Clinical trials: Healthy Related, active
Healthy, 24-Hour Movement Guidelines
A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers
The goal of this clinical trial is to evaluate whether a home-based mHealth intervention can improve adherence to the 24-Hour Movement Guidelines in preschool-aged children (3-4 years old) who currently meet 0 or 1 of the…
- Conditions
- Healthy, 24-Hour Movement Guidelines, Feasibility Studies, Sleep
- Trial name
- Shining Star (NCT06667661)
- Testing
- Shining Star mHealth App
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Post Traumatic Stress Disorder, Depression
Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study
The purpose of the study is to evaluate a trauma informed digital multicomponent intervention design to improve health and safety outcomes for women with lifetime exposures to violence and co-occurring PTSD and/or depression…
- Conditions
- Post Traumatic Stress Disorder, Depression, Violence
- Trial name
- BSHAPE (NCT07227337)
- Testing
- BSHAPE, Control (general wellness)
- Where
- United States
- Volunteers
- 676 people
- Sponsor
- Johns Hopkins University
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Cancer Treatment
This phase III trial compares BBT-CI to HEAL for the reduction of insomnia in patients with stage I-IV cancer who are receiving cancer treatment. Cancer treatment can cause side effects such as sleep problems.
- Trial name
- BBT-II (NCT04829539)
- Testing
- Behavioral Intervention, Electronic Health Record Review, Quality-of-Life Assessment
- Where
- 153 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Rochester NCORP Research Base
Cardiovascular System, Respiratory System
Acute Health Effects of Traffic-Related Air Pollution Exposure
This study aims to assess the effects of acute exposure to traffic-related air pollution and the underlying mechanisms.
- Trial name
- NCT04153539
- Testing
- Walking along a busy road, Walking in a traffic-free park
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Fudan University
Lung Neoplasms, Psychological Distress
Association of Psychological Distress in Patients With Lung Cancer
Psychological distress is a multi-factorial experience of a psychological, social, spiritual, and/or physical nature that may interfere with one's ability to cope effectively with cancer, physical symptoms and treatment.
- Conditions
- Lung Neoplasms, Psychological Distress, Prognosis Factors, Lifestyle, Healthy
- Trial name
- Life-Score (NCT06218901)
- Testing
- immunotherapy, Targeted Therapy Agent
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai Chest Hospital
Healthy Participants Study, Contact Lens Wear
Assessment of the Relationship of Soft Contact Lens Fit and Power (Fit & Lens pOwer Soft lenSes)
The purpose of this study is to evaluate whether altering the optical power (in dioptres) of a contact lens affects both vision and lens fit.
- Conditions
- Healthy Participants Study, Contact Lens Wear, Contact Lens Fit
- Trial name
- FLOSS (NCT06745375)
- Testing
- contact lens wear
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Aston University
Water, Child Nutrition
Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families
The goal of this clinical trial is to understand if a cultural intervention for Navajo families will improve healthy beverage habits, health outcomes, and family cohesion.
- Conditions
- Water, Child Nutrition, Family Dynamics, Healthy Nutrition
- Trial name
- NCT06020027
- Testing
- Water is K'é
- Where
- United States
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Child Abuse, Child Neglect
Fostering Healthy Futures for Teens: An RCT
This study will implement and evaluate a mentoring program designed to promote positive youth development and reduce adverse outcomes among maltreated adolescents with open child welfare cases.
- Conditions
- Child Abuse, Child Neglect, Risk Behavior, Delinquency
- Trial name
- FHF-T (NCT03707366)
- Testing
- FHF-T
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Denver
Endoscopy, Digestive System, GLP1-R-related Disease
Evaluate the Detection of Retained Gastric Contents and Assess Safety Using the Flower Capsule Endoscopy in Healthy Individuals and GLP-1 Receptor Agonist Users
Clinical Study Overview Feasibility Study Plan (Study 1: Healthy Participants) Study 1- Confirming Flower capsule performance characteristics in detection of retained gastric contents greater than 1.5mL/kg in Healthy volunteers…
- Trial name
- NCT06927401
- Testing
- Flower
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Healthy Aging, Lifestyle-related Condition
Nicotinamide Riboside Supplementation and Exercise Training to Promote Healthy Longevity
The prevalence of age-related chronic diseases (like obesity, type 2 diabetes and cardiovascular diseases) is mounting worldwide, reaching pandemic proportions.
- Conditions
- Healthy Aging, Lifestyle-related Condition, Metabolic Diseases
- Trial name
- RESTORENAD (NCT06425042)
- Testing
- Nicotinamide Riboside (NR)
- Where
- Chile
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Finis Terrae University
Healthy Volunteers, Alcohol Use Disorder (AUD)
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
Background: Alcohol use disorder (AUD) is a leading cause of disease and death worldwide. New treatments for AUD are needed. Dopamine, a chemical that carries signals between brain cells, is thought to play a role in alcohol…
- Trial name
- NCT06484075
- Testing
- Siemens 3T PRISMA MR Scanner, PET/CT Scanner, Suvorexant
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Gastrointestinal Discomfort, Digestive Well Being
Evaluation of Gut-Related Well-Being and Mood Effects of a Daily Nutritional Food Ingredient From the Co-Fermentation of Fungal Mycelium (Pleurotus Pulmonarius) and Microalgae (Chlorella Vulgaris)
The purpose of the study is to evaluate the gut-related well-being and mood effects of a food ingredient obtained from the co-fermentation of oyster mushroom mycelium (Pleurotus pulmonarius), microalgae (Chlorella vulgaris), and…
- Conditions
- Gastrointestinal Discomfort, Digestive Well Being, Gut-related Symptoms
- Trial name
- NCT07407777
- Testing
- Food ingredient of oyster mushroom mycelium (Pleurotus pulmonarius) and microalgae (Chlorella vulgaris)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Koralo GmbH
Aging, Cellular Senescence
BIOANCIENT: Cohort of Centenarians in Navarra (1926-1927)
Demographic aging is a growing global challenge, driven by increasing life expectancy and declining birth rates, with projections indicating that more than 30% of the European population will be over 65 years old by 2100.
- Conditions
- Aging, Cellular Senescence, Biomarkers / Blood, Age-Related Diseases
- Trial name
- BIOANCIENT (NCT07707297)
- Where
- Spain
- Volunteers
- 333 people
- Sponsor
- Fundacion Miguel Servet
Healthy Adult Participants
Evaluation of BRC-002 Safety, Tolerability, Pharmacokinetics, and Food Effects in Healthy Participants
This study will evaluate the safety and tolerability of BRC-002, an investigational botanical drug from cannabis, in healthy adults.
- Trial name
- NCT07699120
- Testing
- BRC-002
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Biopharmaceutical Research Company
Homocystinuria
Proof of Concept Creatine Supplementation for Homocystinuria Study
Homocystinuria is a rare and inherited metabolic disorder, people with this condition don't have an enzyme needed to break down an amino acid called homocysteine.
- Trial name
- NCT06495567
- Testing
- Creatine, Dietary methionine tracer and protein intake
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Evaluate PK Profile, Evaluate PD Profile
A Study Testing the Effects of Different THC Doses on Psychological and Biological Function
The goal of this clinical trial is to learn how a investigational medicinal product (THC) affects psychological and physical responses in healthy adults with prior cannabis use experience.
- Conditions
- Evaluate PK Profile, Evaluate PD Profile, Healthy Adults, Safety and Tolerability in Healthy Volunteers
- Trial name
- DRATT (NCT07346690)
- Testing
- AVCN319301b (6mg), AVCN319301b (9mg), AVCN319301b (15mg)
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
MS-ResearchBiomarkerS
This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD).
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
- Trial name
- MS-ReBS (NCT05204459)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Healthy Participants
A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
The purpose of this study is to measure the pharmacokinetics (PK-how the body processes the study drug) of elecoglipron in healthy participants when taken by mouth as different formulations.
- Trial name
- NCT07723833
- Testing
- Elecoglipron Reference Formulation Dose A, Elecoglipron Test formulation 1 Dose A, Elecoglipron Reference Formulation Dose B
- Where
- 2 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP)
French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism Spectrum Disorders, and Healthy Controls
The goal of this study is to learn whether people living with severe psychiatric disorders can be grouped into more homogeneous subgroups, across usual diagnostic categories, based on two key dimensions: social withdrawal and…
- Conditions
- Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP), Bipolar Disorder (BD), Major Depressive Disorder (MDD
- Trial name
- FRENCH-MINDS (NCT07881016)
- Testing
- 3T Brain MRI, Biological Sampling, Clinical, Cognitive and Digital Assessments
- Where
- 17 sites in France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fondation FondaMental
Tobacco Dependence, Tobacco Smoking
Smoke-free Home Study in Subsidized Housing
Comprehensive smoke-free policies have the potential to substantially reduce tobacco-related disparities among populations in subsidized housing.
- Trial name
- NCT06170437
- Testing
- Smoke-free home resident intervention, Lay Health Worker coaching
- Where
- United States
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco