Clinical trials: HMSN
Carpal Tunnel Syndrome (CTS)
Ultrasound-Guided Percutaneous Release vs. Open Surgery for Carpal Tunnel Syndrome
The goal of this clinical trial is to compare the clinical and functional outcomes of two surgical approaches for the treatment of carpal tunnel syndrome (CTS): ultrasound-guided percutaneous release of the flexor retinaculum and…
- Trial name
- NCT07230782
- Testing
- Percutaneous Ultrasound Guided Release of the Transverse Carpal Ligament, Open release surgery
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Carpal Tunnel Syndrome
Amniotic Membrane in Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is the most frequent mononeuropathy. CTS is more frequent in females than in males, it has been associated to work activities, hormone exposure and obesity.
- Trial name
- NCT04075357
- Testing
- Amniotic membrane transplantation
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Thoracic Outlet Syndrome
Treatment of Thoracic Outlet Syndrome (TOS) With Botox
The purpose of this study is: 1. To assess the effect of BOTOX injection to the scalene muscles on the severity of pain from TOS. 2. To assess the effect of BOTOX injection on numbness and tingling and quality of life.
- Trial name
- NCT00444886
- Testing
- Botulinum Toxin Type A injection (BOTOX)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Cubital Tunnel Syndrome
Mechanical Interference Versus Neural Mobilization on Ulnar Neuropathy Post Cubital Tunnel Syndrome
this study will be conducted to compare between mechanical interference and neural mobilization on ulnar neuropathy post-cubital tunnel syndrome
- Trial name
- CTS (NCT05931731)
- Testing
- Mechanical interference, Neural mobilization, conventional treatment
- Volunteers
- 90 people
- Sponsor
- Cairo University
Nerve Compression Syndromes
Erythropoietin Spinal Cord Compression Randomized Trial
To determine whether erythropoietin, steroids and radiotherapy is safe and feasible to administer to patients with malignant spinal cord compression.
- Trial name
- NCT00220675
- Testing
- Erythropoietin infusion
- Where
- 3 sites in Canada
- Volunteers
- 7 people
- Sponsor
- Sunnybrook Health Sciences Centre
Carpal Tunnel Syndrome
Steroid Injection Treatment of Carpal Tunnel Syndrome
The aim of this study is to assess the efficacy of injecting steroid into the carpal tunnel in relieving symptoms of carpal tunnel syndrome for at least 1 year with outcomes measured with patient evaluated symptoms score.Out of…
- Trial name
- NCT00806871
- Testing
- Methylprednisolone 40 mg, Methylprednisolone 80 mg, Sodium chloride
- Where
- Sweden
- Volunteers
- 112 people
- Sponsor
- Region Skane
Head and Neck Cancer, Neck Dissection
Porcine Extracellular Matrix Nerve Wrap in Neck Dissection for Head and Neck Cancer
Perform a preliminary efficacy study using the porcine extracellular matrix nerve wrap (AxoGuard Nerve Protector™, AxoGen Inc., Alachua, FL) to wrap the spinal accessory nerve (SAN) during neck dissections for head and neck…
- Conditions
- Head and Neck Cancer, Neck Dissection, Postoperative Complications
- Trial name
- NCT07268092
- Testing
- Porcine Extracellular Matrix Nerve Wrap (AxoGuard Nerve Protector™)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Henry Ford Health System
Transthyretin Amyloidosis, Carpal Tunnel Syndrome
Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release Surgery
This study will determine the prevalence of transthyretin amyloidosis in pathology of the transverse carpal ligament and cardiac involvement using natriuretic peptides, electrocardiography and echocardiography in patients…
- Trial name
- PRATHYC (NCT04611204)
- Testing
- Descriptive cohort
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Toulouse
Pelvic Pain Syndrome, Sacroiliac Disorder
Chronic Pelvic Pain in Females and Males
Pelvic pain is under-reported in healthy adults. Many patients with pelvic pain under-estimate the problem. Chronic pelvic pain can be managed properly, if diagnosed promptly.
- Conditions
- Pelvic Pain Syndrome, Sacroiliac Disorder, Piriformis Syndrome, Sacrococcygeal Disorder
- Trial name
- NCT06102733
- Testing
- Rehabilitation therapy
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Carpal Tunnel Syndrome
Comparison of the Efficacy of Peloid Therapy and Paraffin Treatment in Carpal Tunnel Syndrome
This study compares the effectiveness of peloid therapy and paraffin treatment in carpal tunnel syndrome. Patients who have already received 2 weeks of peloid therapy or 15 sessions of paraffin treatment will be assessed.
- Trial name
- NCT06405438
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Beylikduzu State Hospital
Carpal Tunnel Syndrome
WALANT Versus Local Anesthesia With Tourniquet for Carpal Tunnel Decompression
This multicenter, randomized, double-blinded controlled trial compared two local anesthetic techniques for open carpal tunnel decompression in adults.
- Trial name
- WALANT vs LA-T (NCT07617064)
- Testing
- WALANT technique for carpal tunnel decompression, Local anesthesia with tourniquet for carpal tunnel decompression
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Misr University for Science and Technology
Cubital Tunnel Syndrome, Peroneal Nerve Entrapment
Mechanomyography for Predictor of Prognosis in CuTS and PND Patients
The study will be a non-blinded two cohort design consisting only of symptomatic patients with CuTS or compressive peroneal neuropathy or in need of peroneal nerve decompression. The first cohort will be - patients with CuTS.
- Trial name
- NCT04322448
- Testing
- Mechanomyography (MMG)
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Washington University School of Medicine
Carpal Tunnel Syndrome
Predictive Value of Baseline CTQ-SSS Scores for Progression to Carpal Tunnel Release Surgery: A Cohort Study
This study aims to determine the predictive value of baseline CTQ-SSS scores for progression to carpal tunnel release (CTR) surgery in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT05838963
- Testing
- CTQ-SSS scores
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ahram Canadian University
Carpal Tunnel Syndrome
The Effectiveness of Physical Therapy Modalities in Carpal Tunnel Syndrome
Carpal tunnel syndrome is considered to be the most common entrapment neuropathy. Conservative treatment is recommended in the mild and moderate stage of CTS.
- Trial name
- NCT03061149
- Testing
- Low-level laser therapy, Ultrasound treatment
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Poznan University of Medical Sciences
Carpal Tunnel Syndrome
BOTOX® (Onabotulinumtoxin A) Injection(s) as a Treatment for Carpal Tunnel Syndrome
This study will be a prospective double blind controlled randomized trial of ten patients diagnosed with Carpal Tunnel Syndrome (CTS). The study will be completed at offices of medical practices in Arizona.
- Trial name
- NCT02070302
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Benjamin Sucher
Hereditary Spastic Paraparesis
Testing Miglustat Administration in Subjects With Spastic Paraplegia 11
Hereditary spastic paraparesis type 11 (SPG11) is caused by mutations in the SPG11 gene that produces spatacsin, a protein involved in lysosomal function.
- Trial name
- TreatSPG11 (NCT04768166)
- Testing
- Miglustat 100 MG
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- IRCCS Fondazione Stella Maris
Carpal Tunnel Syndrome
Effects of Platelet-rich Plasma in the Surgery of Carpal Tunnel Syndrome: A Randomized Controlled Trial
The Platelet-rich plasma (PRP) has been proved to be efficient in the non-surgical treatment of carpal tunnel syndrome (CTS). Here we propose to assess the effectiveness of PRP as co-adjuvant in surgical treatment of CTS by open…
- Trial name
- PRP-CTS (NCT03548259)
- Testing
- Platelet-rich plasma, Platelet-poor plasma
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cardenal Herrera University
Carpal Tunnel Syndrome
Safety and Efficacy of a Device for the Relief of Pain Due to Carpal Tunnel Syndrome
Interventional study to evaluate efficacy and safety of an active splint.
- Trial name
- NCT03810326
- Testing
- CTR device (tradename named Xtend)
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yuinvent Innovations Ltd.
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Carpal Tunnel Syndrome
Ultrasound Therapy for Carpal Tunnel Syndrome (CTS)
Carpal Tunnel Syndrome (CTS) is a recognisable pattern of symptoms and signs, which are caused by compression of the median (middle) nerve as it passes through the carpal tunnel at the wrist.
- Trial name
- CTS (NCT01590745)
- Testing
- EMS Therasonic 460 Primo Ultrasound therapy
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust