Clinical trials: Gut Motility
Neurodegenerative Diseases, Parkinson Disease
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
MARKERS-NDD is a prospective, observational, longitudinal study, which aims to collect data from patients affected by neurodegenerative diseases (NDD) followed longitudinally for routine examinations performed as part of normal…
- Conditions
- Neurodegenerative Diseases, Parkinson Disease, Synucleinopathies, Lewy Body Disease
- Trial name
- MARKERS-NDD (NCT06596746)
- Testing
- Observation
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Casa di Cura San Raffaele Cassino
Body Weight, Post-Op Complication
Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)
This Study aims to develop machine learning models with the ability to predict patients' BMI and complications after Bariatric Surgery (CABS-Score).
- Conditions
- Body Weight, Post-Op Complication, Anastomosis, Leaking, Hiatal Hernia
- Trial name
- NCT05710913
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Dr. Med Anas Taha
Constipation, Analgesia
Enteral Naloxone Versus a Traditional Bowel Regimen for the Prevention of Opioid Induced Constipation in Trauma Patients
The purpose of this study is to determine if enteral naloxone is more effective than a traditional bowel regimen in the prevention and treatment of constipation and impaired gastric motility in critically ill trauma patients.
- Trial name
- NCT00799201
- Testing
- Naloxone and Docusate
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- CAMC Health System
Motility Disorders
Pilot of AbStats /AEGIS System for Detecting Motility Abnormalities
When compared to existing analyses: manometry, Smart Pill and lactulose breath testing, external Acoustic Esophago-Gastro-Intestinal Surveillance (AEGIS) may identify unique audible patterns characteristic of features of…
- Trial name
- AEGIS (NCT02233270)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cedars-Sinai Medical Center
Constipation
Probiotics for Alleviating Chronic Constipation in Adults
To investigate the clinical effects of probiotics in relieving intestinal motility and chronic constipation through regulating gut microbiota.
- Trial name
- NCT07152795
- Testing
- Probiotic
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Postoperative Ileus, Delayed Gastrointestinal Motility
Impact of Chewing Gum on Postoperative Gut Motility in Gastrointestinal Surgery Patients
Postoperative ileus (POI) is a frequent complication after abdominal surgery, leading to delayed gastrointestinal motility, prolonged hospital stay, and increased patient discomfort.
- Conditions
- Postoperative Ileus, Delayed Gastrointestinal Motility, Postoperative Gut Dysfunction
- Trial name
- NCT07425249
- Testing
- Chewing Gum
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Khyber Medical University Peshawar
Gum Chewing, Bowel Function
Gum Chewing And Bowel Motility in Patients Undergoing Cesarean Section. Kasr el Ainy Experience
The aim of the present study was to evaluate the effect of chewing gum on the recovery of bowel function after cesarean section in women.
- Trial name
- RCT (NCT02533830)
- Testing
- sugarless gum, traditional management
- Where
- 2 sites in Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Healthy
The Effect of Obeticholic Acid in Healthy Volunteers
This study investigates whether obeticholic acid affects gut microbiota, gastric motility, accommodation, and gastrointestinal peptide in healthy subjects. This study is a single-blind, placebo-controlled, randomized study.
- Trial name
- OCARINA (NCT05740631)
- Testing
- Ocaliva
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Tube Feeding
Effect of Methylnaltrexone (Relistor) on Digestion and Tolerance to Tube Feeding in Patients Treated With Opiates
It is hypothesized that using methylnaltrexone in addition to pain killer narcotics (opiates) in patients will result in increased tube feeding rates with more frequent nutrition at goal calorie rate.
- Trial name
- NCT01360372
- Testing
- Methylnaltrexone, Saline injection
- Where
- 2 sites in United States
- Sponsor
- Drexel University
Esophageal Disease
Efficacy of DA-5204 on Gastroesophageal Reflux Disease
This is a single-center, randomized, double-blind, placebo-controlled clinical Study to evaluate the efficacy of DA-5204 and proton pump inhibitor combination therapy compared with proton pump inhibitor alone therapy in patients…
- Trial name
- NCT03998969
- Testing
- Pantoprazole, DA-5204
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Functional Constipation
Lactobacillus Reuteri DSM 17938 in Functional Constipation
The diffusion of gastrointestinal (GI) chronic diseases is significantly increased during the last century in western countries.
- Trial name
- LRFC (NCT01244945)
- Testing
- L. reuteri DSM 17938
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Gastrointestinal Motility Disorder
Intestinal Dysmotility in Patients With Functional Digestive Symptoms
Automatic and non-invasive diagnostic methods based on the analysis of internal (intraluminal) and external (abdominal) images have been recently developed to measure intestinal motility.
- Trial name
- NCT04764019
- Testing
- High resolution intestinal manometry
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Post Abdominal Surgery, Gastrointestinal Motility Disorder
Association Between Preoperative Mediterranean Diet Adherence and Postoperative Bowel Motility
Postoperative bowel motility is an important indicator of recovery after abdominal surgery and may be influenced by preoperative nutritional status.
- Conditions
- Post Abdominal Surgery, Gastrointestinal Motility Disorder, Postoperative Ileus
- Trial name
- NCT07808281
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bahçeşehir University
Dyspepsia, Malabsorption Syndrome
Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children
There is some controversy in the medical literature regarding the effectiveness of topical lidocaine in children as an adjuvant drug to upper gastrointestinal endoscopy.
- Conditions
- Dyspepsia, Malabsorption Syndrome, Gastroesophageal Reflux Disease, Abdominal Pain
- Trial name
- NCT00521703
- Testing
- Lidocaine, Tannic acid
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Hospital Infantil Cândido Fontoura
Hirschsprung's Disease
Effects of Butyrate Enemas on Postoperative Intestinal Motility Disorders in Hirschsprung's Disease
Hirschsprung's disease (HD) is a rare congenital disorder (1/5000) defined by the absence of ganglion cells in the submucosal and myenteric plexuses along a variable length of the digestive tract.
- Trial name
- Buty-Hirsch (NCT03660176)
- Testing
- Sodium Butyrate, routine management
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Functional Gastrointestinal Disorders, Overlap Syndromes
Overlap FGIDs and Genetic Polymorphism
1. To analyze the prevalence of overlap syndromes among NERD or RH, FD, and IBS patients, and to identify and to compare the differences in their characteristics and symptoms, and to determine their risk factors. 2.
- Trial name
- NCT04712617
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Gastroesophageal Reflux
MSG and Gastrointestinal Motility
The purpose of this study is to clarify the physiological function of sodium glutamate by measuring its effect on upper GI motility ( gastric emptying).
- Trial name
- NCT01009658
- Testing
- Monosodium glutamate, Sodium chloride
- Where
- Japan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gunma University
Peptic Ulcer, Gastroesophageal Reflux
S-CEI of Nexium in Paediatric Patients
To capture safety and efficacy when Nexium are administered to pediatric patients in clinical practice after launch
- Trial name
- NCT03562026
- Where
- 31 sites in Japan
- Volunteers
- 240 people
- Sponsor
- AstraZeneca
Complications; Cesarean Section
Insitu Repair Versus Uterine Exeriorization During Cesarean Section
Two types of uterine repair described during cesarean section, the investigators will try to compare between the two techniques.
- Trial name
- NCT01723605
- Testing
- insitu repair, exteriorisation of the uterus
- Where
- Egypt
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cairo University
Atrial Fibrillation Ablation Procedure
Atrial Fibrillation Ablation on Gastric Motility "The AF Gut Study"
You are being scheduled to undergo an ablation procedure to treat your atrial fibrillation. Complications of ablation procedures include damage to structures near the heart from the heat energy used during the ablation procedure.
- Trial name
- NCT01396356
- Testing
- GI procedures
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dhanunjaya Lakkireddy, MD, FACC