Clinical trials: HIP AND KNEE OSTEOARTHRITIS
Osteoarthritis
Meloxicam SoluMatrix® Capsules vs Meloxicam Tablets to Treat Osteoarthritis Pain
The purpose of this study is to evaluate the safety and efficacy of a low dose and a high dose of Meloxicam SoluMatrix® Capsules versus Meloxicam Tablets for the treatment of pain due to osteoarthritis of the knee or hip.
- Trial name
- NCT02405793
- Testing
- Meloxicam Test Capsules, Meloxicam Tablets
- Sponsor
- Iroko Pharmaceuticals, LLC
Pain Management, Osteoarthritis
Efficacy and Safety of Etoricoxib+Diacerein in Osteoarthritis.
The goal of this clinical trial is to learn if fixed-dose combination etoricoxib 90 mg + diacerein 50 mg capsule works to treat knee/hip osteoarthritis-associated pain in adults. It will also learn about the safety of the drug.
- Trial name
- NCT07549386
- Testing
- Etoricoxib 90 mg + diacerein 50 mg, Meloxicam 15 mg + diacerein 50 mg
- Where
- 4 sites in Mexico
- Volunteers
- 123 people
- Sponsor
- Laboratorios Liomont
Osteoarthritis
A Study of Pain Relief in Osteoarthritis
The purpose of this study is to compare the safety and pain-relieving ability of Vicodin CR to placebo in subjects with osteoarthritis (OA) of the hip or knee.
- Trial name
- NCT00298974
- Testing
- hydrocodone / acetaminophen extended release
- Where
- 83 sites in United States
- Volunteers
- 873 people
- Sponsor
- Abbott
Joint Pain, Knee Osteoarthritis
Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute Exacerbation
This is a Phase III, longitudinal, multicenter, randomized, double-blind clinical trial designed to evaluate the efficacy and safety of a fixed-dose combination of celecoxib and acetaminophen compared to celecoxib monotherapy for…
- Conditions
- Joint Pain, Knee Osteoarthritis, Hip Osteoarthritis
- Trial name
- PRECEDENT (NCT06863636)
- Testing
- Celecoxib + Acetaminophen, Celecoxib
- Where
- Mexico
- Volunteers
- 231 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Pain
Long-term Safety of PF-00345439 (Oxycodone)
Long-Term Safety Of PF-00345439 (Oxycodone) In Patients With Moderate To Severe Chronic Low Back Pain Or Osteoarthritis
- Trial name
- NCT01559701
- Testing
- PF-00345439
- Volunteers
- 823 people
- Sponsor
- Pain Therapeutics
Osteoarthritis
Prospective Multicenter Non-interventional Study in Patients With Knee or Hip Osteoarthritis Having a Theraflex Treatment
The main purpose of this study is to evaluate how a long-term treatment with Theraflex during 64 weeks affects pain intensity in the affected knee or hip joint, the activity in daily living, the quality of life and patient…
- Trial name
- NCT03330288
- Testing
- Theraflex, BAY 874017
- Where
- 2 sites in Russia
- Volunteers
- 1,102 people
- Sponsor
- Bayer
Osteoarthritis
Extension Study Of Tanezumab In Osteoarthritis
Safety extension study of Phase 3 Osteoarthritis trials with Tanezumab
- Trial name
- NCT00809783
- Testing
- tanezumab
- Where
- 226 sites in United States
- Volunteers
- 2,147 people
- Sponsor
- Pfizer
Joint Osteoarthritis, Knee Osteoarthristis
Clinical Evaluation of TrHCROSS® for Different Joints
This post-market clinical investigation is designed to evaluate the safety and effectiveness of TrHCROSS®, a CE-marked cross-linked hyaluronic acid viscosupplement, in patients with mild to moderate osteoarthritis of the knee…
- Conditions
- Joint Osteoarthritis, Knee Osteoarthristis, Hip Ostearthritis, Shoulder Osteoarthritis
- Trial name
- NCT07870031
- Testing
- TrHCROSS®, Monovisc
- Volunteers
- 150 people
- Sponsor
- i+Med S.Coop.
Osteoarthritis, Knee, Osteoarthritis, Hip
Efficacy and Safety of a Subcutaneous Tanezumab Titration Dosing Regimen in Subjects With Moderate to Severe Osteoarthritis of the Hip or Knee
The primary purpose of this study is to evaluate the efficacy of a titration arm of tanezumab in which treatment is started at a lower dose (2.5 mg) and increased to a higher dose (5 mg) at Week 8, compared to giving 2 doses of…
- Trial name
- NCT02697773
- Testing
- Tanezumab 2.5 mg, Tanezumab 2.5mg/5mg
- Where
- 87 sites in United States, Canada and 1 more
- Volunteers
- 698 people
- Sponsor
- Pfizer
Osteoarthritis
Use of Autologous Adipose-Derived Stromal Vascular Fraction To Treat Osteoarthritis of Hip, Knee, Ankle, and Thumb Joints
This study will examine the safety and efficacy of autologous adipose-derived stromal vascular fraction (SVF) cells for treatment of hip, knee and thumb osteoarthritis (OA); monitoring adverse events and measuring pain, function…
- Trial name
- NCT03166410
- Testing
- Cell injection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Texas Plastic Surgery
Knee Osteoarthritis, Hip Osteoarthritis
The Kaia Hip and Knee Pain Intervention for Self-management of the Pain in Patients With Osteoarthritis.
The study intervention provides an innovative way of making exercise training and other recommended lifestyle modifications as accessible as possible for knee and hip OA participants by introducing a home-based exercise training…
- Trial name
- PIVOT (NCT04615377)
- Testing
- Kaia hip and knee pain application, Treatment as usual
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Kaia Health Software
Health-related Quality of Life, Pain
Outcomes During Digitally Delivered Osteoarthritis Treatment
Objectives: To examine changes in health-related quality of life (HRQL), pain and function among patients with knee or hip osteoarthritis (OA) participating in digitally delivered exercise and education treatment for up to 12 or…
- Conditions
- Health-related Quality of Life, Pain, Function, Osteoarthritis, Knee
- Trial name
- NCT05026580
- Testing
- Joint Academy exercise and education smart phone application
- Where
- Sweden
- Sponsor
- Joint Academy
Osteoarthritis of the Hip or Knee
Dexibuprofen 400 mg Sachet Versus Ibuprofen 400 mg Sachet in Patients With Osteoarthritis of the Hip or Knee
Medical condition under investigation: Osteoarthritis of the hip or knee Number of patients planned: 480 adult patients Main objective: To evaluate and compare the tolerability profile of Dexibuprofen Gebro 400 mg powder for oral…
- Trial name
- NCT01066676
- Testing
- Dexibuprofen, Ibuprofen
- Where
- 2 sites in Austria
- Volunteers
- 482 people
- Sponsor
- Gebro Pharma GmbH
Chronic Pain
A Double-blind Study of Controlled Release OROS Hydromorphone Compared to Placebo in Patients With Chronic Osteoarthritis (OA) Pain
To evaluate the efficacy of OROS Hydromorphone in reducing moderate to severe chronic pain in patients with Osteoarthritis (OA) Pain
- Trial name
- NCT00631319
- Testing
- OROS hydromorphone
- Volunteers
- 343 people
- Sponsor
- Mallinckrodt
Pain, Physical Function
Osteoarthritis Outcomes in Different Ages
We aim to study if there are differences in outcomes between different age groups for persons with knee or hip osteoarthritis during treatment in digitally delivered exercise and education treatment.
- Conditions
- Pain, Physical Function, Age
- Trial name
- NCT05208463
- Testing
- Joint Academy
- Where
- Sweden
- Volunteers
- 14,610 people
- Sponsor
- Joint Academy
Osteoarthritis
Study to Compare Prescription Non-Steroidal Anti-Inflammatory Drug (NSAID) Changes, Health Care Utilization, Efficacy and Safety of Meloxicam 7.5 mg Versus Usual Care Administration of Prescription NSAIDs in a Managed Healthcare Setting in Patients With Osteoarthritis
Study to compare the percentage of treatment successes or failures in patients randomized to meloxicam 7.5 mg vs. usual care prescription NSAIDs.
- Trial name
- NCT02183064
- Testing
- Meloxicam, NSAID
- Volunteers
- 1,309 people
- Sponsor
- Boehringer Ingelheim
Osteoarthritis
Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.
The objective of this study is to assess the safety and efficacy of the buprenorphine transdermal system (5, 10, and 20 mg) in comparison to placebo transdermal system in subjects with osteoarthritis pain.
- Trial name
- NCT00314652
- Testing
- Buprenorphine transdermal delivery system
- Where
- 22 sites in United States
- Volunteers
- 260 people
- Sponsor
- Purdue Pharma LP
Pain, Osteoarthritis
Comparison of BTDS (Buprenorphine Transdermal System) and Placebo in Osteoarthritic Pain
The primary objective of this study is to evaluate the efficacy and safety of BTDS compared to placebo in subjects with moderate to severe osteoarthritic pain of the hip or knee.
- Trial name
- NCT00345787
- Testing
- Buprenorphine Transdermal System
- Where
- 28 sites in Japan
- Volunteers
- 262 people
- Sponsor
- Mundipharma K.K.
Osteoarthritis
Study of Meloxicam Capsules in Subjects With Osteoarthritis of the Knee or Hip
The purpose of this study is to evaluate the safety of Meloxicam SoluMatrix Capsules for up to 52 weeks in subjects with pain due to osteoarthritis (OA) of the knee or hip
- Trial name
- NCT01801735
- Testing
- Meloxicam Test Capsules
- Where
- 40 sites in United States
- Volunteers
- 600 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Osteoarthritis, Hip, Osteoarthritis, Knee
Study of the Analgesic Efficacy and Safety of Subcutaneous Tanezumab in Subjects With Osteoarthritis of the Hip or Knee.
Tanezumab is a monoclonal antibody that binds to and inhibits the actions of nerve growth factor (NGF). The Nerve Growth Factor Inhibitor (NGFI) class may offer an important breakthrough in the treatment of chronic pain and is…
- Trial name
- NCT02709486
- Testing
- Tanezumab
- Where
- 148 sites in Austria, Bulgaria and 13 more
- Volunteers
- 849 people
- Sponsor
- Pfizer