Clinical trials: Glaucoma Following Surgery
Glaucoma
Steroids Versus Non-steroidal Anti-inflammatory Drugs Following Glaucoma Surgery
This study aims to evaluate the eye pressure response to non-steroidal anti-inflammatory eye drops as compared to steroid eye drops following glaucoma surgery.
- Trial name
- NCT00956462
- Testing
- Ketorolac (NSAID) versus Dexamethasone (steroid)
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University Health Network, Toronto
Glaucoma, Adherence
Effect of SMS Reminder and Free Eye Drops on Follow-up Adherence After Trabeculectomy Surgery in Rural China
The purpose of the study is to use a randomized controlled design to determine the impact of a SMS messaging associated with free eye drops intervention on the following outcomes among patients after trabeculectomy surgery in…
- Trial name
- NCT02328456
- Testing
- SMS and free eye drops
- Where
- China
- Volunteers
- 209 people
- Sponsor
- Congdon Nathan
Primary Open Angle Glaucoma
Electroretinogram and Retinal Vascular Changes After Cataract Surgery
To compare electrophysiological and Optical coherence tomography angiography of optic disc and macula changes after uneventful phacoemulsification between normal and cataractus patients with primary open angle glaucoma.
- Trial name
- NCT05871034
- Testing
- phacoemulsification
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Glaucoma
Outflow Facility AIT vs Microshunt
The purpose of this study was to asses differences in nycthemeral (24-h) intraocular pressure (IOP) profiles and outflow facilities between patients who have undergone epibulbar microshunt implantation and ab interno…
- Trial name
- NCT05548959
- Testing
- Pneumatonometry after microshunt implantation, Pneumatonometry after ab interno trabeculectomy
- Where
- Germany
- Volunteers
- 68 people
- Sponsor
- Wuerzburg University Hospital
Ocular Surface Disease, Glaucoma, Open-Angle
Ocular Surface Disease Changes After iStent or iStent Inject Implantation With Phacoemulsification
This prospective interventional single-arm trial evaluates measures changes in ocular surface disease parameters in eyes with mild to moderate open-angle glaucoma (OAG) on 1-4 glaucoma medications who undergo phacoemulsification…
- Trial name
- NCT04452279
- Testing
- iStent or iStent inject implantation with concomitant cataract surgery
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Vance Thompson Vision
Glaucoma, Malignant Glaucoma
Study on Intraocular Structural Parameters and Surgical Effect Before and After the Onset of Malignant Glaucoma
In this retrospective observational study, we collected intraocular structure parameters of malignant glaucoma and primary angle closure glaucoma.
- Trial name
- MG (NCT04220879)
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Glaucoma Patients Scheduled for Trabeculectomy
Comparison of Two Method Antimetabolites Application on Corneal Function in Trabeculectomy Surgery
Application of antimetabolite agents such as mitomycin_c has improved trabeculectomy results and better control of intraocular pressure complications such as corneal endothelial cell loss.
- Trial name
- NCT01297803
- Testing
- Mitomycin_c
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Glaucoma, Filtering Surgery
Long-Term IOP Fluctuation and VF Progression After Triple Procedure
Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for…
- Conditions
- Glaucoma, Filtering Surgery, Intraocular Pressure
- Trial name
- NCT00428740
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Yonsei University
Cataract, Age-related Cataract
Association Between Light Spectrum and Survival After Cataract Surgery
This study was a retrospective observational cohort analysis of subjects aged 65 years and older, who underwent bilateral cataract surgery within a single (15 hospital) healthcare system, to determine the association between type…
- Conditions
- Cataract, Age-related Cataract, Circadian Rhythm Disorders, Glaucoma
- Trial name
- NCT04187157
- Testing
- Blue-light filtering intraocular lens, Conventional intraocular lens
- Where
- United States
- Volunteers
- 10,192 people
- Sponsor
- University of Pittsburgh
Cataract, Exfoliative Glaucoma
Measurement of Ocular Tensional Fluctuation by Triggerfish Lens Before and After Cataract Surgery in Patients With Exfoliative Glaucoma
Glaucoma is a very frequent disease in Brittany. In glaucoma the retinal ganglion cells and their axons slowly die with visible changes at the optic nerve head (cupping).
- Trial name
- TRIGGERFISH (NCT02658071)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Brest
Glaucoma
Tear Interleukin Biomarkers After Glaucoma Treatment
This prospective study aims to evaluate inflammatory biomarkers in tear fluid in patients with glaucoma undergoing micropulse transscleral cyclophotocoagulation (MP-CPC), continuous-wave cyclophotocoagulation (CPC), and…
- Trial name
- TIGT (NCT07592988)
- Testing
- MicroPulse Transscleral Cyclophotocoagulation, Conventional Transscleral Cyclophotocoagulation, Antiglaucoma Surgery
- Where
- Kazakhstan
- Volunteers
- 24 people
- Sponsor
- Kazakh Eye Research Institute
Glaucoma
Subconjunctival Bevacizumab to Prevent Bleb Failure After Glaucoma Filtration Surgery
This study analyzes the safety and efficacy of off-label Subconjunctival Injection of bevacizumab (Avastin) versus 0.02% mitomycin C (MMC) for preventing bleb failure following glaucoma filtration surgery.
- Trial name
- NCT00468429
- Testing
- Subconjunctival Bevacizumab
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Grewal Eye Institute
Glaucoma
Pilocarpine Use After Kahook Goniotomy
The goal of this study is to determine whether using pilocarpine provides added benefit to the success of combined cataract + Kahook Dual Blade (KDB) surgery.
- Trial name
- PAACK (NCT03933631)
- Testing
- Pilocarpine, Prednisolone, Ofloxacin
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- Montefiore Medical Center
Glaucoma
Proteomic Profiles in Trabeculectomy Patients
Approximately 70 million people world-wide are affected with glaucoma, of whom 6.7 million have bilateral blindness.5 Elevated intro-ocular pressure is the major modifiable risk factor in glaucoma, and reducing intraocular…
- Trial name
- NCT01841580
- Where
- Singapore
- Volunteers
- 36 people
- Sponsor
- Singapore National Eye Centre
Glaucoma, Primary Open Angle, Cataract
Investigate, Following Cataract Surgery With IOL in Conjunction With Intracanalicular Dexamethasone Insert
Randomized, controlled treatment with an intracanalicular dexamethasone (0.4mg) insert following cataract surgery with intraocular lens implant (IOL) combined with minimally invasive glaucoma surgery (MIGS), specifically iStent…
- Trial name
- NCT04465864
- Testing
- Intracanalicular Dexamethasone, 0.4 mg insert
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wolstan and Goldberg Eye Associates
Glaucoma Following Pediatric Cataract Surgery
Outcome of Gonioscopy-Assisted Transluminal Trabeculotomy in Pediatric Glaucoma Following Cataract Surgery.
This prospective case series evaluated the 12-month outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in children with glaucoma following cataract surgery (GFCS).
- Trial name
- (GATT in GFCS) (NCT07542522)
- Testing
- gonioscopy assissted transluminal trabeculotomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Glaucoma Secondary, Congenital Cataract
Quantitatively Analysis of Fundus Structure Characteristics in Glaucoma Following Congenital Cataract Surgery
To quantitatively analyze the fundus structure and microvascular characteristics of GFCS and non-GFCS (NGFCS) using optical coherence tomography angiography (OCTA), to explore the vascular-structural association, and to assess…
- Trial name
- NCT05446077
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Sun Yat-sen University
Glaucoma, Glaucoma, Open Angle
SOLX Gold Shunt Versus Control Implant: Randomized Trial for Refractory Glaucoma
Study Objective: To establish the substantial equivalence of the SOLX Gold Shunt to commercially available aqueous shunts, specifically the Ahmed™ Glaucoma Valve Model FP7, in the ability to reduce intraocular pressure (IOP)…
- Trial name
- NCT00382395
- Testing
- SOLX Gold Shunt GMS-plus, Ahmed FP7 Glaucoma Valve
- Where
- 15 sites in United States, Canada and 3 more
- Volunteers
- 180 people
- Sponsor
- SOLX, Inc.
Glaucoma, Cataract
Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery
In this study, the investigators are comparing dexamethasone ophthalmic insert (DEXTENZA®) to the current standard of care, prednisolone acetate 1% eye drops, in a glaucoma population receiving both cataract and…
- Trial name
- SUSTAIN (NCT04200651)
- Testing
- Dexamethasone Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The New York Eye Surgery Center
Angle-closure Glaucoma, Minimally Invasive Glaucoma Surgery
Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study
The drainage angle in the anterior chamber of the eye mediates the outflow of aqueous humor, and pathological changes here can lead to high intraocular pressure and glaucoma.
- Conditions
- Angle-closure Glaucoma, Minimally Invasive Glaucoma Surgery, Goniosynechialysis, Goniotomy
- Trial name
- NCT06492538
- Testing
- various types of angle interventions
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University