Clinical trials: Glycemic Variation
Obesity, Inflammatory Markers
Time-Restricted Feeding
We propose to conduct a randomized 6-day isocaloric crossover feeding study in humans with prediabetes and obesity. We will study the effect of restricting the timing of caloric intake to earlier in the day (TRF) versus later in…
- Conditions
- Obesity, Inflammatory Markers, Glycemic Variation, Time Restricted Feeding
- Trial name
- TRIO (NCT04884659)
- Testing
- Time restricted feeding arm, usual feeding pattern arm
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Critical Illness
Glycemic Index Variation During Low-carbohydrate Enteral Formula With and Without Fructose in Critically Ill Patients
Hyperglycemia is a known risk factor for mortality in critically ill patients. Most of these patients receive enteral feeding. There is controversy about ideal carbohydrate composition of these diets.
- Trial name
- NCT03003507
- Testing
- Enteral Formula With Fructose, Enteral Formula Without Fructose
- Volunteers
- 25 people
- Sponsor
- Hospital Moinhos de Vento
Diabetes Mellitus, Bariatric Surgery Candidate
Glycemic Index Variations In the Early Period Following Bariatric Surgery
The diverse community of gut microbes commonly referred to as the 'gut microbiome', is increasingly suggested to play significant roles in health and disease, and to affect even distant non-GI organs by metabolite signaling.
- Trial name
- NCT04263168
- Testing
- Continuous Glucose monitoring in the perioperative period
- Where
- Israel
- Sponsor
- Sheba Medical Center
Type 1 Diabetes, Exercise
Exercise-induced Glycemic Variations and Hybrid Closed-loop Systems
Type 1 diabetes is characterized by high risk of hypoglycemia and associated fear of hypoglycemia. Hypoglycemia risk is higher during and after physical activity, especially aerobic activity of long duration.
- Trial name
- SAFE-T1D (NCT05736263)
- Testing
- Moderate intensity exercise, High intensity interval exercise, Combined exercise
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
Type1diabetes
Glycemic Variations During the Menstrual Cycle in Women With Type 1 Diabetes
In clinical practice, women living with type 1 diabetes frequently report that insulin requirements change across the menstrual cycle. Consequently, glycemic fluctuations are observed.
- Trial name
- GLYMETY (NCT05258292)
- Testing
- Continuous glucose monitoring, Insulin, Premenstrual symptoms
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Carbohydrate Intolerance
Effect of Genetic Variation in Starch-digesting Enzymes on Digestibility and Glycemic Index of Cold and Hot Rice
This study evaluates the effect of different methods of preparation (cooked and consumed hot vs cooked, cooled overnight and consumed cold) and variation in the activity of salivary amylase on the glycemic index and carbohydrate…
- Trial name
- NCT03667963
- Testing
- Glucose, Glucose plus lactulose, Hot Rice
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy, Hunger
Metabolic Response to Variations in Dietary Glycemic Index
The goal of this study is to compare metabolic response to variations in dietary glycemic index in healthy participants. The main questions it aims to answer are: What are the metabolic hunger and food intake responses to…
- Conditions
- Healthy, Hunger, Food Preferences
- Trial name
- NCT05804942
- Testing
- High glycemic index, Medium glycemic index, Low glycemic index
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Diabetes, Chemotherapy
Study on Glycemic Variations in Diabetic Patients Treated With Chemotherapy: Benefit of Continuous Interstitial Glucose Measurement
Over the last years, there has been a progressive increase in the prevalence of diabetes. Approximately 3.3 million French adults and approximately 425 million adults worldwide have been diagnosed with diabetes.
- Conditions
- Diabetes, Chemotherapy, Interstitial Glycemia, Freestyle
- Trial name
- ONCODIAB (NCT04315857)
- Testing
- interstitial glycaemia
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Infant Conditions, Glucose Intolerance
Monitoring of Postprandial Glycemic Variability in Healthy Young Infants
To measure and quantify the postprandial glucose variations in response to a meal in the healthy 6-12 months old child and correlate this response with the composition of this meal.
- Trial name
- IGVM (NCT03819725)
- Testing
- Glucose monitoring
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Type 2 Diabetes
Genetic Variation in the Transporters and Hypoglycemic Agents
Type 2 diabetes have become a major global health problem. Currently, metformin is used as first-line therapy in combination with lifestyle changes, and sitagliptin can be added to metformin in case of insufficient glycemic…
- Trial name
- NCT01341795
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ajou University School of Medicine
Type 1 Diabetes
Do "sugar Swings" Impact the Brain Function and the Eating Behaviors of People with Type 1 Diabetes
In type 1 diabetes, it is common to choose the food we eat according to the blood sugar level and the insulin dose and vice versa.
- Trial name
- NCT05487534
- Testing
- Observational
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- Laval University
Type2 Diabetes
Effects of Replacing Lantus With Basalin on the Glycemic Variation in Patients With Type 2 Diabetes Mellitus
The study will assess the glycemic variationusing continuous glucose monitoring system in type 2 diabetic patients with euglycemia control respectively when patients was treated with Basalin and one week after changing the…
- Trial name
- NCT03631121
- Testing
- Basalin to Lantus
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Aerobic Exercise, Acute Exercise
Diurnal Variation of Exercise on Metabolic Health
The main objective of this project is to study the diurnal variation of the effect of exercise on glycemic metabolism and fat oxidation in humans.
- Conditions
- Aerobic Exercise, Acute Exercise, Circadian Rhythm Sleep-Wake Disorders, Unspecified Type, Glucose Metabolism
- Trial name
- DIVA (NCT05369715)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada