Clinical trials: Gingivitis
Periodontal Health, Gingivitis
Effect of Probiotics on the Periodontal Status of Orthodontic Patients
Gingival inflammation (gingivitis) is commonly reported in teenagers with fixed orthodontic devices (FOD). Indeed, FODs promote the accumulation of plaque and interfere with the efficacy of tooth brushing.
- Trial name
- POP (NCT04634201)
- Testing
- Oral probiotics (L. reuteri)
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Lille
Healthy
Can Saliva be the New Bio-fluid to Monitor Children's Oral Health?
Background: Salivary diagnosis is an emerging field; the potentially valuable biofluid contains many molecules of the systemic circulation. Still, its profile in health has been scarcely investigated.
- Trial name
- NCT05495373
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Tooth Discoloration, Periodontal Diseases
Evaluating the Efficacy of a Gum Health Formulation on Teeth Whitening in Patients With Gingivitis and Periodontitis
The purpose of this study is to evaluate the efficacy of a novel gum health formulation, when used in an intra-oral device or on a toothbrush, for teeth whitening and clinical improvements in periodontal diseases.
- Trial name
- NCT02906982
- Testing
- Gum health formulation in intra-oral device, Gum health formulation on toothbrush
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Glo Science, Inc.
Periodontal Diseases, Gingivitis
Comparative Evaluation of Antiplaque and Antigingivitis Efficacy of Ocimum Sanctum (Tulsi) Extract
Chlorhexidine is considered as gold standard for its antiplaque and antigingivitis efficacy till date but it has got many side effects.
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis
- Trial name
- NCT03474146
- Testing
- Ocimum sanctum, Chlorhexidine Gluconate, Propylene Glycol
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Gingivitis
Effect of Mouthrinsing on Inflammation of the Gums.
The purpose of this study is to determine whether rinsing with an amine fluoride/stannous flouride mouthrinse in addition to daily tooth brushing is more effective than tooth brushing alone.
- Trial name
- NCT01317446
- Testing
- amine fluoride/stannous fluoride
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Technische Universität Dresden
Gingivitis
Clinical Effectiveness of 5 Different Mouthwashes in the Treatment of Generalised Gingivitis
The aim of the present study is to evaluate the efficacy of 5 mouthwashes, based on different ingredients, in the treatment of generalised gingivitis.
- Trial name
- NCT04733196
- Testing
- Essential oils, Essential oils in combination with chlorhexidine 0,12%, Chlorhexidine 0,20 % in combination with aroma oils
- Where
- Bulgaria
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Periodontitis, Gingivitis
Diagnostic Accuracy of Rapid Non-clinical Screening Tests for Early Detection of Periodontitis
Gum disease is the 6th most prevalent disease of mankind. It is a non-communicable non-resolving inflammation; if untreated it leads to tooth loss and inability to chew properly.
- Trial name
- NCT03928080
- Testing
- Bleeding on brushing
- Where
- China
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Gingival Inflammation
Toothbrush Wear and Its Effect on Subgingival Inflammation Using Two Different Brushing Techniques
Toothbrush plaque removal, along with interproximal flossing, helps to maintain the oral cavity free from periodontal diseases and dental caries.
- Trial name
- NCT03158350
- Testing
- Instructed Brushing Method
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tufts University
Gingival Diseases, Gingivitis
Acquired Chronic Erosive Gingivitis: Clinical Relevance of Papillary Gingival Biopsy
Chronic erosive gingivitis is a syndrome (CEGS) that combines severe gingival inflammation and gingival erosion. The term "desquamative gingivitis" is often used in the literature to define chronic erosive gingivitis.
- Conditions
- Gingival Diseases, Gingivitis, Autoimmune Diseases, Oral Lichen Planus
- Trial name
- NCT04293718
- Testing
- papillary gum biopsies
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Plaque, Dental, Gingivitis
Evaluation of Toothbrush Bristles in Plaque Reduction
The purpose of this cross-over clinical research is to evaluate the cleaning efficacy of toothbrushes tufted with two types of tapered bristles and end rounded bristles in removal of interdental plaque with clinical measurement…
- Trial name
- NCT04681885
- Testing
- Tapered bristles A, Tapered bristles B, End rounded bristles
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sunstar Americas
Gingivitis, Orthodontic Appliance Complication
Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment
Orthodontic treatment with fixed appliances can be necessary to correct malocclusions in adolescence or adulthood. It its known that orthodontic treatment induces aseptic pseudo-inflammatory reactions.
- Trial name
- NCT04598633
- Testing
- Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289)
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
Gingivitis
Efficacy of an Amine and Zinc Lactate - Containing Mouthrinse in the Home-based Treatment of Plaque-induced Gingivitis in Adolescents.
The goal of this clinical trial is to evaluate if the adjunctive use of an amine and zinc lactate - containing mouthrinse may give significant benefits in the home-based treatment of plaque-induced gingivitis in adolescents.
- Trial name
- SPA (NCT06671106)
- Testing
- toothbrushing, flossing, Toothpaste Product
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Università degli Studi di Ferrara
Gingivitis
Study of the Anti-Inflammatory Effects of Colgate Total® During an Experimental Gingivitis Model
This study evaluates the anti-inflammatory effects of Colgate Total® during an experimental gingivitis model developed by Löe et al.
- Trial name
- NCT01799226
- Testing
- Toothpaste without triclosan, Triclosan
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Gingivitis, Oral Health Care
Theranovis Dental Gel in Patients With Gingivitis
The aim of this randomized, blinded, controlled study is to compare the theranovis dental gel with a placebo product in order to determine whether an improvement in oral health can be achieved in patients with gingivitis.
- Trial name
- NCT07641192
- Testing
- theranovis dental gel group
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Graz
Gingivitis
Evaluation of the Addition of an Interdental Cleaning Device to Manual Brushing on Gingival Health
This study evaluates the addition of an interdental cleaning device paired with a manual toothbrush compared to using a manual toothbrush only. Plaque removal, reduction of gingival bleeding and reduction of gingival inflammation.
- Trial name
- NCT02836223
- Testing
- Interdental cleaning device, Manual Tooth brush
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Gingivitis
The Effects of Green Tea and Salvadora Persica L. in Patients With Gingivitis
Gingivitis is an inflammatory condition of the gingival tissue, most commonly caused by bacterial infection.The plaque control is considered the most important preventive factor concerning caries, gingivitis, and periodontitis…
- Trial name
- NCT06211309
- Testing
- co.mouthwas, Kin, Distilled water
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Adolescent Behavior, Dental Plaque
Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)
This is a Phase III, randomized, one-center, three arm parallel group, open label and single blind clinical study to evaluate the effectiveness of a cognitive behavioral intervention (CBI) adjunctive to a smart powered toothbrush…
- Conditions
- Adolescent Behavior, Dental Plaque, Gingivitis, Cognitive Change
- Trial name
- NCT05782348
- Testing
- Cognitive behavioral intervention, Colgate smart toothbrush
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Howard University
Gingivitis, Dental Plaque
Comparison Of Clinical Effects Of Listerine And Chlorhexidine Mouth Wash In Patients Undergoing Fixed Orthodontic Treatment
This randomized clinical trial aims to compare the effectiveness of Listerine and Chlorhexidine mouthwashes in improving periodontal health in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07119840
- Testing
- Listerine Mouthwash Product, Chlorhexidine mouthwash
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Oral Health
Effect of Aloe Vera Mouthwashes on the Oral Health of Children
Prevention of dental problems by controlling plaque is the best solution to maintain oral health and prevent high cost of dental treatments.
- Trial name
- NCT04009616
- Testing
- Aloe Vera mouthwash, Chlorhexidine mouthwash
- Where
- Syria
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Damascus University
Periodontal Disease, Periodontal Diseases Inflammation
Comparative Evaluation of Oxygen-enriched and Chlorohexidine Mouthwashes as an Adjunct to Non-surgical Periodontal Therapy and Its Efficacy on Gingival Inflammation, Plaque Scores and Patient-reported Outcomes
comparison between CHX and oxygen-enriched mouthwash
- Conditions
- Periodontal Disease, Periodontal Diseases Inflammation, Gingivitis, Mouthwash
- Trial name
- NCT07861880
- Testing
- CHX mouthwash, Oxygen-enriched mouthwash
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University