Clinical trials: Geriatric Population
Glaucoma, Glaucoma, Open-Angle
Prevalence of Glaucoma and Normative Data of Ocular Biometry in Elderly Population in Bangkok
The BANMOP eye study is an ophthalmic subproject of the Bangkoknoi Model Project (BANMOP), a community-based initiative integrating electronic health databases with population surveys to sup-port context-specific health promotion…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma, Suspect, Glaucoma, Angle-Closure
- Trial name
- BANMOP (NCT07763288)
- Where
- Thailand
- Volunteers
- 1,470 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Elderly, Balance
Effects of Non-immersive Virtual Reality Training Compared to Otago Exercise Program on Balance and Spatiotemporal Gait Parameters in Elderly Population
Falling is a serious concern for the growing elderly population due to age-related decline in physical function, leading to injuries, loss of independence, and a decline in overall well-being.
- Conditions
- Elderly, Balance, Gait, Virtual Reality
- Trial name
- NCT06672354
- Testing
- Otago Exercise Program, Non-Immersive Virtual Reality Training
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
KIDNEY TRANSPLANTATION
Comparison of Two Tacrolimus Based Immunosuppressive Regimens in Recipients Receiving Marginal Donor Kidneys
The purpose of this study is to explore the safety and efficacy of two different immunosuppressive regimens (sequential tacrolimus/mycophenolate mofetil [MMF] plus steroids versus tacrolimus plus MMF, following induction with…
- Trial name
- TIGRE (NCT00321113)
- Testing
- tacrolimus, mycophenolate mofetil, steroids
- Where
- 14 sites in Italy
- Volunteers
- 142 people
- Sponsor
- Astellas Pharma Inc
Epidemic Meningitis, Meningococcal Vaccines
Phase Ⅲ Trial of Group ACYW135 Meningococcal Conjugate Vaccine in Children Aged 2-6 Years
The goal of this clinical trial is to evaluate the immunogenicity and safety of an investigational group ACYW135 meningococcal conjugate vaccine in healthy children aged 2 to 6 years.
- Trial name
- NCT07505888
- Testing
- experimental vaccine, active comparator vaccine
- Where
- China
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Cystic Fibrosis, Homozygous for the F508del CFTR Mutation
A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation
The primary objective of the study was to evaluate the efficacy of lumacaftor in combination with ivacaftor at Week 24 in participants aged 12 years and older with cystic fibrosis (CF) who are homozygous for the F508del mutation…
- Trial name
- TRAFFIC (NCT01807923)
- Testing
- Lumacaftor Plus Ivacaftor Combination, Ivacaftor
- Where
- 89 sites in United States, Australia and 9 more
- Volunteers
- 559 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Colon Cleansing
Safety, Efficacy, and Tolerance of Pico-Salax for Colon Cleansing Prior to Colonoscopy in an Elderly Population
This study aims to further define the appropriate population for Pico-Salax, a purgative used prior to colonoscopy. Patients over the age of 70 years with normal renal function scheduled for colonoscopy will receive Pico-Salax…
- Trial name
- NCT00906217
- Volunteers
- 50 people
- Sponsor
- Queen's University
Group B Streptococcal Infections
Study to Evaluate the Safety, Tolerability and Immunogenicity of Three Doses of GBS Vaccine in Elderly Participants
The study is a randomised, double-blind, placebo-controlled, parallel group study to evaluate the safety, tolerability and immunogenicity of three doses of GBS NN/NN2 with Alhydrogel® (Recombinant protein vaccine against Group B…
- Trial name
- NCT05782179
- Testing
- GBS-NN/NN2
- Where
- Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Minervax ApS
Dance Therapy Workshop
Impact of the Implementation of Dance Therapy Workshops on the Quality of Life of Dependent Elderly People Institutionalized Within the Establishments of the Univi Group
Dance is a multimodal activity involving motor, cognitive, sensory and sensory-motor skills as well as emotional and social skills.
- Trial name
- Unidance (NCT05436574)
- Testing
- Dance therapy
- Volunteers
- 940 people
- Sponsor
- Centre Médical Porte Verte
Cancer, Cancer-related Problem/Condition
Cancer and Aging Research Group (CARG) Chemotherapy Toxicity Risk Scores in Older Adults With Cancer in China
The goal of this observational study is to learn about the impact of chemotherapy-related toxicity on older cancer patients in China.
- Trial name
- NCT06717178
- Testing
- Chemotherapy
- Where
- 2 sites in China
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital
Healthy Population
Immunogenicity and Safety of MCV4 in Volunteers Aged 6 Months-5 Years
The purpose of this study is to evaluate the immunogenicity and safety of Group ACYW135 Meningococcal Polysaccharide Conjugate Vaccine in healthy volunteers aged from 3 months to 5 years old.
- Trial name
- NCT06314685
- Testing
- Group ACYW135 Meningococcal Polysaccharide Conjugate Vaccine, Group A and C Meningococcal Polysaccharide Vaccine, Group ACYW135 Meningococcal Polysaccharide Vaccine
- Where
- China
- Volunteers
- 2,450 people, healthy volunteers welcome
- Sponsor
- Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd
Rectal Cancer
External Beam Radiotherapy Combined With Endorectal High-dose-rate Brachytherapy in Elderly and Frail Patients With Rectal Cancer
ACO/ARO/AIO-22 - External beam radiotherapy combined with endorectal high-dose-ratebrachytherapy in elderly and frail patients with rectal cancer. A prospective multicentre trial of the German Rectal Cancer Study Group.
- Trial name
- ACO/ARO/AIO-22 (NCT06729645)
- Testing
- radiotherapy
- Where
- 4 sites in Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital of Cologne
Type 2 Diabetes
The Effect of the Interdisciplinary Care Approach on General Health Parameters in Older Adults With Type 2 Diabetes
The aim of the study was evaluation of the effect of the clinical Pilates, nurse coaching and Peer group work Approach on General Health Parameters in older adults with Diabetes.
- Trial name
- NCT07165119
- Testing
- Interdisciplinary group, Clinical Pilates Group, Nurse Coaching group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Child Behavior
Trial of KEEP-P, a Preventive Intervention for Foster Preschoolers (KEEP-P)
Randomized Trial of KEEP-P, a Preventive Intervention for Foster Preschoolers (KEEP-P). The goal of the proposed study is to conduct a randomized clinical trial of a new, low-cost, manualized, group-based intervention for…
- Trial name
- KEEP-P (NCT03106636)
- Testing
- KEEP-P, KEEP-P+
- Where
- United States
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Quality of Life, Depression
Group Drumming for Improving the Health of Community-Dwelling Elderly
The study seeks to examine the effects that recreational group drumming has on the health of the community- dwelling elderly. It is hypothesized that it has positive and sustainable effects on various health outcome measures.
- Conditions
- Quality of Life, Depression, Sleep, Blood Pressure
- Trial name
- NCT06489834
- Testing
- Group Drumming
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Elderly
Manual Ability Index in Elderly Population
The aim of this study is to conduct a Turkish validity and reliability study of the hand ability scale in the elderly population.
- Trial name
- NCT06083805
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Memory Decline, Cognitive Decline
Anti-inflammatory Probiotics in Cognitive Functioning
The goal of this study is to explore the potential impact of an anti-inflammatory probiotic mixture of psychobiotics including Bifidobacterium longum Rosell®-175 and Lactobacillus helveticus Rosell®-52 on cognitive functions in…
- Conditions
- Memory Decline, Cognitive Decline, Cognitive Aging
- Trial name
- CoProM (NCT07165977)
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Geriatrics
Comparative Effects of Modified Otago and Frenkel's Exercises in Geriatric Population
The goal of this randomized clinical trial is to compare the effects of modified Otago and Frenkel's exercises on balance, motor function, fear of fall and quality of life in the geriatric population.
- Trial name
- NCT06460337
- Testing
- Modified Otago exercises, Frenkel's exercises
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Ceftazidime-avibactam
Individualized Precision Therapy With Ceftazidime and Avibactam Guided by PK/PD in Geriatric Populations
Ceftazidime-avibactam is a β-lactam/β-lactamase inhibitor combination treatment which has been developed to address infections caused by ESBL-, AmpC- and serine carbapenemase-producing Gram-negative bacteria.
- Trial name
- NCT07494981
- Testing
- liquid chromatography-tandem mass spectrometry
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
COVID-19
Study on Sequential Immunization of Omicron Inactivated COVID-19 Vaccine and Prototype Inactivated COVID-19 Vaccine in Population Aged 18 Years Old and Above
This is a randomized, double blind, positive controlled study to evaluate the safety and immunogenicity of Omicron COVID-19 Vaccine (Vero Cell), Inactivated in population aged 18 years old and above who have been vaccinated with…
- Trial name
- COVID-19 (NCT05374954)
- Testing
- Omicron COVID-19 Vaccine (Vero Cell), Inactivated, COVID-19 Vaccine (Vero Cell), Inactivated
- Where
- 10 sites in China
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Aged, 80 and Over, Resistance Training
Resistance-type Exercise Training in the Older Population
Background: Aging is associated with muscle mass and strength loss and "oldest" old people (≥85 y) are at a far greater risk of developing sarcopenia.
- Trial name
- RETO (NCT04999501)
- Testing
- Prolonged resistance-type exercise training
- Where
- Chile
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera