Clinical trials: Guideline Implementation
Implementation of a Chronic Disease Management Programme, COPD
Effects of an Active Implementation of a Guideline for Chronic Obstructive Pulmonary Disease
Aims: To design a proactive implementation strategy for a chronic-disease-management-programme. To describe effects of the active implementation of a programme for COPD-patients measured on patient-related goals and use of health…
- Trial name
- NCT01228708
- Testing
- Active implementation of a guideline for chronic disease
- Volunteers
- 3,021 people
- Sponsor
- University of Aarhus
Pain, Back
Implementation of the ACP Guideline for Low Back Pain (IMPACt-LBP)
The purpose of this study is to assess whether the primary spine practitioner (PSP) model of care will lead to improvements in patient outcomes, as compared to usual care, based on change in patient-reported PROMIS Pain…
- Trial name
- IMPACt-LBP (NCT05626049)
- Testing
- Primary Spine Provider Model, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 1,800 people
- Sponsor
- Duke University
Heart Failure With Reduced Ejection Fraction
Email Nudges to Improve GDMT (MRA) Adherence in Heart Failure
The Email Nudges to Improve GDMT (MRA) Adherence in Heart Failure (ENIGMA-HF) study is a pragmatic parallel-arm randomized control trial of a quality improvement (QI) intervention involving email nudges to cardiology clinic…
- Trial name
- ENIGMA-HF (NCT05806970)
- Testing
- Email Nudge
- Where
- United States
- Sponsor
- University of California, Los Angeles
Cervical Cancer Screening, Gynecologic Cancers
Compliance to Cervical Cancer Chemoradiation Guidelines: A Multicentric Implementation Audit and Resource Assessment Initiative of National Cancer Grid of India
This is a combination of retrospective and prospective observational study that will be performed across NCG and other participating centers to report compliance to chemoradiation for cervical cancer.
- Conditions
- Cervical Cancer Screening, Gynecologic Cancers, Treatment Compliance, Chemoradiotherapy
- Trial name
- NCG-Compliance (NCT07290972)
- Testing
- Not applicable- observational study
- Where
- 2 sites in India
- Volunteers
- 618 people
- Sponsor
- Tata Memorial Hospital
Mental Disorder, Stress
Exploring Effectiveness and Mechanism of Change of an Implementation Strategy on Guideline Implementation in Schools
This project is a two-armed randomized-controlled trial exploring the effectiveness and mechanisms of change of two different implementation strategies for implementing the Guideline for the prevention of mental ill-health at the…
- Trial name
- NCT05019937
- Testing
- Educational meeting, Implementation team, Workshops
- Where
- Sweden
- Volunteers
- 2,276 people, healthy volunteers welcome
- Sponsor
- Lydia Kwak
Psychotic Disorders
Implementation of National Guidelines for Treatment of Psychoses
The study is a combined health services research study and a clinical patient outcomes sub-study. The aims of the study are to give new knowledge on (RQ1) current implementation in mental health services of four evidence based…
- Trial name
- NCT03271242
- Testing
- Systematic implementation support, No implementation support
- Volunteers
- 325 people
- Sponsor
- University Hospital, Akershus
Hypertension
Enhancing Systems of Care to Improve Hypertension Guideline Implementation
This study is a prospective cluster randomized trial testing a systems-level strategy to implement current American Heart Association hypertension guidelines in African American communities at risk for cardiovascular related…
- Trial name
- NCT03563872
- Testing
- Intervention, Active Comparator
- Where
- United States
- Sponsor
- Henry Ford Health System
Low Back Pain
Guideline Implementation in Physiotherapy
The purpose of this study is 1) to develop an intervention strategy to increase physiotherapists' adherence to evidence-based practice guidelines, 2) to try out this intervention on a small scale to determine what efficacy may be…
- Trial name
- GIPhT (NCT00962169)
- Testing
- Behavioral and managerial, Behavioral and IT
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Spinal Cord Injuries, Aging
Exercise and Nutrition Education for Older Adults With Spinal Cord Injury: A Pilot Randomized Controlled Trial
Older adults living with a spinal cord injury (SCI) experience an increased burden of secondary health conditions than, coupled with age-related complications, may negatively affect physical and mental health, as well as…
- Trial name
- NCT07845851
- Testing
- Individualized Exercise Training, Nutrition Education, Behavioral Support
- Volunteers
- 24 people
- Sponsor
- Wayne State University
Smoking Cessation, Randomized Controlled Trial
Facilitating Implementation of the PHS Smoking Cessation Guidelines - RESET
The adverse impact of tobacco use on disease prevalence and health care costs is well documented. Hence, finding effective ways to reduce tobacco dependence is an essential component of improving the outcomes, quality and…
- Trial name
- NCT00057070
- Testing
- Smoking cessation information, collection, and dissemination
- Where
- 2 sites in United States
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Heart Disease, Heart Failure
Non-interventional Study on Guideline Directed Medical Therapy for Patients With Heart Failure (HF) in Germany
Heart failure (HF) is a global public health issue that affects more than 63 million people worldwide. The clinical and economic burden of HF on health care systems is substantial.
- Conditions
- Heart Disease, Heart Failure, Cardiovascular Disease, Heart Failure, Systolic
- Trial name
- PHRASE-HF (NCT06675552)
- Where
- 6 sites in Germany
- Volunteers
- 338 people
- Sponsor
- AstraZeneca
Heart Failure
A Study of Accelerated Guideline-Directed Medical Therapy for Heart Failure
The aim of the study was to evaluate the efficacy and safety of a Guideline-Directed Medical Therapy (GDMT) clinic within a general cardiology practice relative to usual care.
- Trial name
- NCT07217106
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
Implementation of Machine Learning and Hemodynamic Profiles Based Clinical Decision Support Systems for Personalized Guideline Accordant Antihypertensive Regimens in Primary Care: a Pragmatic Cluster Randomized Controlled Trial
This trial is a prospective, multicenter, single-blind, three-arm parallel-group, cluster randomized controlled trial assessing the effectiveness and safety of two types of CDSS in primary care settings in China.
- Trial name
- NCT06828692
- Testing
- Group A (clinical guideline+machine learning), Group B (clinical guideline+impedance cardiograph+machine learning), Group C (usual care)
- Where
- China
- Volunteers
- 2,160 people
- Sponsor
- China National Center for Cardiovascular Diseases
Chronic Heart Failure
Computerized Guideline in Heart Failure: Implementation Process and Impact Evaluation
Objective: To assess the effectiveness of implementation process of an electronic Heart Failure guideline in primary care in the city of Barcelona.
- Trial name
- NCT00792402
- Where
- Spain
- Volunteers
- 13,008 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Neonatal Patients Undergoing Major Non-cardiac Surgery, Congenital Anomaly
Neonatal Enhanced Recovery After Surgery (ERAS) Outcomes Study
The goal of this observational study is to improve the way newborn babies are cared for before, during, and after major surgery. Surgery can be very stressful on a baby's body.
- Trial name
- NEO (NCT07771478)
- Testing
- Pre-nERAS Guideline Implementation Intervention, Multifaceted Implementation of nERAS Guideline Intervention
- Where
- 3 sites in Canada, United Kingdom
- Volunteers
- 400 people
- Sponsor
- The Hospital for Sick Children
Survivorship, Cancer
ONLOOP Trial: Evaluating a New Surveillance and Support System for Survivors of Childhood Cancer in Ontario
The treatments that aim to cure cancer in children can lead to "late effects" such as second cancers and heart disease. Screening tests can help find late effects, but most adult survivors of childhood cancer do not complete…
- Conditions
- Survivorship, Cancer, Heart Diseases, Secondary Cancer
- Trial name
- NCT05832138
- Testing
- ONLOOP program
- Volunteers
- 900 people
- Sponsor
- The Hospital for Sick Children
Heart Failure
Registry BAsed Optimization Of Therapy in Heart Failure
Rationale. Although several pharmacological treatments, namely renin-angiotensin-system inhibitors, sacubitril/valsartan, beta-blockers, mineralocorticoid receptor antagonists and sodium-glucose cotransporter-2 inhibitors…
- Trial name
- REBOOT-HFrEF (NCT07154758)
- Testing
- Screening for need of HFrEF GDMT implementation through SwedeHF
- Where
- 6 sites in Sweden
- Volunteers
- 1,000 people
- Sponsor
- Region Stockholm
Endometrial Neoplasm
Follow-up Care After Treatment for Endometrial Cancer
The purposes of this study are to examine the needs (symptoms, support, information) and satisfaction of women during follow-up in the community after completing treatment for endometrial cancer.
- Trial name
- NCT00750672
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis, Knee, Osteoarthritis, Hip
Improve Osteoarthritis Care
The purpose of The Improve Osteoarthritis Care study is to improve the quality of osteoarthritis care in Norwegian primary care, by increasing the use of recommended treatment modalities and improving patient access to…
- Trial name
- NCT04670549
- Testing
- Implementation of treatment guidelines
- Where
- Norway
- Volunteers
- 1,541 people
- Sponsor
- Diakonhjemmet Hospital
Actinic Keratoses
Implementation of Actinic Keratosis Guideline Among General Practitioners.
This study investigates 5-fluorouracil cream prescription trends by general practitioners for the treatment of field changes of actinic keratosis over the years 2016-2021.
- Trial name
- NCT05976048
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Maastricht University Medical Center