Clinical trials: Hazardous Behavior
Hazardous Drinking, Harmful Alcohol Use
Telephone-Based Acceptance and Commitment Therapy for Young Adult Hazardous Drinkers
The goal of this clinical trial is to learn if telephone-based Acceptance and Commitment Therapy (ACT) works to help young adults with hazardous or harmful alcohol use quit drinking.
- Trial name
- NCT07621822
- Testing
- Telephone-Based Acceptance and Commitment Therapy (ACT), Waitlist control with Telephone-Based Social Support
- Volunteers
- 288 people
- Sponsor
- The Hong Kong Polytechnic University
Hazardous Alcohol Use
PrEP and Alcohol - Enhancing HIV Pre-Exposure Prophylaxis (PrEP)
The present investigation entails a pilot randomized controlled trial to explore whether a stand-alone, alcohol-reduction, brief intervention (with a module on substance use and depression) would be feasible, acceptable, and…
- Trial name
- NCT05097430
- Testing
- Alcohol-focused brief intervention
- Where
- 3 sites in Canada
- Volunteers
- 122 people
- Sponsor
- Centre for Addiction and Mental Health
Alcohol-induced Disorders, Alcohol Drinking
Strengths-based Linkage to Alcohol Care (SLAC) for Hazardous Drinkers in Primary Care
This pilot study will determine the feasibility, acceptability, and efficacy of Strengths-based Linkage to Alcohol Care (SLAC; a behavioral intervention) to link Veterans, identified as hazardous drinkers in VHA primary care, to…
- Conditions
- Alcohol-induced Disorders, Alcohol Drinking, Mental Health
- Trial name
- NCT05023317
- Testing
- Strengths-based linkage to alcohol care, Usual care
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Drinking and Driving
Alcohol Impaired Driving: From the Laboratory to the Natural Environment
This project combined laboratory and ambulatory assessment (AA) methods to test decision making associated with alcohol impaired driving (AID).
- Trial name
- NCT03846050
- Testing
- BAC feedback/warning, No BAC feedback/warning
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Driving Impaired, Alcohol Intoxication
Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests
The overarching aim of this study is to examine the impact of acute cannabis and alcohol administration on driving performance, as well as identify methods for detecting driving under the influence of these substances.
- Conditions
- Driving Impaired, Alcohol Intoxication, Driving Under the Influence, Cannabis Intoxication
- Trial name
- NCT05273658
- Testing
- Cannabis, Alcohol
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alcohol; Harmful Use, Binge Drinking
Computerized Brief Alcohol Intervention (BI) for Binge Drinking HIV At-Risk and Infected Women
African American (AA) women are disproportionately affected by HIV/AIDs. The major risk factor for HIV acquisition among AA women is high-risk heterosexual sex, including unprotected vaginal and anal sex, and sex with a high-risk…
- Conditions
- Alcohol; Harmful Use, Binge Drinking, Risk Behavior, HIV Infection
- Trial name
- NCT01125371
- Testing
- Computerized brief alcohol intervention + IVR booster calls, Computerized brief alcohol intervention, Attention Control
- Where
- United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Binge Drinking, Alcohol Abuse
Cognitive Behavioral Treatment to Reduce Alcohol Use Among HIV-Infected Kenyans
This study will determine whether a cognitive behavioral intervention that demonstrates strong evidence in the U.S. of reducing alcohol use is effective when delivered by paraprofessionals in Kenya and compared against a usual…
- Conditions
- Binge Drinking, Alcohol Abuse, Alcohol Dependence, HIV Infections
- Trial name
- KHBS (NCT00792519)
- Testing
- HIV support group, CBT
- Where
- Kenya
- Volunteers
- 75 people
- Sponsor
- Brown University
Heavy Drinking, Driving Under the Influence
Adolescent Substance Use Prevention Intervention Research Study in Pediatric Primary Care
Our goal is to conduct a large multi-site randomized controlled trial (RCT) of a promising computer-facilitated Screening and clinician Brief Intervention (cSBI) system designed for delivery by pediatric primary care clinicians…
- Conditions
- Heavy Drinking, Driving Under the Influence, Riding With Driver Under the Influence
- Trial name
- ASPIRE (NCT04450966)
- Testing
- Computer-facilitated Screening and Brief Intervention
- Where
- 3 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Hazardous Drinking, Binge Drinking
A Stage 2 Cognitive-behavioral Trial: Reduce Alcohol First in Kenya Intervention
This study will determine whether a group cognitive-behavioral therapy intervention that demonstrates preliminary evidence of reducing alcohol use among HIV-infected outpatients in western Kenya is effective when compared against…
- Conditions
- Hazardous Drinking, Binge Drinking, HIV-infected
- Trial name
- RAFIKI (NCT01503255)
- Testing
- cognitive behavioral group therapy, health education group
- Where
- Kenya
- Volunteers
- 614 people
- Sponsor
- Brown University
Anesthesia, Spinal, Sedation, Conscious
Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
1. Adequate sedation with classical sedative agents, propofol 2. Sedation with propofol may induce paradoxical excitement response in heavy alcohol drinkers 3.
- Conditions
- Anesthesia, Spinal, Sedation, Conscious, Dexmedetomidine, Alcohol Drinking
- Trial name
- DEX (NCT02197403)
- Testing
- Dexmedetomidine, Propofol
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Chonnam National University Hospital
Alcohol Drinking, Alcohol; Harmful Use
Reducing Hazardous Alcohol Use in Social Networks Using Targeted Intervention: 21 Rising
The primary goal of this study is to determine whether change in alcohol use among college students can be transmitted through social network ties to other members in the network.
- Trial name
- NCT04147520
- Testing
- Brief Motivational Interview
- Where
- United States
- Volunteers
- 1,475 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcoholic Intoxication
Behavior and Driving Safety Study II
The purpose of this study is to determine whether brief motivational interviews reduce problematic drinking behavior among individuals arrested for the first time for driving under the influence of alcohol (DUI).
- Trial name
- NCT01270217
- Testing
- Brief motivational interview
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of California, Davis
Cigarette Use, Alcohol Use Above Recommended Limits
Developing a Team-Delivered Intervention for Smoking and Hazardous Drinking for Primary Care Veterans With Cardiovascular Diseases
In this study, the investigators are interested in learning how patients feel about and are impacted by a new approach for the primary care team to use to talk to patients about heart disease and health behaviors.
- Conditions
- Cigarette Use, Alcohol Use Above Recommended Limits, Cardiovascular Risk Factors (e.g., Hypertension), Cardiovascular Diseases
- Trial name
- CARE (NCT05275582)
- Testing
- CARE
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Driving Impaired
Validation of Alcohol Level Identification Using DRIVESC
This pilot study will evaluate the feasibility and acceptability of using a commercially available DRIVESC fitness-to-drive measurement tool to detect alcohol-induced impairment in healthy adult participants.
- Trial name
- NCT07282405
- Testing
- DRIVESC, Alcohol
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Alcohol Consumption
Accountability Support Through Peer-Inspired Relationships and Engagement (ASPIRE) Trial
This project aims to test the efficacy of a text message intervention, ASPIRE, designed to address cognitive and behavioral elements and modify exposure to peers that influence drinking behaviors.
- Trial name
- ASPIRE (NCT06617702)
- Testing
- A text message alcohol intervention focused on cognitive, behavioral, and peer influences, A text message alcohol intervention focused on cognitive and behavioral influences
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Stanford University
Multiple Sclerosis
Effect of Interferon Beta-1a (Avonex®) on Changes of Non-conventional MRI Measures in Patients With MS
Phase IV open label, single-blind study, post-marketing, 1-year MRI observational study evaluating effect of Avonex® monotherapy (6.0 MIU administered i.m.
- Trial name
- NCT00463710
- Testing
- Avonex® monotherapy (6.0 MIU administered i.m. each week)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- State University of New York at Buffalo
Alcohol Drinking, Alcohol Intoxication
WayToServePlus: Improving Responsible Alcohol Service Ph II
Responsible beverage service (RBS) training for alcohol servers is a promising intervention for reducing driving while intoxicated (DWI) by alcohol.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Use, Unspecified
- Trial name
- NCT05779774
- Testing
- WayToServe Plus In-service Component, WayToServe Training Only
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Gaming Disorder, Internet Gaming Disorder
Psychological Therapy for Gaming Disorder
Gaming is a common leisure activity, both for children and adult, and while it is generally a positive experience for most, it can lead to problems for some individuals.
- Trial name
- NCT06018922
- Testing
- Psychological treatment
- Where
- Sweden
- Volunteers
- 68 people
- Sponsor
- Region Skane
Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil
Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans
Alcohol is abused commonly, but there is no remedy for alcohol intoxication. This project is looking at the substance iomazenil and its effect on alcohol intoxication and alcohol's effects on driving using a driving simulator.
- Conditions
- Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil, Placebo Ethanol and Active Iomazenil, Placebo Ethanol and Placebo Iomazenil
- Trial name
- NCT01590277
- Testing
- Active Ethanol, Active Iomazenil
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alcohol Abuse, Alcohol Dependence
The iHealth Study in College Students
The objective of this project was to test the feasibility of electronic mail recruitment and web screening for hazardous drinking, to compare different approaches to encouraging screening, and to estimate the effects of minimal…
- Conditions
- Alcohol Abuse, Alcohol Dependence, Unhealthy Alcohol Use, Risky Alcohol Consumption Amounts
- Trial name
- NCT00183131
- Testing
- Brief Personalized Feedback
- Where
- United States
- Volunteers
- 4,300 people
- Sponsor
- Boston Medical Center