Clinical trials: Gum Inflammation
Dental Plaque, Gingivitis
A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
The aim of this 12-week clinical study is to evaluate the ability of an experimental mouthwash, containing 0.085 percent (%) Cetylpyridinium chloride (CPC) as an adjunct to toothbrushing with a regular fluoride toothpaste, to…
- Trial name
- NCT06933368
- Testing
- Crest Cavity Protection Toothpaste, Experimental Mouthwash
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- HALEON
Gingivitis
Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis
The aim of this study is to evaluate the efficacy of a new interdental cleaning device (Soft-Picks Advanced), as compared to a leading brand floss; and, how ease of use can promote the establishment of a hygienic routine of…
- Trial name
- NCT02883244
- Testing
- Soft-Picks Advanced, Floss
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sunstar Americas
Gingivitis
Compare Anti-inflammatory Dentifrices
Plaque induced gingivitis
- Trial name
- NCT00762528
- Testing
- Triclosan/Copolymer/fluoride toothpaste, Sodium monofluorophosphate toothpaste
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers
The purpose of this study is to investigate the effectiveness of usage of a range of oral products (toothpaste, mouth rinse, denture cleanser) on the oral health of partial denture wearers compared to existing oral hygiene…
- Trial name
- NCT04290624
- Testing
- Experimental Dentifrice: Stannous Fluoride, COREGA Denture Foaming Cleanser, Mouth rinse: Sodium Fluoride
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Plaque, Gingivitis
Six Month Plaque and Gingivitis Study Using Colgate Total Toothpaste
The objective of this randomized, single center, parallel clinical research study is to evaluate the comparative efficacy performance of three dentifrices -Colgate Total Toothpaste, Parodontax Toothpaste and Colgate Cavity…
- Trial name
- NCT02080273
- Testing
- Colgate Cavity Protection toothpaste, Colgate Total toothpaste, Parodontax toothpaste
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
Philips AirFlosser Study
In the current study, Sonicare AirFloss (AF) will be used in combination with a Manual Toothbrush (MTB) in a population of manual toothbrush users who are irregular flossers and who exhibit signs of moderate gingivitis.
- Trial name
- NCT01700348
- Testing
- Airflosser, Manual Floss
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Tufts University
Dental Plaque and Gingivitis
The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis
This is a six (6) month, double-blind, parallel, controlled clinical trial utilizing one hundred and sixty (160) adults to evaluate the reduction of dental plaque and gingivitis.
- Trial name
- NCT02243046
- Testing
- Control toothpaste, Experimental toothpaste, Active Comparator
- Where
- Dominican Republic
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque
Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes
The objective is to compare two commerical oral products for the treatment of gingivitis.
- Trial name
- NCT00762515
- Testing
- Fluoride, Triclosan
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and Gingivitis
The objective of this clinical research study is to assess the efficacy of three oral hygiene multi-component regimens encompassing the use of a manual toothbrush, toothpaste and a mouthwash in controlling established dental…
- Trial name
- NCT02193165
- Testing
- triclosan/fluoride toothpaste + cetylpyridinium chloride Mouthwash, stannous fluoride toothpaste + cetylpyridinium chloride Mouthwash, fluoride toothpaste + fluoride Mouthwash
- Where
- Puerto Rico
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Plaque
Measuring Efficacy of an Oral-Irrigator After Three Weeks of Use
The primary objective of this exploratory study is to evaluate the efficacy of an Oral Irrigator in the reduction of gingivitis compared to a negative control over a 3 week period by using the Modified Gingival Index and the…
- Trial name
- NCT04899440
- Testing
- Water Flosser, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingival Inflammation and Bleeding, Dental Plaque
Clinical Efficacy Evaluation of Three Dentifrices
Clinical study to evaluate and compare the efficacy of two baking soda containing dentifrices, containing 20% and 35% baking soda, to a non-baking soda dentifrice for their ability to reduce gingivitis and plaque following…
- Trial name
- NCT03988374
- Testing
- Dentifrices
- Where
- Canada
- Volunteers
- 319 people
- Sponsor
- Church & Dwight Company, Inc.
Gingivitis
Iranian Traditional Mouth Rinse Punica Granatum Pleniflora (Golnaar) in Treatment of Gingivitis in Diabetic Patients
This is a triple-blinded randomized clinical trial to evaluate the effect of an Iranian traditional mouth rinse (Punica granatum Pleniflora or "Golnaar" mouthrinse) on treatment of diabetic gingivitis and compare it with…
- Trial name
- Golnaar (NCT02227485)
- Testing
- Punica granatum Pleniflora (Golnaar) mouth rinse, Chlorhexidine (0.2%), Tooth bleaching
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shiraz University of Medical Sciences
Halitosis
A Clinical Study to Examine the Effects of an Experimental Toothpaste Compared to a Regular Fluoride Toothpaste on Breath Odor in a Population With Gingivitis
The purpose of this study is to investigate the efficacy of an experimental dentifrice, containing 0.454 percent (%) stannous fluoride and 0.3% zinc chloride, to reduce oral malodor, compared to a marketed regular fluoride…
- Trial name
- NCT05524948
- Testing
- Experimental Dentifrice, Reference Dentifrice
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- HALEON
Caries, Gingivitis
Efficacy of an Antibacterial Toothpaste and Patients' Satisfaction
The primary objective of this randomized controlled clinical trial (RCCT) will be to compare the efficacy in reducing the quantity of Streptococcus mutans (S.
- Trial name
- NCT05569850
- Testing
- Brushing
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Dental Devices, Home Care
Study of an Experimental Toothbrush for Treatment and Prevention of Gingivitis
This study is 6 weeks long with 6 visits to a clinical site. People participating in this study will be asked to brush their teeth two times a day with a provided toothbrush.
- Trial name
- NCT01224158
- Testing
- Experimental Power Toothbrush, Flat trimmed Manual Toothbrush
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Gingivitis
Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease
This will be a single-center, 12 week, examiner-blind, randomized, stratified (gender and baseline mean whole mouth MGI score), two-treatment, parallel group, clinical study in healthy adult volunteers with moderate gingivitis.
- Trial name
- NCT02750943
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Peridontitis Patients, Chronic Gingivitis
Effect of Non-surgical Periodontal Therapy on Gingival Crevicular Fluid Interleukin-21 Levels
Human IL-21 is present in gingival crevicular fluid in periodontal health, gingivitis and chronic periodontitis. A significant increase in the concentration of IL-21 in gingival crevicular fluid is observed with an increase in…
- Conditions
- Chronic Peridontitis Patients, Chronic Gingivitis, Healthy
- Trial name
- NCT02861937
- Testing
- non surgical periodontal therapy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Gingivitis
A Clinical Trial to Evaluate Long-term Efficacy and Safety of Lozenges Containing Lactobacilli Reuteri (Prodentis™) on Gingivitis
The purpose of this study is to evaluate the long-term efficacy and safety of lozenges containing probiotics in reducing gingivitis. The primary purpose of this study is to support claims from U.S.
- Trial name
- NCT01811316
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Sunstar Americas
Dental Plaque, Gingivitis
A Clinical Study Investigating the Effect of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health
The aim of this 4-week clinical study is to evaluate the ability of an experimental toothpaste, containing 0.454 percent (%) Stannous Fluoride (SnF2), 0.3% Zinc Chloride (ZnCl2) and 1% Alumina, to improve gingival health and…
- Trial name
- NCT06602466
- Testing
- Test toothpaste, Colgate Cavity Protection Toothpaste
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Plaque, Gingivitis
A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
The aim of this study is to assess the ability of a marketed Cetylpyridinium Chloride (CPC) mouthwash alongside a marketed Stannous Fluoride (SnF2) toothpaste in improving gingival health and reducing plaque accumulation…
- Trial name
- NCT06660069
- Testing
- Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste), CPC Mouthwash (Parodontax Active Gum Health Mouthwash), Regular Fluoride Toothpaste (Crest Cavity Protection)
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- HALEON