Clinical trials: Harmful Use
Drug Use, Harmful Use
BiNational Quit Using Drugs Intervention Trial
The goal of the US-Mexico Binational Quit Using Drugs Intervention Trial (QUIT) is a multi-site study conducted in the US (East Los Angeles) and Mexico (Tijuana) which aims to reduce drug demand on both sides of the border.
- Trial name
- BiN-QUIT (NCT01942811)
- Testing
- Quit Using Drugs Intervention Trial
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Game Plan for PrEP
This small pilot randomized controlled trial will test whether a brief, web-based intervention inspired by the principles of motivational interviewing helps high-risk men who take pre-exposure prophylaxis (PrEP) moderate their…
- Trial name
- NCT04973267
- Testing
- Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Brown University
Use; Tobacco, Harmful, Alcohol Abuse
Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use
The purpose of the project is to improve adolescent behavioral counseling services in healthcare settings with a new Internet/Intranet-based Motivational Enhancement Therapy (iMET) intervention that targets the use of tobacco…
- Conditions
- Use; Tobacco, Harmful, Alcohol Abuse, Drug Abuse
- Trial name
- NCT00907309
- Testing
- iMET, iMET/TE
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Boston Children's Hospital
Alcohol Drinking, Alcohol Intoxication
Family Based Prevention of Alcohol and Risky Sex for Older Teens
An online, interactive web-based program for older teens and their parents is designed to address teen alcohol use and teen relationships.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders
- Trial name
- NCT03521115
- Testing
- Smart Choices 4 Teens
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Chronic Pain, Unhealthy Alcohol Use
Integrated Digital Health Approach to Reduce Hazardous Alcohol Use and Chronic Pain Among Rural Populations
The current proposal seeks to test the benefit of a brief intervention combined with a digital program delivered though a smartphone app for reducing chronic pain and hazardous drinking among those in rural settings.
- Trial name
- NCT07804914
- Testing
- Mobile Intervention for Alcohol and Pain, Control Intervention
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Boston University Charles River Campus
Alcohol Drinking, Alcohol Use Disorder
Understanding Alcohol Reward in Social Context
In this study, the investigators examine whether emotional and social reward from alcohol varies depending on the social context of consumption.
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use
- Trial name
- NCT03449095
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Metabolic Disturbance, Alcohol; Harmful Use
Metabolic Effects of One-weak Heavy Drinking
Examination of the effect of one week's unhealthy lifestyle on glucose metabolism and liver parameters in a group of young, healthy males participating in Roskilde Festival 2016.
- Conditions
- Metabolic Disturbance, Alcohol; Harmful Use, Glucose Intolerance
- Trial name
- ROSMET (NCT04229550)
- Testing
- Festival participation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Alcohol Drinking, Alcohol Use Disorder
Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study
In this study, the investigators aim to capture inter- and intra-brain mechanisms underlying alcohol reward in novel social context.
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use
- Trial name
- NCT06687525
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Hazardous Drinking, Harmful Alcohol Use
Telephone-Based Acceptance and Commitment Therapy for Young Adult Hazardous Drinkers
The goal of this clinical trial is to learn if telephone-based Acceptance and Commitment Therapy (ACT) works to help young adults with hazardous or harmful alcohol use quit drinking.
- Trial name
- NCT07621822
- Testing
- Telephone-Based Acceptance and Commitment Therapy (ACT), Waitlist control with Telephone-Based Social Support
- Volunteers
- 288 people
- Sponsor
- The Hong Kong Polytechnic University
Health Knowledge, Attitudes, Practice, Alcohol Drinking
An Electronic Brief Alcohol Intervention for Women Attending a Breast Screening Service (Health4Her)
Alcohol is a major modifiable risk factor for female breast cancer; yet, awareness of this risk remains surprisingly low and is not systematically addressed in healthcare settings.
- Trial name
- NCT06019442
- Testing
- Brief alcohol intervention (Health4Her-Automated), Lifestyle health promotion
- Where
- Australia
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Turning Point
Addiction, Opioid Dependence
Exploratory Dose Ranging Study Assessing APH-1501 for the Treatment of Opioid Addiction
The purpose of this study is determine the safety, efficacy and tolerability of a novel drug APH-1501 as a pharmacotherapy for Opioid Dependence. The investigators will evaluate the safety of escalating doses APH-1501.
- Conditions
- Addiction, Opioid Dependence, Opioid Withdrawal
- Trial name
- NCT03813095
- Testing
- APH-1501
- Volunteers
- 32 people
- Sponsor
- Aphios
Effectiveness of Screening and Brief-Intervention, Unhealthy Alcohol Use
Screening and Brief-Intervention of Post-war Alcohol Consumption in Public Hospital Outpatients
Background: High prevalence of alcohol-consumption among conflict-affected population has been reported in some low-and-middle income countries.
- Trial name
- NCT06918106
- Testing
- Simple advice, Brief-counseling and brochure
- Where
- Ethiopia
- Volunteers
- 262 people
- Sponsor
- Aksum University
Mental and Behavioral Disorders Due to Harmful Drug Use
HealthCall:Brief Intervention to Reduce Non-injecting Drug Use in HIV Primary Care Clinics
Among HIV-infected individuals, non-injection drug use (NIDU) is associated with poor HIV medication adherence, greater HIV/AIDS risk behaviors, and increasing non-AIDS mortality.
- Trial name
- NCT01312181
- Testing
- HealthCall and Motivational Interviewing, Motivational Interviewing (MI), HIV/AIDS health education
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Cannabis Dependence, Harmful Use
Cannabis Abstinence and Neurocognitive Assessment in Adolescence
Cannabis Abstinence and Neurocognitive Assessment in Adolescence
- Conditions
- Cannabis Dependence, Harmful Use, Cognitive Assessment
- Trial name
- CANAA (NCT07160153)
- Testing
- Neurocognitive assessment, Urine toxicological assessment
- Where
- Czechia
- Volunteers
- 29 people
- Sponsor
- University Hospital Pilsen
Alcohol; Harmful Use, Tobacco Use
Screening While You Wait 2: Alcohol and Tobacco Use
This project aims to help patients improve their health through screening and treatment of risky alcohol and tobacco use. Previous studies show the best approach to reduce substance use includes routine screening, short…
- Conditions
- Alcohol; Harmful Use, Tobacco Use, Tobacco Use Cessation, Alcohol Use, Unspecified
- Trial name
- SWYW2 (NCT04594304)
- Testing
- Behavioral: Usual care plus eToolkit
- Where
- Canada
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Alcohol Use Disorders
The Effect of a Interdisciplinary Alcohol Cessation Intervention
The effect of alcohol interventions seems to be related to the intensity of the interventions. In this study the investigators will assess the effect of a interdisciplinary "booster session" in primary care, given to patients who…
- Trial name
- NCT01208571
- Testing
- "Booster session"
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Helse Stavanger HF
Alcohol Use Disorder (AUD)
Brief Intervention and Fibroscan for Harmful Drinkers Presenting to the Emergency Department
The investigators plan to assess the feasibility of a randomised controlled trial of an innovative screening (Identification), Brief Intervention, Fibroscan and Self-Referral for Specialist Treatment (IBAFiRST) programme for high…
- Trial name
- IBAFiRST (NCT05720247)
- Testing
- Fibroscan, Brief Intervention
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Opioid Use, Opioids; Harmful Use
Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy
Chronic pain management is complex, with healthcare providers historically relying on prescribing opioid medications such as morphine.
- Conditions
- Opioid Use, Opioids; Harmful Use, Hyperalgesia, Pain, Chronic
- Trial name
- NCT04902547
- Testing
- Patient Education Workshop (PEWs), Multidisciplinary Tapering Program
- Where
- 4 sites in Canada
- Volunteers
- 26 people
- Sponsor
- University of Manitoba
Cannabis Use
Reducing the Harmful Effects of Cannabis Use: Finding the Optimal CBD:THC Ratio
This study will recruit healthy volunteers who use cannabis infrequently. Each participant will attend the laboratory on five occasions: an initial visit to check that they are safe to join the study and four days of testing.
- Trial name
- eCBD (NCT05170217)
- Testing
- THC, Cannabidiol
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- King's College London
Alcohol Abuse, Alcohol Dependence
Anonymous Treatment on the Internet for Alcohol Dependence: A Randomised, Controlled Trial
Internet based self help program with or without support of a counselor is tested among anonymous Internet help seekers at an open access website.
- Conditions
- Alcohol Abuse, Alcohol Dependence, Harmful Alcohol Use, Alcohol Use Disorder
- Trial name
- NCT02377726
- Testing
- Alkoholhjälpen counselor support, eChange Alkoholhjälpen, Alkoholhjälpen
- Where
- Sweden
- Volunteers
- 1,170 people
- Sponsor
- Karolinska Institutet