Clinical trials: Healthy Subjects;Overweight or Obesity, open to volunteers
- Condition Healthy Subjects;Overweight or Obesity
- Status Open to volunteers
- Accepts healthy volunteers yes
Overweight and/or Obesity, Healthy Participants
A Study to Learn How Different Forms of the Study Medicine Called Berobenatide is Taken up Into the Blood in Adults With Overweight or Obesity
This is a single dose study to learn how safe and effective the study medicine is using different delivery systems for adults with overweight or obesity. Overweight or obesity means having more body fat than what is healthy.
- Trial name
- NCT07876531
- Testing
- Berobenatide
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Pfizer
Overweight, Obesity
A Study to Learn About the Study Medicine Called PF-08653944 in Otherwise Healthy Chinese Adults With Overweight or Obesity
The purpose of this study is to learn about: How PF-08653944 is changed and removed from the body after taken Safety of PF-08653944 The extent to which side effects can be tolerated after taking PF- 08653944 for the possible…
- Conditions
- Overweight, Obesity, Healthy Adults
- Trial name
- NCT07845513
- Testing
- PF-08653944
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy, Overweight and Obesity
Breathing & Blood Pressure
The purpose of this study is to determine the effect of obesity on cardiovascular responses during various breathing maneuvers.
- Trial name
- NCT05632406
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Florida State University
Healthy Subjects;Overweight or Obesity
A Phase 1 Study of GZC8072 Tablets Following a Single Dose in Healthy Study Participants and Multiple Doses in Obese/Overweight Study Participants
This trial is conducted in China. This study plans to include 2 parts, i.e., a single-dose study and a multiple-dose study: The single-dose study will be conducted in healthy adult participants to evaluate the safety…
- Trial name
- NCT07784699
- Testing
- GZC8072 Tablets
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Gan & Lee Pharmaceuticals.
Obesity, Healthy Volunteers
Physical and Behavioral Traits of Overweight and Obese Adults
This study will describe the phenotype (physical and behavioral traits) of overweight and obese people. It will characterize the hormones, metabolism, food preferences, fitness and physical activity levels, sleep patterns and…
- Trial name
- NCT00428987
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy Middle-aged Subjects, Obesity & Overweight
Stearic Acid and Endothelial Function
The goal of this clinical trial is to evaluate the postprandial and long-term effects of dietary stearic acid on vascular function in overweight or obese adult males and females aged 40-70 years.
- Trial name
- NCT07831603
- Testing
- High Palmitic Acid Diet, Stearic Acid Test Meal, Oleic Acid Test Meal
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Florida State University
Overweight, Healthy Participants
IBI3042 Study in Healthy Participants and Overweight or Obese Participants
This is a Phase 1 study of IBI3042, an investigational oral medicine being developed as a potential treatment for overweight and obesity. The study has two parts. Part A will evaluate single doses of IBI3042 in healthy adults.
- Conditions
- Overweight, Healthy Participants, Obesity
- Trial name
- NCT07793019
- Testing
- Orforglipron, IBI3042
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Dyslipidemia, Overweight and Obesity
Cottonseed Oil Versus Matched PUFA Effects
Cardiovascular disease risk factors, including higher BMIs and poor cholesterol profiles, are on the rise and contribute to the United States' growing disease burden.
- Conditions
- Dyslipidemia, Overweight and Obesity, Nutrition, Healthy
- Trial name
- NCT06382298
- Testing
- COTTONSEED OIL, MATCHED PUFA DIET, CONTROL
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Dyslipidemia, Overweight and Obesity
Intermittent Cottonseed Oil Consumption
Cardiovascular disease risk factors, including higher BMIs and poor cholesterol profiles, are on the rise and contribute to the United States' growing disease burden.
- Conditions
- Dyslipidemia, Overweight and Obesity, Nutrition, Healthy
- Trial name
- NCT07246408
- Testing
- CSO-30, CSO-20, Control
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Overweight, Obesity
A Study to Learn How the Study Medicine Called PF-08653945 is Taken up Into the Blood in Adults With Overweight or Obesity
This study is being done to learn how the study medicine affects the body. It will also assess how safe it is for people who take it. The researchers will use blood tests to measure how much medicine is in the blood.
- Conditions
- Overweight, Obesity, Healthy
- Trial name
- NCT07725809
- Testing
- PF-08653945
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Pfizer
Insulin Resistance, Type 2 Diabetes
Alpelisib Challenge Test (ACT)
The goal of this study is to test a potentially easier method for measuring how much insulin a person is capable of producing than the current gold-standard method, the "hyperglycemic clamp." Participants will come in for a…
- Conditions
- Insulin Resistance, Type 2 Diabetes, Obesity & Overweight, Healthy Adult Participants
- Trial name
- NCT07778524
- Testing
- Alpelisib 300 mg, Alpelisib Challenge Test (ACT): Mixed Meal Tolerance Test (MMTT) after taking alpelisib, Hyperglycemic clamp
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity & Overweight, Healthy Adult
Vitis Intervention Trial in Substrate Metabolism
Obesity is associated with reduced metabolic flexibility (MetFlex), the capacity to shift between carbohydrate and lipid oxidation in response to nutrient availability.
- Trial name
- VITIS (NCT07800988)
- Testing
- Freeze-Dried Whole Grape Powder
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy Participants Study, Overweight and Obese Adults
A Single and Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP6590 in Participants With Normal Weight, Overweight and Obesity
The goal of this clinical trial is to learn about the safety and tolerability of drug ZP6590 and to learn how the body processes the drug ZP6590 in adults.
- Conditions
- Healthy Participants Study, Overweight and Obese Adults, First in Man Study to Evaluate Initial Safety
- Trial name
- NCT07721597
- Testing
- ZP6590, solution for injection
- Where
- Germany
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Zealand Pharma
Healthy, Overweight (BMI > 25)
Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity
The goal of this 16-week randomised, placebo-controlled parallel study is to investigate the effect of a newly formed probiotic supplement on satiety and gut microbiota composition in healthy men and women with overweight or…
- Conditions
- Healthy, Overweight (BMI > 25), Overweight , Obesity, Male
- Trial name
- ProBiSat (NCT07715955)
- Testing
- Probiotic supplementation
- Where
- Netherlands
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Nutrition, Healthy, Dyslipidemia
Cardiometabolic Effects of the Recommended Daily Pecan Intake Dose
Cardiovascular disease risk factors, including higher BMIs and poor cholesterol profiles, are on the rise and contribute to the United States' growing disease burden.
- Conditions
- Nutrition, Healthy, Dyslipidemia, Overweight and Obesity
- Trial name
- NCT07696403
- Testing
- Pecan, Control
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Healthy, Obesity & Overweight
Growth Hormone Resistance of Beta-cells
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with impaired fasting glucose or impaired…
- Conditions
- Healthy, Obesity & Overweight, Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance (Prediabetes)
- Trial name
- GHRB-C (NCT07581860)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Nutrition, Healthy, Weight Loss
Effect of a Postbiotic Supplementation in Overweight and Obese Subjects: A Randomized Controlled Trial (PARABIOTICS-2).
The principal objective of this project is to evaluate the effect of a postbiotic supplement (inactivated microorganism) on body composition and other physiological and metabolic parameters related to excess body weight in…
- Conditions
- Nutrition, Healthy, Weight Loss, Overweight and Obesity
- Trial name
- PARABIOTICS-2 (NCT07165431)
- Testing
- Postbiotic + nutritional recommendations
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Overweight (BMI > 25), Obese But Otherwise Healthy Participants
Pistachio Snacking and Metabolic Flexibility
The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults.
- Conditions
- Overweight (BMI > 25), Obese But Otherwise Healthy Participants, Overweight or Obese, Obese Patients (BMI ≥ 30 kg/m²)
- Trial name
- NCT07340125
- Testing
- Pistachio
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Metabolic Syndrome, Obesity & Overweight
Breath Mass Spectrometry in Metabolic Syndrome and Metabolically Healthy Obesity
This study aims to develop a non-invasive diagnostic method for metabolic syndrome (MetS) and metabolically healthy obesity (MHO) through analysis of exhaled air.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, Metabolically Healthy Obesity
- Trial name
- NCT07330297
- Testing
- Breath Sampling and Analysis by PTR-MS
- Where
- Russia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Overweight and Obese Adults, Healthy
Sex Hormones as Regulators of the Age- and Sex-dependent Benefits of Caloric Restriction
Obesity increases the risk of type 2 diabetes, cardiovascular disease, and certain cancers, primarily due to elevated abdominal fat storage.
- Trial name
- GendAge (NCT07065643)
- Testing
- Phase 1 - Maintenance Diet, Phase 2 - Weight loss diet
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen