Clinical trials: Hand Function Impairment
Stroke, Hand Functions
Bifocal Transcranial Alternating Current Stimulation Targeting the Frontoparietal Network in Stroke Patients
Hand and arm function is often significantly impaired in stroke patients, making its recovery a primary goal in rehabilitative treatment.
- Conditions
- Stroke, Hand Functions, Cerebrovascular Disease, Brain Diseases
- Trial name
- NCT06809959
- Testing
- In-phase-tACS, Out-of-phase-tACS
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stroke
Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in Post-Stroke Rehabilitation
This randomized clinical trial will examine upper limb rehabilitation in individuals recovering from stroke. The study will compare unilateral and bilateral task-oriented training approaches to determine their relative…
- Trial name
- NCT07523503
- Testing
- Unilateral task oriented training (UTOT) with baseline EMS, Bilateral task oriented training (BTOT) with baseline EMS
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- University of Faisalabad
Stroke, Cerebro-vascular Accident
Combined Effects of Soft Robotic Hand and Electrical Stimulation on Hand Function in Stroke Survivors
Stroke is a clinically delineated syndrome, which is characterised by an acute, focal neurological deficit resulting from vascular injury (infarction or haemorrhage) within the central nervous system.
- Trial name
- NCT07282938
- Testing
- Soft Robotic Hand combined with Neuromuscular Electrical Stimulation along with Task Oriented Training, Neuromuscular Electrical Stimulation along with Task Oriented Training
- Where
- 2 sites in Pakistan
- Volunteers
- 64 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Mild Cognitive Impairment (MCI), Geriatric
Investigation of Different Rehabilitation Approaches in Older Adults With Mild Cognitive Impairment
This randomized controlled trial aims to comparatively examine whether cognitive training and hand exercise training provided to older adults with mild cognitive impairment (MCI) have an impact on their cognitive functions, hand…
- Trial name
- NCT06837493
- Testing
- Resistance based hand exercises and functional task-oriented hand exercise, Cognitive training
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Uşak University
Age-Related Balance Impairment, Healthy Older Adults
Effects of Dynamic Neuromuscular Stabilization Exercises Versus Balance Exercises in Older Adults
The aim of this study is to compare the effects of Dynamic Neuromuscular Stabilization (DNS) based exercises and balance exercises on functional capacity, balance, muscle strength, and quality of life in older adults.
- Trial name
- NCT07495280
- Testing
- Dynamic Neuromuscular Stabilization Exercises, Balance Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Virtual Reality, Coordination Impairment
Effects of Immersive Virtual Reality Traning on an Eye-hand Coordination and Time Reaction
Virtual reality (VR) is a three-dimensional image, which is created by means of computer programs. In most educational communities VR has been used as an opportunity to support many students.
- Trial name
- NCT04662983
- Testing
- VR-training
- Where
- Poland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Healthy Elderly, Mild Cognitive Impairment (MCI)
Hand Training Device For Cognitive Care
Previous studies indicated that auditory stimulation as an external cue might have positive impacts on sensorimotor synchronization.
- Trial name
- NCT06417034
- Testing
- Game Software
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Systemic Sclerosis
Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME)
Almost 90% of systemic sclerosis (SSc) patients experience hand function limitation, which leads to impaired daily functioning and work participation.
- Trial name
- NCT06133244
- Testing
- Imaging, blood samples, fuctional tests and physical examination
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- UMC Utrecht
Stroke, Hemiplegia
Combined Mirror Therapy and Soft Robotic Glove for Hand Recovery After Stroke
Post-stroke hemiplegia frequently results in impaired upper limb function, which significantly affects independence and quality of life.
- Conditions
- Stroke, Hemiplegia, Upper Limb Motor Impairment
- Trial name
- MT-SRG (NCT07467915)
- Testing
- Conventional Rehabilitation, Mirror Therapy, Soft Robotic Glove
- Where
- Iraq
- Volunteers
- 104 people
- Sponsor
- University of Baghdad
Stroke, Stroke, Ischemic
Efficacy of REMO Training for Hand Motor Recovery After Stroke
Upper limb motor impairment is one of the most common sequelae after stroke. Indeed, the recovery of upper limb sensory-motor functions remains one of the most important goals in stroke rehabilitation.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke Sequelae
- Trial name
- REMO (NCT05815368)
- Testing
- REMO, Task-Oriented Training
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Parkinson Disease
Robotic Assessments of Hand Function in Patients With Parkinson's Disease
It has been shown that patients with Parkinson's disease (PD) have impaired kinaesthesia and haptic perception of the upper limbs.
- Trial name
- RHK Parkinson (NCT05245955)
- Testing
- Assessments of the hand sensory function with the ReHapticKnob
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Upper Limb Dysfunction, Hand Function Impairment
3D-Printed Mobile Phone Holder for Individuals With Upper Limb Impairments
Individuals with upper limb functional impairments, such as those resulting from stroke, spinal cord injury, musculoskeletal disorders, or degenerative joint disease, often experience difficulties operating smartphones.
- Conditions
- Upper Limb Dysfunction, Hand Function Impairment, Musculoskeletal Disorders Affecting Hand Function, Difficulty Operating Smartphones Due to Upper Limb Impairment
- Trial name
- NCT07561944
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Stroke, Impaired Upper Extremity Function
Extension of the MIME Robotic System for Stroke Rehabilitation
The goal of this project is to develop and test a new robotic system to accommodate practice of tasks requiring reach, grasp and release of objects.
- Trial name
- NCT00995774
- Testing
- robotic therapy, conventional functional training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- US Department of Veterans Affairs
Breast Cancer, FIT-HaNSA
The Validity and Reliability of FIT-HaNSA in Breast Cancer Patients
Breast cancer is the most common type of cancer among women and covers 25% of all cancers. After mastectomy and reconstruction, many patients develop various upper extremity complications such as joint movement limitation, pain…
- Conditions
- Breast Cancer, FIT-HaNSA, Upper Extremity Dysfunction
- Trial name
- NCT04795778
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Mild Cognitive Impairment (MCI)
VR Hand Exercises: Impact on Cognition and Dexterity in MCI
This study aims to investigate the effects of virtual reality (VR)-based hand exercises on cognitive functions and hand skills in older adults with mild cognitive impairment (MCI).
- Trial name
- NCT07005271
- Testing
- virtual reality, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Istinye University
HIV Associated Neurocognitive Disorder
Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder
The purpose of this study is to see if paroxetine and fluconazole are safe and effective as a treatment for problems with memory, concentration, thinking, and judgment in people who are infected with HIV.
- Trial name
- ParaFlu (NCT01354314)
- Testing
- Fluconazole, Paroxetine, Paroxetine and Fluconazole
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Johns Hopkins University
Assessment of Arm and Hand Sensorimotor Functions in Multiple Sclerosis Subjects
Validation of a Novel Instrument Task for Assessing Upper Limb
The aim of this study i to investigate a new approach (Physical Peg Insertion Test, PPIT) to measure sensorimotor function in the arm and hand.
- Trial name
- NCT04868370
- Testing
- Assessment of the upper limb (VPIT + PPIT)
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Alzheimer's Disease, MCI Due to AD
Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease
The goal of this observational cross-sectional study is to explore the characteristics of language, speech, and motor function in persons with Mild Cognitive Impairment due to Alzheimer's disease ("MCI due to AD") and persons…
- Conditions
- Alzheimer's Disease, MCI Due to AD, Dementia Alzheimers
- Trial name
- NCT06508268
- Testing
- GAITRite walkway system OR 4-meter walking speed test, Jamar hand dynamometer, Picture description task
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Stroke Rehabilitation
Digital Interactive Technologies in Rehabilitation of Post-sroke Patients With Impaired Fine Function of the Hand
The aim of the study is to investigate the efficacy and safety of digital interactive technology with artificial intelligence and biofeedback Smart glove "SensoRehab" for restoration of in-hand manipulation in patients with…
- Trial name
- NCT05214521
- Testing
- digital interactive technology Smart glove "SensoRehab"
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Stroke, Spinal Cord Injuries
Improving Grasp Function in People With Sensorimotor Impairments by Combining Electrical Stimulation With a Robotic Hand Orthosis
Hand motor and sensory impairments resulting from neurological disorders or injuries affect more than 50 million individuals worldwide.
- Conditions
- Stroke, Spinal Cord Injuries, Traumatic Brain Injury
- Trial name
- SENSIBLE-EXO (NCT05976087)
- Testing
- SensoExo
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Andrea Cimolato