Clinical trials: Geriatric Patient
Removable Dental Prosthesis, Dental Restoration
Impact on General Functionality of an Immediate Prosthetic Functionalization Protocol in People Over 70 Years of Age With Deficient Removable Prostheses
Title: Evaluation of the impact on general functionality of the application of an immediate prosthetic functionalization protocol, in patients with deficient removable prostheses, compared with the conventional treatment that is…
- Conditions
- Removable Dental Prosthesis, Dental Restoration, Elderly, Functional Status
- Trial name
- NCT05595304
- Testing
- prosthetic refunctioning, conventional prosthetic treatment
- Where
- Chile
- Volunteers
- 108 people
- Sponsor
- Gerardo F Fasce Pineda, MD
Endothelial Dysfunction
Efficacy and Safety Study of Policosanol
The purpose of this study is to assess the clinical efficacy and safety of policosanol on elderly patients with endothelial dysfunction
- Trial name
- NCT02543099
- Testing
- policosanol
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Chinese Armed Police Forces
Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come back (relapsed).
- Trial name
- NCT04546399
- Testing
- 3-Dimensional Conformal Radiation Therapy, Asparaginase Erwinia chrysanthemi, Biospecimen Collection
- Where
- 227 sites in United States, Australia and 2 more
- Volunteers
- 461 people
- Sponsor
- National Cancer Institute (NCI)
Anesthesia
Remifentanil and Midazolam on Propofol for Loss of Consciousness in Elderly Patients
Propofol is a well-known induction agent which can provide sound and quick hypnosis with anti-emetic effects. However, dose dependent hypotension or bradycardia have reported while using this agent.
- Trial name
- NCT02818387
- Testing
- Propofol, Remifentanil, Midazolam
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Gangnam Severance Hospital
Malnutrition
Evaluation of Effectiveness of Nutritional Practical Counseling for Elderly Patients at Risk of Malnutrition on Nutritional Status at Home
At hospital, short term actions are used (adaptation of meals, oral supplementation…) to fight malnutrition. Oral supplementation can have a positive impact on weight gain.
- Trial name
- NutriPratiC (NCT02796521)
- Testing
- dietary counseling, nutritional workshop with enrichment during a meal
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Grenoble
Psychological Distress
UP-GRADE: Assessment Pathways for Psychopathological Aspects and Psychological Support in the Adolescent Population
The objective of the observational study "UP-GRADE: Assessment of Psychopathological Aspects and Psychological Support in the Adolescent Age Group of the Population.
- Trial name
- NCT07375784
- Testing
- Q-PAD questionnaire
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Y-balance, Patellofemoral Pain Syndrome
Assessing Lower Extremity Dynamic Stability in Middle-Aged and Elderly Patients With Patellofemoral Pain Using the Y-Balance Test
Background: Patellofemoral pain syndrome (PFPS) is a common functional disorder of knee joint. Its etiology involves biomechanical abnormalities and dynamic stability defects.
- Trial name
- NCT07068984
- Testing
- Differences between lower limb balances were assessed by the Y-Balance test
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Motivational Interviewing, Health Care Seeking Behavior
The Effect of Motivational Interviewing-Based Health Behavior Training in Chronically Ill Migrant Women
This randomized controlled experimental study will be conducted to investigate the effect of health seeking behavior training based on motivational interviewing techniques on health seeking behaviors, illness self-management and…
- Conditions
- Motivational Interviewing, Health Care Seeking Behavior, Migrants, Women
- Trial name
- NCT06505707
- Testing
- Health Seeking Behavior Training Based on Motivational Interviewing Techniques
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kahramanmaraş İstiklal University
Solid Neoplasm
Geriatric Assessment in Predicting Chemotherapy Toxicity and Vulnerabilities in Older Patients With Cancer
This randomized clinical trial studies a geriatric assessment intervention in predicting chemotherapy toxicity and vulnerabilities (or weakness) in older patients with cancer.
- Trial name
- NCT02517034
- Testing
- Comprehensive Geriatric Assessment, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 600 people
- Sponsor
- City of Hope Medical Center
Acute Myeloid Leukemia
Decitabine and Plerixafor in Elderly Acute Myeloid Leukemia (AML)
The hypothesis of this proposal is that combining plerixafor, an inhibitor of stromal cell derived factor - 1α (SDF-1α), with decitabine, a DNA methyltransferase inhibitor, as induction and postremission therapy for older…
- Trial name
- NCT01352650
- Testing
- plerixafor, decitabine
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Weill Medical College of Cornell University
Muscle Weakness, Gait, Unsteady
High Intensity Interval Training in Geriatrics
This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.
- Trial name
- HIITERGY (NCT02318459)
- Testing
- high intensity interval training-HIIT, Traditionnal group rehabilitation
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Gait, Fall
Feasibility of Fabric Orthosis for Knee Support in Elderly Gait Improvement
This pilot clinical trial assesses the safety and feasibility of a novel fabric-type orthosis designed to mimic the knee extensor muscles and improve gait in elderly patients with mobility impairments due to conditions like…
- Conditions
- Gait, Fall, Orthotic Devices
- Trial name
- NCT06387459
- Testing
- Fabric-Type Knee Extensor Muscle-Mimicking Orthosis
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Ischemic Stroke, Transient Ischemic Attack (TIA)
Ambulatory Stroke Unit Treatment for Elderly Patients
ARTIFICE is a prospective, multicenter, randomized, controlled, exploratory non-inferiority trial evaluating whether an ambulatory stroke unit model (aSU) is non-inferior to conventional inpatient stroke unit care (SU) in…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack (TIA), Retinal Ischemia
- Trial name
- ARTIFICE (NCT07420374)
- Testing
- Ambulatory Stroke Unit Care, Conventional Stroke Unit Care
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- University Hospital Heidelberg
Non-Small Cell Lung Cancer
Cancer of the Lung And SeneScencE - Prospective Cohort 1
The main objective is to identify and assess the predictive value of ageing and senescence biomarkers (methylome, telomeres, inflammageing) and senescent cells in tissues to improve prognosis assessment older patients with…
- Trial name
- CLASSE-P1 (NCT06923618)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 385 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation
The Effect and Safety of Different Intensity Anticoagulation Therapy in Elderly Patients With Non-valvular Atrial Fibrillation
Current guidelines recommend standard warfarin anticoagulation international normalized ratio (INR) goal of 2.0-3.0 in adults with non valvular atrial fibrillation (NVAF).
- Trial name
- NCT01438580
- Testing
- Warfarin, aspirin
- Where
- China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Coronary Artery Disease
Symptom Management Intervention in Elderly Coronary Artery Bypass Patients
The major purpose of this experimental study is to test the effects of the symptom management home care nursing intervention (SMHCNI) on recovery outcomes of elderly CABG patients, using a randomized, two group (n=284) repeated…
- Trial name
- NCT00572988
- Volunteers
- 232 people
- Sponsor
- University of Nebraska
Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality
Transthoracic Echocardiography of Inferior Vena Cava Before Spinal Anesthesia Can Predict Hypotension
Study Protocol: Outcome Measurements Primary Outcome The main outcome will be the preoperative performance of the dIVCmax/IVCCI ratio to foresee the incidence of hypotension after spinal anesthesia in a greater extent to that of…
- Conditions
- Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality, Intraoperative Complications
- Trial name
- NCT03266250
- Testing
- spinal anesthesia
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Postoperative Cognitive Dysfunction
Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical Prostatectomy
Evaluation of the effect of preoperative intravenous administration of amantadine sulfate on the prevention of the development of early cognitive dysfunction in elderly patients undergoing laparoscopic radical prostatectomy
- Trial name
- NCT03988010
- Testing
- Amantadine Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- TC Erciyes University
Lactose Intolerance
Evaluation of LacTEST for the Diagnosis of Hypolactasia in Adults and Elderly Patients Presenting With Clinical Symptoms of Lactose Intolerance
The purpose of this study is to evaluate both the impact of LacTEST on diagnostic thinking and on patient management, and its reproducibility (Test-Retest), for the diagnosis of hypolactasia in adults and elderly patients…
- Trial name
- NCT02636413
- Testing
- gaxilose, lactose
- Where
- 6 sites in Spain
- Volunteers
- 1 people
- Sponsor
- VenterPharma
Non-carious Cervical Lesions, Geriatric Patients
the Clinical Performance of a Moisture Resistant, M-TEG-P Phosphate Monomer Based Universal Adhesive (YAMAKIN TMR-Aquabond0) Compared to the Conventional Universal Adhesive (3m ESPE Single Bond Universal Adhesive)
this trial is to test the clinical performance of a novel moisture resistant, M-TEG-P phosphate monomer based universal adhesive (YAMAKIN TMR-Aquabond0) compared to the conventional universal adhesive (3m ESPE Single Bond…
- Trial name
- NCT05029479
- Testing
- Bonding in NCCLs
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University