Clinical trials: Health Care Costs
Musculoskeletal Diseases
Temple University Employees With Musculoskeletal Conditions Receive Physical Therapy to Treat Limitations Early
The purpose of this study is to determine whether seeing a physical therapist first compared with seeing a physician first is more clinically and cost effective in an occupational setting for acute musculoskeletal conditions.
- Trial name
- TEMPLE (NCT02272257)
- Testing
- Early Direct Access Physical Therapy, Physician management
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Temple University
Anesthesia, Inhalation; Vapor
Decreasing Environmental Impact and Costs of Using Inhalational Anesthetic With a Carbon Dioxide Membrane Filter System
Efficient inhalational anesthetic delivery requires the use of low-flow air and oxygen to reduce drug waste and minimize workspace contamination and environmental pollution.
- Trial name
- NCT04210570
- Testing
- Memsorb, Chemical granulate absorber
- Where
- Canada
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
Hypertension
Primary Care Strategies to Reduce High Blood Pressure: A Cluster Randomized Trial in Rural Bangladesh, Pakistan and Sri Lanka
Background: High blood pressure (BP) is the leading attributable risk for cardiovascular disease (CVD). In rural South Asia, hypertension remains to be a significant public health issue with sub-optimal rates of case finding and…
- Trial name
- COBRA-BPS (NCT02657746)
- Testing
- multi-component interventions
- Volunteers
- 2,550 people
- Sponsor
- Duke-NUS Graduate Medical School
Diabetes Mellitus, Type 2
Food and Education Effects on Diabetes Study
Low-income adults are disproportionately affected by diabetes, experiencing greater rates of diabetes, diabetes-related complications, and mortality.
- Trial name
- FEED (NCT04034511)
- Testing
- Medically-tailored meal delivery and medical nutrition therapy
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Johns Hopkins University
Ulcerative Colitis
A Study to Evaluate the Impact of Adalimumab on Quality of Life, Health Care Utilization and Costs of Ulcerative Colitis Subjects in the Usual Clinical Practice Setting
This study evaluated the quality of life (QOL) and economic impact of adalimumab treatment in participants with ulcerative colitis (UC).
- Trial name
- InspirAda (NCT01550965)
- Testing
- Adalimumab
- Volunteers
- 463 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Health Behavior
Study the Impact of the CommunityRx Program on Health, Self-care and Cost
CommunityRx is a health information technology-based innovation that, starting with the patient-health care provider encounter, facilitates self-care coordination for patients, caregivers, and providers.
- Trial name
- NCT02435511
- Testing
- HealtheRx
- Where
- United States
- Volunteers
- 411 people
- Sponsor
- University of Chicago
Bodily Distress Syndrome, Irritable Bowel
Health Care Use and Costs of Functional Somatic Disorders
The goal of this observational case-control study is to learn about direct healthcare use and costs of functional somatic disorders.
- Conditions
- Bodily Distress Syndrome, Irritable Bowel, Fibromyalgia, Chronic Widespread Pain
- Trial name
- NCT05811663
- Where
- Denmark
- Volunteers
- 9,656 people
- Sponsor
- Aarhus University Hospital
Hypercholesterolemia
Rosuvastatin ORBITAL Germany
The primary objective of the study is to compare the effect of rosuvastatin therapy plus compliance initiatives and rosuvastatin therapy alone for 12 months (52 weeks) on long-term cumulative direct and indirect disease-related…
- Trial name
- NCT00379249
- Testing
- Rosuvastatin
- Volunteers
- 8,000 people
- Sponsor
- AstraZeneca
Chronic Myeloid Leukemia (CML)
Healthcare Costs Among Patients With CML Receiving Dasatinib or Nilotinib in a Commercial and Medicare Population
The purpose of this study is to examine the healthcare costs among patients with CML receiving dasatinib or nilotinib as first line therapy in a commercially or Medicare insured population.
- Trial name
- NCT02363868
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Bristol-Myers Squibb
Metastatic Breast Cancer
Description of Treatment Patterns and Description and Comparison of Healthcare Resource Utilization and Costs of Women With Metastatic HR+/HER2- Breast Cancer Treated With CDK4/6 Inhibitors
The study was an observational, retrospective cohort design, using US administrative insurance claims data, to better understand Healthcare resource utilization (HRU) and healthcare costs among women with mBC initiated on a…
- Trial name
- NCT05153135
- Testing
- Ribociclib, Palbociclib, Abemaciclib
- Where
- United States
- Volunteers
- 4,320 people
- Sponsor
- Novartis Pharmaceuticals
Glioblastoma, Radionecrosis of Brain
FET-PET-Guided Management of Pseudoprogression in Glioblastoma
The goal of this diagnostic randomised clinical trial is to determine, in glioblastoma patients with diagnostic uncertainty between pseudoprogression and tumor progression on follow-up MRI after chemoradiation, the added value of…
- Trial name
- FET-POPPING (NCT06480721)
- Testing
- Clinical management based on the index MRI and an additional [¹⁸F] FET PET scan
- Where
- 8 sites in Netherlands
- Volunteers
- 144 people
- Sponsor
- Veerle Ruijters
Back Pain, Chronic Pain
Improving Outcomes and Lowering Costs by Integration of Primary Care Providers and Pain Medicine Physicians for Pain Pts
This study will demonstrate that functional improvement measures over a 6-month period for chronic low back patients under the care of Primary Care Provider (PCP), using a therapeutic plan formulated initially by the Pain…
- Conditions
- Back Pain, Chronic Pain, Pain, Intractable
- Trial name
- NCT02484937
- Testing
- Group 2 (PCP Treatment), Group 1 (PMS Treatment)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rush University Medical Center
Sleep Apnea, Obstructive
Portable Monitoring for Diagnosis and Management of Sleep Apnea
This multi-site project compares compares the efficiency of a home-based portable monitoring strategy to a standard of care sleep laboratory-based strategy for the diagnosis and positive airway pressure treatment of obstructive…
- Trial name
- HomePAP (NCT00642486)
- Testing
- Portable (Embla Embletta X30 system and Respironic REMStar Auto M series with CFlex), Standard polysomnography (PSG)
- Where
- United States
- Volunteers
- 373 people
- Sponsor
- Case Western Reserve University
Diabetes Mellitus, Type 1
Telemedicine Program in Type 1 Diabetes and CSII
Diabetes mellitus is a chronic disease of high socio-health relevance for their clinical and economic implications (risk of complications, disability ...) (healthcare costs).
- Trial name
- NCT02790645
- Testing
- Group 2a. Telemedicine program, Group 1a. Control, Group 1b.Telemedicine program
- Volunteers
- 51 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Cerebrovascular Disorders
Improving Stroke Care in Greece in Terms of Management, Costs and Health Outcomes-
The main objectives of the proposed project are: 1. To provide essential data on acute stroke management (quality indicators) incorporating hard clinical outcomes that will contribute to an ongoing process of quality improvement…
- Trial name
- SUN4P (NCT04109612)
- Where
- 10 sites in Greece
- Volunteers
- 913 people
- Sponsor
- National and Kapodistrian University of Athens
Obesity
Quality of Life Outcomes and Economic Impacts of Bariatric Surgery
The purpose is to determine the economic, clinical and quality of life outcomes of bariatric surgery and describe the consequences of protracted wait-times (~ 2 years) for this procedure.
- Trial name
- NCT00850356
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Alberta
Uterine Cervical Neoplasms
Economic Evaluation of Three Populational Screening Strategies for Cervical Cancer
The aim of this study was to compare the effectiveness and the costs of three types of population interventions to increase the number of female participants in the screening programmes for cancer of the cervix carried out by…
- Trial name
- CRICERVA (NCT01373723)
- Testing
- Different alternatives to improve the coverage of the populational screening programmes of cervical cancer
- Where
- Spain
- Volunteers
- 20,994 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Internalizing Mental Health Symptoms, Allostatic Load
Students Rising Above: Offsetting the Health and Mental Health Costs of Resilience
Students who 'strive' to rise above significant stressors to achieve academic success are considered 'resilient'. However, youths' resilience in one domain (i.e.
- Conditions
- Internalizing Mental Health Symptoms, Allostatic Load, Health Complaints
- Trial name
- STRIVE (NCT05846282)
- Testing
- STRIVE, Study Skills
- Where
- United States
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Adolescent Idiopathic Scoliosis
Comparing Use of Radiographs Versus Patient Empowerment (CURVE)
Objective: To evaluate the (cost-)effectiveness of a new patient-empowered follow up (FU) protocol in patients with Adolescent idiopathic Scoliosis (AIS) that is based on patient-reported outcome measures (PROMs), self-assessment…
- Trial name
- CURVE (NCT05379127)
- Testing
- Patient-empowered follow up, Standard follow-up
- Where
- 23 sites in Netherlands
- Volunteers
- 812 people
- Sponsor
- Radboud University Medical Center
Schizophrenia Spectrum & Other Psychotic Disorders
PACT for Individuals With Serious Mental Illness
People with serious mental illness have difficulty making good use of primary care, and die, on average, years earlier than others in the population.
- Trial name
- SMI-PACT (NCT01668355)
- Testing
- Patient Aligned Care Team (PACT)
- Where
- 3 sites in United States
- Volunteers
- 331 people
- Sponsor
- VA Office of Research and Development