Clinical trials: Gulf War Syndrome
Gulf War Syndrome
Glutamate Neuro-Excitotoxicity in GWI
The objective of the proposed research is to examine whether dietary exposure to food additives containing glutamate may be contributing to symptoms in Gulf War Illness (GWI).
- Trial name
- GWI (NCT03342482)
- Testing
- Low-glutamate diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- American University
Post-traumatic Stress Disorder, Persian Gulf Syndrome
Sentra AM® and Sentra PM® for Post-traumatic Stress Disorder (PTSD) and Gulf War Fibromyalgia (GWF)
An open-label clinical outcomes study to determine the safety and efficacy of Sentra AM® and Sentra PM® for post-traumatic stress disorder (PTSD) and Gulf War fibromyalgia (GWF).
- Trial name
- GWF001 (NCT01437891)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stephanie Pavlik
Gulf War Illness
Probiotic (VSL #3) for Gulf War Illness
The overall objective is to determine whether VSL #3 will improve 1) intestinal symptoms of Irritable Bowel Syndrome (IBS) and 2) non-intestinal symptoms (fatigue, joint pain, insomnia, general stiffness and headache) associated…
- Trial name
- NCT02011542
- Testing
- VSL#3
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Utah
Chronic Fatigue Syndrome, Fibromyalgia
Compare the Medical Conditions of Gulf War Veterans to Non-Deployed Veterans
Primary Hypothesis: Gulf War veterans will have an equal prevalence or mean level of the following medical and psychological conditions frequently reported in the literature compared to a control group of nondeployed veterans…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Post-Traumatic Stress Disorder, Neurologic Abnormalities
- Trial name
- NCT00032461
- Volunteers
- 2,000 people
- Sponsor
- US Department of Veterans Affairs
Gulf War Illness
Multimodal Investigation of the Neuroprotective Effects of Resveratrol (MINER)
Since their return from military service in the 1990-1991 Gulf War, many Veterans have been affected by debilitating symptoms that are not easily explained.
- Trial name
- MINER (NCT03665740)
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- VISN 17 Center of Excellence
Gulf War Syndrome
Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome
The main goal of the proposed study is to critically evaluate a nonpharmacological and readily available therapy, cranial electrical stimulation (CES) using Alpha-Stim™, and to discover the brain function mechanisms underlying…
- Trial name
- NCT07151248
- Testing
- Cranial electrical/electrotherapy stimulation (CES)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Gulf War Syndrome, Persian Gulf Syndrome
Mitochondrial Cocktail for Gulf War Illness
The purpose of this study is to develop preliminary evidence, such as effect size and variance estimates, to guide successful conduct of a properly-powered clinical trial to assess the benefit of a mitochondrial cocktail…
- Conditions
- Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorders
- Trial name
- NCT02804828
- Testing
- Individualized mitochondrial cocktail
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Diego
Gulf War Syndrome, Headache
Alleviating Headache and Pain in GWI With Neuronavigation Guided rTMS
This study aims to assess the effect of repetitive transcranial magnetic stimulation (rTMS) on Gulf War illness related headaches and pain.
- Trial name
- NCT03030794
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Veterans Medical Research Foundation
Gulf War Syndrome
Assessing Neuroinflammation in GWI Using MRS
The primary aim of this study is to determine if Gulf War Illness (GWI) likely involves neuroinflammation. The investigators hypothesize that GWI involves neuroinflammation.
- Trial name
- NCT04638998
- Testing
- Magnetic Resonance Spectroscopic Imaging, Blood draw
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gulf War Illness
Probiotic (Visbiome) for Gulf War Illness
The overall objective is to determine whether Visbiome will improve 1. intestinal symptoms of Irritable Bowel Syndrome (IBS) and 2.
- Trial name
- NCT03078530
- Testing
- Visbiome, VSL#3
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ashok Tuteja
Persian Gulf Syndrome, Gulf War Syndrome
Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness
This unblinded Phase II clinical trial will test the effects of individualized acupuncture treatments offered in extant acupuncture practices in the community; practitioners will have had at least 5 years of experience plus…
- Conditions
- Persian Gulf Syndrome, Gulf War Syndrome, Multiple Chronic Illnesses, Occupational Diseases
- Trial name
- CARE (NCT06716411)
- Testing
- Acupuncture
- Where
- 10 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Gulf War Syndrome
Pycnogenol (French Maritime Pine Bark) for the Treatment of Gulf War Illness
The purpose of this research study is to determine how pycnogenol may reduce Gulf War Illness (GWI) symptom severity. The study will also examine the safety of this treatment and determine the optimal dosage.
- Trial name
- NCT07266571
- Testing
- Pycnogenol, 100mg, Pycnogenol, 200mg, Pycnogenol, 400mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Gulf War Syndrome, Persian Gulf Syndrome
Coenzyme Q10 for Gulf War Illness: A Replication Study
The purpose of this study is to assess whether a high quality preparation of ubiquinone (coenzyme Q10) benefits symptoms, function, and quality of life in veterans with Gulf War illness.
- Conditions
- Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorder, Respiratory Chain
- Trial name
- NCT06515184
- Testing
- PharmaNord Bio-Quinone Active CoQ10 Gold 100mg
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of California, San Diego
Gulf War Syndrome
Bacterial Overgrowth Associated With Chronic Multisymptom Illness Complex
The adverse impact of Gulf War Syndrome (GWS) on the health of veterans and on the resources of the VA Healthcare System underscores the need to resolve its underlying cause.
- Trial name
- NCT00956150
- Testing
- Lactulose Breath Test, Rifaximin
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Henry C. Lin, MD
Gulf War Syndrome
Follow-up of Psychological and Neurocognitive Gulf War Outcome: Relation to Stress
This is the follow-up to an observational epidemiological study of psychological and neuropsychological outcomes of deployed and non-deployed Gulf War-era veterans.
- Trial name
- NCT00018707
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Persian Gulf Syndrome
Mindfulness-Based Stress Reduction for Gulf War Syndrome
This pilot study is a two arm randomized, controlled clinical trial that evaluated whether a standardized Mindfulness-Based Stress Reduction (MBSR) intervention reduces symptoms associated with Gulf War Syndrome (GWS) more…
- Trial name
- NCT01267045
- Testing
- Mindfulness-based stress reduction
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- US Department of Veterans Affairs
Gulf War Syndrome, Gulf War Illness
Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms
This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain.
- Conditions
- Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain
- Trial name
- NCT04182659
- Testing
- Transcranial Magnetic Stimulation
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Veterans Medical Research Foundation
Persian Gulf Syndrome, Chronic Fatigue Syndrome
Acupressure for Pain Management and Fatigue Relief in Gulf War Veterans
This study will provide symptomatic veterans with acupressure treatment and determine its effectiveness in fatigue relief and pain management for Gulf War Illness (GWI).
- Trial name
- NCT02075489
- Testing
- Acupressure treatment., Reiki
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The Cleveland Clinic
Persian Gulf Syndrome, Mycoplasma Infections
Antibiotic Treatment of Gulf War Veterans' Illnesses
In 1990 and 1991, the U.S. deployed approximately 700,000 troops to the Persian Gulf to liberate Kuwait from Iraqi occupation. While there were few casualties associated with the Gulf War, many individuals returned from this…
- Trial name
- NCT00007735
- Where
- 27 sites in United States, Puerto Rico
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Apnea, Sleep, Chronic Fatigue Syndrome
Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
The purpose of this study is to determine any sleep disordered breathing in veterans with Gulf War Syndrome (GWS) and compare it to healthy normal asymptomatic Gulf War veterans.
- Trial name
- NCT00252629
- Testing
- Nasal CPAP treatment during sleep
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- US Department of Veterans Affairs