedure time, and improve IV catheter placement success in 90 pediatric hematology-oncology patients…
- Trial name
- NCT07493018
- Testing
- Performing a Hand Puppet to Music, Hand Squeezing Soft Toy (Squishy)
- Volunteers
- 90 people
- Sponsor
- Akdeniz University
Red Blood Cell Transfusions, Sex Differences
Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes
Red blood cell (RBC) transfusions are selected based upon matching donor and recipient blood group: donor and recipient sex are not considered when selecting blood for transfusion.
- Conditions
- Red Blood Cell Transfusions, Sex Differences, Health Services, Critically Ill Intensive Care Unit Patients
- Trial name
- SexMATTERS RCT (NCT06840756)
- Testing
- Sex-mismatched red blood cell transfusions, Sex-matched red blood cell transfusions
- Where
- 8 sites in Canada
- Volunteers
- 11,082 people
- Sponsor
- Michelle Zeller
Oncology, Hematology
Goal Attainment Scale in Transplantation
The primary aim of this monocentric randomised controlled study is to evaluate the impact of using GAS to maintain the functional abilities of children and adolescents undergoing TCSE.
- Trial name
- GAST (NCT07372690)
- Testing
- GAS group, control group
- Where
- Italy
- Volunteers
- 176 people
- Sponsor
- Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna
Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma, CART Therapy
Pragmatic Geriatric Assessment Before CAR-T or Bispecific Antibody Therapy to Predict Side Effects and Outcomes in Older Patients (GA-ACT Trial)
CAR-T cell or bispecific antibody therapies are a new treatment option for adult patients with aggressive forms of lymphoma or so-called plasma cell diseases ('multiple myeloma', 'plasma cell myeloma') that could not be cured…
- Conditions
- Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma, CART Therapy, Bispecific Antibody, Geriatric Hematology
- Trial name
- GA-ACT (NCT07309497)
- Testing
- pragmatic geriatric assessment
- Where
- 2 sites in Switzerland
- Volunteers
- 208 people
- Sponsor
- University of Zurich
Pediatric Intensive Care Unit, Pediatric Immuno-hematology Department
Population Pharmacokinetics of Anti-infectives in Critically Ill Children
Concentrations and effects of anti-infectives in critically ill children are unpredictable and the risk of under-exposure may be associated with poor clinical outcomes.
- Trial name
- OPTIMOME (NCT02539407)
- Testing
- Pharmacokinetics
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer, Post-cancer
Correlation Between Ultrasound-assessed Quadriceps Muscle Mass and Baseline Whole-body Densitometry Muscle Index in the Post-cancer Population (JUMP Research II)
Therapeutic advances in oncology have transformed the prognosis of cancer patients, placing a significant number of them either in a context of recovery or in prolonged remission close to a chronic disease.
- Conditions
- Cancer, Post-cancer, Hematology
- Trial name
- JUMPresearchII (NCT06007794)
- Testing
- JUMP group
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Hospices Civils de Lyon
Pediatric Cancer, Pediatric Hematology
IMPACT: IMplementation of Physical Activity for Children and Adolescents on Treatment
Physical activity can enhance well-being among youth diagnosed with oncological or hematological diseases. We developed a tailored, 1:1, online physical activity program (i.e., IMPACT), to promote physical activity in this…
- Trial name
- NCT04956133
- Testing
- Physical Activity
- Where
- 2 sites in Canada
- Volunteers
- 250 people
- Sponsor
- University of Calgary