Clinical trials: Halitosis
Periodontitis, Olfactory Dysfunction
Olfactory Function and Oral Malodor in Periodontitis Before and After Periodontal Therapy
This prospective cohort study investigated the relationship between oral malodor and olfactory function in adults with generalized periodontitis.
- Conditions
- Periodontitis, Olfactory Dysfunction, Halitosis
- Trial name
- NCT07424300
- Testing
- Scaling and Root Planing (SRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Batman University
Periodontal Diseases, Oral Halitosis
The Effect of Regular Home Use of Dual-light Antibacterial Photodynamic Therapy (aPDT) or the Use of a Powered Toothbrush in Older Individuals With Periodontitis and Mild Cognitive Impairment.
Objective: To compare three different oral hygiene regimens regarding plaque index (PI), bleeding on probing (BOP), the number of deepened periodontal pockets ≥4 mm (PPD), oral halitosis, and changes in oral health-related…
- Trial name
- e-DENT II (NCT07166224)
- Testing
- Oral-B Powered toothbrush, Dual-Light aPDT Treatment - Lumoral
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Blekinge Institute of Technology
Halitosis, Periodontal Health
Effects of Green Tea Mouthwash on Halitosis, Periodontal Health, and Stress in Orthodontic Patients
This randomized, double-blind, four-arm clinical trial evaluates the effects of green tea mouthwash on halitosis, periodontal health, salivary stress biomarkers, and oxidative stress in patients undergoing fixed orthodontic…
- Conditions
- Halitosis, Periodontal Health, Orthodontic Treatment
- Trial name
- NCT07829224
- Testing
- Green Tea Mouthwash A, Green Tea Mouthwash B, Fluoride Mouthwash
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Universiti Sains Malaysia
Healthy, Halitosis
Effectiveness of Aquamin® in Mitigating Halitosis
The purpose of this study is to assess whether Aquamin®, a multi-mineral natural product from red marine algae, can help reduce halitosis when taken for 90 days.
- Trial name
- NCT05058638
- Testing
- Aquamin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Oral Malodor (Halitosis), Oral Dryness
Effects of a 50+ Toothpaste on Halitosis and Oral Comfort in Healthy Adults
The goal of this clinical trial is to compare a toothpaste designed for adults aged 50 years and older with a standard toothpaste in orally healthy adults.
- Trial name
- HALI-50PLUS (NCT07780474)
- Testing
- 50+ Toothpaste, Standard Fluoride Toothpaste
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Gingivitis, Halitosis
Evaluation of the Safety and Efficacy of SALI-10 Probiotic Lozenges
Gingivitis is among the most common oral conditions, affecting 50-90% of adults globally. It is a reversible inflammatory disease triggered primarily by the accumulation of microbial plaque on teeth and gingival tissues.
- Trial name
- NCT07508839
- Testing
- 3B SALI-10 Lozenge
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ostia Sciences
Halitosis
Evaluation of the Stability of Sulfur Volatile Compounds From Exhaled Air for Halitosis Diagnosis
Halitosis or bad breath is a problem affecting 30% of the world's population. There are many causes, and oral pathologies, including periodontitis, are the main etiology.
- Trial name
- HALITOSIX (NCT06483646)
- Testing
- Gaseous sampling:
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Halitosis, Dentistry
Effect of Dental Education Duration on Halitosis and Associated Factors
The study population will consist of undergraduate dental students enrolled at Recep Tayyip Erdoğan University Faculty of Dentistry.
- Trial name
- NCT07740876
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Gastrointestinal Symptoms, Bloating
A Clinical Trial to Evaluate the Effects of Super Liver Liquid Drops on Gut Health, Digestive Comfort, and Daily Energy Levels
This is a decentralized (fully virtual), single-group, open-label, prospective clinical trial evaluating the effects of Super Liver Liquid Drops, a liquid botanical dietary supplement, on gut health, digestive comfort, energy…
- Conditions
- Gastrointestinal Symptoms, Bloating, Digestive Discomfort, Low Energy Levels
- Trial name
- NCT07742657
- Testing
- Super Liver
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- SuperBonsai Inc.
Bronchiectasis, Periodontal Disease
Evaluation of Periodontal Treatment in Patients With Bronchiectasis
Background: Association between periodontal disease (PD) and chronic obstructive pulmonary disease (COPD) has been widely studied and the aspiration of periodontal pathogens is one of the most accepted causal mechanisms for…
- Trial name
- NCT02514226
- Testing
- supragingival treatment, periodontal treatment, periodontal treatment and photodynamic therapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Plaque-Induced Gingivitis, Dental Plaque Accumulation
Innovative Mouthwash in School-Aged Children With Fixed Orthodontic Appliances
Fixed metal orthodontic appliances create additional plaque-retentive areas around brackets, archwires and ligatures, making mechanical plaque control more difficult in children and adolescents.
- Conditions
- Plaque-Induced Gingivitis, Dental Plaque Accumulation, Halitosis
- Trial name
- NCT07710144
- Testing
- Test mouthwash, Chlorhexidine-containing mouthwash
- Where
- Bulgaria
- Volunteers
- 90 people
- Sponsor
- Plovdiv Medical University
Bad Breath, Tooth Sensitivity
A Clinical Trial to Evaluate the Effects of Larineco Remineralizing Gum on Oral Health, Breath Freshness, Tooth Sensitivity, and Gum Comfort
This is a single-group, open-label, decentralized (virtual) clinical trial evaluating the effects of Larineco Remineralizing Gum on self-reported oral health outcomes in 40 generally healthy adults aged 18-57 years who experience…
- Trial name
- NCT07692581
- Testing
- Larineco Remineralizing Gum
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Larine C Corporation
Halitoses
Probiotic Vs Zinc Chlorhexidine Zn/CHX Mouthwashes in Control Halitosis and Plaque in Fixed Orthodontic Patients
This study aims to determine the effect of probiotics and Zn/CHx mouthwashes on plaque accumulation and halitosis in fixed orthodontic patients.
- Trial name
- NCT07693972
- Testing
- Probiotic (L. brevis CD2 lozenges), Zinc chlorhexidine mouth wash
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sara M Almshhadany
Halitosis, Periodontal Diseases
Tedlar Bag Stability of Volatile Sulfur Compounds for Remote Halitosis Diagnosis
Halitosis, or bad breath, affects about 30% of people worldwide and is most often caused by oral diseases such as periodontitis.
- Trial name
- Malodorix (NCT07602309)
- Testing
- Breath sample collection with Tedlar bags PLV 0.6L and plastic syringe 1cc
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Kidney Disease
Oral and Dental Health Status in Patients Suffering From Chronic Kidney Disease
A large panel of oral and dental diseases exist in patients suffering from chronic kidney disease (CKD) in end-stage renal disease: it concerns teeth, peridontium, alveolar bone and saliva and it has been already described in the…
- Trial name
- NEPHRODENT (NCT02114281)
- Testing
- Care, Not care
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Bordeaux
Type 2 Diabetes, Halitosis
Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus
The goal of this clinical trial is to evaluate the effectiveness of periodontal treatment associated with the use of a tongue scraper, compared with the same treatment combined with antimicrobial photodynamic therapy (aPDT), in…
- Conditions
- Type 2 Diabetes, Halitosis, Periodontitis
- Trial name
- NCT07463859
- Testing
- Scaling and root planing, Photodynamic Therapy with Conventional Methylene Blue
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo
Denture Stomatitis, Dentures
Oral Probiotics and Denture Care in Saudi Arabia: Evaluating Knowledge, Practices, and the Future of Innovative Hygiene Solutions
The goal of this observational study is to learn about denture wearers' knowledge, awareness, and self-reported practices regarding denture hygiene and oral probiotics, and to assess whether these are associated with clinical…
- Conditions
- Denture Stomatitis, Dentures, Halitosis, Biofilms
- Trial name
- NCT07475195
- Testing
- This is a cross-sectional observational study. Participants are not assigned to any treatment or preventive intervention.
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Saud University
Xerostomia, Halitosis
Effect of Whitening Agent With Emulsion Gel in Saliva and Halitosis
The objective of this study is to evaluate how well the study product, Crest Daily Whitening Serum, alleviates Xerostomia and perceived halitosis over 1 week of use.
- Trial name
- NCT06194123
- Testing
- Crest Daily Whitening Serum
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Tufts University
Halitosis, Halitoses
Antimicrobial Photodynamic Therapy Or Lingual Scraper Associated With Periodontal Treatment In The Reduction Of Halitosis.
The aim of this study is to compare the effectiveness of two methods of treating bad breath. Patients are enrolled in the study based on an objective test using the Oral Chroma Device, which measures the concentration of volatile…
- Conditions
- Halitosis, Halitoses, Fetor Oris, Oral Malodor
- Trial name
- NCT07433816
- Testing
- Tongue scraper and oral rinse treatment, Tongue scraper and aPDT (photodynamic therapy), full mouth scaling
- Where
- Poland
- Volunteers
- 48 people
- Sponsor
- Medical University of Silesia
Oral Malodor (Halitosis)
Evaluation of a Stannous Fluoride Dentifrice for Control of Oral Malodor
This single-center, randomized, double-blind, two-treatment crossover clinical study evaluated the safety and efficacy of a stannous fluoride-containing dentifrice compared with a sodium fluoride control dentifrice for the…
- Trial name
- NCT07425509
- Testing
- Sodium Fluoride Dentifrice, Stannous Fluoride Toothpaste (SnF)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.