Clinical trials: Germ Cell Neoplasm
Melanoma
iToBoS: Clinical Data Acquisition Study
The (overarching) iToBoS Project involves 18 research partners spanning the European Union (including UK and Israel), and 1 Australian partner.
- Trial name
- iToBoS (NCT05075356)
- Testing
- The intelligent total body scanner (iToBoS)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Heathy Volunteer, Parkinsonian Syndromes
Ultralow Dose PET Imaging of 18F-FDOPA
The goal of this clinical trial is to evaluate an investigational ultralow dose PET imaging technique for Parkinsonian syndromes, neuroendocrine tumors, and gliomas detection and monitoring.
- Conditions
- Heathy Volunteer, Parkinsonian Syndromes, Neuroendocrine (NE) Tumors, Gliomas
- Trial name
- NCT07542158
- Testing
- 18F-FDOPA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Akiva Mintz
Melanoma, Cancer Survivorship
Mentored Community Gardening for Individuals With Skin Cancer
The investigators will conduct a single-arm pilot feasibility trial of mentored community gardening for melanoma survivors integrating dosimeters and accelerometers.
- Conditions
- Melanoma, Cancer Survivorship, Skin Cancer, Basal Cell Carcinoma
- Trial name
- H4H2-AZ (NCT05648604)
- Testing
- Mentored Community Gardening
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Neuroendocrine Neoplasm
A Study of 18F-AlF-NOTA-octreotide PET/CT for Imaging Neuroendocrine Neoplasms
The aim of this study is to investigate the clinical value of [18F]aluminum fluoride-1,4,7-triazacyclononane-1,4,7-triacetic acid-octreotide（18F-AlF-NOTA-octreotide ） positron emission tomography / computed tomography (PET/CT) in…
- Trial name
- NCT03511768
- Testing
- 18F-AlF-NOTA-octreotide, PET/CT
- Where
- China
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Malignant Glioma, Anxiety
Psychological Intervention For Brain Tumor Caregivers
This study is testing a supportive psychosocial intervention for caregivers of people who have malignant brain tumors such as gliomas or other high-grade primary brain tumors.
- Conditions
- Malignant Glioma, Anxiety, Caregiver Burden, Malignant Brain Tumor
- Trial name
- NCT04109209
- Testing
- Psychosocial Intervention Group, Usual Care Group
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Melanoma
Community Based Strategies for Early Detection of Melanoma
The purpose of this study is to pilot the use of community education and digital dermatology to increase the early detection of curable melanomas.
- Trial name
- NCT04799106
- Testing
- Community Based Strategies for Early Detection of Melanoma
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Glioma, Glioma of Brain
Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently
Functional magnetic resonance imaging (fMRI) is a non-invasive test used to detect changes in brain activity by taking picture of changes in blood flow. The imaging helps doctors better understand how the brain works.
- Conditions
- Glioma, Glioma of Brain, Glioma of Spinal Cord
- Trial name
- NCT03496181
- Testing
- Multilingual Aphasia Examination, Language paradigms + RS fMRI, Language paradigms + RS fMRI + one anatomical sequence
- Where
- 3 sites in United States, Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Brain Tumor, Glioma
Gliogene: Brain Tumor Linkage Study
The goal of this research study is to investigate the role of genes that may point to a higher risk of developing a glioma. Researchers will use new gene mapping techniques to study how high-risk factors are passed on through a…
- Trial name
- NCT00418899
- Testing
- Questionnaire
- Where
- 15 sites in United States, Denmark and 4 more
- Volunteers
- 17,080 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Melanoma, UV Ray Skin Damage
A Sunscreen Based on Bioadhesive Nanoparticles
The initial focus of the study will be on safety, sun protection factor (SPF) characterization, and substantivity (duration of protection) studies.
- Trial name
- NCT02668536
- Testing
- Standard Sunscreen, BNP
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Yale University
Medullary Thyroid Carcinoma
Research on the Application of 68Ga-DOTA-CCK-FS PET/CT in MTC
This study explores the clinical application of 68Ga-DOTA-CCK-FS PET/CT in detecting cholecystokinin-2 receptor (CCK-2R)-positive tumors, particularly medullary thyroid cancer (MTC) and other malignancies. Led by Prof.
- Trial name
- NCT07138716
- Testing
- 68Ga-DOTA-CCK-FS PET/CT
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Luo Yaping
Sleep Disorders, Circadian Rhythm, Craniopharyngioma
Sleep Wake and Melatonin Pattern in Craniopharyngioma
The hypothalamus is a part of the brain containing a number of nuclei with a variety of functions. It is central in the regulation of hormone secretion, sleep, and circadian functions.
- Trial name
- NCT01881854
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ovarian Cancer
Glycan Analysis in Diagnosing Cancer in Women With Ovarian Epithelial Cancer and in Healthy Female Participants
RATIONALE: New diagnostic procedures, such as glycan analysis, may be effective in finding ovarian epithelial cancer. PURPOSE: This clinical trial is studying how well glycan analysis works in diagnosing cancer in women with…
- Trial name
- NCT00628654
- Where
- United States
- Volunteers
- 581 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Skin Cancers - Basal Cell Carcinoma, Skin Cancers - Squamous Cell Carcinoma
An Observational Study Using The LumAssure Device In Participants Undergoing Assessment Of Skin Conditions.
This is an observational study in adult males and females utilising skin condition measurements using the LumAssure Raman device.
- Conditions
- Skin Cancers - Basal Cell Carcinoma, Skin Cancers - Squamous Cell Carcinoma, Melanoma of Skin, Inflammatory Dermatoses
- Trial name
- NCT06661577
- Where
- 2 sites in New Zealand
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Hydatidiform Moles
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles
The researchers' laboratory is studying a rare class of highly recurrent hydatidiform moles. These are usually complete hydatidiform moles (CHM), but sometimes they are partial hydatidiform moles PHM).
- Trial name
- NCT01008501
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Melanoma
Digital vs. Printed Photographs: Impact on Skin Self-Examinations
The primary aim is to determine the impact of using digital photographs on a mobile device versus printed photographs on skin self-examination rates.
- Trial name
- NCT02520622
- Testing
- Digital photographs loaded onto a mobile device, Skin exam reminders, Social support network
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Breast Cancer, Ovarian Cancer
Investigating the Diagnostic Potential of Tear Proteins in Cancer - A Pilot Study
This Pilot Study is to investigate the tear proteins in a multitude of cancer types and indulge in biomarker discovery to manufacture simple, accurate, and novel tear-based diagnostic tests.
- Conditions
- Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer
- Trial name
- NCT05223218
- Testing
- Schirmer strip, a Class I Medical Device typically used to test for dry eye.
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Namida Lab
Glioblastoma Multiforme, Anaplastic Astrocytoma
Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma
This study will offer a safe treatment for patients with relapsing recurring glioblastoma (GBM) or anaplastic astrocytoma (AA). The trial will test the hypothesis that Erlotinib (Tarceva, OSI-774) can be safely used up to a dose…
- Trial name
- NCT00301418
- Testing
- Erlotinib
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Glioblastoma, Glioblastoma Multiforme
Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBM
This study assesses the safety of using tissue autograft of a pedicled temporoparietal fascial (TPF) or pericranial flap into the resection cavity of newly diagnosed glioblastoma multiforme (GBM) patients.
- Conditions
- Glioblastoma, Glioblastoma Multiforme, GBM, Brain Cancer
- Trial name
- NCT03630289
- Testing
- Tissue autograft of pedicled temporoparietal fascial (TPF) or pericranial flap to bypass the blood brain barrier (BBB)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Melanoma
The Response of Serum 25-Hydroxyvitamin D to Incidental Ultraviolet Light Exposure
1.1 To detect reproducible variations of serum 25-hydroxyvitamin D levels throughout the course of one year in relationship to objectively measured levels of ultraviolet exposure.
- Trial name
- NCT00832533
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- New Mexico Cancer Research Alliance