Clinical trials: Healthy Aging
Healthy Aging, Cognitive Decline
Cognitively Enriched Walking Program
Dementia currently affects more than 47 million people worldwide, its prevalence is forecasted to triple by 2050, and it has been reported to be one of the most costly disorders in Belgium.
- Conditions
- Healthy Aging, Cognitive Decline, Physical Inactivity
- Trial name
- NCT05500183
- Testing
- Cognitively enriched walking program, walking program
- Where
- 2 sites in Belgium
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University Ghent
Healthy Aging
Effects of Adding Force Control to a VR Game on Brain Activation
One of the major contributor for the lower quality of living in the aged population, is the reduction in hand function. To mitigate this, several virtual-reality based hand rehabilitation/training systems have been developed.
- Trial name
- NCT06412887
- Testing
- Virtual reality headset
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Healthy Ageing
Exploring Blood Flow Restriction as an Accessible Fitness Solution for Healthy Aging in Seniors
As people age, it can become harder to stay active and independent, especially when dealing with fatigue, joint pain, or other health problems.
- Trial name
- NCT07460609
- Testing
- Blood Flow Restriction Training Exercise, Health Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baylor University
Copd, Aging
Evaluation of Cardiac Variability After a Vitamine D Protocol and Whole Body Vibration
Evaluation of heart rate variability in time and frequency domains, in Chronic Obstructive Pulmonary Disease (COPD) after 03 months of vitamine D supplementation and whole body vibration (WBV) training
- Trial name
- NCT03679325
- Testing
- vitamine D, whole body vibration (WBV)
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Maíra F Pessoa
Exercise Training
Golf for Healthy Aging
Aging is associated with physiological declines that could impair the ability to perform activities of daily living and thus impair the quality of life of older adults.
- Trial name
- GHA (NCT03916887)
- Testing
- Golf instruction
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Serious Mental Illness, Older Adults
A Pilot Randomized Controlled Trial of the Hopeful and Healthy Living Program
The goal of this clinical trial is to learn if a novel psychosocial intervention is effective in helping adults over 50 with serious mental illness (SMI) increase their social connections and participate in more healthy lifestyle…
- Trial name
- (HHL) (NCT06940843)
- Testing
- Hopeful and Healthy Living (HHL)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus
Alcohol Related Disorders, Alcohol Drug Interactions
Healthy Living as You Age
Older persons who drink can be vulnerable to negative consequences of drinking. This trial aims to prevent harm from alcohol use in older adults through a program of screening and brief advice followed up with several health…
- Trial name
- HLAYA (NCT00379093)
- Testing
- Brief advice
- Where
- United States
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Sarcopenia, Atrophy
Leucine Supplementation in Elderly Men
In the present study the investigators aim to determine whether leucine supplementation can augment muscle mass and strength and improve body composition in healthy elderly men
- Conditions
- Sarcopenia, Atrophy, Aging
- Trial name
- NCT00807508
- Testing
- leucine
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Frailty in Older Adults, Intrinsic Capacity
Optimizing INtrinsic Capacity for Functional INdependence and to Impede FrailTY in Older Adults: Adaptation of the WHO-ICOPE for Healthy Ageing in Singapore
The goal of this intervention study is to screen and identify frailty and decline in intrinsic capacity (physical and mental capacities) in community-dwelling older adults in Singapore, and to evaluate whether early…
- Conditions
- Frailty in Older Adults, Intrinsic Capacity, Age-related Functional Decline, Healthy Ageing
- Trial name
- INFINITY-ICOPE (NCT07477561)
- Testing
- INFINITY-ICOPE programme
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Obesity, Aging
Environmentally Sustainable Nutrition for Older Adults (55+) With Obesity
The objective of the pilot study (feasibility study) is to assess the acceptability and feasibility of the developed 2EAT dietary treatment in obese older adults (55+).
- Trial name
- 2EAT (NCT06192732)
- Testing
- A more plant-based diet during weight loss
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Amsterdam University of Applied Sciences
Aging, Menopause
Microgreen Consumption for Healthy Aging
Microgreens are an emerging horticultural food crop with potential to improve human health. Previous research suggests they have broad consumer acceptance and that the micronutrient and bioactive compound levels are higher than…
- Conditions
- Aging, Menopause, Healthy
- Trial name
- NCT04239898
- Testing
- Red cabbage microgreens, Red beet microgreens
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Baseline/Control Phase, Intervention Phase
City For All Ages: Elderly-friendly City Services for Active and Healthy Ageing
Many city-dwelling elderly people can be greatly affected after a minor change in their living or health conditions. Mild Cognitive Impairment (MCI), early dementia and frailty are among the most common risks with deep…
- Trial name
- NCT06486935
- Testing
- IoT sensors, Traditional/Manual elderly monitoring
- Where
- 2 sites in France, Singapore
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Osteoarthritis, Knee, Myocardial Infarction, Acute
Algarve Active Ageing - Cardiac and Osteoarthritis Rehabilitation (A3-COR)
This study aims to develop, implement, and determines the effectiveness of a personalized medicine approach to each individual's phenotype, based on an innovative physical exercise program to promote the treatment of pain and…
- Conditions
- Osteoarthritis, Knee, Myocardial Infarction, Acute, Hypertension, Dyslipidemias
- Trial name
- A3-COR (NCT05999110)
- Testing
- Physical Exercise
- Where
- Portugal
- Volunteers
- 200 people
- Sponsor
- Associação para o Desenvolvimento do Centro Académico de Investigação e Formação Biomédica do Algarv
Healthy Aging, Health Care Utilization
Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 1
This study consists of three aims focused on examining the feasibility of adding the Geriatric Resources and Assessment for the Care of Elders (GRACE) model to structured Annual Wellness Visits (AWVs) to improve patient and…
- Conditions
- Healthy Aging, Health Care Utilization, Health-Related Behavior
- Trial name
- SPIRE1 (NCT06287801)
- Testing
- Annual Wellness Visit, Geriatric Resources and Assessment for the Care of Elders
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Massachusetts General Hospital
Healthy
Optimizing Combined Physical and Cognitive Activity in Community-Dwelling Older Adults.
This laboratory-based interventional study aims to determine which combination of physical activity intensity and cognitive activity difficulty yields the greatest acute cognitive benefits in community-dwelling older adults.
- Trial name
- CONSCIOUS (NCT07630272)
- Testing
- Light physical activity + easy cognitive activity, Light physical activity + challenging cognitive activity, Moderate physical activity + easy cognitive activity
- Where
- Belgium
- Volunteers
- 53 people
- Sponsor
- University Ghent
HIV, Inflammation
Exercise for Healthy Aging: The Impact of HIV and Aging on Physical Function and the Somatopause
The primary objective of this proposal is to compare a moderate or high intensity exercise intervention to improve physical function in persons aging with Human Immunodeficiency Virus (HIV).
- Conditions
- HIV, Inflammation, Obesity, Aging, Biological
- Trial name
- NCT02404792
- Testing
- High-intensity cardiovascular and resistance exercise, Moderate-intensity cardiovascular and resistance exercise
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Mild Dementia, Aging Well
Transcranial Pulse Stimulation of the Brain
This study will investigate transcranial pulse stimulation (TPS) as a method of enhancing cognitive and neural function. The study team will apply this low intensity, magnetically pulse technology to key brain regions in a…
- Trial name
- NCT05910619
- Testing
- Neurolith Transcranial Pulse Stimulation Active
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Older Men, Quality of Life
Effects of Resistance-Based Multicomponent Training Incorporating Respiratory Exercise on Diaphragm Thickness, Hepatic Attenuation, and Quality of Life in Healthy Older Men: A Randomized Controlled Trial
This randomized controlled trial investigated the effects of a four-week moderate-intensity resistance training program on diaphragm thickness, hepatic fat density, and health-related quality of life in healthy community-dwelling…
- Conditions
- Older Men, Quality of Life, Fatty Liver, Resistance Training
- Trial name
- RT-DIA-OLDER (NCT07449767)
- Testing
- Resistance Training Group (RT), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Healthy Aging, Cardiovascular Risk Factor
Exercise Pressor Reflex and Lifelong Training
Cardiovascular diseases represent the first mortality cause in the world. Ageing is considered as the most prominent risk factor for this kind of diseases. Also, hypertension represents one of the modifiable risk factors.
- Trial name
- LEaSTCaRe (NCT04013022)
- Testing
- Exercise History
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Exercise Training, Executive Function
Multi-Domain Exercise and Memory in Adults Relative to ApoE Genotype: A fMRI Study
The current project utilizes a single-blinded, double arm, 6-month randomized controlled trial to assess the effects of a multi-domain exercise program on memory performance, as well as cortical activities during the memory tasks…
- Conditions
- Exercise Training, Executive Function, Aging
- Trial name
- NCT05068271
- Testing
- Multi-Domain Exercise Program, Control Group
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University