Clinical trials: Gynecologic Surgeries
Postoperative Nausea and Vomiting
Aprepitant for Prevention of Postoperative Nausea and Vomiting in Elective Hysterectomy
The purpose of the study is to determine whether 40 mg aprepitant administered before surgery is effective for preventing vomiting in the first 24 hours after surgery in women undergoing elective hysterectomy.
- Trial name
- NCT00888329
- Testing
- Aprepitant
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Mayo Clinic
Laparoscopic Gynecologic Surgery
Utilizing Telemedicine for Delivery of Postoperative Care
The investigators propose a pilot project in which enrolled patients undergoing major gynecologic surgery will be randomized to either a traditional office postoperative visit or a telemedicine postoperative visit.
- Trial name
- Telemedicine (NCT04348357)
- Testing
- Telemedicine, Office visit
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Postoperative Anaemia
The Use of Iron Therapy for Patients With Anemia After Caesarean Section
The purpose of this study is to determine whether oral or intravenous iron is effective in the treatment of anaemia (iron-poor blood) after caesarean section.
- Trial name
- VITAPOP (NCT01975272)
- Testing
- Ferinject, Ferrous fumarate
- Where
- 2 sites in Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Postoperative Complications, Obesity
Negative Pressure Wound Therapy in Obese Gynecologic Oncology Patients
The purpose of the study is to test whether the use of a new wound closure technique can decrease the rates of wound complications in obese cancer patients.
- Conditions
- Postoperative Complications, Obesity, Gynecologic Neoplasms
- Trial name
- NCT02309944
- Testing
- Standard Wound Closure, Prevena™ Incision Management System
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Neuromuscular Blockade
Optimizing Surgical Conditions During Gynecologic Laparoscopic Surgery With Deep Neuromuscular Blockade
To investigate if deep neuromuscular blockade improves intraabdominal volume compared to no neuromuscular blockade in patients scheduled for gynecologic laparoscopic surgery with pneumoperitoneum 12 mmHg.
- Trial name
- NCT01933425
- Testing
- rocuronium, sugammadex
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Herlev Hospital
Constipation
Prunes for Gastrointestinal Function After Gynecologic Surgery
This is a prospective, randomized control trial that randomizes patients post-operatively into standard care versus standard care plus prunes.
- Trial name
- NCT03523715
- Testing
- Prunes, Docusate Sodium
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of Southern California
Surgery, Anesthesia
Intravenous Sedation Versus General Anesthesia in Patients Undergoing Minor Gynecologic Surgery
The use of deep sedation may improve the quality of recovery of patients undergoing minor gynecologic procedures. These patients may also have shorter hospital stays and potentially lower healthcare costs.
- Conditions
- Surgery, Anesthesia, Pain
- Trial name
- NCT01890707
- Testing
- General Anesthesia, Deep Sedation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Northwestern University
Anaesthesia
Comparison of Laryngeal Mask Airway Supreme and Endotracheal Tube In Patients Undergoing Gynecological Laparoscopy Surgery
Endotracheal Tube (ETT) is still preferred for laparoscopic surgeries because of the fear of pulmonary aspiration and inadequate ventilation.
- Trial name
- NCT02127632
- Testing
- Endotracheal Tube, Laryngeal Mask Airway-Supreme
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dokuz Eylul University
Digestive System Carcinoma, Genitourinary System Carcinoma
Home Base Telemonitoring in Gastrointestinal, Genitourinary, or Gynecologic Cancer Patients Undergoing Abdominal Surgery
This phase III trial compares a home-based telemonitoring program that collects symptom and daily step information to surgeon only care in improving recovery and stopping complications within 30 days after surgery in patients…
- Conditions
- Digestive System Carcinoma, Genitourinary System Carcinoma, Malignant Female Reproductive System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04596384
- Testing
- Best Practice, Functional Assessment, Medical Device Usage and Evaluation
- Where
- 3 sites in United States
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Intrauterine Device Complications, Contraceptive Device Failure
Patient Factors Associated With Fragmentation of Copper Intrauterine Device (IUD) Requiring Hysteroscopic Removal
The purpose of this retrospective chart review was to identify risks factors for patients associated to Cooper IUD fragmentation upon removal resulting in the requirement of a hysteroscopy evaluation.
- Conditions
- Intrauterine Device Complications, Contraceptive Device Failure, IUD Fragmentation, Retained Intrauterine Device
- Trial name
- NCT07351084
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Kansas Medical Center
Anaesthesia
Laryngeal Mask Supreme During Laparoscopic Gynecologic Surgery
Laryngeal mask (LM) use in gynecological laparoscopy, contrary to widespread opinion, does not increase the incidence of gastric aspiration, the failure of ventilation or the risk of pulmonary aspiration .
- Trial name
- NCT02125838
- Testing
- Laryngeal Mask Airway-Supreme, Endotracheal Tube
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Dokuz Eylul University
Intraocular Pressure, Oncology
Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients
Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in…
- Trial name
- NCT04281017
- Testing
- TIVA, Balanced anesthesia
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pain, Postoperative
Efficacy of Transversus Abdominis Plane Block Versus Local Injection of Pain Medication
The purpose of this study is to determine if there is a better method of administering pain medication prior to minimally invasive gynecological surgery so that postoperative pain and/or narcotic usage may be minimized.
- Trial name
- NCT02314104
- Testing
- ropivacaine
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Liberman, Eric, D.O.
Fallopian Tube Cancer, Ovarian Sarcoma
Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies
RATIONALE: Stereotactic radiosurgery can send x-rays directly to the tumor and cause less damage to normal tissue. PURPOSE: This clinical trial studies stereotactic radiosurgery using CyberKnife works in treating women with…
- Conditions
- Fallopian Tube Cancer, Ovarian Sarcoma, Ovarian Stromal Cancer, Recurrent Cervical Cancer
- Trial name
- NCT01079832
- Testing
- stereotactic radiosurgery, quality-of-life assessment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Case Comprehensive Cancer Center
Opioid Substitution Treatment
ICE-T Pain Regimen for Total Laparoscopic Hysterectomy
The purpose of this randomized controlled trial is to determine whether, "ICE-T," a multimodal postoperative pain regimen composed of around the clock ice packs, toradol, and tylenol, has improved pain control compared to the…
- Trial name
- NCT03987022
- Testing
- Ketorolac, Opioids, Ice Packs
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- MetroHealth Medical Center
Pain
Lidocaine and Outpatient Gynecologic Laparoscopy
Although ambulatory gynecological laparoscopy is considered to be a minimally invasive surgical procedure, only 60% of patients undergoing this procedure are satisfied with postoperative pain control.
- Trial name
- NCT01250002
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Northwestern University
Cervical Cancer, Endometrial Cancer
Fondaparinux in Preventing Blood Clots in Patients Undergoing Surgery for Gynecologic Cancer
RATIONALE: Fondaparinux may help prevent blood clots from forming in patients who are undergoing surgery for gynecologic cancer.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00381888
- Testing
- fondaparinux sodium
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Postoperative Pain, Hysterectomy
Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery
This study will be investigating the efficacy and safety administration of multiple doses of intravenous (IV) acetaminophen (IVAPAP) in the 48 hour period following Gynecologic Surgery.
- Trial name
- NCT00399568
- Testing
- IV Acetaminophen
- Where
- 27 sites in United States
- Volunteers
- 331 people
- Sponsor
- Mallinckrodt
Intraoperative Complication, Malignant Female Reproductive System Neoplasm
Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery
This randomized clinical trial studies epidural anesthesia within an enhanced recovery pathway (ERP) in reducing pain in patients undergoing gynecologic surgery.
- Conditions
- Intraoperative Complication, Malignant Female Reproductive System Neoplasm, Pain
- Trial name
- NCT02423876
- Testing
- Epidural analgesia, Intraoperative Complication Management and Prevention, Pain Therapy
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Wisconsin, Madison
Pelvic Organ Prolapse, Urinary Incontinence
Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures
This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Pelvic Floor Disorders, Gynecologic Disease
- Trial name
- CLNUP (NCT04048356)
- Testing
- Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of New Mexico