Clinical trials: Heart Rate Monitoring, active
Cranial Neurosurgery
Heart Rate Variability and Processed EEG Features as Predictors of Postoperative Outcomes After Cranial Neurosurgery
Patients undergoing cranial neurosurgery face a high-risk postoperative period, particularly during emergence from anesthesia and early recovery in the post-anesthesia care unit (PACU).
- Trial name
- HERO-PACU (NCT07443072)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Fetal Distress With Antenatal Problem, Fetal Growth Retardation
Validation of Sensors for Long-term Non-Invasive Fetal Monitoring
A multidisciplinary team of a doctor and engineers have developed a new sensor that will be able to detect mothers' and babies' heartbeat and babies movements in late pregnancy.
- Trial name
- NCT06952777
- Testing
- Non-adhesive capacitively-coupled sensors
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Diabete Type 2, Heart Failure
Monitoring of the Sympathetic/Vagal Balance Through Multiparametric Analysis of Heart Rate Variability (HRV)
The autonomic nervous system (ANS) plays a crucial role in cardiovascular regulation by modulating heart rate in response to endogenous and environmental stimuli.
- Conditions
- Diabete Type 2, Heart Failure, Kidney Disease, Chronic, Cardiorenal Syndrome
- Trial name
- GLIFO-HRV (NCT07471802)
- Testing
- HOLTER ECG monitoring
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Vital Sign, Heart Rate
Validation Study on RENEW's Aingeal at KK Women's and Children's Hospital
This proposal describes the evaluation of a CE-marked, FDA cleared vital signs Surveillance Monitoring system within an adult in-patient setting KK Women's and Children's Hospital ("KKH"), the main tertiary women and children…
- Conditions
- Vital Sign, Heart Rate, Respiratory Rate
- Trial name
- RENEW (NCT03750318)
- Testing
- Vital sign monitoring
- Where
- Singapore
- Volunteers
- 39 people
- Sponsor
- KK Women's and Children's Hospital
Exercise Physiology, Nutritional Supplementation
Effects of Pre-Run Nutritional Supplements During a Fixed-Pace 5 km Treadmill Run
This study will examine how three commonly used pre-run nutritional supplements-caffeine, L-citrulline, and an exogenous ketone supplement-affect physiological and perceptual responses during a fixed-pace 5 km treadmill run in…
- Trial name
- NCT07854223
- Testing
- Caffeine, L-Citrulline, Exogenous Ketone (Beta-Hydroxybutyrate)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Pregnancy - Labor Monitoring, Labor and Childbirth
Wearable Ultrasound Patch in Parturients
This study will assess an investigational ultrasound patch placed on the maternal abdomen to noninvasively monitor uterine activity, obtain fetal images and physiologic measurements in labor.
- Conditions
- Pregnancy - Labor Monitoring, Labor and Childbirth, Fetal Heart Rate Tracing
- Trial name
- NCT07871903
- Testing
- wearable ultrasound patch
- Volunteers
- 40 people
- Sponsor
- Stanford University
Heart Rate Monitoring, Vagal Bradycardia
Heart Rate Variability and Early Cytokine Profile in Pediatric Adenotonsillectomy
This prospective observational cohort study will assess whether perioperative short-term heart rate variability (HRV) indices and early inflammatory cytokine levels are associated with respiratory and cardiac adverse events in…
- Conditions
- Heart Rate Monitoring, Vagal Bradycardia, Adenotonsillar Hypertrophy, Tonsillitis; Hypertrophic
- Trial name
- NCT07719439
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Duzce University
Burnout, Sleep Disturbance
Non-Invasive Sleep Monitoring for Burnout and Retention Risk in Postgraduate Nurses
Newly graduated nurses often experience high levels of psychological stress, sleep disturbance, fatigue, and burnout during the early transition into clinical practice.
- Conditions
- Burnout, Sleep Disturbance, Occupational Stress, Mental Health
- Trial name
- NCT07666633
- Testing
- Non-Invasive Sleep Monitoring
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Armed Forces General Hospital
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cesarean Section
Development of a Risk Prediction Model for Post-Spinal Anesthesia Hypotension During Cesarean Delivery Using Heart Rate, Blood Pressure, Perfusion Index, ECG Waveforms, and SpO₂ Waveforms
Spinal anesthesia is the preferred anesthetic technique for patients undergoing cesarean section. Compared with general anesthesia, spinal anesthesia offers multiple advantages.
- Trial name
- NCT07689825
- Testing
- Standard clinical spinal anesthesia and routine intraoperative monitoring
- Where
- China
- Volunteers
- 145 people
- Sponsor
- Peking University Shenzhen Hospital
Obstetrics
Autonomic Nervous System Intrapartum Monitoring to Prevent Neonatal Adverse Outcomes
Perinatal asphyxia affects 3 to 8 newborns per 1,000 births, with moderate or severe anoxic-ischemic encephalopathy occurring in 0.5 to 1 per 1,000 births.
- Trial name
- ANSINAO (NCT07409545)
- Testing
- Recording of fetal and maternal heart rate
- Volunteers
- 760 people
- Sponsor
- University Hospital, Lille
Rheumatoid Arthritis (RA)
HRV Variation in Rheumatoid Arthritis
The goal of this observational study is to determine the association between continuous Heart Rate Variability (HRV) measured by the Oura ring and Rheumatoid Arthritis (RA) disease activity.
- Trial name
- NCT07878975
- Testing
- Oura Ring
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Central Florida
Post-Traumatic Stress Disorder
Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD: A Signal Characterisation Pilot Study
This study examines whether a continuous wearable biosensor and a proprietary signal detection algorithm (JungleCODE, Open Medicine Studio) can detect and characterise the autonomic nervous system arc - a trajectory from a state…
- Trial name
- OMS-KAT (NCT07614581)
- Testing
- Continuous wearable physiological monitoring (EmbracePlus, Empatica), Ketamine-assisted therapy (independently arranged), Structured pre- and post-session interviews
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Adriaan Dirk van der Wart
Opioid Use Disorder, Opioid Withdrawal
Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder
IBO-CARE is a single-site Phase 1/2a study evaluating the safety, tolerability, feasibility and preliminary outcomes of medically supervised ibogaine with 12 months of recovery support in adults with moderate-to-severe opioid use…
- Conditions
- Opioid Use Disorder, Opioid Withdrawal, Substance Use Disorders
- Trial name
- IBO-CARE (NCT07871877)
- Testing
- Ibogaine Hydrochloride, Extended-release naltrexone injection, 380 mg, My-E-Health SENTINEL Digital Monitoring and Human-Gated Escalation Platform
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Clive Michelsen
Cardiac Rehabilitation, Cardiovascular Disease Prevention
Monitoring and Guidance of Physical Activity During the Maintenance Phase of Cardiac Rehabilitation: the Antwerp Activity Index
The goal of this clinical trial is to determine whether the AAI activity score can help cardiac rehabilitation patients adhere to physical activity guidelines after participating in an in-hospital cardiac rehabilitation program.
- Trial name
- AMAAI (NCT07211282)
- Testing
- Activity score
- Where
- 2 sites in Belgium
- Volunteers
- 318 people
- Sponsor
- University Hospital, Antwerp
Inflammatory Bowel Disease, Heart Rate Variability
Continuous HRV Monitoring for Predicting Response to Biologic Therapy in IBD
This is a prospective, multicenter, observational cohort study, which plans to enroll patients with active IBD who are scheduled to initiate IFX or VDZ treatment between October 2025 and October 2027 at Xijing Hospital, Tang-du…
- Conditions
- Inflammatory Bowel Disease, Heart Rate Variability, Biologics, Prediction
- Trial name
- NCT07475052
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Sleep, Infant，newborn
Clinical Effectiveness of Non-contact Heart Rate and Respiratory Rate Monitoring System
In this study, hospitalized neonates were taken as the focus of the study. The non-contact heart rate and respiratory rate monitoring system was used to measure heart rate, respiratory rate, sleep parameters, ECG monitor…
- Conditions
- Sleep, Infant，newborn, Vital Signs
- Trial name
- NCT06573203
- Testing
- Non-contact heart rate and respiratory rate monitoring system, Mindray ECG monitor, aEEG
- Where
- China
- Volunteers
- 70 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Sudden Unexplained Infant Death, Apnea of Newborn
Advanced Wireless Sensors for Neonatal Care in the Delivery Room
The goals of this observational study is to assess whether a new advanced wireless skin sensor vital sign monitoring system can effectively monitor the vital signs of healthy newborn infants (≥ 35 weeks gestational age).
- Conditions
- Sudden Unexplained Infant Death, Apnea of Newborn, Newborn Morbidity, Newborn Asphyxia
- Trial name
- AWARD (NCT06693817)
- Testing
- Wireless skin sensors vital sign monitoring system, Wired vital sign monitoring system
- Where
- 5 sites in Brazil, Canada and 2 more
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Guilherme Sant'Anna, MD
Preterm, Monitoring
The Use of the Bambi-Belt in Exteremly Preterm Infants: an Implementation Study.
This observational, non-interventional cohort study evaluates the clinical use of the Bambi Belt-a CE-certified, wireless device for non-invasive heart rate and respiration monitoring-in extremely preterm infants (<26 weeks…
- Trial name
- BB-EP (NCT07061366)
- Where
- 2 sites in Netherlands
- Volunteers
- 15 people
- Sponsor
- Maxima Medical Center
Monitoring, ECG
Clinical Performance and Usability of the Heart Rate and Impedance Respiration Monitor Cable
This study aims to evaluate the performance and usability of a new physiological monitoring technology by collecting data from subjects across different age groups to support device development and clinical evaluation.
- Conditions
- Monitoring, ECG, Electrocardiogram
- Trial name
- NCT07893405
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- GE Healthcare